An interactive course program on nutrition for medical students: interdisciplinary development and mixed-methods evaluation by Gonza B. Ngoumou, Daniela A. Koppold, Laetitia Wenzel, Anne Schirmaier, Carolin Breinlinger, Lisa M. Pörtner, Stefan Jordan, Julia K. Schiele, Etienne Hanslian, Annika Koppold, Beate Stock-Schröer, Dimitra M. Varvarezou, Michael Jeitler, Miriam Ortiz, Andreas Michalsen, Wiebke Stritter, Georg Seifert, Christian S. Kessler

“…Here, we present a two-week course for medical students in the 8th semester at Charité - Universitätsmedizin Berlin on nutrition and fasting in the context of human and planetary health. …”
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Role of sphingolipid metabolism signaling in a novel mouse model of renal osteodystrophy based on transcriptomic approach by Yujia Wang, Yan Di, Yongqi Li, Jing Lu, Bofan Ji, Yuxia Zhang, Zhiqing Chen, Sijie Chen, Bicheng Liu, Rining Tang, Yuanyuan Ji

“…To address this gap, we established a stable mouse model of ROD using an optimized adenine-enriched diet and conducted exploratory analyses through ribonucleic acid sequencing (RNA-seq). Methods:. Eight-week-old male C57BL/6J mice were randomly allocated into three groups: control group (n = 5), adenine and high-phosphate (HP) diet group (n = 20), and the optimized adenine-containing diet group (n = 20) for 12 weeks. …”
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Clinical Observation of Auricular Acupressure Combined with Transcranial Direct Current Stimulation for Nicotine Dependence by KUANG Hongjun, FU Shanshan, HUANG Qian, YANG Layuan, YUAN Yangyang, YUAN Nan, LIU Minquan, TANG Jian, FANG Chuang, ZHONG Feng

“…In addition, the auricular acupressure pads were changed every 2 days, three times per week, for four weeks. In the tDCS group, tDCS was applied at the dorsolateral prefrontal cortex, 1.4 mA in intensity, 20 min each time, three times per week, for four weeks. …”
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Eosinophil is a predictor of severe immune-related adverse events induced by ipilimumab plus nivolumab therapy in patients with renal cell carcinoma: a retrospective multicenter co... by Yoshihiko Tasaki, Shuzo Hamamoto, Shimpei Yamashita, Junya Furukawa, Kazutoshi Fujita, Ryotaro Tomida, Makito Miyake, Noriyuki Ito, Hideto Iwamoto, Yoshihisa Mimura, Yosuke Sugiyama, Rei Unno, Atsushi Okada, Takahiro Yasui, Yoko Furukawa-Hibi

“…We examined the proportion of eosinophils before and 2 weeks after treatment (baseline and 2-week samples, respectively).ResultsAlthough the eosinophil in the baseline samples did not differ between the severe irAE and non-irAE groups (2.8% vs. 2.5%, P = 0.75), regarding the 2-week samples, the eosinophil was significantly higher in the severe irAE group (mean, 6.6% vs. 3.3%; P < 0.05). …”
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Effect of Acupotomy Intervention on Fibrosis of Rectus Femoris in Rabbits with Knee Osteoarthritis by LIU Jing, ZENG Weiquan, LIN Qiaoxuan, LU Liming, GUO Zexing, LIU Hong, ZHANG Liangzhi, XIU Zhongbiao

“…Modified Videman method was used to replicate the osteoarthritis model of the knee with left hind limb extended plaster immobility for 6 weeks. Lequesne MG knee joint grade score, X-ray and MRI imaging examination of knee joint and pathological morphology of rectus femoris were confirmed after successful modeling. …”
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Efficacy of a Mobile Health–Based Behavioral Treatment for Lifestyle Modification in Type 2 Diabetes Self-Management: Greenhabit Randomized Controlled Trial by Ana Maria Ruiz-Leon, Rosa Casas, Sara Castro-Barquero, Sofia Alfaro-González, Petia Radeva, Emilio Sacanella, Francesc Casanovas-Garriga, Ainhoa Pérez-Gesalí, Ramon Estruch

