Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

“…Additionally, one-third of grade ≥3 AEs on hypertriglyceridemia occurred within 1 week. The delta_FT4 (difference in FT4 from baseline) negatively correlated with TG increase at 1 week (p = 0.012) but not with low density lipoprotein cholesterol (LDL-C) increase at any week. …”
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Integrating network analysis and experimental validation to reveal the mechanism of Cuscuta chinensis lam. Extract in the treatment of IgA nephropathy by Xianlong Zhang, Mingjie Liang, Ziyang Lin, Minyi Li, Tingting Duan, Yun Han, Lanqing Meng, Mengqiu Li, Guixuan Lin, Tao Xia, Ying Lai, Boen Liang, Bingqiong Li, Minhua Li, Fengxin Kang, Quan Zhu, Zhenghai Li, Junzheng Yang

“…Sprague-Dawley rats were administered with bovine serum albumin (BSA) with a dose of 800 mg/kg−1 every other day for a period of 12 weeks to obtain IgA nephropathy model. lipopolysaccharide (LPS) was injected through the tail vein at a dose of 0.05 mg at the 6th week, 8th week, and 10th week; 0.1 mL of CCl4 and 0.3 mL of castor oil were injected subcutaneously once a week for 12 weeks; the rats were gavaged with CCLE for 6 weeks from 13th week. …”
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Epidermoid Carcinoma of the Cervix and Pregnancy. A case presentation. by Práxedes Rojas Quintana, Doris González Díaz, Carlos Pérez Velásquez

“…<p>A 25 year-old female patient with a 12 week pregnancy was presented. She was diagnosed with an ultered Pap test. …”
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Ticagrelor Associated Heart Block: The Need for Close and Continued Monitoring by Munish Sharma, Daniel A. N. Mascarenhas

“…According to the PLATO trial, ticagrelor is associated with ventricular pauses in the first week of treatment; however, these episodes were felt to be asymptomatic and nonfatal to the patient. …”
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Examining innovation in the Alps at the local scale by Philippe Bourdeau

“…The Pays des Ecrins, which hosted the 2008 Alpine Week, is an emblematic mountain region of the French Alps that has to adapt in the face of numerous endogenous and exogenous crises and changes. …”
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La junte militaire birmane confrontée au Cyclone Nargis by Marion Sabrié

“…Despite this disaster, the junta maintained the referendum about Constitution one week after.…”
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Septicemia and Aortic Valve Endocarditis due to Erysipelothrix rhusiopathiae in a Homeless Man by Dean Campbell, Mark Cowan

“…He recovered completely after aortic valve replacement and a 6-week course of intravenous ceftriaxone.…”
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Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction by Zhendong Feng, Han Xue Jiang, Huiyang Chen, Yu Ning Liu, Yahui Wang, Rui Bing Yang, Xueting Han, Chen Hui Xia, Ze Bing Zhu, Hongcai Shang, Aiming Wu, Wei Jing Liu

“…At week 4, LC3-II did not significantly increase and p62 levels significantly increased. …”
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Therapeutic Effect of High-Definition Transcranial Direct Current Stimulation Combined with Suspension Exercise Training on Lower Limb Motor Function of Stroke Patients by ZHANG Haiquan, HU Chuan, HUANG Lei, LU Wei, WANG Xin

“…The control group received conventional rehabilitation treatments such as exercise therapy and neuromuscular electrical stimulation, 25 minutes a day, once a day, 5 days a week for 8 weeks. In addition to the treatment received by the control group, the HD-tDCS group received HD-tDCS treatment, in which the primary stimulation electrodes were placed at the primary motor cortex of the hemiplegic side of the brain in the M1 area (C3/C4), and the four acceptor electrodes were placed at C1/C2, C5/C6, FC3/FC4 and CP3/CP4 area about 3.5 cm around the M1 area, respectively, with a constant current intensity of 2 mA, and a current rise and fall of 30 s, 20 minutes a time, once a day, 5 days a week for 8 weeks. …”
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Analysis of Prognostis Factors and Effect of Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease by Yiming XU, Honghua SHEN, Jingbo DU, Lei REN

“…All patients completed aerobic exercise of different intensity for 20 weeks, and postoperative life quality, treatment, and survival time of the patients were followed up for 2 years. …”
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Safety and efficacy of filgotinib in patients with rheumatoid arthritis: final results of the DARWIN 3 long-term extension study by Arthur Kavanaugh, Paul Emery, René Westhovens, Mark C Genovese, Kevin L Winthrop, Rieke Alten, Dick de Vries, Lorenzo Dagna, Patrick Verschueren, Maria Greenwald, Regina Cseuz, Robin Besuyen, Vikas Modgill, Ly Huong Le

“…Disease response assessed using non-responder imputation plateaued at LTE week 12 before slowly declining over time, with overall American College of Rheumatology (ACR)20/50/70 response rates of 26.9%/20.2%/14.7% at week 396.Conclusion Filgotinib was well tolerated in patients with RA for up to 8 years. …”
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The Chinese version of the immediate mood scaler (IMS): a study evaluating its validity, reliability, and responsiveness in patients with MDD in China by Xiongying Chen, Zizhao Feng, Nanxi Li, Le Xiao, Xu Chen, Xuequan Zhu

