Non-Immersive Virtual Reality Exercise Can Increase Exercise in Older Adults Living in the Community and in Long-Term Care: A Randomized Controlled Trial by Sheehy L, Bharadwaj L, Nissen KA, Estey JL

“…Non-immersive virtual reality consisted of 20– 30 minutes of customized, gamified exercises for balance, stepping, strengthening, and aerobic conditioning, performed 3– 5x/week for 8 weeks. Outcomes were measured before the intervention, immediately after, and 1 month later. …”
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Efficacy and safety of everolimus for patients with focal cortical dysplasia type 2 by Se Hee Kim, Hoon‐Chul Kang, Yun Ho Roh, Jongsung Hahn, Kyung Lok Min, Seok‐Jin Lee, Donghwa Yang, Han Som Choi, Soyoung Park, Jeong Ho Lee, Sang‐Guk Lee, Se Hoon Kim, Min Jung Chang, Heung Dong Kim

“…The trial included a 4‐week baseline phase, two 12‐week core phases, and a 29‐week extension phase. …”
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Risankizumab Versus Secukinumab: A Real-World Efficacy and Cost per Responder Comparison in Patients With Psoriasis in Italy by Federico Pirro, Giacomo Caldarola, Nicoletta Bernardini, Maria Grazia Celeste, Annunziata Dattola, Eleonora De Luca, Marco Galluzzo, Domenico Giordano, Chiara Izzi, Giulia Maretti, Lorenzo Marcelli, Roberto Ravasio, Antonio Giovanni Richetta, Nevena Skroza, Marina Talamonti, Arianna Zangrilli, Luca Bianchi, Giovanni Pellacani, Severino Persechino, Concetta Potenza, Ketty Peris, Clara De Simone

“…The cost per responder at week 16 and 52 was adopted as a cost-effectiveness indicator. …”
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A Comparative Evaluation of the Efficacy of Two Novel Desensitising Dentifrices by Ashley P. Barlow, Jane He, Cindy Tian, Peter Jeffery, Stephen C. Mason, Bao-Jun Tai, Han Jiang, Gareth D. Rees, Min Quan Du

“…Subjects (N=110), stratified into two groups (N=55), brushed twice-daily for 60 s, over an 8-week period. Sensitivity status, compliance, and safety were determined at 1, 2, 4, and 8 weeks. …”
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Improvement of Fatigue in Patients with Ankylosing Spondylitis Receiving Tofacitinib: Analyses of a Phase 3 Randomized Controlled Trial by Laure Gossec, Jessica A. Walsh, Raj Sengupta, Andrew G. Bushmakin, Joseph C. Cappelleri, Arne Yndestad, Oluwaseyi Dina, David Cella

“…The rapidity of improvement was assessed by time-to-event analyses (nonparametric Kaplan–Meier models); initial improvement events (i.e., time to first week of FACIT-F improvement) and stable improvement events (i.e., time to first week of FACIT-F improvement, sustained to 16 weeks) were examined. …”
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Relationship between psychological empowerment, physical activity enjoyment, and response to a HIIT Program in physically inactive young women: a prospective multicentre study by Irene Ferrando-Terradez, Rodrigo Núñez-Cortés, Laura López-Bueno, Enrique Alcántara, Joaquín Calatayud, José Casaña, Ivana Parčina, Lirios Dueñas

“…Outcome measures included physical activity levels (MET-min/week), muscular endurance (plank test), and sleep quality through the Pittsburgh Sleep Quality Index (PSQI). …”
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The impact of universal mental health screening on stigma in primary schools by Annabel Songco, Deanna A. Francis, Emma A. McDermott, Chloe Y. S. Lim, Abigail Allsop, Joseph Croguennec, Gemma Sicouri, Andrew Mackinnon, Jennifer L. Hudson

