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20621
Near-infrared spectroscopy–guided personalized repetitive transcranial magnetic stimulation for bipolar depression: a case report
Published 2025-01-01“…IntroductionTranscranial magnetic stimulation (TMS) is a common treatment for depression, particularly in patients unresponsive to conventional therapies. High-frequency (10 Hz), low-frequency (1 Hz), or bilateral (left, high-frequency; right, low-frequency) stimulation of the dorsolateral prefrontal cortex (DLPFC) has been demonstrated to be effective in studies based on prefrontal asymmetry theory, which suggests that depression is associated with reduced left frontal function and increased right frontal function. …”
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20622
PARP‐1 Inhibition Increases Oxidative Stress in Ets‐1‐Expressing MDA‐MB‐231 Breast Cancer Cells
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20623
The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer
Published 2024-11-01“…Pharmacological regulation of NOTCH1 is promising in tumor immunotherapy, whereas the effective rate of existing therapies remains low. NOTCH1 functions, as a cancer suppressor or a cancer promoter in different cancers, is engaged in the crosstalk between the immune microenvironment and cancer cells, posing a major challenge to immunotherapy. …”
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20624
Changes in the use practitioner-based complementary and alternative medicine over time in Canada: Cohort and period effects.
Published 2017-01-01“…<h4>Conclusion</h4>The higher CAM use over time and in recent cohorts could reflect how recent generations are approaching their healthcare needs by expanding conventional care to include CAM therapies and practice for treatment and health promotion. …”
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20625
Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities
Published 2025-01-01“…Future approaches to OC treatment must focus on personalized strategies that target the inflammatory TME, integrating anti-inflammatory therapies with immunotherapy to enhance patient outcomes. …”
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20626
Immune Cells and Intracerebral Hemorrhage: A Causal Investigation Through Mendelian Randomization
Published 2025-01-01“…This breakthrough paves the way for innovative clinical and pharmaceutical research opportunities, potentially promoting the development of targeted therapies and enhanced strategies for managing and preventing ICH.…”
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20627
PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration
Published 2025-02-01“…Abstract Intervertebral Disc degeneration (IDD) is one of the leading causes of disability, and current therapies are ineffective. Phosphodiesterase 4B (PDE4B) plays an essential role in regulating the activation of nuclear factor E2-related factor 2 (Nrf2), while Nrf2 regulates ferroptosis. …”
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20628
Clinical Guidelines for Acupotomy Treatment of Knee Osteoarthritis
Published 2023-06-01“…The treatment plan specifies the principles of treatment, the operational steps, the selection of treatment points, other synergistic therapies and other aspects of the treatment techniques. …”
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20629
EFFECT OF IRRIGATION INTERVAL ON GROWTH AND ARTEMISININ CONTENT OF WORMWOOD (Artemisia annua L.) CHEN YOUNG VARIETY IN SOKOTO
Published 2024-12-01“…Artemisinin is the main antimalarial compound in Artemisia annua, used in the formulation of artemisinin-based combined therapies (ACT) to treat malaria. Artemisinin is largely obtained from A. annua plant but the content is very low and its production commercially is not cost effective worldwide. …”
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20630
Perceptions in 3.6 Million Web-Based Posts of Online Communities on the Use of Cancer Immunotherapy: Data Mining Using BERTopic
Published 2025-02-01“…Six themes were identified, primarily covering (1) hopeful prospects offered by immunotherapy, (2) perceived effectiveness of immunotherapy, (3) complementary therapies or self-treatments, (4) financial and mental impact of undergoing immunotherapy, (5) impact on lifestyle and time schedules, and (6) side effects due to treatment. …”
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20631
Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms
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20632
Cost-effectiveness and budget impact analysis of peritoneal dialysis and haemodialysis in South Africa
Published 2025-01-01“…Haemodialysis (HD), peritoneal dialysis (PD), and kidney transplant are the three main modalities used for managing end stage kidney disease. The cost of these therapies poses a significant burden to the health care system in South Africa. …”
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20633
Epidemiology of clinically significant migraine in Israel: a retrospective database study
Published 2025-02-01“…Clinically significant migraine patients were identified using stringent criteria, including repeated diagnostic codes for migraine, confirmation by a neurologist, or the use of migraine-specific therapies. Each migraine patient was matched 1:1 with a control individual of similar age, sex, socioeconomic status, and ethnic background. …”
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20634
Identification of tacrolimus-related genes in familial combined hyperlipidemia and development of a diagnostic model using bioinformatics analysis
Published 2025-02-01“…Additionally, it provides research directions for identifying potential targets for clinical therapies.…”
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20635
Designing an intervention to improve cognitive evaluations in primary care
Published 2025-01-01“…For some patients, early detection of cognitive impairment enables access to disease-modifying therapies. For all patients, it allows access to psychosocial supports. …”
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20636
Human Muscle Progenitor Cells Displayed Immunosuppressive Effect through Galectin-1 and Semaphorin-3A
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20637
Meta-analysis of Efficacy and Safety of Fire Acupuncture in Treatment of Ganglion Cyst
Published 2019-08-01“…The Meta-analyses demonstrated that the total rate of the fire needle group was significantly higher than that of the other treatment groups[<italic>OR</italic>=3.41, 95%<italic>CI</italic>(1.93, 6.04), <italic>P</italic>< 0.01]; the cyst diameter was smaller than that of the other treatment groups[<italic>MD</italic>=-0.35, 95%<italic>CI</italic>(-0.38, -0.32), <italic>P</italic>< 0.01]; the recurrence rate of the fire needle group was lower than that of the other treatment groups[<italic>OR</italic>=0.08, 95%<italic>CI</italic>(0.03, 0.25), <italic>P</italic>< 0.01]; the incidence rate of postoperative infection in the fire needle group was lower than the other treatment groups[<italic>OR</italic>=0.09, 95%<italic>CI</italic>(0.01, 0.71), <italic>P</italic>< 0.05]; the incidence rate of adverse reactions in the fire needle group was less than the other treatment groups[<italic>OR</italic>=0.09, 95%<italic>CI</italic>(0.02, 0.46), <italic>P</italic>< 0.01].Conclusion:The efficacy and safety of fire acupuncture in the treatment of ganglion cysts are superior to other therapies. However, due to the limited number of documents included, the above conclusions need more rigorous RCTs for further verification.…”
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20638
The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype
Published 2019-01-01“…Uncultured mesenchymal stromal cells (MSCs) are increasingly used in therapies; however, the effects of donor age on their biological characteristics and gene expression remain unclear. …”
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20639
The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients
Published 2024-03-01“…**Conclusions:** Patients with nAMD continue to experience more vision impairment and worse functional status compared with a similar population of Medicare beneficiaries despite availability of therapies like antivascular endothelial growth factor to treat retinal disease.…”
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20640
Effect of Cinnamon Essential Oil on the Chemotherapy-Induced Nausea and Vomiting of Cancer Patients
Published 2025-01-01“…In oncology departments, nurses can evaluate the effects of complementary therapies such as use of essential oil on reducing nausea and vomiting of patients undergoing chemotherapy. …”
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