Metabolic Context Regulates Distinct Hypothalamic Transcriptional Responses to Antiaging Interventions by Alexis M. Stranahan, Bronwen Martin, Wayne Chadwick, Sung-Soo Park, Liyun Wang, Kevin G. Becker, William H. WoodIII, Yongqing Zhang, Stuart Maudsley

“…In this paper, we investigated the effects of two well-characterized antiaging interventions, caloric restriction and voluntary wheel running, in two distinct physiological paradigms, that is, diabetic (db/db) and nondiabetic wild-type (C57/Bl/6) animals to investigate the contextual sensitivity of hypothalamic transcriptomic responses. …”
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Alpha synuclein overexpression can drive microbiome dysbiosis in mice by Timothy R. Sampson, Zachary D Wallen, Woong-Jai Won, David G. Standaert, Haydeh Payami, Ashley S. Harms

“…Here, we used a transgenic mouse strain, which overexpress wild-type human α-syn to test how the gut microbiome composition responds in this model of PD pathology during aging. …”
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Exenatide Is an Effective Antihyperglycaemic Agent in a Mouse Model of Wolfram Syndrome 1 by Tuuli Sedman, Kertu Rünkorg, Maarja Krass, Hendrik Luuk, Mario Plaas, Eero Vasar, Vallo Volke

“…Exenatide in a dose of 10 μg/kg lowered the blood glucose level in both wild-type and wolframin-deficient mice when administered during a nonfasted state and during the intraperitoneal glucose tolerance test. …”
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Arabidopsis apoplast TET8 positively correlates to leaf senescence, and tet3tet8 double mutants are delayed in leaf senescence by Jayde A. Zimmerman, Benjamin Verboonen, Andrew P. Harrison Hanson, Luis R. Arballo, Judy A. Brusslan

“…We observed that TET8 is more abundant in the apoplast of early senescing pen1 and pen1pen3 mutant rosettes and in older wild‐type (WT) rosettes. The increase in apoplast TET8 in the pen1 mutant did not correspond to increased TET8 mRNA levels. …”
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Enhanced multivariate data fusion and optimized algorithm for comprehensive quality profiling and origin traceability of Chinese jujube by Peng Chen, Xiaoli Wang, Rao Fu, Xiaoyan Xiao, Yu Li, Tulin Lu, Tao Wang, Qiaosheng Guo, Peina Zhou, Chenghao Fei

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Transcranial Direct Current Stimulation Modulates Neurogenesis and Microglia Activation in the Mouse Brain by Anton Pikhovych, Nina Paloma Stolberg, Lea Jessica Flitsch, Helene Luise Walter, Rudolf Graf, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger

“…Here we studied the effects of tDCS on microglia activation and neurogenesis in the mouse brain. Male wild-type mice were subjected to multisession tDCS of either anodal or cathodal polarity; sham-stimulated mice served as control. …”
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Altered Macrophage and Dendritic Cell Response in Mif−/− Mice Reveals a Role of Mif for Inflammatory-Th1 Response in Type 1 Diabetes by Yuriko Itzel Sánchez-Zamora, Imelda Juarez-Avelar, Alicia Vazquez-Mendoza, Marcia Hiriart, Miriam Rodriguez-Sosa

“…To address this issue, we induced T1DM by administering multiple low doses of streptozotocin (STZ) to Mif−/− or wild-type (Wt) BALB/c mice. We found that Mif−/− mice treated with STZ (Mif−/−STZ) developed lower levels of hyperglycemia, inflammatory cytokines, and specific pancreatic islet antigen- (PIAg-) IgG and displayed reduced cellular infiltration into the pancreatic islets compared to Wt mice treated with STZ (WtSTZ). …”
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The effects of runs-of-homozygosity on pig domestication and breeding by Lin Tao, Hang Liu, Adeniyi C. Adeola, Hai-Bing Xie, Shu-Tang Feng, Ya-Ping Zhang

“…Results Here we integrated a comprehensive dataset comprising 7239 domesticated pigs and wild boars genotyped by single nucleotide polymorphism (SNP) chips, along with phenotypic data encompassing growth, reproduction and disease-associated traits. …”
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Spatiotemporal variability and functional redundancy obscure effects of urbanization on strawberry pollinators by Kyla D. Schulte, Caleb J. Wilson, Anna Tawril, Mary A. Jamieson

“…Our study demonstrates the importance of wild bees, especially native species, as pollinators in urban agriculture and illustrates how habitat context shapes bee communities.…”
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Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study. by Md Mostafa Kamal, Kazi Fahmida Haque Shantanu, Shamiha Tabassum Teeya, Md Motiar Rahman, A K M Munzurul Hasan, Douglas P Chivers, Tanveer A Wani, Atekah Hazzaa Alshammari, Mahesh Rachamalla, Francisco Carlos da Silva Junior, Md Munnaf Hossen

