Characterization of a Novel Tc-Carbonyl Complex as a Functional Probe of P-Glycoprotein Transport Activity by Mary Dyszlewski, Helen M. Blake, Julie L. Dahlheimer, Christina M. Pica, David Piwnica-Worms

“…Biodistribution analysis following tail vein injection of Tc-CO-MIBI showed delayed liver clearance as well as enhanced brain uptake and retention in mdr1a/1b (−/−) gene deleted mice versus wild-type mice, directly demonstrating that Tc-CO-MIBI is a functional probe of Pgp transport activity in vivo.…”
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ANTHRAX GLOBAL EPIZOOTOLOGY. 2. DISEASE INCIDENCE IN HUMANS AS INDICATOR OF EPIZOOTIC AND RISK FACTORS by V. V. Makarov, N. Ya. Makhamat

“…Consumption of infected products from domestic (up to 70%) and wild animals prevails among the trivial risk factors of zoonogenous infection in humans, while consumption of meat from domestic animals and contacts with diseased animals prevail among the lethality risk factors. …”
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Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway. by Yael Litvak, Shir Sharon, Meirav Hyams, Li Zhang, Simi Kobi, Naama Katsowich, Shira Dishon, Gabriel Nussbaum, Na Dong, Feng Shao, Ilan Rosenshine

“…Importantly, upon infection with wild type EPEC this NF-κB activation is antagonized by anti-NF-κB effectors, including NleB, NleC and NleE. …”
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Short Shoot Growth and Reproduction Response to Light Conditions Vary with Order Branching in the Proximal Part of C. atlantica Crown by Fatima-Ezzahra Saouab, Mohammed Bendriss Amraoui

“…This study compared the effects of shading in individual branch orders 2 and 3 on the needle survival, growth, and reproduction of five categories of short shoots of the proximal part of wild Atlas cedar (Cedrus atlantica (Endl.) G. Manetti ex Carrière). …”
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The study of agronomical traits determining productivity of Triticum aestivum/Triticum timopheevii introgression lines with resistance to fungal diseases by I. N. Leonova, E. B. Budashkina

“…Development of resistant cultivars is one of the effective ways for protection of common wheat T. aestivum L. from fungal pathogens. The gene pool of wild and cultivated wheat relatives is often used for widening the wheat genetic diversity of resistance genes. …”
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Effect of a high-fat diet and iron overload on erythropoiesis in mice by Joe Varghese, Jithu James Varghese, Molly Jacob

“…Methodology: Male C57Bl/6J wild-type (WT) mice were fed a high-fat diet (HFD) (to produce hyperinsulinemia) or a control diet (CD) for varying periods (4–24 weeks). …”
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The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response by Thomas Daniel Kraemer, Orlando Daniel Quintanar Haro, Eugen Domann, Trinad Chakraborty, Svetlin Tchatalbachev

“…Infection of mouse RAW264.7 macrophages with a tcpF knock-out mutant led to elevated cytokine response compared to the isogenic wild type E. faecalis strain. In silico analysis predicted significant tertiary structure homology to the TIR domain of human TLR1 (TLR1-TIR). …”
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Altered olfactory responses in Fmr1 KO mice by Jan Tuma, Amtul-Noor Rana, Teena Philip, Jeong Ben Park, Hye Young Lee

“…Here, we found that Fmr1 knock-out (KO) mice, a mouse model of FXS, showed increased sniffing duration for non-social odors during their first exposure. Additionally, while wild-type (WT) males demonstrated differences in behavioral patterns between non-social odors while Fmr1 KO males did not show such distinction. …”
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A Ralstonia solanacearum type III effector alters the actin and microtubule cytoskeleton to promote bacterial virulence in plants. by Rachel Hiles, Abigail Rogers, Namrata Jaiswal, Weiwei Zhang, Jules Butchacas, Marcus V Merfa, Taylor Klass, Pragya Barua, Venkatesh P Thirumalaikumar, Jonathan M Jacobs, Christopher J Staiger, Matthew Helm, Anjali S Iyer-Pascuzzi

“…Importantly, tomato plants inoculated with R. solanacearum K60 lacking RipUK60 (ΔripUK60) had reduced wilting symptoms and significantly reduced root colonization when compared to plants inoculated with wild-type R. solanacearum K60. Collectively, our data suggest that R. solanacearum K60 uses the type III effector RipUK60 to remodel cytoskeletal organization, thereby promoting pathogen virulence.…”
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Organophosphorus Nerve Agents: Types, Toxicity, and Treatments by Sudisha Mukherjee, Rinkoo Devi Gupta

“…The current research on the promising treatments specifically the catalytic bioscavengers including several wild-type organophosphate hydrolases such as paraoxonase and phosphotriesterase, phosphotriesterase-like lactonase, methyl parathion hydrolase, organophosphate acid anhydrolase, diisopropyl fluorophosphatase, human triphosphate nucleotidohydrolase, and senescence marker protein has been widely discussed. …”
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Delineating the environmental justice implications of an experimental cheetah introduction project in India by Yashendu C. Joshi, Stephanie E. Klarmann, Stephanie E. Klarmann, Louise C. de Waal

