Gene Therapy: A step toward advanced orthodontics – A narrative review by Monika Shukla, Shalu Jain, C. Munish Reddy, Pradeep Raghav, Kumar Amit, Rinchin Yangzom, Shivika Garg, Aastha Kamrani

“…Background: Gene therapy deals with the insertion of exogenous genes into a cell to produce the desired therapeutic effect. After the introduction of gene therapy in dentistry, this field is also flourishing rapidly in the branch of orthodontics and dentofacial orthopedics as it can prevent many prenatal and postnatal dentofacial anomalies which have the genetical etiology. …”
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deutetrabenazine for the treatment of chorea associated with Huntington’s disease by Harshit Gupta, Wil Perkins, Cain Stark, Sathya Kikkeri, Juyeon Kakazu, Adam D. Kaye, Alan D. Kaye

“…Deutetrabenazine is thought to function as an inhibitor of the VMAT2 vesicular monoamine transporter resulting in decreased monoamine release, including dopamine, in the synaptic cleft which has a therapeutic effect in management of chorea. This drug was approved by the FDA in 2017 with a specific indication for tardive dyskinesia and choreiform movement in Huntington’s disease. …”
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A curative effect evaluation of intensity-modulated radiation therapy combined with periorbital triamcinolone acetonide injection in treating thyroid eye disease patients with acti... by Hao Zhang, Weimin He

“…We found that IMRT combined with periorbital triamcinolone acetonide injection has a good therapeutic effect on TED patients with low CAS but significant active extraocular muscles, and there is a significant improvement at 3 months after treatment. …”
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Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica by Rong Guo, Mingming Zhou, Xiaohui Wei, Ling Niu

“…There is no well-recognized treatment standard for TO, and the judgment of therapeutic effect is inconsistent. It is necessary to improve the understanding of this disease from a clinical perspective.…”
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Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits by Xiaoli Shen, Lina Huang, Dahui Ma, Jun Zhao, Yi Xie, Qiang Li, Aineng Zeng, Kun Zeng, Ruyin Tian, Tianfu Wang, Siping Chen

“…This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. …”
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The Relationship between Erythrocytes and Diabetes Mellitus by Yaqi Wang, Peiyuan Yang, Zhaoli Yan, Zhi Liu, Qiang Ma, Zehong Zhang, Yunxia Wang, Yan Su

“…This paper reviews the normal structure and function of erythrocytes, the changes in erythrocytes in patients with diabetes, and the role of erythrocytes in the development of diabetic complications to provide more indicators for the early prevention of DM complications and to monitor the therapeutic effect of DM.…”
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Influence of AGTR1 and ABCB1 Gene Polymorphism on the Curative Effect of Irbesartan by Qiao Wang, Lingsen You, Zeyu Li, Leiyi Zhang, Xueqi Li, Xuesong Yang

“…In this study, we investigated the new combinational influences of AGTR1 and ABCB1 gene polymorphism on the therapeutic effect of irbesartan among Chinese hypertensive patients. …”
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Combination of AAV-CCL19 and GPC3 CAR-T Cells in the Treatment of Hepatocellular Carcinoma by Min Meng, Yi-chen Wu

“…Chimeric antigen receptor-modified T cell (CAR-T) therapy has great potential for treating malignant tumors, especially hematological malignancies. However, the therapeutic effect of solid tumors is limited. One of the most important factors is the homing of CAR-T cells to tumor tissues in vivo. …”
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Integrating pharmacogenetics, multi‐omics and machine learning in the novel therapeutic view of pulmonary hypertension by Chenxi Li, Jipeng Xue, Dongchen Zhou, Xiaomeng Qi, Ting Chen, Zhoubin Li

“…They are widely used in the screening of drug therapeutic targets and predicting drugs therapeutic effect. The emergence of innovative diagnosis and treatment approaches for PH opens pathways for combining personalized medicine with established pharmacological and gene therapies to achieve effective treatment strategies and further decrease the mortality rate associated with this disease.…”
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Analysis of Progress and Challenges of EGFR-Targeted Molecular Imaging in Cancer With a Focus on Affibody Molecules by Weizhi Chen MD, Baozhong Shen MD, PhD, Xilin Sun PhD

