Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…This study sought to identify differences in the use of ENDS device type based on age and cigarette use status to inform policy about regulating ENDS.Design This was a cross-sectional study.Setting Data was derived from a national survey conducted in 2021 in the USA.Participants Participants include 2369 US youth and adults (13 years or older) who reported past 30-day ENDS use.Outcome measures Past 30-day fairly regular use (i.e., several times a week or more) of ENDS device types, namely cigalikes, disposables, refillable tank/box mods, closed pods, refillable pods and drippers. …”
Get full text

Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders by Ilene S. Ruhoy, Paolo A. Bolognese, Jared S. Rosenblum, Randall A. Dass, Navdeep S. Nayyer, Navdeep S. Nayyer, Jeffrey D. Wood, Jeffrey D. Wood, John B. Biggins, John B. Biggins

“…Of the total cohort, 426 (59%) were diagnosed with Chiari I Malformation, which shared a significant overlap with hEDS. Of those who elected to undergo surgery (n = 612), 61% required craniocervical fusion (CCF). …”
Get full text

Comparative cardiometabolic safety and effectiveness of aripiprazole in people with severe mental illness: A target trial emulation. by Alvin Richards-Belle, Alvin Richards-Belle, Naomi Launders, Sarah Hardoon, Al Richards, Kenneth K C Man, Neil M Davies, Elvira Bramon, Joseph F Hayes, David P J Osborn

“…., bipolar disorder, schizophrenia, and other non-organic psychoses) who were prescribed a new antipsychotic between 2005 and 2017, with a 2-year follow-up to 2019. …”
Get full text

Preparation of Nutmeg Gel and Evaluation of its Efficacy as Local Drug Delivery in Stage II Grade A Periodontitis Patients: A Prospective Interventional Study by Vazeeha Afrin Syed, AS Pavithra, Arvina Rajasekar, Rajeshkumar Shanmugam

“…Followed by in-vitro analysis, 40 patients with stage II grade A periodontitis patients who reported between June 2023 and September 2023 to the Department of Periodontology were enrolled. …”
Get full text

Comparison of Intraoperative and Postoperative Outcomes of Sleeve and Dorsal Slit Technique of Circumcision: A Prospective Interventional Study by N Snigdha, R Lakshmana, Das Debarath, Natarjan Soorya, A Pravindhas, M Malar Mannan

“…Sixty patients diagnosed with phimosis, balanoposthitis, paraphimosis and patients who requested circumcision for religious reasons were randomly assigned to undergo either the sleeve technique (Group A) or the dorsal slit technique (Group B). …”
Get full text

Association of Time in Target Range of Resting Heart Rate With Adverse Clinical Outcomes in Patients With Acute Coronary Syndromes After Percutaneous Coronary Intervention by Jianmei Zheng, Cen Chen, Zhongcai Fan, Qiang Ye, Yi Zhong, Jinsong Li, Hao Huang, Jianping Deng, Jinghong Zhao, Tinglin Xiong, Wenjie Tian, Xuemei Zhang

“…A total of 1455 ACS patients who underwent percutaneous coronary intervention (PCI) and were admitted to 22 hospitals between 2019 and 2022 were enrolled and followed up for 12 months. …”
Get full text

Effect of Lamotrigine on Refractory Epilepsy: Clinical Outcomes and EEG Changes by Li Z, Wu P, Chen Q, Tong X, Yang Q

“…Lamotrigine, with its proven efficacy and tolerability, offers potential benefits when combined with traditional medications like valproate, though its comprehensive impact on clinical outcomes and neurological markers requires further study.Objective: To analyze the improvement effect of combined application of lamotrigine on refractory epilepsy patients and its impact on patients’ EEG and neurological function.Methods: This retrospective cohort study analyzed the clinical data of 93 patients with refractory epilepsy who were admitted to our hospital between January 2023 and June 2024. …”
Get full text

Real World Experience of Chronic Hepatitis C Retreatment with Genotype Specific Regimens in Nonresponders to Previous Interferon-Free Therapy by Dorota Zarębska-Michaluk, Iwona Buczyńska, Krzysztof Simon, Magdalena Tudrujek-Zdunek, Ewa Janczewska, Dorota Dybowska, Marek Sitko, Beata Dobracka, Jerzy Jaroszewicz, Paweł Pabjan, Jakub Klapaczyński, Łukasz Laurans, Włodzimierz Mazur, Łukasz Socha, Olga Tronina, Miłosz Parczewski, Robert Flisiak