“…Repeated-measures analysis of variance was used to compare changes over time (baseline to 6 weeks and baseline to 12 weeks) between the 2 intervention groups. …”
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Effect of Ingestion Training Guided by Volume-viscosity Swallow Test on Post-Stroke Dysphagia by DENG Li, HE Yingzi, JIN Yanping, LU Yan

“…The control group received traditional rehabilitation training, such as conventional therapy, cold stimulation training, mouthwash and so on, 15 minutes a time, twice a day, six days a week, lasting for eight weeks. The observation group received ingestion training guided by the V-VST in addition to the traditional rehabilitation training methods of the control group, 10 minutes a time, three times a day, six days a week, lasting for eight weeks. …”
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Induced maturation of eel weighed 100–150 gram with PMSG, antidopamine, and 17α-methyltestosterone by Nadia Mega Aryani, Agus Oman Sudrajat, Odang Carman

“…Based on gonadal histology analysis, 2nd phase of spermatogonia development was found in P3 in week-8. The highest testosterone level was obtained by treatment P3, followed by P4, P2, and P1 in week-4. …”
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Liraglutide Decreases Liver Fat Content and Serum Fibroblast Growth Factor 21 Levels in Newly Diagnosed Overweight Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Diseas... by Xinyue Li, Xiaojuan Wu, Yumei Jia, Jing Fu, Lin Zhang, Tao Jiang, Jia Liu, Guang Wang

“…FGF21 levels decreased after the 12-week liraglutide treatment (159.6±35.7 vs. 124.2±27.8 pg/ml, P=0.006). …”
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Prevalence of dyslipidemia and its influencing factors among adult residents in Hebei province: a cross-sectional survey by Qianyu LI, Yajing CAO, Lijuan TANG, Yuhuan LIU, Xiaoying LU, Qi QI, Shifan WANG, Xiaoli LIU, Ze CUI

“…Unconditional multivariate logistic regression analysis showed that among adult residents, age ≥ 25 years, current smoking, overweight, obesity, central obesity, body fat percentage ≥ 27.2%, and basal metabolic rate ≥ 1 504 kcal were risk factors for dyslipidemia, whereas female gender, rural residence, and sedentary time of 2 – 4 hours per day were protective factors against dyslipidemia; age ≥ 25 years, college education or higher, current smoking, central obesity, and body fat percentage ≥ 37.9% were risk factors for hypercholesterolemia, whereas a basal metabolic rate of 1 199 – 1 503 kcal was a protective factor; age 25 – 64 years, current smoking, consumption of animal and poultry meat 300 – 500 g per week, overweight, obesity, central obesity, and body fat percentage ≥ 27.2% were risk factors, whereas female gender was a protective factor for hypertriglyceridemia; age ≥ 25 years, central obesity, sedentary time ≥ 2 hours per day, and body fat percentage ≥ 37.9% were risk factors, whereas basal metabolic rate 1 199 – 1 503 kcal was a protective factor for hyper-LDL-C; ethnic minority, current smoking, overweight, obesity, central obesity, physical inactivity, body fat percentage 33.0% – 37.8%, and basal metabolic rate ≥ 1 327 kcal were risk factors, whereas being female, aged 45 – 54 years, living in rural areas, drinking alcohol, consuming livestock and poultry meat > 500 g per week, and being sedentary for ≥ 2 hours per day were protective factors for hypo-HDL-C. …”
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Reactive agility training to prevent frailty in older adults – a randomized controlled trial. by Eric Lichtenstein, Martin Keller, Ralf Roth, Sebastian Ludyga, Oliver Faude

“…The AT program, conducted over a period of 16 weeks (twice per week), involved tasks that progressed in complexity and placed high demands on cognitive skills, strength, balance by applying reactive light systems. …”
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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

“…Participants will attend weekly study visits from Baseline to Week 12 and a follow-up telephone visit at Week 16. …”
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The effectiveness of digital technology-based Otago Exercise Program on balance ability, muscle strength and fall efficacy in the elderly: a systematic review and meta-analysis by Zihao He, Hua Wu, Guanggao Zhao, Yiming Zhang, Chao Li, Yachen Xing, Anjie Xu, Junchao Yang, Ronghui Wang

