Shaping Treatment Expectation to Optimize Efficacy of Interleukin 17A Antagonist Secukinumab in Psoriasis Patients by Hölsken S, Krefting F, Mühlhaus S, Bese D, Schedlowski M, Sondermann W

“…We evaluated skin symptoms using the Psoriasis Area and Severity Index (PASI), the Dermatology Life Quality Index (DLQI), perceived itch, mood and plasma IL-17A levels at baseline and at 1, 2, 3, 4, 8, 12, and 16 weeks post intervention.Results: The study included N = 120 patients (average age = 45.78 years, 34% female). …”
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Thrombophilia screening in women with recurrent first trimester miscarriage: is it time to stop testing? – a cohort study and systematic review of the literature by Hassan Shehata, Ranjit Akolekar, Amanda Ali, Mariane Silva-Edge, Shahla Haroon, Abdullatif Elfituri, Radhika Viswanatha, Haider Jan

“…Tests for LA/ACL were performed a minimum of 12 weeks apart thus meeting the revised Sapporo criteria for a diagnosis of antiphospholipid syndrome.Conclusion The findings of our study demonstrate that the prevalence of inherited thrombophilia is similar in women with RM to that in the general population. …”
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Long-Term Safety and Effectiveness of Dimethyl Fumarate in Patients with Multiple Sclerosis Treated in Routine Medical Practice: Final Analysis of the ESTEEM Study by Krupa Shah Pandey, Kathryn Giles, Konstantin Balashov, Richard Macdonell, Jörg Windsheimer, Mikel Martinez, Ivan Božin, Stephanie Raynaud, Matthew Scaramozza, Oksana Mokliatchouk, Zhaonan Sun, Nicholas Belviso, Yayoi Sato, Xiaochen Lin, Annette Okai

“…The estimated proportion of patients free from confirmed disability progression sustained over 48 weeks was 87.0% at month 60. Mean scores for physical and psychological impact, fatigue, health, and productivity remained stable over 5 years. …”
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Pregabalin vs. gabapentin in the treatment of neuropathic pain: a comprehensive systematic review and meta-analysis of effectiveness and safety by Víctor Mayoral, Rafael Galvez, Marta Ferrándiz, Xoán Miguéns Vázquez, Carlos Cordero-García, Antonio Alcántara Montero, Concepción Pérez, María Pérez-Páramo

“…Pregabalin showed superior results compared to gabapentin in the Visual Analog Scale (VAS) at various time intervals up to 12–14 weeks (SMD −0.47, 95% CI −0.74 to −0.19). The pregabalin group also had significant improvements in SF-12/SF-36/EQ-5D scores (SMD 0.39, 95% CI 0.11–0.68) and experienced more days with no/mild pain (MD 9.00, 95% CI 8.93–9.07) and fewer days with severe pain (MD −3.00, 95% CI −4.96 to −1.04). …”
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Impact of pulmonary yoga module on lung capacity of COVID-19 adult survivors by Adarsh Tomar, Sudhanshu Verma

“…The simple random sampling technique applied for the selection procedure and expulsion standard is 10%. OUTCOME: After 8 weeks of yoga intervention (selected yogic practice) on day 60th, posttest data were taken and assessed on different significance levels (α). …”
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Subcutaneous Fat Obesity in a High Body Mass Index Donor Is Not a Contraindication to Living Donor Hepatectomy by Hirak Pahari, Amey Sonavane, Amruth Raj, Anup Kumar Agrawal, Ambreen Sawant, Deepak Kumar Gupta, Amit Gharat, Vikram Raut

“…The donor was discharged on POD-6 and recipient was discharged on POD-15. At 3 weeks of follow-up, the donor’s wound is clean and well-healed, and she is already back to doing her daily life activities without any pain with normal laboratory parameters. …”
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Effectiveness of mobile health for exercise promotion on cardiorespiratory fitness after a cancer diagnosis: A systematic review and meta‐analysis by Megan E. Gregory, Weidan Cao, Saurabh Rahurkar, Fadi Haroun, James C. Stock, Sanam M. Ghazi, Daniel Addison