“…We demonstrated moderate effectiveness of genotype specific rescue therapy in failures due to virologic reason and high in those who discontinued primary therapy. Therefore rescue therapy with genotype specific regimens should be considered always if more potent regimens are not available.…”
Get full text

Common mental disorders and associated factors among adult patients admitted in non-psychiatric wards of public hospitals in Harari regional State, Eastern Ethiopia by Hirko Assefa, Tilahun Ali, Ibsa Mussa, Tadesse Misgana, Dawit Abdi, Abinet Zewudie, Abdi Temesgen

“…The study suggested that patients who are admitted to non-psychiatric wards should be screened for common mental disorders and its associated factors as part of routine inpatient care.…”
Get full text

Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: an observational study by John A Schneider, Alan G Nyitray, Derek Smith, Michael W Ross, Elizabeth Y Chiao, Timothy J Ridolfi, Bridgett Brzezinski, B R Simon Rosser, Aniruddha Hazra, Jenna Nitkowski, Sandrine Sanos, Ever Mkonyi, Lucy Mgopa

“…Compared with individuals having always/mostly insertive anal intercourse, individuals having always/mostly receptive anal intercourse were associated with decreased RT, but not ST, while those equally preferring both insertive and receptive anal intercourse were not associated with decreased RT or ST.Conclusion Decreased sphincter tone is uncommon among SGM who prefer receptive anal intercourse. Given virtually no accuracy, a finger inserted into the anus has no utility to detect individuals practising receptive anal intercourse and thus should not be used as such.Trial registration number NCT04090060.…”
Get full text

Advancing Pediatric Surgery: The Use of HoloLens 2 for 3D Anatomical Reconstructions in Preoperative Planning by Marco Di Mitri, Annalisa Di Carmine, Simone D’Antonio, Benedetta Maria Capobianco, Cristian Bisanti, Edoardo Collautti, Sara Maria Cravano, Francesca Ruspi, Michele Libri, Tommaso Gargano, Mario Lima

“…Our prospective observational study, conducted at IRCCS (Scientific Hospitalization and Care Institute) Sant’Orsola-Malpighi University Hospital in Bologna, engaged ten pediatric surgeons, who assessed three types of anatomical malformations (splenic cysts, pulmonary cystic adenomatoid malformations, and pyelo-ureteral junction stenosis) and planned surgeries using both traditional 2D CT scans and 3D visualizations via HoloLens 2, followed by completing a questionnaire to evaluate the utility of each of these imaging techniques in surgical planning. …”
Get full text

Impact of a nurse-led teleconsultation strategy for cardiovascular disease management during COVID-19 pandemic in India: a pyramid model feasibility study by Dorairaj Prabhakaran, Kavita Singh, Ambuj Roy, Bishav Mohan, Rohit Tandon, Abhishek Goyal, Bhupinder Singh, Shibba Takkar Chhabra, Naved Aslam, Gurpreet Singh Wander, Nitish Naik, Gurbhej SIngh, Shivaansh Aggarwal, Aftabh Saini

“…Nurses were trained to provide teleconsultation, triaging of patients and referrals to the physicians. Patients with CVD who had an outpatient visit or hospitalisation between September 2019 and March 2020 at the Dayanand Medical College Hospital, Ludhiana, India, were contacted by phone and offered teleconsultations. …”
Get full text

Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study by Xiao Qin, Junming Ren, Chunping Xing, Lijiao Chen, Renjie Wang, Shouyuan Tian

“…ObjectiveTo investigate the association between high-sensitivity C-reactive protein (Hs-CRP) levels and the risk of postoperative delirium (POD) following general anesthesia.MethodsThis retrospective cross-sectional study included 644 patients who underwent general anesthesia. Univariate and multivariate logistic regression analyses were performed to evaluate the relationship between Hs-CRP and POD, with subgroup analyses used to assess stratified associations. …”
Get full text

