Molecular Detection of <i>Rickettsia</i> spp. and Other Tick-Borne Pathogens in Ticks from a Nature Reserve: Implications for Zoonotic Transmission by Santina Di Bella, Valeria Blanda, Silvia Scibetta, Ilenia Giacchino, Antonino Gentile, Giuseppina Chiarenza, Vincenza Cannella, Giovanni Provinzano, Francesca Grippi, Annalisa Guercio

“…This study focused on ticks found in a nature reserve in southern Italy, highly frequented for recreational activities and inhabited by wild boars. Using molecular techniques, 214 ticks, including questing ticks and those removed from wild boars, were examined for tick-borne pathogens (TBPs), with a focus on zoonotic pathogens. …”
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P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion by Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Vanessa Figliuolo, Claudia Lucia Martins Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva

“…Our in vivo experiments also showed that intralesional UTP treatment reduced both parasite load (in the footpads and popliteal lymph nodes) and lesion size in wild-type (WT) and CASP-11−/− but not in CASP-1,11−/− mice. …”
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Comparative transcriptomics reveal stage-dependent parasitic adaptations in the myxozoan Sphaerospora molnari by Monika M. Wiśniewska, Jiří Kyslík, Gema Alama-Bermejo, Alena Lövy, Martin Kolísko, Astrid S. Holzer, Anush Kosakyan

“…Conclusions In order to address the threat posed by myxozoans to both cultured fish species and wild stocks, it is imperative to deepen our understanding of their genetics. …”
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General immunologic reactivity of patients with COVID-19 and its relation to gene polymorphism, severity of clinical course of the disease and combination with comorbidities by M.O. Sokolenko, L.P. Sydorchuk, L.S. Sokolenko, A.A. Sokolenko

“…The overall immunological reactivity of the body of patients with coronavirus infection increases in the presence of the wild-type T-allele of the eNOS gene (rs2070744) in the patient's genotype, especially the CC genotype, by 21.98-57.89% (p≤0.029-0.001), against the background of a decrease in the index of nonspecific reactivity and the ratio of agranulocytes to ESR – by 23.0 (p=0.039) and 15.74% (p=0.044), indicating the onset of specific immunological reactions in the active infectious process. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…The current study employed two transgenic wheat lines (MG1516 and MG1314) overexpressing the MGDG synthase gene (TaMGD) and wild-type cv ''JW1'' to explore the function of TaMGD in response to high temperature stress during the anthesis stage of wheat. …”
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Nutritional and medicinal characteristics of Chinese giant salamander (Andrias davidianus) for applications in healthcare industry by artificial cultivation: A review by Dong He, Wenming Zhu, Wen Zeng, Jun Lin, Yang Ji, Yi Wang, Chong Zhang, Yuan Lu, Daoquan Zhao, Nan Su, Xin-Hui Xing

“…Chinese giant salamander (CGS), is one of the largest and oldest amphibians existing in the world and is also one of the valuable biological resources of China. Wild CGS has been threatened with extinction in the past decades due to over capturing, deterioration of natural environment, the slow breeding and growth of the wild species in nature. …”
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NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

“…The therapeutic effects of transplanted wild-type EPC, Nlrp3 knockout EPC, and Nlrp3 overexpression EPC were evaluated. …”
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Bacterial blood microbiome of Mastomys rodents: implications for disease spill-over at the animal-human interface within the Bushbuckridge-East community, South Africa by Agatha O. Kolo, Agatha O. Kolo, Kelly A. Brayton, Kelly A. Brayton, Nicola E. Collins, Armanda D. S. Bastos, Armanda D. S. Bastos, Armanda D. S. Bastos, Sonja Matthee, Cory A. Gall, Jeanette Wentzel, Jeanette Wentzel, Luis Neves, Luis Neves, Marinda C. Oosthuizen

“…In this study we investigated bacterial diversity in wild and commensal rodents sampled from different habitats. …”
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NLRP3: a key regulator of skin wound healing and macrophage-fibroblast interactions in mice by Jiamin Zhao, Shuangyi Zhang, Zhiguo Gong, Wei Mao, Wenhui Bao, Qianru Li, Yunjie Bai, Feifei Gao, Shuang Feng

