Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma by Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama, Yuri Nishioka, Masaya Uesato, Koichi Hayano, Akira Nakano, Hisahiro Matsubara

“…Methods Tissue specimens were collected from 126 patients with ESCC who underwent curative esophagectomy. Immunohistochemical analysis and multiplex immunofluorescence for CD4, CD8, CD25, FOXP3, and PD‐L1 in the tumor were used to identify multiple tumor‐infiltrating immune cells (TIIC), Tregs, and TC. …”
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Comparing the clinical efficacy of prostate enucleation by the Millin method and enucleation performed using a holmium laser (HoLEP) with a prostate volume more than 80 cm<sup>3</s... by S. N. Volkov, V. S. Stepanchenko, V. I. Tereshchenko, A. R. Dzharimok, O. R. Grigoryan, R. K. Mikheev

“…The results were obtained illustrating a shorter inpatient stay for patients who underwent HoLEP (4.3 ± 0.6 days versus 10.0 ± 2.4 during Millin surgery), which is correspondingly associated with a faster recovery after this intervention compared with the classic one. …”
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PENGARUH MODEL QUANTUM LEARNING TERHADAP PEMAHAMAN KONSEP DAN HASIL BELAJAR SISWA KELAS X by Anisa Anisa, Rosane Medriati, Desy Hanisa Putri

“…The results showed that understanding the concept with the Quantum Learning Model with an average of 80.45 was higher than that of students who took part in the Direct Instruction Model with an average of 60.12 and t calculated the understanding of the concept of 9.71 which was greater than ttable namely 1.67155 and learning outcomes with the Quantum Learning Model with an average value of 80.61 higher than the control class with an average of 57.29. …”
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Abyssinian pea (Lathyrus schaeferi Kosterin nom. nov. pro Pisum abyssinicum A. Br.) is a problematic taxon by O. E. Kosterin

“…Braun), in honour of Hanno Schaefer, who substantiated the revision of tribe Fabeae by molecular reconstruction of its phylogeny. …”
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Sobre fogones y semáforos: Percepciones y analogías de dos geografías desencontradas. El caso del volcán Callaqui en la geografía ancestral pehuenche de Alto Biobío by Claudio Contreras Véliz

“…This text is based on an extensive ethnographic work, and it exposes the disagreement in the appreciation and appropriation of local geography, between the perception of the culture of the Pehuenche people who inhabit it, and the institutionality and emergency regulations that intervene in it.…”
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Genetic diversity and transmission pattern of multidrug-resistant tuberculosis based on whole-genome sequencing in Wuhan, China by Liqing Wei, Jun Chen, Zhen Deng, Zefang Zhang, Zhengbin Zhang, Qionghong Duan

“…Notably, rare mutations absent from the WHO mutation catalog, such as ahpC c-52C &gt; T and rpsL Lys43Thr, were also observed. …”
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Long-term effects of dupilumab on chronic rhinosinusitis with nasal polyps: A step towards clinical remission by Mona Al-Ahmad, MD, FRCPC, Asmaa Ali, MD, PhD, Wafaa Talat, MD, PhD, Haitham A. Dawood, MD, PhD, Osama Imam, MD, PhD

“…Methods: A two-year prospective study was conducted on 109 patients with CRSwNP, with or without asthma, who were eligible for dupilumab as an add-on therapy. …”
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Prevalence of Food Insecurity and Its Associated Factors among Adult People with Human Immunodeficiency Virus in Ethiopia: A Systematic Review and Meta-Analysis by Hagos Degefa Hidru, Haftay Gebremedhine, Alem Gebretsadik, Hirut Teame, Hadush Negash, Meresa Berwo Mengesha

“…Cluster of differentiation 4 CD4 count<350 cell/mm3 [AOR=1.29 (95% CI, 1.08, 1.54)], develop opportunistic infection [AOR=4.09 (95% CI, 2.47, 6.78)], rural residence [AOR=1.59 (95% CI, 1.09, 2.34)], and World Health Organization (WHO) clinical stages III and IV [AOR=1.98 (95% CI, 1.23, 3.19)] was among the significantly associated factors. …”
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Prevalence of hypertension in Shenzhen, China: a population-based, cross-sectional study by Ke Peng, Ji Peng, Yirong Wang, Weicong Cai, Lin Lei, Rencheng Zhao, Fangjiang Liu, Kaihao Lin, Fengzhu Xie

“…Among patients with HTN, 55.0% (95% CI 52.9 to 57.1) were aware of their condition and 44.9% (95% CI 42.8 to 47.1) were taking antihypertensive medications, but only 21.7% (95% CI 20.0 to 23.5) achieved BP control. Among those who knew their HTN, 81.7% (95% CI 79.3 to 83.8) were under treatment and 48.3% (95% CI 45.1 to 51.5) were controlled among those with treated HTN. …”
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Predicting breast cancer prognosis using PR and PIK3CA biomarkers: a comparative analysis of diagnostic groups by Yuting Feng, Qingzhen Song, Lei Yan, Ruoqi Li, Mengqin Yang, Peng Bu, Jing Lian

