Developing country demand for crop germplasm conserved by the U.S. National Plant Germplasm System by Kelly Day Rubenstein, Paul W. Heisey

“…NPGS germplasm ranged from final cultivars to crop wild relatives. These respondents requested proportionately more cultivars than are present in the NPGS. …”
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Genetic Variation of Lentil Landraces Across Different Altitudes in Azerbaijan by Babayeva Sevda, Shikhaliyeva Kamila, Qurbanova Qamar, Hajiyeva Sabina, Izzatullayeva Vusala, Rustamov Khanbala, Abbasov Mehraj

“…The aim of this study was to assess the genetic diversity of 50 lentil accessions, including landraces from high mountain regions of Azerbaijan as well as wild lentil species, using SSR markers. DNA was extracted from leaves, amplified by PCR and separated by polyacrylamide gel electrophoresis. …”
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THE PGR NETWORKS IN FRANCE: COLLABORATION OF USERS AND THE GENETIC RESOURCE CENTRE ON SMALL GRAIN CEREALS by A. Didier, L. Bardy, E. Boulat, J. Koenig, A. Lapierre, F. Exbrayat, J. Bordes, F. Balfourier

“…The main species of Triticum (wheat), Hordeum (barley), Secale (rye), ×Triticosecale (triticale), Avena (oat) genera and their wild relatives are held in the collection. By combining phenotypic and genotypic data, the whole genetic resource collection has been structured into smaller functional groups of accessions, in order to facilitate the access and meet the increasing number of different requirements for the distribution of adapted samples of accessions.New panels are being processed to give breeders and scientists new useful tools to study, for instance, stress resistance or to develop association studies. …”
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In Vitro and In Silico Cytotoxic and Antibacterial Activities of a Diterpene from Cousinia alata Schrenk by Almira Zhanzhaxina, Yerlan Suleimen, Ahmed M. Metwaly, Ibrahim H. Eissa, Eslam B. Elkaeed, Raigul Suleimen, Margarita Ishmuratova, Kydyrmolla Akatan, Walter Luyten

“…A biologically guided isolation of secondary metabolites from Cousinia alata Schrenk wild plant growing in Akmola region, Kazakhstan, led to the isolation of the bioactive diterpene grindelic acid (1). …”
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Male bluegill vary in color and behavior relative to their position in a lek by Matthew Peroš, Lakshita Vij, Elana Anavian, Kevin Almeida Arteaga, Fatima Iya Haruna, Aliza Siegman, Wei Fang, Sebastian Gaston Alvarado, Sebastian Gaston Alvarado

“…To test this hypothesis, we quantified color patterns in wild communities of bluegill using computer vision, scored the behavior of lek occupying parental males, and categorically classified lek position as a function of neighboring males. …”
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Mitochondrial-ER Contact Sites and Tethers Influence the Biosynthesis and Function of Coenzyme Q by Noelle Alexa Novales, Hadar Meyer, Yeynit Asraf, Maya Schuldiner, Catherine F. Clarke

“…Given that ER-mitochondrial contact sites coordinate CoQ biosynthesis, we used a Split-MAM (Mitochondrial Associated Membrane) artificial tether consisting of an ER-mitochondrial contact site reporter, to evaluate the effects of artificial membrane tethers on CoQ biosynthesis in both wild-type and ERMES mutant yeast strains. Overall, this work identifies the deletion of COQ11 as a novel suppressor of phenotypes associated with ERMES deletion mutants and indicates that ER-mitochondria tethers influence CoQ content and turnover, highlighting the role of membrane contact sites in regulating mitochondrial respiratory homeostasis.…”
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The Effects of Fenobucarb on the Physiology, Behavior, and Growth of Silver Barb (<i>Barbonymus gonionotus</i>) by Tam Thanh Nguyen, Håkan Berg, Loi Ngoc Nguyen, Yen Thi Hai Nguyen, Cong Van Nguyen

“…Thus, although the use of F in rice farming in the Mekong Delta may not lead to direct fish kills, it impacts the growth and health of the fish, which could have negative implications for wild fish populations and the long-term production of healthy fish in the Mekong Delta.…”
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Mice with NOP2/sun RNA methyltransferase 5 deficiency die before reaching puberty due to fatal kidney damage by Hongya Zhang, Xiaohui Li, Jing Bai, Cong Zhang

“…Therefore, in this study, we investigate the role of NSUN5 in mice.Methods In the present research, we built a mouse model (Nsun5-/-) using the CRISPR/Cas9 system to investigated the specific role of NSUN5.Results We observed that Nsun5-/- mice had a reduced body weight compared to wild-type mice. Additionally, their survival rate gradually decreased to 20% after postnatal day (PD) 21. …”
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Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity by Radka Obořilová, Eliška Kučerová, Tibor Botka, Hana Vaisocherová-Lísalová, Petr Skládal, Zdeněk Farka