“…Finally, MD simulation revealed consistent fluctuation in RMSD and RMSF, consequently Rg, hydrogen bonds, and PCA in the mutant proteins compared with wild-type, which might alter the functional and structural stability of CTLA4 protein. …”
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Ecoepidemiology of Chagas Disease in a Biological Corridor in Southeastern Mexico: A Promising Approach to Understand the Risk of Chagas Disease by Ingrid Yazmin Cruz-Alegría, Nancy Gabriela Santos-Hernández, Christian Ruiz-Castillejos, Juan Felipe Ruan-Soto, Adriana Moreno-Rodríguez, Any Laura Flores-Villegas, Javier Gutiérrez-Jiménez, Luis Arturo Hernández-Mijangos, Eduardo Estanislao Espinoza-Medinilla, Dolores Guadalupe Vidal-López, José Antonio De Fuentes-Vicente

“…Temperature and humidity were not determining factors for the probability of insect capture. Of the 108 wild mammals (Chiroptera, Rodentia, and Didelphimorphia), none was infected with T. cruzi. …”
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Crimean-Ottoman Factor in the Socio-Cultural System of Russia in Early Modern Times by T. V. Chernikova

“…But the transfer of the agrarian center to the south was restrained by the constant military danger from the Wild Field, which was part of the Horde, and then the Crimean Khanate, backed until the end of the 18 century by the Ottoman Empire, perceiving the Black Sea with its “inland lake”. …”
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Analysis of the VERNALIZATION-A1 exon-4 polymorphism in polyploid wheat by A. F. Muterko, E. A. Salina

“…With the exception of one accession, the mutant type of exon-4 was identified only in combination with the wild type. Furthermore, allele-specific primers were designed to identify the VRN-D4 gene or in order to exclude its impact on the results during analysis of the VRN-A1 haplotypes. …”
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Genetic diversity and differentiation of cultured Nile tilapia populations from Ethiopia revealed by ddRAD-seq: implications for better hatchery management by Geletu Temesgen Tola, Tang Shoujie, Zhao Jinliang

“…Nile tilapia aquaculture in Ethiopia is dominated by small-scale fish farming in ponds, with seeds from poorly managed hatcheries and wild sources. Hence, the development of aquaculture in Ethiopia faces a major hurdle owing to the absence of good-quality seeds, largely because of the lack of genetic management practices within hatchery centers. …”
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Chemical composition and antimicrobial activity of Artemisia annua (L.) essential oil against different fish pathogens by F. Sakhaie, M. Adel, R. Safari, F. Firouzbakhsh, A. Nosrati Movafagh, T. Stadtlander

“…In the present study, the composition of the essential oil and antimicrobial activity from aerial parts of Artemisia annua growing wild in north of Iran was investigated. The major ingredients of the essen-tial oil of A. annua were camphor (29.2%), 1.8-cineole (13.3%), tetradecanol (6.16%), β-selinene (5.82%) and pinocarvone (3.86%). …”

Farmer’s Knowledge on Thaumatotibia Leucotreta (Meyrick) an Economic Pest of Avocado Production in Tanzania by Juliana G. Shikoshi, Angela G. Mkindi, Patrick A. Ndakidemi, Ernest R. Mbega, Kelvin M. Mtei

“…Thaumatotibia leucotreta (Meyrick) is a Lepidopteran pest that feeds on more than 70 plant species, both wild and cultivated. A study was carried out in Tanzania to assess farmer’s knowledge regarding the invasion of pests in avocado fruit production in Tanzania. …”
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Effects of limited introgressions from Triticum timopheevii Tausch. into the genome of bread wheat (Triticum aestivum L.) on physiological and biochemical traits under normal water... by T. A. Pshenichnikova, A. V. Permyakov, S. V. Osipova, M. D. Permyakova, E. G. Rudikovskaya, V. V. Verchoturov

“…Alien hybridization in cereals is used for comparative investigations of genome structure and evolution as well as for extracting useful genes from the wild gene pool. The tetraploid species Triticum timopheevii has long been used as a source of genes for resistance to fungal diseases. …”
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Evidence of avian and human influenza A virus infection in farmed Siamese crocodiles (Crocodylus siamensis) in Thailand. by Metawee Thongdee, Somjit Chaiwattanarungruengpaisan, Natthaphat Ketchim, Nareerat Sangkachai, Nlin Arya, Wanna Sirimanapong, Witthawat Wiriyarat, Pilaipan Puthavathana, Weena Paungpin

“…In addition, we demonstrated the ability of wild-type IAV subtypes (H1, H2, H9 and human H1) to infect primary Siamese crocodile fibroblast cells. …”
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Elucidating the Prognostic Role of BRAFV600E and the Activation Status of the Downstream MAPK Pathway in PTC: A Study from a Tertiary Centre in India by Nadeem Kocheri, Priti Chatterjee, Shipra Agarwal, Mehar C. Sharma, Sanjana Ballal, Chandrasekhar Bal, Sunil Chumber

“…All the non-PTC cases were BRAF-wild type, but 20% showed weak immunopositivity for mutated protein and were scored 6. …”
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Cathepsin K Deficiency Impaired Ischemia-Induced Neovascularization in Aged Mice by Xueling Yue, Haiying Jiang, Ying Xu, Manli Xia, Xian-Wu Cheng

“…To study the putative role of CatK in ischemia-induced angiogenesis, we applied a hindlimb ischemia model to aged wild-type (CatK+/+) and CatK-deficient (CatK−/−) mice. …”
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