“…In total, 185 participants completed the retest at Week 2 which included the PHQ-9, GAD-7, and IMS. …”
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Prevention Of Breast and Endometrial cancer using Total Diet Replacement (PROBE-TDR) trial: protocol for a randomised controlled trial by Robert Clarke, Emma J Crosbie, Basil G Issa, John Belcher, Helen Clarke, Anthony Howell, Michelle Harvie, Hannah Harrison, Cheryl Lombardelli, Suzanne Krizak, Katharine Sellers, Yit Y Lim, Caroline Parkin, Shruthi Patel, Anthony J Maxwell, Julie Wisely, Sacha J Howell

“…The TDR programme includes an initial 12-week period of TDR (850 kcal/day) followed by a 40-week food-based diet, based on the nutritional principles of a Mediterranean diet, as either continued weight loss (~1500 kcal/day) or weight loss maintenance (~2000 kcal/day). …”
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Correlates of and changes in aerobic physical activity and strength training before and after the onset of COVID-19 pandemic in the UK: findings from the HEBECO study by Lion Shahab, Abigail Fisher, Phillippa Lally, Aleksandra Herbeć, Dimitra Kale, Verena Schneider

“…MVPA increased or decreased by an average of 150 min/week and 219 min/week, respectively, and MSA by 2 days/week. …”
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Effectiveness of a Web-Based Medication Education Course on Pregnant Women’s Medication Information Literacy and Decision Self-Efficacy: Randomized Controlled Trial by Suya Li, Hui-Jun Chen, Jie Zhou, Yi-Bei Zhouchen, Rong Wang, Jinyi Guo, Sharon R Redding, Yan-Qiong Ouyang

“…A total of 108 participants were randomly divided into a control group (CG), which received routine prenatal care from nurses and physicians, and an intervention group (IG), which received an additional 3-week web-based medication education course based on the theory of planned behavior as part of routine prenatal care. …”
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Performance of Culture Using a Semi-Automatic Needle as a Novel Tool for Collecting Lymph Node Samples for the Diagnosis of Canine Visceral Leishmaniasis by Artur Augusto Velho Mendes Júnior, Fabiano Borges Figueiredo, Luiz Cláudio Ferreira, Lucas Keidel, Renato Orsini Ornellas, Adilson Benedito Almeida, Fernanda Nunes Santos, Luciana de Freitas Campos Miranda, Andreza Pain Marcelino, Sandro Antonio Pereira, Rodrigo Caldas Menezes

“…Culture positivity using the different sampling techniques was 77% for necropsy (87% in the first week), 73% for FNAP (82% in the first week), and 63% for SANP (95% in the first week). …”
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The burden of generational harm due to alcohol use in Tanzania: A mixed method study of pregnant women. by Kirstin West, Alena Pauley, Mia Buono, Miriana Mikindo, Yvonne Sawe, Joseph Kilasara, Francis Sakita, Sharla Rent, Bariki Mchome, Blandina T Mmbaga, Catherine A Staton

“…This group also reported the highest weekly alcohol expenses, with 18.1% spending over 10,000 Tanzanian shillings (TZS) per week. …”
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Kinetics of IgM, IgA, IgG to SARS-CoV-2 in children with COVID-19 in Lviv region in different periods of the infectious process depending on the severity of the course and age by Maria Stasiv

“…Results and Discussion.The research findings of IgM to SARS-CoV-2 in the first week of illness revealed a median value of 0.24 [0.14; 1.39], increasing to 0.49 [0.30; 2.87] in the second week. …”
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Effect of Tiaoshen Patting Therapy Combined with Zhichan Granule on Patients with Parkinson's Disease by CAI Li, HAN Yue, WANG Taidong, GU Linyi, ZHU Kun, LIU Yi

“…The Western medicine treatment group received health education about PD and Dobasazide tablets, three times a day, seven days a week, continuous treatment for 12 weeks; the traditional Chinese and Western medicine treatment group received Zhichan granule on the basis of the Western medicine treatment group, two times a day, seven days a week, continuous treatment for 12 weeks; the combined treatment group received Tiaoshen patting therapy on the basis of the traditional Chinese and Western medicine treatment group, 30 minutes a time, one time a day, three days a week, continuous treatment for 12 weeks. …”
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Corneal Backscatter Analysis by In Vivo Confocal Microscopy: Fellow Eye Comparison of Small Incision Lenticule Extraction and Femtosecond Laser-Assisted LASIK by Alper Agca, Engin Bilge Ozgurhan, Yusuf Yildirim, Kadir Ilker Cankaya, Nimet Burcu Guleryuz, Zeynep Alkin, Abdullah Ozkaya, Ahmet Demirok, Omer Faruk Yilmaz

“…The mean backscattered light intensity (LI) at all measured depths and the maximum backscattered LI were higher in the SMILE group than the femto-LASIK group at all postoperative visits. LI differences at 1 week and 1- and 3-month visits were statistically significant (P<0,05). …”
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