“…A sample of 798 children (8 to 13 years; Mage = 10.29) completed assessments at baseline, 6-week, and 12-week follow-ups. Results Significant time-by-group interaction effects were present, indicating differing changes in mental health stigma between groups. …”
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Valerenic acid ameliorates amphetamine-related neurotoxicity by improving hypothalamus tyrosine hydroxylase and histamine-N-methyl transferase enzymes by Khaled M.M. Koriem, Ammar H.A. Naiem

“…METH-treated, VA (5 mg/kg) prior to METH-treated, and VA (10 mg/kg) before METH-treated groups: normal rats were oral administrated with METH (2.5 mg/kg), 3 days/week for 3 weeks, where the last two groups were oral administrated daily during four weeks at 5 mg/kg and 10 mg/kg VA, starting one week prior to METH administration. …”
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High-dose glucocorticoid treatment vs. glucocorticoid replacement in immune checkpoint inhibitor associated hypophysitis (CORTICI): an open, randomised controlled trial by Verena Theiler-Schwetz, Christian Trummer, Lisa Schmitt, Angelika Terbuch, Barbara Obermayer-Pietsch, Erika Richtig, Stefan Pilz

“…This is the first randomised study to evaluate whether hormonal recovery differs in patients treated with high-dose glucocorticoids versus glucocorticoid replacement therapy.Design/Methods In this single-centre, open, randomised controlled study, patients with ICI associated hypophysitis were randomised 1:1 to high-dose glucocorticoid treatment (1 mg/kg of prednisolone for two weeks, followed by tapering until week 7 and a switch to hydrocortisone 20 mg total daily dose in week 8) or glucocorticoid replacement therapy (hydrocortisone 20 mg total daily dose) over 8 weeks. …”
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Association of vaginal oestradiol and the rate of breast cancer in Denmark: registry based, case-control study, nested in a nationwide cohort by Christian Torp-Pedersen, Lina Steinrud Mørch, Nelsan Pourhadi, Amani Meaidi, Ellen Christine Løkkegaard

“…Results were similar in women who had long term use (≥four years) and with high intensity of use (>50-70 micrograms per week) with an adjusted hazard ratio 0.93 (95% confidence interval 0.81 to 1.08).Conclusions Use of vaginal oestradiol tablets was not associated with increased breast cancer rate compared with never-use. …”
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The Effect of Zinc Supplementation on Glycemic, Weight, and Blood Pressure Control in Patients With Type 2 Diabetes Mellitus: A Double‐Blind Randomized Controlled Trial by Mehrab Sayadi, Sara Javadpour Nowbandegani, Fatemeh Balaghi Inalou, Bahman Nazemzadegan, Shirzad Javidi Alsaadi, Mohammadreza Eskandari, Matin Sepehrinia

“…Results After 12 weeks of follow‐up, 72 patients completed the study. …”
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Comparison of dairy production based on feed of Pennisetum sp., Pennisetum purpureum and CIAT 36087 by Noel Ernesto Blanco–Roa, Hernaldo Ramón Novoa–Novoa, Eveling Cristina Berríos, Omar Alfredo Soto–Gutiérrez, Carlos Alberto Zúniga–González, Silvio Javier Sáenz–Rojas, José de Jesús Nuñez–Rodriguez

“…Daily milk production for each cow was monitored and recorded over the six–week period. Highly significant differences (P<0.01) were observed among the three studied groups from the second week onward. …”
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Efficacy and Safety of Transdermal Buprenorphine versus Oral Tramadol/Acetaminophen in Patients with Persistent Postoperative Pain after Spinal Surgery by Jae Hyup Lee, Jin-Hyok Kim, Jin-Hwan Kim, Hak-Sun Kim, Woo-Kie Min, Ye-Soo Park, Kyu-Yeol Lee, Jung-Hee Lee

“…Patients received once-weekly BTDS (n=47; 5 μg/h titrated to 20 μg/h) or twice-daily TA (n=40; tramadol 37.5 mg/acetaminophen 325 mg, one tablet titrated to 4 tablets) for 6 weeks. …”
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Risk factors for early periventricular intraventricular hemorrhage in extremely low birth weight infants: a retrospective study by Yueju Cai, Yongjiang Jiang, Ping Wang, Xiaopeng Zhao, Yanyan Song, Xiaolan Li