“…Finally, the QCM-D biosensor was employed to evaluate the synergistic effect of subinhibitory concentrations of the antibiotic amoxicillin with the bacteriophage P68, enabling monitoring of the lysis of P68-resistant wild-type strain S. aureus RN4220. Our findings suggest that this synergy also impedes the formation of bacterial aggregates, the precursors of biofilm formation. …”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Gang, Roggers, Okello, Denis, Yeongjun, Ban, Kang, Youngmin

“…Adams, popularly referred to as wild sunflower, has been used for generations across several African communities to treat various diseases, including malaria, wounds, osteoporosis, diabetes mellitus, gastric ulcers, measles, tuberculosis, stomach ache, rheumatic pains, and gonorrhea. …”
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The Effect of Wildlife Conservation to the Surrounding Community in Nyamagabe District: A Case Study of Nyungwe National Park. by Vestine, Batamuliza

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Obesity-Induced Methylation of Osteopontin Contributes to Adipogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells by Min Tang, Rui Chen, Hao Wang, Guowei Sun, Fan Yin, Beibei Liang, Yang Yang, Gaowa Sharen, Huafeng Wei, Xuyu Zhou, Gang Huang, Jian Zhao

“…We found that osteopontin (OPN) is downregulated in ASCs and adipose tissues of obese mice and overweight human beings because of methylation on its promoter, indicating that OPN may affect the development of obesity. Silencing of OPN in wild-type ASCs promotes adipogenic differentiation, while reexpression of OPN reduced adipogenic differentiation in OPN−/− ASCs. …”
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Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β by Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen

“…The VHH-scFv fusions were further investigated in mouse models with Aβ pathology, showing higher retention compared to wild-type mice without Aβ pathology. Our findings suggest that these novel VHH-based FPs hold potential for therapeutic and diagnostic applications in AD, providing a strategy to overcome BBB limitations and enhance brain targeting of antibody-based treatments. …”
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Association of Single Nucleotide Polymorphisms in the IL-18 Gene with Production of IL-18 Protein by Mononuclear Cells from Healthy Donors by Khripko Olga Pavlovna, Sennikova Nadegda Sergeevna, Lopatnikova Julia Anatolievna, Khripko Jurii Ivanovich, Filipenko Maxim Leonidovich, Khrapov Evgenii Alexandrovich, Gelfgat Evgenii L'vovich, Yakushenko Elena Vladimirovna, Kozlov Vladimir Alexandrovich, Sennikov Sergei Vitalievich

“…In contrast, PBMC from donors carrying allele 607A showed significant increases in spontaneous and stimulated IL-18 production compared to wild type. Our study suggests that the SNPs −607 and −137 in the promoter region of the IL-18 gene influence the level of IL-18 protein production by PBMC from healthy donors in Southwestern Siberia.…”
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A detoxified TLR4 agonist inhibits tumour growth and lung metastasis of osteosarcoma by promoting CD8+ cytotoxic lymphocyte infiltration by Ryunosuke Oyama, Akira Nabeshima, Makoto Endo, Alexey Novikov, Toshifumi Fujiwara, Capucine Phelip, Nobuhiko Yokoyama, Yoshinao Oda, Martine Caroff, Yoshihiro Matsumoto, Jerome Kerzerho, Yasuharu Nakashima

“…We evaluated tumour growth, lung metastases, and immune cell infiltration in wild-type and TLR4-mutant mice and performed selective immunodepletion. …”
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Vascular Contractility Relies on Integrity of Progranulin Pathway: Insights Into Mitochondrial Function by Shubhnita Singh, Ariane Bruder, Rafael M. Costa, Juliano V. Alves, Sivakama Bharathi, Eric S. Goetzman, Thiago Bruder‐Nascimento

“…Methods and Results We used aortae from male and female C57BL6/J wild‐type (PGRN+/+) and B6(Cg)‐Grntm1.1Aidi/J (PGRN−/−) mice. …”
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Fodder qualities of heterotic hybrids from intergeneric crosses between maize and eastern gamagrass by P. A. Panikhin, V. A. Sokolov

“…Eastern gamagrass (Tripsacum dactyloides L.), a wild relative of maize, is widespread over the plains of North and South Americas. …”
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Reconstructing the experienced temperature during the larval oceanic migration of anguillid eels from otolith stable oxygen isotopes by Mari Kuroki, Shunsuke Hayasaka, Kozue Nishida, Toyoho Ishimura, Akihiro Okamura, Yoshiaki Yamada, Yu-San Han, Kotaro Shirai

“…Subsequently, the obtained equation between water temperature and δ18Ootolith was applied to estimate the water temperature experienced by wild-caught glass eels during their larval oceanic migration according to recruitment latitude, season, and species. …”
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Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo by Soyeon Hong, Hee Ju Lee, Da Seul Jung, Saruul Erdenebileg, Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon, Gyhye Yoo

“…<i>Cotoneaster wilsonii</i> Nakai, an endemic species of the Korean Peninsula, grows wild in Ulleungdo. In this study, we aimed to investigate the effects of <i>C. wilsonii</i> and its components on osteoporosis. …”
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