The Role of the Patient Information Leaflet in Patients’Medication Therapy: A Case Study within the Kumasi Metropolis of Ghana by Frederick W. A. Owusu, Genevieve Naana Yeboah, Rahel Adutwiwah Aboagye, Cedric Dzidzor K. Amengor, Philomena Entsie

“…One of the tools used in providing comprehensible medication information to patients on their medication use for improved adherence and subsequent optimal therapeutic effect is the Patient Information (PI) leaflet. …”
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5-Methoxytryptophan Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Intestinal Epithelial Damage and Inflammatory Response by Yanling Wang, Jun Li, Qinyuan Yang, Zhenhang Zhu, Fang Cheng, Xiangyan Ai, Yang Liu, Dongbao Zhao, Futao Zhao, Peng Cheng

“…This study initially confirmed that 5-MTP possessed an excellent therapeutic effect on colitis. 5-MTP inhibits macrophage infiltration and the generation of inflammatory factors. …”
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In Vivo Hypoglycaemic Effect and Inhibitory Mechanism of the Branch Bark Extract of the Mulberry on STZ-Induced Diabetic Mice by Hua-Yu Liu, Meng Fang, Yu-Qing Zhang

“…To understand this therapeutic effect and the regulatory mechanisms of BBE in diabetic mice, a qRT-PCR experiment was performed, indicating that the mulberry BBE can regulate the mRNA expression of glycometabolism genes in diabetic mice, including glucose-6-phosphatase (G6Pase), glucokinase (GCK), and phosphoenolpyruvate carboxykinase (PEPCK), thereby regulating sugar metabolism and reducing the blood glucose level in diabetic mice. …”
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Fabrication of microcapsules with core‐shell structure for oral delivery of dual drugs and real‐time computed tomography imaging by Rong Cai, Long Xiao, Miaomiao Zhang, Lulu Zhao, Jingjing Zhang, Fengyi Du, Zhirong Wang

“…Abstract Although multidrug combinations are an effective therapeutic strategy for serious disease in clinical practice, their therapeutic effect may be reduced because they conflict with each other medicinally in certain cases. …”
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Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit by Maohua Cao, Junaid A. Khan, Bum-Yong Kang, Jawahar L. Mehta, Paul L. Hermonat

“…However, dual hSTAT3/hIL-10 delivery offered no improvement in therapeutic effect. Plasma cholesterol levels in dual hSTAT3/hIL-10-treated animals were statistically higher compared to hIL-10 alone. …”
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Wedelolactone Mitigates Alcoholic Steatohepatitis via Modulating the TLR4/MyD88/NF-κB Pathway by Tao Jiang, Bingde Hu, Yongxia Li, Shuihong Yu

“…Wedelolactone (WEL) has demonstrated anti-inflammatory properties. However, the therapeutic effect and underlying mechanisms of WEL against alcoholic steatohepatitis (ASH) remain unclear. …”
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The Influence of Radiological “Disappearing Lesions” on the Efficacy and Prognosis of Patients with Colorectal Liver Metastases Undergoing Conversion Therapy by Zhi-yang Song, Dong Yang, Yang Liu, Yong Cheng

“…Younger patients, who use chemotherapy alone to achieve a therapeutic effect, might have better survival benefits when the lesions do not progress within 2 years after the appearance of DLMs.…”
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The Anti-Cytokine Storm Activity of Quercetin Zinc and Vitamin C Complex by Hayder B. Sahib, Omer Abid Kathum, Rafal Shakeeb Alanee, Rehab A. M Jawad, Ahmed Majeed Al-Shammari

“…In conclusion, the complex has significantly ameliorated LPS-induced acute lung and kidney injury, largely through suppression of inflammation; the large lethal dose value may make the complex have a promising therapeutic effect in the prevention of cytokine storm.…”
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Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile. by Ahmed M Nagy, Heba A Fahmy, Mohamed F Abdel-Hameed, Rehab F Taher, Alaa M Ali, Mohamed M Amin, Sherif M Afifi, Tuba Esatbeyoglu, Mohamed A Farag, Abdelsamed I Elshamy

“…<h4>Conclusions</h4>These results emphasize the potential therapeutic effect of E. heterophylla on DM related to male infertility and reproductive dysfunctions via its antioxidant/angiogenetic /anti-apoptotic effect.…”
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Non-invasive physical plasma improves conventional wound management of cut and bite wounds in wild European hedgehogs by Jürgen Eichler, Björn Rulik, Alexander Abazid, Matthias B. Stope

“…The advantages are that NIPP has few side effects, is painless and gentle on the tissue. The therapeutic effect is mediated by reactive oxygen species (ROS). …”
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Optimizing the Future: A Game Theory to Tumor Therapeutic Strategies by Fang-Yuan Liu, Xin Liu, Dan-Ni Ding, Shao-Xuan Liu, Jing Xu, Yu-Xin Zhao, Yan-Hong Wang, Feng-Juan Han

