Very first real-world data on zongertinib use in non-small cell lung cancer patients with HER2 mutations: A brief report by Oliver Illini, Anna Sophie Lang-Stöberl, Hannah Fabikan, Christoph Weinlinger, Arschang Valipour, Maximilian J. Hochmair

“…Methods: We report real-world data on six consecutive patients with HER2-mutant NSCLC who received zongertinib through a named patient use program between December 2023 and June 2024. …”
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Increased Mortality After Lower Extremity Amputation in a Danish Nationwide Cohort: The Mediating Role of Postoperative Complications by Brix ATH, Petersen TG, Nymark T, Schmal H, Lindberg-Larsen M, Rubin KH

“…Windsløws vej 4, Odense, 5000, Denmark, Tel +45 3027 2862, Email anna.trier.heiberg.brix@rsyd.dkObjective: Patients who undergo major lower extremity amputation (MLEA) have the highest postoperative mortality among orthopedic patient groups. …”
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Barriers and facilitators to implementation of a home-based cardiac rehabilitation programme for patients with heart failure in the NHS: a mixed-methods study by Rod S Taylor, Paulina Daw, Samantha B van Beurden, Jet J C S Veldhuijzen van Zanten, Alexander Harrison, Sinead T J McDonagh, Patrick J Doherty, Colin J Greaves, Hasnain M Dalal, Grace E R Wood

“…The online survey was later offered to subsequent NHS staff who took part in the online REACH-HF training. Normalisation Process Theory was used as a theoretical framework to guide data collection/analysis.Results Seventeen healthcare professionals working at the Beacon Sites were interviewed and 17 survey responses were received (20% response rate). …”
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Comparison of sagittal measurements of cervical spine in spondylosis patients between Magnetic Resonance Imaging and Radiograph [version 1; peer review: 2 approved] by Rajagopal Kadavigere, Saikiran Pendem, Varsha R, Tancia Pires, Surbhi Gupta Aggarwal, Shailesh S Nayak, Priyanka -, Maria Nicolet

“…Methods The study was done retrospectively. 77 patients who underwent both MRI and radiograph were included in the study. …”
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Mediolateral episiotomy and obstetric anal sphincter injuries in nullipara: a propensity score matching study by Or Bercovich, Daniela Chen, Bar Narkis, Anat Pardo, Eran Hadar, Asnat Walfisch, Ohad Houri

“…Methods Retrospective study of all nulliparous women with a singleton gestation who underwent term vaginal delivery or vacuum-assisted delivery. …”
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miR-182 promoter hypermethylation predicts the better outcome of AML patients treated with AZA + VEN in a real-world setting by Yilan Xu, Danyang Li, Na Wang, Bei Ge, Chen Meng, Min Zhao, Zihan Lin, Min Li, Yigang Yuan, Yue Cai, Liuzhi Shi, Shenmeng Gao, Haige Ye

“…Abstract Background 5-Azacytidine (AZA) combined with the BCL2 inhibitor Venetoclax (VEN) is the standard treatment for elderly acute myeloid leukemia (AML) patients or those who are unfit for intensive chemotherapy (elderly or unfit AML). …”
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Examine the Availability and Safety of Mucosal Cutting Biopsy Technique for Diagnosis of Gastric Submucosal Tumor by Kazuhiro Mizukami, Osamu Matsunari, Ryo Ogawa, Yuka Hirashita, Kazuhisa Okamoto, Kensuke Fukuda, Akira Sonoda, Hidetoshi Akiyama, Sotaro Ozaka, Yoshinari Kawahara, Tadayoshi Okimoto, Masaaki Kodama, Kazunari Murakami

“…The subjects were patients aged ≥20 years old in whom an SMT was seen on esophagogastroduodenography and who underwent MCB between January 2012 and December 2016. …”
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Corticosteroid Pulses for Hospitalized Patients with COVID-19: Effects on Mortality by Ivan Cusacovich, Álvaro Aparisi, Miguel Marcos, Cristina Ybarra-Falcón, Carolina Iglesias-Echevarria, Maria Lopez-Veloso, Julio Barraza-Vengoechea, Carlos Dueñas, Santiago Antonio Juarros Martínez, Beatriz Rodríguez-Alonso, José-Ángel Martín-Oterino, Miguel Montero-Baladia, Leticia Moralejo, David Andaluz-Ojeda, Roberto Gonzalez-Fuentes

“…We selected patients with confirmed COVID-19 and lung involvement with a pO2/FiO2<300, excluding those exposed to immunosuppressors before or during hospitalization, patients terminally ill at admission, or those who died in the first 24 hours. We performed a propensity score matching (PSM) adjusting covariates that modify the probability of being treated. …”
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Emotion regulation-based internet-delivered cognitive behavioural therapy for premenstrual dysphoric disorder: study protocol for a randomised controlled trial in Sweden by Filipa Sampaio, Alkistis Skalkidou, Gerhard Andersson, Cornelia Weise, Johanna M. Hoppe, Maria Kleinstaeuber, Johan Vegelius, Erika Comasco, Maria Gröndal, Elisavet Kaltsouni, Felicia Sundström, Monica Buhrman