“…Similarly, conditioned media from wild-type M1 or M2 macrophages promoted the expression of FGF-2, VEGF, and MMP-2 expression in myofibroblasts, which was attenuated when using NLRP3−/− macrophage-conditioned media. …”
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A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability by Xiujuan Yang, Zhongzhi Gan, Xiaoling Guo, Xiang Huang, Juan Liu, Yingchun Zheng, Xiaoqiang Zhou, Jingli Lian, Yue Liu, Tingting Yang, Chao Li, Fenying Chen, Fei He, Xiangmin Xu, Yasi Zhou, Qian Liu, Xingkun Yang, Fu Xiong

“…Functional assays demonstrated that mutant cells exhibited increased levels of SOX5 mRNA and protein relative to wild-type cells, accompanied by enhanced protein stability. …”
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Prix versus quantités : les contorsions du marché du carbone européen by Nathalie Berta

“…Furthermore, since this market is above all a financial market driven by derivatives, achieving price stability through ex post supply adjustments is a wild hope. Only a tax could provide the expected price stability.…”
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How the BRAF V600E Mutation Defines a Distinct Subgroup of Colorectal Cancer: Molecular and Clinical Implications by Catherine E. Bond, Vicki L. J. Whitehall

“…Recent studies have found that they have clinical and molecular features of both the BRAF mutant/MSI and the conventional BRAF wild-type cancers and comprise a distinct colorectal cancer subgroup. …”
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Natural Area Weeds: Mexican Petunia (Ruellia simplex) by Sandra B. Wilson, Adrienne Burkhead, Carrie Reinhardt Adams, Rosanna Freyre, Alison M. Fox, Randall Stocker

“…Ruellia simplex (Mexican bluebell, Mexican petunia, or Britton's wild petunia) is an herbaceous perennial (USDA Hardiness Zone 8–11) in the family Acanthaceae. …”
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Nie tylko pies. Świat zwierzęcy w powieści i serialu „Czterej pancerni i pies” by Paweł Kaczyński

“…The same principle applies to wild animals — killing them provides one with food and clothing, but it is also shown as a test of manhood, as well as a skill that is most useful for a prospective soldier. …”
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Leptospirosis: An Unusual Cause of ARDS by Marc Clavel, Gwenaelle Lhéritier, Nicolas Weinbreck, Antoine Guerlin, Anthony Dugard, Eric Denes, Philippe Vignon

“…The diagnosis was retrospective when the niece of the patient presented with similar inaugural symptoms ten days later after being scratched by a wild rat which was considered by our patient as a pet.…”
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Role of Apolipoprotein E in Anxiety by Jacob Raber

“…In addition, human apoE isoforms have differential effects on anxiety in adult mice lacking apoE and probable AD patients. Compared to wild-type mice, mice lacking apoE and apoE4 mice showed pathological alterations in the central nucleus of the amygdala, which is involved in regulation of anxiety. …”
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PPARα as a Transcriptional Regulator for Detoxification of Plant Diet-Derived Unfavorable Compounds by Bunichiro Ashibe, Yu Nakajima, Yuka Fukui, Kiyoto Motojima

“…Feeding mice with various plant seeds and grains showed unexpected result that only sesame killed PPARα-null mice but not wild-type mice at all. A detailed analysis of this observation revealed that PPARα is involved in the metabolism of toxic compounds from plants as well as endobiotic substrates by inducing phase I and phase II detoxification enzymes. …”
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Effect of Culture Media on the Yield and Protein Content of Pleurotus ostreatus (Jacq.) Kumm Mycelia by Kayise Hypercia Maseko, Thierry Regnier, Obiro Cuthbert Wokadala, Paul Bartels, Belinda Meiring

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Vectors, Hosts, and the Possible Risk Factors Associated with Severe Fever with Thrombocytopenia Syndrome by Jin-Na Wang, Tian-Qi Li, Qin-Mei Liu, Yu-Yan Wu, Ming-Yu Luo, Zhen-Yu Gong

“…In particular, ticks have been implicated as vectors of SFTSV, where domestic or wild animals may play as the amplifying hosts. Many studies have identified antigens and antibodies against SFTSV in various animals such as sheep, goats, cattle, and rodents. …”
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Current Perspectives on Mycobacterium farcinogenes and Mycobacterium senegalense, the Causal Agents of Bovine Farcy by Mohamed E. Hamid

“…The zoonotic potentials of M. farcinogenes and M. senegalense are unknown; few studies reported the isolation of M. senegalense and M. farcinogenes from human clinical sources but not from environmental sources or from other domestic or wild animals.…”
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