“…Results We found that when malignant tumors exhibit vigorous proliferation, doctors should administer Chinese medicine in conjunction with chemotherapy drugs, continuously optimizing the therapeutic effect of the Chinese medicine. Upon reaching a specific threshold in the treatment effect of the Chinese medicine, doctors may appropriately augment the dosage of chemotherapy drugs, building upon the initial regimen. …”
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Low power laser radiation treatment in patients with recurrent aphthous stomatitis by Yety Isabel Rosado Fernández, Edel Alejandro Fonte Vigo, Gilberto Salas Contreras, Nancy Díaz Canedo, Maricelys de la Caridad Hernández Cabeza, Gloria Barroso de Mazarredo

“…<br /><strong>Objective</strong>: to determine the therapeutic effect of treatment with low-power laser radiation in patients diagnosed with recurrent aphthous stomatitis.…”
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Modified ‘Xingnao Kaiqiao’ acupuncture technique shortens the recovery time of comatose patients by Dan Meng, Liangfeng Wang, Shengqiang Cheng, Pan Cai

“…Background This study was conducted to analyse the therapeutic effect of the modified ‘Xingnao Kaiqiao’ acupuncture technique in the recovery of comatose patients, as well as the clinical factors that may influence recovery from coma.Methods Diagnostic and therapeutic data from 166 patients in a coma due to neurological diseases were retrospectively collected. …”
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The Effectiveness and Safety of Probiotic Supplements for Psoriasis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Preclinical Trials by Liuting Zeng, Ganpeng Yu, Yang Wu, Wensa Hao, Hua Chen

“…Prebiotics may have a positive effect on alleviating the clinical symptoms of psoriasis, but a large sample of RCTs is still needed to support its therapeutic effect in psoriasis.…”
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Network Pharmacology Analysis of the Therapeutic Potential of Colchicine in Acute Lung Injury by Fei Sun, Lijuan Zhang, Lulu Shen, Chunman Wang

“…Our findings suggest that colchicine’s therapeutic effect on ALI might derive from its anti-inflammatory properties. …”
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Sickled Erythrocytes Reversal and Membrane Stabilizing Compounds in Telfairia occidentalis by Samuel Atabo, Ismaila Alhaji Umar, Dorcas Bolanle James, Aisha Indo Mamman

“…In south-eastern Nigeria, Telfairia occidentalis (T. occidentalis) is strongly recommended for consumption by SCD patients, owing to its presumed therapeutic effect. This study investigates the antisickling and membrane regenerative potentials of T. occidentalis in sickled erythrocytes. …”
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Optimizing Extractability, Phytochemistry, Acute Toxicity, and Hemostatic Action of Corn Silk Liquid Extract by Zead Helmi Abudayeh, Uliana Karpiuk, Viktoriia Kyslychenko, Qais Abualassal, Loay Khaled Hassouneh, Sami Qadus, Ahmad Talhouni

“…According to these findings, corn silk liquid extract is rich in phytochemicals and possesses a potential therapeutic effect on bleeding disorders. Furthermore, it could be used in the pharmaceutical sciences industry to develop medicines for testing in the treatment of various diseases.…”
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The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…Here, we investigated the therapeutic effect and potential mechanism of human amnion mesenchymal cells (hAMC) on inflammation and remyelination in experimental autoimmune encephalomyelitis (EAE) mice. …”
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The effect of Garcinia livingstonei aqueous leaf extract on hyperglycaemic-induced human sperm cell: An in-vitro study by Murendeni Nethengwe, Kunle Okaiyeto, Chinyerum S. Opuwari, Oluwafemi O. Oguntibeju

“…The findings of this study suggest the potential therapeutic effect of G. livingstonei in the treatment of DM-related male infertility. …”
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Enrichment strategy and initial characterization of heterodimers enriched from a co-formulated cocktail of therapeutic antibodies against SARS-COV-2 by Sophia Liu, Yuetian Yan, Cody M. Secor, Zachary R. Oberholtzer, Donna J. Skow, Mushhood Sheikh, Youmi Moon, Yue Fu, Cristinel Sandu, Shunhai Wang, Ning Li, Jennifer B. Nguyen, Michael P. Rosconi, Erica A. Pyles

“…Co-formulation of multiple drug products is an efficient and convenient approach to simultaneously deliver multiple biotherapeutics with the potentially added benefit of a synergistic therapeutic effect. However, co-formulation also increases the risk of heteromeric interactions, giving rise to unique impurities with unknown efficacy and immunogenicity. …”
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