“…In this perspective piece, we use Project Cheetah as a case study to exemplify broader issues applicable to rewilding and restoration projects that necessitate attention by proponents and authorities responsible for issuing the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) import and export permits.…”
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Hooded crows (Corvus cornix) manufacture objects relative to a mental template by Anna A. Smirnova, Leia R. Bulgakova, Maria A. Cheplakova, Sarah A. Jelbert

“…Therefore, we found the ability to manufacture physical objects relative to a mental template in yet another bird species not specialized in using or making foraging tools in the wild, but with a high level of brain and cognitive development.…”
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Analysis of the Progress in Identification and Evaluation of Laboratory Animal Resources in China by DU Xiaoyan, LIU Yunbo

“…This paper first discusses the significance of identifying and evaluating laboratory animal resources, summarizes three new approaches to developing these resources, including the domestication and standardization of laboratory animals (economic, ornamental, agricultural, and wild animals, etc.), the acquisition of new strains (species) through natural mutation and induced mutation, and the creation of new laboratory animal resources through gene editing technology. …”
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Savoirs paysans autour des huiles d’olive, (zaytun, Olea europaea var. europaea) et d’oléastre, (əl-bərri, Olea europaea var. sylvestris) Rif, nord du Maroc by Yildiz Aumeeruddy-Thomas, Dominique Caubet

“…The joint ethnobotanic and linguistic joint approach, through the analysis of certain terms such as məslāl used to describe a type of wild olive oil, zitəl bərri məslāl, shows a binary classification of varieties of oils, which could have led to the selection of varieties of the same name spreading mostly in the North of Morocco. …”
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A first exploratory comparison of the behaviour of wolves (Canis lupus) and wolf-dog hybrids in captivity by Federica Amici, Simone Meacci, Emmeline Caray, Linda Oña, Katja Liebal, Paolo Ciucci

“…Abstract Extensive introgression of genes from domesticated taxa may be a serious threat for the genomic integrity and adaptability of wild populations. Grey wolves (Canis lupus) are especially vulnerable to this phenomenon, but there are no studies yet assessing the potential behavioural effects of dog-introgression in wolves. …”
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The Populus MYB transcription factor PSAR1 negatively regulates salt stress and is a repressor of ABA signaling by Qing Fang, Caiyun Zhang, Jingjie Liu, Zhi Zeng, Yanke Lu

“…A markedly diminished tolerance to salt stress was observed in the engineered Arabidopsis overexpressing PSAR1 (OeLAs) compared with Wt (wild-type) plants. OeLAs seed germination to ABA (1.0 μM) was less sensitive. …”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…Further focused screening revealed the K187T variant, which exhibited a fourfold increase in catalytic efficiency (k cat /K M ) over wild-type ACE2. Conclusions This work demonstrates the potential of droplet microfluidics for therapeutic peptidase engineering, offering a robust and accessible method to optimize enzyme properties for clinical applications.…”
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Androgenic response of Triticum durum-Dasypyrum villosum amphidiploids and their parental forms by H. Stoyanov, I. Belchev

“…One of the most valuable species with regard to the possibilities for introducing valuable traits and properties into wheat species is the wild Dasypyrum villosum. With the aim to study the androgenic response of the Triticum durum-D. villosum amphidiploids, two accessions and their parental forms – the durum wheat cultivars Gergana and Argonavt and a landrace of the D. villosum – were studied. …”
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Tilapia Lake Virus (TiLV): a Globally Emerging Threat to Tilapia Aquaculture by Lowia Al-Hussinee, Kuttichantran Subramaniam, Win Surachetpong, Vsevolod Popov, Kathleen Hartman, Katharine Starzel, Roy Yanong, Craig Watson, Hugh Ferguson, Salvatore Frasca Jr, Thomas Waltzek

“…., and Thomas Waltzek and published by the UF/IFAS School of Forest Resources and Conservation, Program in Fisheries and Aquatic Sciences describes this important emerging disease and explains how to prevent outbreaks and what to do if you suspect TiLV in an aquaculture facility or in the wild.  http://edis.ifas.ufl.edu/fa213 …”
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Determination of the effect of GA3 applications on plant development, nutrient content change and analysis of root architectural features using ML artificial neural network modelli... by Sari Ömer

“…This study has determined the effects of gibberallic acid (GA3) on the plant development, root and bulb nutrient content in the wild species Tulipa saxatilis. Spray treatments of GA3 at 0, 100, 200 and 400 ppm wereconducted in research. 400 ppm is the most effective application, which increased plant height and flower stem length by 39% and 35.6%, respectively. …”
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