“…Following recruitment and inclusion, 164 individuals aged 18–45 years who fulfil the Diagnostic Manual of Mental Disorders-5 criteria for PMDD will be randomly assigned to the two groups. …”
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An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced bi... by Shaker Hassan S. Alshehri, Mastour Saeed Alshahrani, Saeed Y. Al Adal, Faisal M. Alyazedi, Hani Hassan Alnakhli, Ravi Shankar Reddy

“…Abstract Background Ankle joint position sense (AJPS) accuracy and postural control are crucial for maintaining balance and stability, particularly in individuals with plantar fasciitis who may experience proprioceptive and functional impairments. …”
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Novel models based on machine learning to predict the prognosis of metaplastic breast cancer by Yinghui Zhang, Wenxin An, Cong Wang, Xiaolei Liu, Qihong Zhang, Yue Zhang, Shaoqiang Cheng

“…Radiotherapy is considered more appropriate for patients who have undergone breast-conserving surgery with M0 stage as well as those in stage T3-4/N2-3M0 undergoing mastectomy.…”
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Segmentasi Pelanggan B2B dengan Model LRFM Menggunakan Algoritma Fuzzy C-Means pada Rotte Bakery by Dea Putri Ananda, Siti Monalisa

“…Abstract B2B customers (Business to Business) are customers who purchase products from a company with the intention of reselling them to end consumers. …”
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Short-term costs of alcohol-associated hepatitis care in different clinical settings by Chi Mai Nguyen, Jing Su, Yang Li, Ryan Healey, Shihui Jiang, Jiangqiong Li, Naga Chalasani, Samer Gawrieh, Suthat Liangpunsakul, Wanzhu Tu

“…Costs increase significantly with high-cost comorbidity clusters and among patients who die, underscoring the need for effective management of comorbidities in AH care.…”
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Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Outcomes Among Patients with Trauma in the Emergency Department: A Comparison with the Modified Early Warni... by Min Woo Kang, Seo Young Ko, Sung Wook Song, Woo Jeong Kim, Young Joon Kang, Kyeong Won Kang, Hyun Soo Park, Chang Bae Park, Jeong Ho Kang, Ji Hwan Bu, Sung Kgun Lee

“…Methods This study was a cross-sectional study of trauma patients who visited the emergency department of Jeju National University Hospital. …”
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Early health technology assessment of tongue swab for non-sputum based pulmonary tuberculosis diagnosis in ThailandResearch in context by Langming Mou, Teerawat Wiwatpanit, Apiwat Piriyapol, Puwadol Chawengkul, Janjira Thaipadungpanit, Puttarin Kulchaitanaroaj, Yot Teerawattananon, Yi Wang

“…Summary: Background: Sputum-based diagnostic methods for pulmonary tuberculosis (PTB) are challenging for patients who cannot produce sputum. Non-sputum-based approaches, such as tongue swab (TS), can address this gap. …”
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Perbedaan Rerata Kadar Gula Darah pada Luaran Stroke Iskemik Berdasarkan Indeks Barthel by Muhammad Iqbal, Meiti Frida, Rismawati Yaswir

“…This analytic research with a retrospective design by obtaining datas from medical records of patient who hospitalize in department of neurology RSUP Dr. …”
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Analysis of Optimal Health-Related Quality of Life Measures in Patients Waitlisted for Lung Transplantation by Junko Tokuno, Toyofumi F Chen-Yoshikawa, Toru Oga, Takahiro Oto, Tomoyo Okawa, Yoshinori Okada, Miki Akiba, Masaki Ikeda, Daisuke Nakajima, Masatsugu Hamaji, Hideki Motoyama, Akihiro Aoyama, Maki Isomi, Kazuo Chin, Hiroshi Date

“…The MRF-26 Total and SRI Summary significantly worsened from the baseline to 1 year (p<0.001 and p=0.010, respectively) in 103 patients who underwent a follow-up assessment without lung transplantation, while the SGRQ showed a marginal significant worsening (p=0.040). …”
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Association between beta‐blocker atenolol use and prostate cancer upgrading in active surveillance1 by Ali H. Zahalka, Ethan Fram, Evan Garden, Lauren Howard, Emily Wiggins, Mustufa Babar, Jay Annam, Allison Reagan, Benjamin Eilender, Amanda deHoedt, Stephen J. Freedland, Ash Tewari, Kara L. Watts

“…Patients and Methods Men with low‐risk or favourable intermediate‐risk prostate cancer who were placed on an active surveillance protocol between 2006 and 2020 across three diverse urban hospitals were included. …”
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Effect of Proteinuria Before Lenvatinib Administration on Treatment Response After Atezolizumab Bevacizumab Combination Therapy by Hironori Ochi, Masayuki Kurosaki, Takaaki Tanaka, Nobuharu Tamaki, Kaoru Tsuchiya, Yutaka Yasui, Hiroyuki Marusawa, Toshifumi Tada, Shinichiro Nakamura, Takehiro Akahane, Eisuke Okamoto, Haruhiko Kobashi, Hirotaka Arai, Michiko Nonogi, Namiki Izumi

“…Methods We examined 64 patients who were administered lenvatinib as second‐line treatment after discontinuation of atezolizumab and bevacizumab. …”
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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…This study evaluates changes in participant quality of life (QoL), unmet needs and mental health over time based on their genetic variant status.Methods and analysis This prospective cohort study will recruit 1435 patients with suspected hereditary cancer who have undergone BRCA1/2 or next-generation sequencing (NGS) testing. …”
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