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1361
From Prion Diseases to Prion-Like Propagation Mechanisms of Neurodegenerative Diseases
Published 2013-01-01“…In animals, the most frequent prion diseases are scrapie in sheep and goat, bovine spongiform encephalopathy in cattle, and the emerging chronic wasting disease in wild and captive deer in North America. The hallmark of prion diseases is the deposition in the brain of PrPSc, an abnormal β-sheet-rich form of the cellular prion protein (PrPC) (Prusiner 1982). …”
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1362
African swine fever: one hundred years later
Published 2022-06-01“…Gap analysis carried out by the large team of the European researchers and experts revealed the most challenging aspects – wild boars, ASF survival and transmission, biosecurity and surveillance. …”
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1363
Reliable detection of doppelgängers based on deep face representations
Published 2022-05-01“…In this work, the impact of doppelgängers on the HDA Doppelgänger and Disguised Faces in The Wild databases is assessed using a state‐of‐the‐art face recognition system. …”
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1364
Cell-free assays reveal that the HIV-1 capsid protects reverse transcripts from cGAS immune sensing.
Published 2025-01-01“…To study this process in mechanistic detail, we reconstituted reverse transcription, genome release, and innate immune sensing of HIV-1 in a cell-free system. We found that wild-type HIV-1 capsids protect viral genomes from cGAS even after completing reverse transcription. …”
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1365
Isolation of MDCK cells with low expression of mdr1 gene and their use in membrane permeability screening
Published 2022-06-01“…It contains endogenous transporters, most prominently canine multidrug resistance P-glycoprotein (Mdr1), which can interfere with studies of P-glycoprotein substrate assessment and permeability measurements. Because MDCK wild type (WT) is genetically heterogeneous, an isolation procedure was investigated in this study to obtain the subclonal line with low P-glycoprotein expression. …”
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1366
Models for the spread and persistence of hantavirus infection in rodents with direct and indirect transmission
Published 2009-12-01“…Hantavirus, a zoonotic disease carried by wild rodents, is spread among rodents via direct contact and indirectly via infected rodent excreta in the soil. …”
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1367
Tracking the Economic Benefits Generated by the Hard Clam Aquaculture Industry in Florida
Published 2014-10-01“…From a cottage industry borne of reductions in commercial wild clam harvests in the Indian River Lagoon during the late 1980s, hard clam aquaculture has now developed into an industry that is rivaled by no other aquaculture food product in Florida. …”
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1368
Trade-Off between Sampling Frequency and Duration and Their Influences on the Estimation of Space Use of Japanese Macaques
Published 2023-01-01“…Space use, estimated based on location data, provides fundamental knowledge in the basic and applied ecology of wild animals. There is a trade-off between sampling frequency and duration in location data which are collected from a tracking device attached to an animal because the battery of the device has a limited life. …”
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1369
La mise en art de la Blackfoot Valley (Montana, USA) ou comment (ré) concilier le front minier et le front écologique ?
Published 2017-06-01“…An entirely private, site-specific art project (Blackfoot Pathways: Sculpture in the Wild) creates the possibility of offering an alternative resource to be shared by eco-gentrifiers and a local population adjusting to a post-extractive order, and indeed its site-specific works resonate with both the valley’s mining past and its untamed nature. …”
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1370
Climatic, Regional Land-Use Intensity, Landscape, and Local Variables Predicting Best the Occurrence and Distribution of Bee Community Diversity in Various Farmland Habitats in Uga...
Published 2013-01-01“…Bee abundance and species richness increased significantly () with increase in percent cover of semi-natural habitats and the abundance of wild and cultivated floral resources in the landscape. …”
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1371
EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer
Published 2025-02-01“…A triple therapy regimen of Remodelin, cetuximab, and 5-Fu showed potential as a treatment strategy for CRC with wild-type KRAS, NRAS and BRAF.…”
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1372
The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium
Published 2025-02-01“…HOCl is a powerful microbicide widely used for sanitization in industrial settings. We used wild-type S. Typhimurium and the mutant lacking the arcB gene exposed to NaOCl to describe the global transcriptional response. …”
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1373
Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy
Published 2025-02-01“…To further improve efficacy, we explored AAV-mediated delivery of the soluble PD-L1 (sPD-L1) to CIA mice.ResultAfter intra-articular injection of AAV6 vectors expressing the optimal isoform of sPD-L1 (shPD-L1), more potency was observed when compared to wild type PD-L1, with a lower dose of AAV6/shPD-L1 needed for arthritis improvement. …”
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1374
Megagrazer loss drives complex landscape-scale biophysical cascades
Published 2025-01-01“…Wild animals can modulate ecosystem-climate feedbacks, e.g. through impacts on vegetation and associated carbon dynamics. …”
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1375
Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology
Published 2025-02-01“…Contrary to expectations, we report that wild-type B. burgdorferi B31 cells are radiosensitive, with a gamma-radiation survival limit for 106 wild-type cells of <1 kGy. …”
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1376
Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018
Published 2025-01-01“…We conclude on the importance to work with synergistic networks to assess infection spread in wild bird species, as well as the negative impact of an emerging arbovirus. …”
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1377
UPLC-HRESI-MS and GC-MS analysis of the leaves of Nicotiana glauca
Published 2022-03-01“…The alkaloid-rich fraction obtained by fractionation of the crude methanolic extract of the leaves of wild tobacco tree Nicotiana glauca Graham (Solanaceae) was analyzed using UPLC-MS and GC-MS. …”
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1378
Etude de l’alimentation du magot Macaca sylvanus dans le site touristique des cascades d’Ouzoud (Maroc)
Published 2017-02-01“…The flora contributing to diet of the study group includes 87 species of angiosperms and gymnosperms, from theses 52 species are wild plants and 35 are agricultural plants. Conservation effort of Barbary macaques should consider the inclusion of human food in the diet of groups living in tourist sites.…”
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1379
Cloning, Structural Characterization, and Phylogenetic Analysis of Flower MADS-Box Genes from Crocus (Crocus sativus L.)
Published 2007-01-01“…In order to uncover and understand the molecular mechanisms controlling flower development in cultivated crocus and its relative wild progenitor species, and characterize a number of crocus flower mutants, we have cloned and characterized different, full-length, cDNA sequences encoding MADS-box transcription factor proteins involved in flower formation.…”
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1380
Complex wolbachia infection dynamics in mosquitoes with imperfect maternal transmission
Published 2018-03-01“…In the last few years, a new disease control method, besides pesticide spraying to kill mosquitoes, has been developed by releasing mosquitoes carrying bacterium Wolbachia into the natural areas to infect the wild population of mosquitoes and block disease transmission. …”
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