Efficacy of Chinese traditional quadruple single pill combination versus valsartan/hydrochlorothiazide for the treatment of hypertension (COSPQ-BP): study protocol for randomised c... by Kai Liu, Yu Yan, Xin Zhang, Yanan Li, Yuanyuan Yao, Lu Liu, Runyu Ye, Si Wang, Xiangyu Yang, Xiaoping Chen, Shanshan Jia, Qingtao Meng, Xianghao Zuo

“…It is widely employed in primary medical institutions and has favourable efficacy, tolerability and cost-effectiveness.Methods and analysis The COSPQ-BP trial is a 12-week prospective randomised controlled trial to enrol 1332 patients with primary mild-to-moderate hypertension. Participants who meet the inclusion criteria will be randomly assigned to a 1:1 ratio to an intervention group (compound reserpine and triamterene tablets) or a control group (valsartan/hydrochlorothiazide). …”
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DESKRIPSI MINAT DAN HASIL BELAJAR SISWA DENGAN MODEL DIRECT INSTRUCTION BERBASIS MIND MAPPING PADA PEMBELAJARAN IPA DI SMPN 3 KEPAHIANG by Aulia Wulandari, Connie Connie, Eko Risdianto

“…The research subjects were students of class VII D SMP Negeri 3 Kepahiang 2018/2019 school year who received 25 students. The technique of collecting data using a questionnaire to see student learning interests, test sheets to see student learning outcomes and task sheets to see the ability of students to make mind mapping. …”
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Early results of primary total hip arthroplasty performed in young adults at a regional Saudi-Arabian orthopedics center: a prospective observational study by Walid M. Al-Shaer, Ali H. Al-Yami, Mokhtar Ahmed Al-Sayed, Ali Mohammed Al-Zaidan, Emad Ruddah Al-Sufyani, Ahmed A. Khalifa, Raad M. M. Al-Thaqafi, Abdulmohsen H. Al-Hamyani, Mohammed M. Al-Subaie

“…We conducted a prospective observational study over one year by following all patients (≤40 years) who underwent primary THA at a regional Saudi-Arabin orthopedics center. …”
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Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient in... by Emilia Riggi, Marco Barbero, Gian Luca Di Tanna, Ruth Hersche, Andrea Weise

“…The estimated sample size to detect a post-intervention difference of 1.5 points in self-efficacy to implement energy conservation strategies with 90% power (0.05 alpha) is 122 people (1:1 ratio).Persons with long COVID-related fatigue who follow EME as part of their standard care will be recruited and included in the experimental group (EG), while potential participants for the control group (CG) will be recruited from a register and prospectively matched to a participant in the EG by applying the propensity score technique. …”
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Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study by Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

“…A digital deception detection procedure was implemented for those who were deemed pre-eligible (n=1928). This procedure resulted in 26% (501/1928) of prescreeners being flagged as potentially deceptive. …”
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Oncologic oUTcomes of neoadjuvant chemotherapy for obSTructive colon cAncer after steNt decompression (OUTSTAND trial); A study protocol of multicenter non-inferiority randomized c... by Bong-Hyeon Kye, Ji-Hoon Kim, Hyung-Jin Kim, Yoon-Suk Lee, In-Kyu Lee, Won Kyung Kang, Hyeon-Min Cho, Jong-Kyung Park, Chang-Hyeok Ahn, Jae-Im Lee, Seong-Taek Oh, Byung Jo Choi

“…However, there are currently no available prospective data on the impact of bridging period and there is a lack of research on the effects of neoadjuvant chemotherapy during the bridging period. Objectives Patients who undergo successful SEMS placement for obstructive left-sided colon adenocarcinoma without metastases will be eligible for this study. …”
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Risk Factors of Anaemia among Children under Five Years in the Hohoe Municipality, Ghana: A Case Control Study by Phyllis Atta Parbey, Elvis Tarkang, Emmanuel Manu, Hubert Amu, Martin Amogre Ayanore, Fortress Yayra Aku, Sorengmen Amos Ziema, Samuel Adolf Bosoka, Martin Adjuik, Margaret Kweku

