Global proteomics and affinity mass spectrometry analysis of human Schwann cells indicates that variation in and loss of neurofibromin (NF1) alters protein expression and cellular... by Christian X Fay, Elizabeth R.M. Zunica, Elias Awad, William Bradley, Cameron Church, Jian Liu, Hui Liu, David K. Crossman, James A. Mobley, John P. Kirwan, Christopher L. Axelrod, Erik Westin, Robert A. Kesterson, Deeann Wallis

“…We used Strep tagged mNf1 cDNAs (both wild type (WT) and variant) to affinity purity NF1 Protein-Protein interactors (PPIs) from the Schwann cells. …”
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Breeding value of prolific maize varieties with nicking of parental lines by E. B. Khatefov, R. A. Kudaev, R. S. Kushkhova

“…Among the genetic reserves of the multiple-ear feature in maize are its wild relatives, such as teosinte (Zea mays L. subsp. mexicana (Schrad.) …”
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Achievements and prospects of applying high-throughput sequencing techniques to potato genetics and breeding by I. V. Bykova, N. A. Shmakov, D. A. Afonnikov, A. V. Kochetov, E. K. Khlestkina

“…Sequencing of the genome as well as transcriptomes and microRNomes of cultivated potato and its wild relatives, on one hand, is of fundamental interest, assisting in detecting features of genome evolution, ontogenetic development and mechanisms of various environmental stresses responses. …”
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Association between P2X7 Receptor Polymorphisms and Bone Status in Mice by Susanne Syberg, Peter Schwarz, Solveig Petersen, Thomas H. Steinberg, Jens-Erik Beck Jensen, Jenni Teilmann, Niklas Rye Jørgensen

“…By sequencing the most common strains of inbred mice, we found that only a few strains (BALB, NOD, NZW, and 129) were harboring the wild allelic version of the mutation (P451) in the gene for the purinergic receptor P2X7. …”
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Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice by Takefumi Kimura, Takero Nakajima, Yuji Kamijo, Naoki Tanaka, Lixuan Wang, Atsushi Hara, Eiko Sugiyama, Eiji Tanaka, Frank J. Gonzalez, Toshifumi Aoyama

“…In this study, sulfatide levels and the expression of enzymes related to sulfatide metabolism were examined using wild-type (+/+), Ppara-heterozygous (+/−), and Ppara-null (−/−) mice given a control diet or one containing 0.1% fenofibrate, a clinically used hypolipidemic drug and PPARα activator. …”
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Dynamic changes of extracellular vesicles during zebrafish organogenesis by Linda-Marie Mulzer, Tim Felger, Luis E. Muñoz, Gesa Engl, Heiko Reutter, Mario Schiffer, Leila Pourtalebi Jahromi, Fanni Annamária Boros, Friederike Zunke, Philipp Arnold, Alina C. Hilger

“…This study investigates EVs during zebrafish embryogenesis, analysing size- and concentration-changes over time. Wild-type AB strain zebrafish larvae (zfl) were collected at 24, 48, 72, and 96 h post fertilization (hpf) and homogenized. …”
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Research note: Whole-genome sequencing revealed genomic diversity dynamics in duck conserved populations by Yu-Ze Yang, Zhong-Tao Yin, Xiao-Ran Lin, Chun-Ying Zhao, Fang-Xi Yang, Fei-Fan Chen, Zhuo-Cheng Hou

“…Overall, the inbreeding coefficient of the conserved Pekin duck population was higher than that of its wild ancestors, indicating that domestication has resulted in reduced genetic diversity. …”
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Unveiling the epidemiology and community perspectives on bovine brucellosis in North Shewa, Central Highlands of Ethiopia by Aweke Engdawork, Abdela Bulbula, Awoke Melak, Haileleul Negussie

“…Abstract Brucellosis is a bacterial disease of many domestic and wild animals with great economic and public health importance. …”
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Genome-wide identification of CAMTA gene family in teak (Tectona grandis) and functional characterization of TgCAMTA1 and TgCAMTA3 in cold tolerance by Wenlong Zhou, Jian Du, Runjie Jiao, Xianbang Wang, Tiansong Fang, Guihua Huang

“…Subcellular localization analysis indicated that these genes were functional predominantly in the nucleus. Compared with wild-type Arabidopsis, TgCAMTA1/3-overexpressing Arabidopsis presented increased tolerance to freezing stress, with increased expression of AtCOR genes. …”
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Alterations in the social-conditioned place preference and density of dopaminergic neurons in the ventral tegmental area in Clsnt2-KO mice by I. N. Rozhkova, S. V. Okotrub, E. Yu. Brusentsev, K. E. Uldanova, E. A. Chuyko, V. A. Naprimerov, T. V. Lipina, T. G. Amstislavskaya, S. Ya. Amstislavsky

“…This study aims to evaluate the social-conditioned place preference as well as density of dopaminergic (DA) neurons in the ventral tegmental area (VTA), which belongs to the brain reward system, in the males of the Clstn2-KO strain using wild type C57BL/6J males as controls. Social-conditioned place preference test evaluates a reward-dependent component of social behavior. …”
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UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1−/− Microglia In Vitro and In Vivo by Hye Min Lim, Heo Woon, Jung Woo Han, Yoshihiro Baba, Tomohiro Kurosaki, Min Goo Lee, Joo Young Kim