“…Epidermal growth factor receptor (EGFR)-targeted cancer therapy requires an accurate estimation of EGFR expression in tumors to identify responsive patients, monitor therapeutic effect, and estimate prognosis. The EGFR molecular imaging is an optimal method for evaluating EGFR expression in vivo accurately and noninvasively. …”
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Profiling Rosmarinic Acid and Sinensetin Content of Orthosiphon aristatus. from Three Different Locations with Variety Ethanol Concentration by Novia Putri Ramadhani, Yosi Bayu Murti, Andayana Puspitasari Gani

“…Orthosiphon aristatus is a well-known medicinal plant acknowledged for its therapeutic effect in treating urinary tract diseases, hypertension, diabetes mellitus, and arthritis. …”
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The Effects of 6 Common Antidiabetic Drugs on Anti-PD1 Immune Checkpoint Inhibitor in Tumor Treatment by Ze-Tao Zhan, Lu Liu, Ming-Zhen Cheng, Yi Gao, Wei-Jie Zhou

“…In particular, acarbose significantly inhibited tumor growth and further enhanced the therapeutic effect of anti-PD1, which can be widely used in tumor therapy. …”
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NaHS modulates astrocytic EAAT2 expression to impact SNI-induced neuropathic pain and depressive-like behaviors by Man-Man Qi, Heng-Yue Peng, Tian-Ge Zhang, Yan Li, Meng-Ya Gao, Wen-Bo Sun, Xu-Peng Wang

“…This study investigated the therapeutic effect of intraperitoneal injection of the H2S donor sodium hydrosulfide (NaHS) on neuropathic pain. …”
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Perbedan Terapi Madu dan Multi Vitamin Terhadap Kadar Hemoglobin, Albumin dan Status Nutrisi Pada Anak Balita by Meri Neherta

“…The conclusion of this research indicates that the therapeutic effect of multivitamins is better than honey therapy combined with vitamin B complex on hemoglobin levels, albumin levels, and nutritional status (w/U) in toddlers in the work areas of Nanggalo Health Center, Padang, in 2011. …”
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Extracorporeal shock wave therapy versus dexamethasone iontophoresis as a treatment for symptomatic knee osteoarthritis by Shimaa Taha Abu El Kasem, Sahar Ahmed Abdalbary, Mohamed I. Mabrouk, Engy Badreldin S. Moustafaa, Asmaa Abonour, Rania R. Mohamed

“…Conclusions ESWT has a superior therapeutic effect in patients with symptomatic KOA.…”
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Application of Nanoparticles in Diagnosis and Treatment of Pancreatic Cancer by Juzheng Yuan, Yang Wang, Yang Cao, Shuqiang Yue, Xiao Li

“…The reconstruction of pancreaticoduodenal papillary duct with nanomaterials has certain advantages for postoperative recovery, reduces postoperative complications, reduces the probability of infection, and improves the therapeutic effect.…”
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Boehmeria nivea Attenuates the Development of Dextran Sulfate Sodium-Induced Experimental Colitis by Eun Ju Shin, Mi Jeong Sung, Hye Jeong Yang, Myung Sunny Kim, Jin-Taek Hwang

“…We examined the therapeutic effect of an ethanol extract derived from Boehmeria nivea (Linn.) …”
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Role of heat shock protein in radiation-induced effect and related potential clinical application by Ying Xu, Wentao Hu, Guangming Zhou

“…This paper reviews the biological effects of HSP under radiation and the latest research progress of combined radiation and HSP inhibitors or hyperthermia, in the hope of having a more comprehensive understanding of its mechanism in physiological processes such as cell survival, apoptosis, inflammation, immune response, as well as radiation response, which will help to enhance the therapeutic effect and to provide more effective and safer radiotherapy for cancer patients in the future.…”
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Proteomic Analysis of Exudates from Chronic Ulcer of Diabetic Foot Treated with Scorpion Antimicrobial Peptide by Zhixiang Tan, Zhiguo Yu, Xiaobo Xu, Lanxia Meng, Mosheng Yu, Rui Tao, Yingliang Wu, Zhanyong Zhu

“…Scorpion peptides have good therapeutic effect on chronic ulcer of diabetic foot, but the related pharmacological mechanism has remained unclear. …”
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Prolonged Exposure Therapy For Post Traumatic Stress Disorder by Levent SÜTÇÝGÝL, Selçuk ASLAN

“…Many studies have shown therapeutic effect of cognitive behavioral therapies on posttraumatic stress disorder, so that these therapies take part in the first step of treatment guides. …”
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