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1901
Interplay of aurora kinase a functional residues and Epstein-barr Nuclear Antigen 1 in Epstein-barr virus associated Gastric cancer using AGS cells
Published 2025-01-01“…Further, EBNA1, the latent gene of EBV, stabilises the AURKA in its wild-type form and S89A mutant but unable to stabilise in T287/288A double mutant. …”
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1902
A Protein with Unknown Function, Ps495620, Is Critical for the Sporulation and Oospore Production of <i>Phytophthora sojae</i>
Published 2024-12-01“…The <i>Ps495620</i>-knockout mutants exhibited significantly increased oospore production and decreased sporangium formation compared to the wild-type strain P6497. Transcriptomics showed that it is a key regulator of nitrogen, pyruvate, ascorbate, and adorate metabolism in <i>P. sojae</i>. …”
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1903
High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
Published 2025-01-01“…All but two strains were significantly different from wild-type controls in at least one feature. The observed phenotypes were diverse, but mutations of genes predicted to have related functions led to similar behavioural differences in worms. …”
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1904
The mammal fauna of the city of Luhansk (Ukraine) in the pre-war period (2004–2014)
Published 2024-12-01“…The urban mammal fauna of Luhansk is characterised by a high proportion of wild species, which is facilitated by the significant dismemberment of the city by a ravine system and the river valley, as well as the presence of large little-transformed areas that was formed due to the development of the city using a modular system (residential quarters) and large areas of private estate-type housing, as well as a number of summer cottages and recreational areas that are part of the city. …”
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1905
Bioactive compounds in the aboveground part of hemiephemeroid onions (Allium L.)
Published 2020-12-01“…Earlier, we investigated the aboveground organs of a number of wild onion species in the consumer ripeness phase. …”
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1906
Vimentin-Rab7a Pathway Mediates the Migration of MSCs and Lead to Therapeutic Effects on ARDS
Published 2021-01-01“…As a result, we found that MSCs from wild-type mice can significantly alleviate ARDS and reduce lung inflammation, while vimentin gene knockout reduced the therapeutic effect of MSCs in ARDS. …”
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1907
Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β
Published 2016-01-01“…To determine whether meprin B cleaves OS-9 in vivo, wild-type (WT) and meprin αβKO mice were subjected to IR-induced renal injury. …”
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1908
Physiological and transcriptome analysis of sex-specific responses to cadmium stress in poplars
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1909
IncF Plasmids Are Commonly Carried by Antibiotic Resistant Escherichia coli Isolated from Drinking Water Sources in Northern Tanzania
Published 2016-01-01“…Detection of these public health-relevant conjugative plasmids and antibiotic resistant traits in Tanzanian water suggests the possible pollution of these water sources from human, livestock, and wild animal wastes and also shows the potential of these water sources in the maintenance and transmission of these resistance traits between environments, animals, and people.…”
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1910
Identifying novel heterozygous PI4KA variants in fetal abnormalities
Published 2025-01-01“…The effects of the identified variants on splicing were analyzed through minigene splicing assays. Subsequently, both wild-type and mutant PI4KA protein fragments were purified, and their enzymatic activities were quantitatively assessed. …”
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1911
Exposure to Lead (Pb) influences the outcomes of male-male competition during precopulatory intrasexual selection
Published 2024-10-01“…Assessment of a range of locations in the wild found a consistent pattern of metal-associated size declines in more contaminated locations for males, but not for females.…”
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1912
Nomenclatural standards for the spring oat cultivars (<i>Avena sativa</i> L.) developed in the Urals and Siberia
Published 2025-01-01“…The items are deposited in the Herbarium of Cultivated Plants of the World, Their Wild Relatives and Weeds (WIR), and are made part of the collections of the National Center for Plant Genetic Resources. …”
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1913
Mineral composition of bread wheat lines with introgressions of alien genetic material
Published 2023-04-01“…Modern bread wheat (Triticum aestivum L.) cultivars developed mainly to increase productivity often contain low concentrations of minerals in their grain. Wild and primitive wheats demonstrate rich genetic diversity, including the content of minerals in the grain, and can be used to improve the wheat gene pool for this trait. …”
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1914
Deletion of the waaf gene affects O antigen synthesis and pathogenicity in Vibrio parahaemolyticus from shellfish
Published 2022-03-01“…Thus, we constructed a waaf gene deletion mutant (i.e., △waaf) of wild-type (WT) which isolated from shellfish serotype O3:K6 via chitin-mediated transformation technology. …”
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1915
Scientific justification of Mycobacterium avium survival in natural environment of Republic of Dagestan
Published 2024-03-01“…Mycobacterium avium can grow and replicate in organic wastes from the poultry farms for a long time thus contaminating vast adjacent areas and being the source of infection not only for wild and domestic animals but also for humans. The studies were aimed at the examination of the duration of Mycobacterium avium survival in the natural environment in two geographical regions of the Republic of Dagestan characterized by different soil and climate. …”
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1916
Intraspecific diversity of durum wheat (Triticum durum Desf.): a unif ied classif ication
Published 2021-06-01“…This is the world’s first standardized system that contains all known intraspecific (infraspecific) taxa of wild and cultivated wheat species. A detailed classification makes it possible to identify a wide variety of forms in the genus Triticum L. and its individual species, which is especially important for collections preserved in genetic seed banks. …”
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1917
Signatures of selection and candidate genes for adaptation to extreme environmental factors in the genomes of Turano-Mongolian cattle breeds
Published 2021-04-01“…The authors conclude that the current literature data do not provide preference to one of the two possible scenarios of Turano-Mongolian breed origins: as a result of the domestication of a wild aurochs at East Asia or as a result of the migration of taurine proto-population from the Middle East. …”
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1918
Comprehensive genome-wide analysis of ARF transcription factors in orchardgrass (Dactylis glomerata): the positive regulatory role of DgARF7 in drought resistance
Published 2025-02-01“…Overexpressed Arabidopsis lines of DgARF7 exhibited a markedly higher relative water content and superoxide dismutase activity, while the malondialdehyde content was significantly decreased compared to wild type under drought stress. DgARF7 also accelerated flowering time by inducing the flowering-related gene expression levels in Arabidopsis. …”
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1919
Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Published 2018-01-01“…The accumulation of N-Hcy in hair keratin led to a progressive reduction of N-Hcy-keratin solubility in sodium dodecyl sulfate, from 0.39 ± 0.04 in wild-type mice to 0.19 ± 0.03, 0.14 ± 0.01, and 0.07 ± 0.03 in Mthfr−/−, Cse−/−, or Cbs−/−animals, respectively. …”
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1920
SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation
Published 2025-02-01“…Furthermore, SOCS2 associated and inhibited the activation of KIT mutations, but not wild-type KIT, in addition to its inhibition of GHR signaling, suggesting that KIT mutations may promote their activation by downregulation of SOCS2 expression. …”
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