“…Interventions included mobile apps (k = 6), smartwatches (k = 2), or a smartwatch plus a supplemental web/mobile/tablet app (k = 1); median duration of mHealth‐use was 12 weeks. Seven (n = 341) fit criteria for meta‐analysis. mHealth was associated with improved cardiorespiratory fitness (d = 0.33; 95% CI = 0.07–0.60) compared to a control group. …”
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External validation and revision of the Lafontaine criteria for unstable distal radius fractures: a retrospective study by Pornpanit Dissaneewate, Phatklao Thanavirun, Yanin Tangjaroenpaisan, Kantapon Dissaneewate

“…Patients who underwent immediate surgery, were lost to follow-up before 4 weeks, or had unacceptable alignment after reduction were excluded. …”
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Comparing responses to public health and industry-funded alcohol harm reduction advertisements: an experimental study by Sarah J Durkin, Melanie A Wakefield, Emily Brennan, Michael D Slater, Simone Pettigrew, Danielle A J M Schoenaker, Kimberley Dunstone, Helen G Dixon

“…We hypothesised that, on average, SAPRO advertisements would be less effective at generating motivation (H1) and intentions to reduce alcohol consumption (H2) but more effective at generating positive perceptions of people who drink (H3).Design Online experiment with random assignment to condition.Participants 2923 Australian adult weekly drinkers (49% high-risk drinkers) recruited from an opt-in online panel.Interventions Participants viewed 3 of 83 advertisements developed by PH agencies (n=2174) or 3 of 28 advertisements developed by SAPROs (n=749).Primary outcome measures Participants reported their motivation to reduce the amount of alcohol consumed; behave responsibly and/or not get drunk; and limit their drinking around/never supply to minors, as well as intentions to avoid drinking alcohol completely; reduce the number of drinking occasions; and reduce the amount of alcohol consumed per occasion. …”
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Guillain-Barré syndrome following falciparum malaria infection: a case report by Molla Asnake Kebede, Alemayehu Beharu Tekle, Misikir Alemu Eshetu, Erkyehun Pawlos Shash, Melaku Tsediew Berhanu, Elias Tabiet Ahmed, Hashime Meketa Negatie

“…After extensive workup, the patient was managed with consideration of Guillain-Barré Syndrome (GBS), and she made a complete recovery after 12 weeks. Discussion Guillain-Barré Syndrome (GBS) is an acute paralytic illness often triggered by infections, particularly viral ones. …”
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Travoprost Intracameral Implant in Eyes with Glaucoma or Ocular Hypertension: Early Short-Term Real-World Outcomes by Teymoorian S, Kaur J

“…One eye was reported to have mild iritis at 1– 2 weeks postoperatively, and was treated with a topical prednisolone acetate taper. …”
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Association between the atherogenic index of plasma and non-alcoholic fatty liver disease in Korean pregnant women: secondary analysis of a prospective cohort study by Rong Shuai, Yuxing He, Dongqian Yang, Yingying Zhang, Li Zhang

“…BackgroundRecent studies have shown an association between atherogenic index of plasma (AIP) and nonalcoholic fatty liver disease (NAFLD), but the association in a population of pregnant women remains unclear.ObjectivesOur study aimed to examine the association between AIP and NAFLD in pregnant Korean women.MethodsOur study used publicly available data from Korea, which recruited singleton pregnant women between November 2014 and September 2016 who were at 10–14 weeks of gestation. The presence of NAFLD was diagnosed by liver ultrasound. …”
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Blood pressure control with active ultrafiltration measures and without antihypertensives is essential for survival in hemodiafiltration and hemodialysis programs for patients with... by Franklin Geovany Mora-Bravo, Pamela Tatiana Morales Torres, Nelson Rojas Campoverde, Guillermina Lucía Blum Carcelen, Juan Cristobal Santacruz Mancheno, Ángel Cristóbal Santacruz Tipanta, Hector Perez-Grovas, Willan Patricio Robles Abarca