“…Abstract Purpose To evaluate the prognostic significance of progesterone receptor (PR) expression and the PIK3CA mutation status in HR+/HER2 − breast cancer patients, with the goal of screening patients who may derive the greatest benefit from PI3K-targeted therapy. …”
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Randomised controlled trial of topical kanuka honey for the treatment of rosacea by James Fingleton, Mark Weatherall, Richard Beasley, Irene Braithwaite, Janwillem Kocks, Mark Holliday, Andrew Corin, Colin Helm, Davitt Sheahan, Barney Montgomery, Judith Riley, Anna Hunt, Christopher Tofield

“…Objective To investigate the efficacy of topical 90% medical-grade kanuka honey and 10% glycerine (Honevo) as a treatment for rosacea.Design Randomised controlled trial with blinded assessment of primary outcome variable.Setting Outpatient primary healthcare population from 5 New Zealand sites.Participants 138 adults aged ≥16, with a diagnosis of rosacea, and a baseline blinded Investigator Global Assessment of Rosacea Severity Score (IGA-RSS) of ≥2. 69 participants were randomised to each treatment arm. 1 participant was excluded from the Honevo group, and 7 and 15 participants withdrew from the Honevo and control groups, respectively.Interventions Participants were randomly allocated 1:1 to Honevo or control cream (Cetomacrogol), applied twice daily for 8 weeks.Main outcome measures The primary outcome measure was the proportion of participants who had a ≥2 improvement in the 7-point IGA-RSS at week 8 compared to baseline. …”
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« Pas de retour à nos maisons sans satisfaction de nos revendications ». Le Hirak du Rif en actes face au Makhzen by Ahmed Chapi

“…However, the protests continue in the following weeks, through night-time rallies in the neighborhoods, pot-banging and marches (some of which on the beaches), thanks to activists embedded in the movement's mobilization networks who have not (yet) been detained. These activists remain committed despite the heightened risks, as they gradually develop or strengthen a strong inclination to protest, taking part in various actions throughout the protest sequence (such as surprise demonstrations and neighborhood rallies). …”
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Effect of ticagrelor combined with metoprolol extended-release tablets on cardiac function and clinical prognosis in elderly patients with acute coronary syndrome after percutaneou... by Lili Wang, Linlin Gao, Qin Chen, Li Chen, Hui Xu, Ling Sun, Youbin Hu

“…This study sought to assess the impact of combining ticagrelor and metoprolol extended-release tablets on clinical prognosis and cardiac function in elderly ACS patients following percutaneous coronary intervention (PCI).MethodsFrom February 2022 to February 2023, 90 elderly ACS patients who underwent PCI at our institution were retrospectively enrolled and divided into two groups: an observation group (OG) and a control group (CG), with 45 patients in each group. …”
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Legal regime of property registration: civil-legal aspect by Serdyuk R.

“…It is substantiated that the scientific approach, according to which in inheritance relations the fact of state registration of rights to inherited property has a legal character and retrospectively determines the emergence of rights to such property by the person who entered the inheritance, is debatable. Originality. …”
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Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…A limited search for grey literature will be conducted using the WHO Institutional Repository for Information Sharing. …”
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Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report by Alaina P. Vidmar, Linus Kaiser, Matthew J. Martin, Stuart Abel, Aimee G. Kim, Madeleine Weitzner, Cynthia E. Muñoz, Lynda K. Fisher, Mimi S. Kim, Kamran Samakar

“…Case presentation We present the case of an 18-year-old Hispanic male with classic congenital adrenal hyperplasia and class III obesity, who underwent a multimodal obesity treatment plan. …”
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Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients by Nevedha Rajan, Toni Kavanagh, Maite LaVega‐Talbott, Sandeep Gangadharan

“…Methods This was a single center retrospective observational cohort study that analyzed data from patients 2–18 years old who presented with concerns for SE. For rrEEG patients, the bedside physician used the Brain Stethoscope at four discrete points. …”
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Association between Brain-Derived Neurotrophic Factor (BDNF) Levels in 2nd Trimester Amniotic Fluid and Fetal Development by Nikolaos Antonakopoulos, Zoe Iliodromiti, George Mastorakos, Christos Iavazzo, Georgios Valsamakis, Nikolaos Salakos, Aris Papageorghiou, Alexandra Margeli, Sophia Kalantaridou, George Creatsas, Efthymios Deligeoroglou, Nikolaos Vrachnis

“…In accordance with our study design, samples of amniotic fluid were collected from women who had undergone amniocentesis early in the 2nd trimester. …”
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Clinical characteristics of Plasmodium vivax malaria infection in children and adolescents in the Republic of Korea during the period 2000 to 2016: a retrospective study by Jung Ah Lee, Je Eun Song, Seong Yeon Park, Yoon Soo Park, Yoonseon Park, Yee Gyung Kwak, Sang-Eun Lee, Hyun-Il Shin, Joon-Sup Yeom

“…Abstract Background Although Plasmodium vivax (P. vivax) malaria is in the pre-elimination phase in the Republic of Korea (ROK), it continues to affect children and adolescents, who account for approximately 4–6% of the 300 to 500 annual cases. …”
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The efficacy and safety of induction chemotherapy combined with sintilimab followed by concurrent chemoradiotherapy plus sintilimab sequencing maintaining with sintilimab for patie... by Ruifeng Wang, Tianhui Guo, Qi Wang, Wen Gao, Yimiao Yu, Jun Zhang, Wenqian Fu, Haiji Wang, Biyuan Zhang

“…Methods Data from patients with histologically confirmed, locally advanced, inoperable ESCC who received IC-ICCRT-IO were retrospectively analyzed. …”
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