“…A training regimen of 12 weeks or more, with sessions occurring three or more times per week for 30 to 45 min, appears to be an effective approach for improving these outcomes based on the available evidence from the included studies. …”
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The Effects of a Red-Light Controllable Nitric Oxide Donor, NORD-1, on Erectile Dysfunction in Rats with Streptozotocin Induced Diabetes Mellitus by Yuji Hotta, Kyoya Oyama, Takuma Yoshida, Naoya Ieda, Taiki Mori, Yasuhiro Horita, Tomoya Kataoka, Yoko Furukawa-Hibi, Susumu Ohya, Hidehiko Nakagawa, Kazunori Kimura

“…Materials and Methods: Seven-week-old male Sprague-Dawley rats were used in this study. …”

Evaluating the effects of dietary glutamine on performance, carcass traits, blood biochemistry, and intestine morphology in laying quail by Ewa Tomaszewska, Kamil Drabik, Kornel Kasperek, Piotr Dobrowolski, Monika Hułas-Stasiak, Renata Pyz-Łukasik, Waldemar Paszkiewicz, Monika Ziomek, Janine Donaldson, Katarzyna Dobrowolska, Artur Burmaczuk, Justyna Batkowska, Marcin B. Arciszewski, Siemowit Muszyński

“…This study investigated the effects of dietary glutamine (Gln) supplementation on the performance, carcass characteristics, blood biochemistry, intestinal morphology, and gut microbiota of laying quail over a 12-week period, with analyses conducted after 6 and 12 weeks of supplementation. …”
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Adapting a Mobile Health App for Smoking Cessation in Black Adults With Anxiety Through an Analysis of the Mobile Anxiety Sensitivity Program Proof-of-Concept Trial: Qualitative St... by Marshall K Cheney, Adam C Alexander, Lorra Garey, Matthew W Gallagher, Emily T Hébert, Anka A Vujanovic, Krista M Kezbers, Cameron T Matoska, Michael J Zvolensky, Michael S Businelle

“…ObjectiveThis study examined the acceptability and feasibility of the MASP smartphone app following a 6-week pilot test through postintervention qualitative interviews. …”
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Effect of Body-Weight-Based Resistance Training on Balance Ability and Fear of Falling in Community-Dwelling Older Japanese Women by Zhenyue Liu, Shuji Sawada, Pengyu Deng, Hisashi Naito, Shuichi Machida

“…The LRT group participated in the exercise session twice weekly for 12 weeks, while the CON group maintained their daily routine. …”
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Long-term outcome of a treat-to-target strategy in late-onset rheumatoid arthritis with chronic lung disease: 5-year results of a prospective observational study by Manami Nomura, Takahiko Sugihara, Hiroyuki Baba, Tadashi Hosoya, Mari Kamiya, Tatsuro Ishizaki, Takumi Matsumoto, Kanae Kubo, Fumio Hirano, Masayo Kojima, Nobuyuki Miyasaka, Shinsuke Yasuda, Masayoshi Harigai

“…If patients exhibited no response according to the European League Against Rheumatism criteria at week 12 or had not achieved LDA by week 24, biological disease-modifying antirheumatic drugs (bDMARDs) were started targeting LDA. …”
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The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review by Yan Chen, Yan Chen, Jiaojiao Zhao, Jiaojiao Zhao, Yifei Wang, Yifei Wang, Long Ge, Long Ge, Joey Sum-wing Kwong, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Shuimei Sun, Songsong Tan, Xiaoqing Lin, Rui He, Wenyi Zheng, Xiaosi Li, Jiaxing Zhang

“…Primary outcomes were the all-cause mortality at week 12, and secondary outcomes included overall response rate, and incidence of adverse events (AEs) and severe adverse events (SAEs).ResultsA total of three RCTs involving 1,368 participants (four antifungals) were included. …”
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Maternal exposure to ambient temperature and risk of preterm birth in Chengdu, China, from 2017 to 2020: a cohort study by Qiqi Huang, Xiong-Fei Pan, Shijiao Yan, Zhonghan Sun, Yuwei Lai, Yixiang Ye, Jiaying Yuan, Chuanzhu Lv, Rixing Wang, Xingyue Song

“…The main exposure assessment was conducted during eight different exposure windows, including the first three months of pregnancy, 7 weeks periods during the first two trimesters, throughout pregnancy, 1-week preceding delivery, and 4 weeks preceding delivery. …”
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