“…The prevalence of anaemia was high (53.8%), while children whose mothers received iron supplementation during pregnancy were 7.64 times more likely to be anaemic compared with those who did not [AOR=7.64 (95% CI:1.41-41.20.93); p=0.018]. …”
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The relationship between cognitive function and neuropsychiatric disorders with quantitative electroencephalogram (qEEG) on long COVID syndrome patients by Yetty Ramli, Pukovisa Prawiroharjo, Winnugroho Wiratman, Eric Tenda, Nurhadi Ibrahim, Damar Susilaradeya, Abdi Reza, Jennifer Agatha, Rejoel Siagian, Hazrina Fauhan, Florencia Evelyn, Yoshikazu Ugawa, Prasandhya Yusuf

“…Methods: This cross-sectional study compared patients with long COVID to those who had recovered from COVID-19 without residual symptoms using quantitative electroencephalogram (qEEG) analysis. …”
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Pengembangan Game Edukasi Bilomatika untuk Meningkatkan Hasil Belajar Siswa pada Mata Pelajaran Matematika Kelas 1 SD by Risqi Ervera Nur Arifah, Sukirman Sukirman, Sujalwo Sujalwo

“…Validation of the educational game application is carried out by two media experts and material experts who are competent in the fields with a percentage value of 80.5% and 85.2%, so that it falls into the very feasible category. …”
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Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study by Tone Merete Norekvål, Jørund Langørgen, Torbjørn Omland, Øyvind Skadberg, Kjell Vikenes, Nasir Saeed, Ole-Thomas Steiro, Hilde Lunde Tjora, Rune Oskar Bjørneklett, Vernon Vijay Singha Bonarjee, Øistein Rønneberg Mjelva, Kristin Moberg Aakre

“…NSTEMI and UAP patients who were revascularised reported higher scores (p<0.05) in SAQ-7-QL, SAQ7-PL, SAQ7-summary (NSTEMI) and all SAQ-7 domains (UAP). …”
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Deep learning-based CT radiomics predicts prognosis of unresectable hepatocellular carcinoma treated with TACE-HAIC combined with PD-1 inhibitors and tyrosine kinase inhibitors by Linan Yin, Ruibao Liu, Wei Li, Shijie Li, Xunbo Hou

“…Methods This retrospective study included 172 patients with uHCC who underwent combination therapy of TACE-HAIC with TKIs and PD-1 inhibitors. …”
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Effect of differences in vascular anatomy on surgical outcomes of left pancreatectomy: a retrospective study by Masahiro Fukada, Noriki Mitsui, Takeshi Horaguchi, Yuji Hatanaka, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Shigeru Kiyama, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi

“…Methods This was a single-center retrospective study involving 123 patients who underwent left pancreatectomy (LP). We analyzed the correlation between vascular anatomical variations, namely, (i) the root of the splenic artery (SpA; types 1 and 2), (ii) the parent artery of the dorsal pancreatic artery, (iii) confluence patterns of the left gastric vein, and (iv) the inferior mesenteric vein, and surgical outcomes. …”
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Smoking and secondhand smoke exposure and carotid intima-media thickness: Baseline data from the Aidai Cohort Study in Japan by Makoto Saito, Yoshihiro Miyake, Keiko Tanaka, Chisato Nagata, Hidenori Senba, Yasuko Hasebe, Toyohisa Miyata, Takashi Higaki, Eizen Kimura, Bunzo Matsuura, Osamu Yamaguchi, Ryuichi Kawamoto