“…Severe IVH was more prevalent in the lower gestational age groups: 40.0% in infants at 23 + 1 to 26 weeks, 10.7% in infants at 26 + 1 to 28 weeks, and 1.4% in infants at 28 + 1 to 32 weeks (p < 0.001).Logistic regression analysis revealed two independent risk factors: failure to withdraw invasive ventilation within the first week (OR = 3.276, 95% CI = 1.465–7.324, p = 0.004) and the use of vasoactive drugs within the first week (OR = 2.112, 95% CI = 1.002–4.451, p = 0.049). …”
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Within-hospital Temporal Clustering of Postoperative Complications and Implications for Safety Monitoring and Benchmarking Using ACS-NSQIP Data by Mark E. Cohen, PhD, Yaoming Liu, PhD, Clifford Y. Ko, MD, MS, MSHS, FACS, Bruce L. Hall, MD, PhD, MBA, FACS

“…The number of clusters dropped after adjustment for linear trend, day-of-week, and season (0.31–0.24; P = 0.012; 0.85–0.80; P = 0.034; and 0.51–0.36; P < 0.001; using paired t tests) for mortality, morbidity, and SSI, respectively. …”
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Assessment of students’ ability to represent determinants of health and health systems science content on concept maps in a pre-clerkship curriculum by Tovah Tripp, Miriam Hoffman, Mitchell Miller, Joshua S. Josephs

“…This course includes a Monday discussion of a patient case and a Friday small group session includes concept mapping of the week's basic, clinical, and health systems science (HSS) content. …”
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Compositional Characteristics and Antioxidant Activity of Edible Rose Flowers and Their Effect on Phenolic Urinary Excretion by Andrea Devecchi, Sonia Demasi, Francesca Saba, Rosalba Rosato, Roberto Gambino, Valentina Ponzo, Antonella De Francesco, Paola Massarenti, Simona Bo, Valentina Scariot

“…Rose petals were picked fresh once a week for three weeks, showing significantly increasing values of total phenolic content, total anthocyanin content, and antioxidant activity (measured as ferric reducing antioxidant power (FRAP) and as DPPH • and ABTS •+ scavenging activities) from the first to the third week. …”
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Laserpuncture Shooting Duration Effect at the Growth Point on the Weight Gain and Growth Rate of Male Japanese quail (Coturnix coturnix japonica) by Aida Zharah, Sri Hidanah, Yeni Dhamayanti, Sunaryo Hadi Warsito, R Tatang Santanu Adikara, Gracia Angelina Hendarti

“…The result of the research were obtained from weighing the body weight every week and then substracting the results from the previous week. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…The clinical severity of different variants was assessed in relation to patient sex, age, clinical classification, and vaccination status.ResultsBetween Week 1 of 2023 and Week 11 of 2024, a total of 5,965 complete SARS-CoV-2 genome sequences were obtained, including 3,004 male (50.36%) and 2,961 female (49.64%) cases. …”
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Characteristics of Slovenian Adults in Community-Based Whole-Food Plant-Based Lifestyle Program by Boštjan Jakše, Barbara Jakše, Stanislav Pinter, Jernej Pajek, Nataša Fidler Mis

“…The participants had an average BMI of 23.9 kg/m2 (SD: 3.8 kg/m2) and an average BF% of 22.3% (SD: 7.3%), were physically very active, with an average Long International Physical Activity Questionnaire (L-IPAQ) score of 5541.2 metabolic equivalents (METs) min/week (SD: 4677.0 METs min/week), having good sleep quality, with an average Pittsburgh Sleep Quality Index (PSQI) score of 2.7 (SD: 1.8), perceiving low stress, and with an average Perceived Stress Questionnaire (PSQ) score of 0.29 (SD: 0.1). …”
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