“…Their chemotactic migration defect was reproduced in vivo in embryonic brain; the aggregated number of STIM1−/− microglia in LPS- (lipopolysaccharide-) injected lesions was much smaller than that in wild-type microglia. Furthermore, the neuron phagoptosis activities of activated microglia were significantly diminished in the STIM1−/− microglia. …”
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Anisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo by Sizhe Huang, Ruobai Xiao, Shaoting Lin, Zuer Wu, Chen Lin, Geunho Jang, Eunji Hong, Shovit Gupta, Fake Lu, Bo Chen, Xinyue Liu, Atharva Sahasrabudhe, Zicong Zhang, Zhigang He, Alfred J. Crosby, Kaushal Sumaria, Tingyi Liu, Qianbin Wang, Siyuan Rao

“…We fabricate fiber-shaped hydrogels into bioelectronic devices and implant them into wild-type and transgenic Thy1::ChR2-EYFP mice to record electromyographic signals from muscles in anesthetized and freely moving conditions. …”
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Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome by Xin Tao, Katilynne Croom, Adrian Newman-Tancredi, Mark Varney, Khaleel A. Razak

“…Results Saline-injected Fmr1 KO mice showed increased N1 amplitudes, increased STP and reduced phase locking to auditory gap-in-noise stimuli versus wild-type mice, reproducing previously published EEG phenotypes. …”
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A sweeping view of avian mycoplasmas biology drawn from comparative genomic analyses by Elhem Yacoub, Vincent Baby, Pascal Sirand-Pugnet, Yonathan Arfi, Helmi Mardassi, Alain Blanchard, Salim Chibani, Boutheina Ben Abdelmoumen Mardassi

“…Abstract Background Avian mycoplasmas are small bacteria associated with several pathogenic conditions in many wild and poultry bird species. Extensive genomic data are available for many avian mycoplasmas, yet no comparative studies focusing on this group of mycoplasmas have been undertaken so far. …”
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A supervised model to identify wolf behavior from tri-axial acceleration by Charlotte Lorand, Léa Bouet, Olivier Devineau, Marianna Chimienti, Alina L. Evans, Peggy Callahan, Mark Beckel, Timothy G. Laske, Ane Eriksen

“…Abstract Background In wildlife studies, animal behavior serves as a key indicator of the impact of environmental changes and anthropogenic disturbances. However, wild animals are elusive and traditional GPS studies only provide limited insight into their daily activities. …”
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Evaluation of IgG binding capability to SARS-CoV-2 variants in early COVID-19 convalescent sera using an indirect ELISA by Behzad Hussain, Peizhe Zhao, Yu Liu, Bo Yang, Xiaoxiong Li, Zhichao Zhang, Guoqiang Feng, Demei Zhang, Defen Lu, Wu Changxin

“…Our results show that the currently circulating Omicron BQ.1.1, XBB.1.5 and previous Omicron BA.1, BA.2 and BA.4/5 do not show significant reduction in binding, while Omicron BA.3 and previous variants Alpha, Beta, Gamma, Kappa, and Omicron showed a significantly reduced binding when compared to the wild-type Wuhan strain. These results indicate that the patients recovering from natural infection of early original Wuhan strain may have the potential to resist infection of current circulating variants and the vaccines using the prototype antigen may still work for newly emerged variants.…”
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Advancing the Indian cattle pangenome: characterizing non-reference sequences in Bos indicus by Sarwar Azam, Abhisek Sahu, Naveen Kumar Pandey, Mahesh Neupane, Curtis P Van Tassell, Benjamin D Rosen, Ravi Kumar Gandham, Subha Narayan Rath, Subeer S Majumdar

“…Additionally, 70.28% of BICIs are shared with other domesticated and wild species, highlighting their evolutionary significance. …”
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Human_SNP_TATAdb: a database of SNPs that statistically significantly change the affinity of the TATA-binding protein to human gene promoters: genome-wide analysis and use cases by S. V. Filonov, N. L. Podkolodnyy, O. A. Podkolodnaya, N. N. Tverdokhleb, P. M. Ponomarenko, D. A. Rasskazov, A. G. Bogomolov, M. P. Ponomarenko

“…In this work, we integrated into a single database information about SNPs in human gene promoters obtained by automatic extraction from various heterogeneous data sources, as well as the estimates of TBP affinity for the promoter obtained using the three-step binding model and predicting their effect on gene expression for wild-type promoters and promoters with SNPs. We have shown that Human_SNP_TATAdb can be used for annotation and identification of candidate SNP markers of diseases. …”
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Lines resistant to downy mildew in the sunflower genetic collection at VIR by V. A. Gavrilova, T. G. Stupnikova, L. G. Makarova, N. V. Alpatieva, Yu. I. Karabitsina, E. B. Kuznetsova, I. A. Anisimova

“…Lines ТА 716-18, VIR 768 and VIR 800 appeared highly resistant to the pathogen and probably possess new resistance genes/alleles introgressed from wild species.…”
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Identification and characterization of multiple novel viruses in fecal samples of cormorants by Li Ji, Li Ji, Ran Zhao, Yifei Pei, Yijie Sun, Xiaoyi Sun, Likai Ji, Xiaochun Wang, Yuwei Liu, Quan Shen, Shixing Yang, Yan Wang, Wen Zhang

“…IntroductionCormorants, as protected wild animals by the State Forestry Administration of China, have a broad distribution across China. …”
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