A meta-core outcome set for stillbirth prevention and bereavement care following stillbirth in LMIC by Jamie J Kirkham, Declan Devane, Carol Bedwell, Tina Lavender, Tracey A Mills, Sabina Wakasiaka, Rose Laisser, Bellington Vwalika, Nasim Chaudhry, Angela Chimwaza, Elizabeth Ombeva Ayebare, Sudhindrashayana Fattepur, Tayyeba Kiran, Kushupika Dube, Farai Marenga, Idesi Chilinda, Unice Goshomi, Allen Nabisere, Zaib Un Nisa

“…An online real-time Delphi survey was then conducted with healthcare professionals, parents who have experienced a stillbirth and researchers in the field to score the agreed list. …”
Get full text

Autophagy activation in response to cigarette smoke: Exploring the disparity in laryngeal cancer incidence and outcomes between sexes in South Korea by Min Ji Kim, Jisu Hong, Hyo Won Chang, Yun-Hee Lee, Jun-Pyo Myong, Ah Ra Jung, Yoon Se Lee, Minsu Kwon

“…This study sought to investigate whether autophagy, a major mechanism for RE development, acts as a defense mechanism in laryngeal tissue against cigarette exposure and suppresses LC development in females who smoke. Methods: This study analyzed the National Health Insurance Service (NHIS) data of South Korea to explore sex differences in LC incidence and clinical outcomes. …”
Get full text

The prolonged health sequelae “of the COVID-19 pandemic” in sub-Saharan Africa: a systematic review and meta-analysis by Melsew Setegn Alie, Getayeneh Antehunegn Tesema, Getayeneh Antehunegn Tesema, Gossa Fetene Abebe, Desalegn Girma

“…It is crucial for individuals who have recovered from COVID-19 to receive careful follow-up care to assess and reduce any potential organ damage and maintain their quality of life.Systematic review registrationClinicaltrial.gov, identifier CRD42024501158.…”
Get full text

Emergency medicine physician supervision and mortality among patients receiving care from non-physician clinicians in a task-sharing model of emergency care in rural Uganda: a retr... by Rebecca Leff, Brian Rice, Bradley Dreifuss, Heather Hammerstedt, Mark Bisanzo, Stacey Chamberlain, Ashley Pickering, Colleen Laurence, Prisca Mary Kizito, Steven Jonathan Kisingiri, Charles Ndyamwijuka, Serena Nakato, Lema Felix Adriko

“…Overall mortality decreased significantly across supervision cohorts (‘Direct’ 3.8%, ‘Indirect’ 3.3%, ‘Independent’ 2.6%, p<0.001), but so too did the rates of patients who presented with ≥3 abnormal vitals (‘Direct’ 32%, ‘Indirect’ 19%, ‘Independent’ 13%, p<0.001). …”
Get full text

Analisis Keberterimaan Pengguna Taring Dukcapil Menggunakan Metode Technology Acceptance Model (TAM), Delone & Mclean dan Importance Performance Analysis (IPA) by Ayu Nyoman Waisantini Winaya, Komang Setemen, Made WIndu Antara Kesiman

“…Respondents are people who take printed documents at the Dukcapil Service. …”
Get full text

International prevalence of consultation with a naturopathic practitioner: a systematic review and meta-analysis by Amie Steel, Jon Adams, Brenda Leung, Holger Cramer, Matthew J Leach, Jon Wardle, Joshua Goldenberg, Janet Schloss, Rebecca Redmond, Joanna Elizabeth Harnett, Claudine Van de Venter, Andy McLintock, Ryan Bradley, Jason Hawrelak, Kieran Cooley

“…Other prevalence timeframes were reported as secondary measures.Methods Meta-analysis of prevalence data was conducted using random effects models based on individual countries and WHO world regions.Results The literature search identified eight manuscripts summarising 14 studies reporting prevalence for inclusion in the review. …”
Get full text

Exploring the impact and mechanisms of behavioral activation on sleep disorders in colorectal cancer: a randomized controlled trial by Anlong Li, Runze Huang, Han Ge, Dajie Liu, Shaochun Liu, Yingxue Jia, Jiaying Chai, Xinyi Zheng, Lijun Liu, Chen Gan, Jian Xu, Ling Cheng, Mingjun Zhang, Huaidong Cheng

“…Methods The study included 101 CRC patients with sleep disturbances, who were randomly assigned to either the BA group (n = 53) or the usual care (UC) group (n = 48). …”
Get full text