“…The prevalence of never smoking was 30.5% in men and 90.1% in women. Among those who had never smoked, the prevalence of never SHS exposure at home and work was 74.3% and 48.2% in men and 38.3% and 56.3% in women, respectively. …”
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Hubungan Derajat Obesitas dengan Kadar Gula Darah Puasa pada Masyarakat di Kelurahan Batung Taba dan Kelurahan Korong Gadang, Kota Padang by Andi Fadilah Yusran Putri, Eva Decroli, Ellyza Nasrul

“…The objective of this study was to determine the relationship of the degree of obesity and fasting blood glucose of people who live in Kelurahan Batung Taba and Kelurahan Korong Gadang, Padang City. …”
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Real-World Life Analysis of a Continuous Glucose Monitoring and Smart Insulin Pen System in Type 1 Diabetes: A Cohort Study by Paola Pantanetti, Giovanni Cangelosi, Sara Morales Palomares, Gaetano Ferrara, Federico Biondini, Stefano Mancin, Gabriele Caggianelli, Mauro Parozzi, Marco Sguanci, Fabio Petrelli

“…Methods: A retrospective observational study was conducted among adults with T1D who initiated Medtronic Smart MDI therapy. Participants were enrolled voluntarily at the Diabetes and Nutrition Clinic in Ast Fermo, Marche Region, Italy. …”
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Pengembangan Aplikasi E-Learning Edu IT : Pembuatan Aplikasi Ujian Essay Online serta Upload Download Materi Kuliah by Maria Bellaniar Ismiati, Latius Hermawan

“…Abstract The world of education is now many who use technological sophistication and internet based, such as the process of teaching electronic learning/which is known as e-learning. …”
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Hubungan Antara Tingkat Aktivitas Fisik dengan Fungsi Kognitif pada Usila di Kelurahan Jati Kecamatan Padang Timur by Milfa Sari Muzamil, Afriwardi ., Rose Dinda Martini

“…The study population was elderly ≥ 60 years who reside in the Village of Jati, East Padang district and fit the inclusion and exclusion criteria. …”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…In the UTUC advanced stages, the OR of virus and LT expression was 3.18-fold higher compared to those who do not require chemotherapy. Conclusions JCPyV infection is highly prevalent in UTUC, and the presence of CKD concurrent with high expressions of LT and mutant p53 proteins in patients may be a useful indicator for chemotherapy and poor prognosis.…”
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95-95-95 HIV indicators among children younger than 15 years in South Africa: results from the 2017 national HIV prevalence, incidence, behaviour, and communication survey by Rindidzani E. Magobo, Musawenkosi Mabaso, Sean Jooste, Lesiba Molopa, Inbarani Naidoo, Leickness Simbayi, Khangelani Zuma, Nompumelelo Zungu, Olive Shisana, Sizulu Moyo

“…Among CLHIV, the odds of testing and knowing the HIV-positive status were significantly higher among children whose health was rated as fair/poor than excellent/good [AOR = 1.32 (95%CI: 1.05–1.67), p = 0.022], and were significantly lower among females than males [AOR = 0.82 (95% CI: 0.71–0.95), p = 0.009], and were significantly lower among those attending private healthcare facilities than public health facilities [AOR = 0.64 (95% CI:0.57–0.74), p < 0.001]. Among those who knew their HIV-positive status, the odds of being on ART were significantly higher among children residing in farm areas than urban areas [AOR = 1.40 (95% CI:1.05–1.86), p = 0.017], and were significantly lower among children attending private healthcare facilities [AOR = 0.44 (95% CI:0.36–0.54), p < 0.001]. …”
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Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety by Zhao X. Hu, Yi N. Ye, Wei G. Wu, Xu J. Liang, Qi W. Wu, Ao Zhang, Xing R. Zheng, Zhi L. Gao, Liang Peng, Chan Xie

“…Additionally, 61.47% of physicians considered telbivudine or tenofovir as the first choice for male patients who met antiviral criteria, whereas 19% suggested delayed therapy and follow-up until childbirth. …”
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