“…Weight was optimized with POC-DW for eight weeks. In Group 1, patients whose use of antihypertensive drugs was not required to control systolic blood pressure with a value less than 150 mmHg predialysis, less than 130 mmHg postdialysis, and a peridialytic blood pressure (defined as post-HD minus pre-HD SBP) between 0 and − 20 mmHg were analyzed. …”
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Premalignant features of the prostate can be ameliorated by Uvaria chamae root extract: Modeling prostate cancer with cadmium and alternative treatment option in adult Wistar rats by Edem GD, Sakpa CL, Ezeuko VC

“…Group 1 received water and diet alone, group 2 received 3mg/kg of cadmium alone once weekly for 28days. Group 3-6 received 3mg/kg of cadmium for 28days followed by 150mg/kg of casodex, 2500mg/kg, 1500mg/kg and 1000mg/kg of Uvaria chamae root extract respectively for 28days. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Case presentation A 26-year-old patient with a history of four pregnancies and one delivery (P4G1) presented at 30 weeks and 2 days of gestation with vaginal fluid leakage and fetal growth restriction detected by ultrasound at a different hospital. …”
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Xiaohua Funing decoction ameliorates non-alcoholic fatty liver disease by modulating the gut microbiota and bile acids by Jindong Zhao, Jindong Zhao, Yan Li

“…There were eight rats in each group, and the treatment lasted for 12 weeks. Furthermore, metagenomic sequencing and BA metabolomic analyses were performed.ResultsCompared to the Con group, the Mod group presented significant differences in body and liver weights; serum total cholesterol (TC) and triglyceride (TG) levels; and liver TG, TC, and bile salt hydrolase levels (p < 0.05 or p < 0.01). …”
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The association between self-reported total gestational weight gain by pre-pregnancy body mass index and moderate to late preterm birth by Alexandra M. Palumbo, Giulia M. Muraca, Anne Fuller, Charles D.G. Keown-Stoneman, Catherine S. Birken, Jonathon L. Maguire, Laura N. Anderson, on behalf of the TARGet Kids! collaboration

“…Objectives We examined the associations between categorical and continuous total GWG and moderate to late preterm birth (32-<37 weeks), and evaluated differences in these associations by pre-pregnancy BMI. …”
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Assessment of bacterial positivity rate changes in anesthesia machine internal circuits within recovery rooms and associated risk factors by Shuxiao Zhang, Jingwu Ge, Xuelong Zhou, Yanhong Ji, Junjie Hong, Wensu Xu, Tonglai Li

“…The internal circuits of the anesthesia machines were disinfected every two weeks. Samples were obtained from the internal circuits on the 3rd, 5th, 7th, 10th, 12th, and 14th day following disinfection for bacterial culture. …”
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The newborn behavioural observations (NBO) system embedded in routine postpartum care in at-risk families in Iceland: a randomised controlled trial by Lisbeth Valla, Kari Slinning, Tore Wentzel-Larsen, Gun-Mette Røsand, Stefanía Birna Arnardóttir

“…Maternal confidence was measured using a parent questionnaire (covering learning outcomes relating to the infant’s communicative signals and maternal confidence) administered after each home visit in weeks 2, 3 and 4 postpartum. At 4 months infant age, a free-play situation involving mother-infant interaction was video-recorded in the participants’ homes and coded using the Emotional Availability Scale (EAS). …”
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Rehabilitation Effects of Traditional Chinese Medicine Hot Pressing on Female Patients with Stress Urinary Incontinence by HUANG Huirong, LIU Qinyu, YU Zhenling, WU Cuijuan, XUE Jialu, QIU Zhiqin, YU Mengxia

“…Both groups were treated for 4 weeks. The leakage of urine (1-hour pad test) and Urogenital Distress Inventory (UDI-6) score before and after treatment and the Incontinence Quality of Life Questionnaire (I-QOL) scores before and after treatment and 1 month follow-up were evaluated.Results1) The urine leakage of 1-hour pad test in both groups after treatment was less than before treatment, and the difference was statistically significant (<italic>P</italic>&lt;0.05). …”
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