Treatment Efficacy and Compliance in Patients with Diabetic Macular Edema Treated with Ranibizumab in a Real-Life Setting by Anne-Laurence Best, Franck Fajnkuchen, Sylvia Nghiem-Buffet, Typhaine Grenet, Gabriel Quentel, Corinne Delahaye-Mazza, Salomon Y. Cohen, Audrey Giocanti-Aurégan

“…Patients were monitored every 4 weeks for visual acuity (VA) and central retinal thickness (CRT) by SD-OCT. …”
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The Feasibility of Telephone-delivered Self-management Intervention in Multiple Sclerosis by Mozaffar Hosseininezhad, Sajjad Saadat, Fatemeh Younesi Rostami, Roghaye Zare, Ali Bonyad, Masoumeh Qanbary Joopish, Alia saberi, Fateme Shafaee

“…The intervention was delivered in 8 weekly sessions. The MS self-management scale–revised (MSSM-R) and the short-form health survey (SF-36) were used to collect study data. …”
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Real-World Efficacy and Safety of Avelumab Plus Axitinib in Metastatic Renal Cell Carcinoma: Results from the Ambispective RAVE-Renal Study by Ilya Tsimafeyeu, Vyacheslav Chubenko, Olga Baklanova, Alexey Kalpinskiy, Sufia Safina, Andrei Lebedinets, Vladislav Petkau, Elvira Parsadanova, Maria Turganova, Aleksei Shkurat, Natalia Tovbik, Elena Tkacheva, Yulia Anzhiganova, Olga Novikova, Varvara Bragina, Ruslan Zukov, Rashida Orlova

“…Patients received avelumab (800 mg intravenously every 2 weeks) plus axitinib (5 mg orally twice daily). The primary endpoints were median progression-free survival (PFS) and objective response rate (ORR). …”
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Incidence of hyperkalemia RAASi and SGLT-2i treatment in individuals with diabetic kidney disease: a systematic review and network meta-analysis by Yahui Yuan, Yahui Yuan, Yahui Yuan, Chun Chen, Yuping Lin, Yehao Luo, Yehao Luo, Yehao Luo, Zhaojun Yang, Zhaojun Yang, Zhaojun Yang, Jingyi Guo, Jingyi Guo, Jingyi Guo, Qiaoyun Liu, Qiaoyun Liu, Qiaoyun Liu, Lu Sun, Guanjie Fan, Guanjie Fan, Guanjie Fan

“…Relevant randomized controlled trials (RCT) included adults with DKD who were treated with SGLT-2i and RAASi or their combination, with a minimum follow-up duration of 12 weeks. The primary outcomes assessed were the incidence of hyperkalemia and serum potassium levels were the primary outcomes assessed. …”
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The histological development of the fetal human inferior colliculus during the second trimester by Reetuparna Nanda, Mihail Bota, Jaikishan Jayakumar, Jaikishan Jayakumar, Suresh S, S. Lata, E. Harish Kumar, Chitra Srinivasan, Sudha Vasudevan, Kumutha Jayaraman, Mohanasankar Sivaprakasam, Mohanasankar Sivaprakasam, Mohanasankar Sivaprakasam, Richa Verma

“…In this paper we first systematically describe the histological development of the human fetal IC and its subparts in five stages of the second trimester of pregnancy: 15 gestation weeks (GW), 18 GW, 21 GW, 24 GW, and 27 GW. We 3D reconstruct and calculate the volumetric growth of IC from one stage to another, which increases from 12.85 mm3 at 15 GW to 34.27 mm3 at 27 GW in the left hemisphere. …”
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Wenxin Granules Influence the TGFβ-P38/JNK MAPK Signaling Pathway and Attenuate the Collagen Deposition in the Left Ventricle of Myocardial Infarction Rats by Ya Huang, Aiming Wu, Lixia Lou, Dongmei Zhang, Bo Nie, Yizhou Zhao, Keke Liu, Mingjing Zhao, Hongcai Shang

“…Gavage was given once a day for 4 weeks. The changes of cardiac hemodynamics were detected by the catheter method, morphological changes were observed by HE staining, and myocardial tissue collagen volume was counted by Immunohistochemistry combined with Masson staining, and the expression of inflammatory TGFβ-p38/JNK MAPK signal pathway markers was detected by Western blot. …”
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Video-feedback intervention for promoting social engagement in children with neurodevelopmental disabilities by Rosario Montirosso, Serena Micheletti, Camilla Pisoni, Eleonora Mascheroni, Elisa Scarano, Elisa Scarano, Cecilia Naboni, Elisa Rosa, Annalisa Castagna, Margherita Bonino, Elisa Fazzi, Elisa Fazzi, Simona Orcesi, Simona Orcesi

“…The VFI was administered over 6 weeks, with each session focusing on improving parents’ developmental supporting behaviors and enhancing the quality of parent–child interactions. …”
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Combined use of zoophytophagous mirids for sustainable biological protection of greenhouse tomato crops by Kouassi A. J. Konan, Coline C. Jaworski, Lucie S. Monticelli, Mnqobi Zuma, Roger Boll, Marie-France N. Kouadio, Thibaud Martin, Benjamin Gard, Roselyne Souriau, Anne-Violette Lavoir, Nicolas Desneux

“…In this study, we tested the effect of combining N. tenuis with M. pygmaeus (at two densities: 10 and 15 individuals per plant) and with or without D. errans (five individuals per plant) on the abundance of all insects (predators and pests) for 8 weeks. We also measured leaf damage by T. absoluta and plant and flower damage (necrotic rings, flower abortion rate) by N. tenuis. …”
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Safety and Efficacy of Topical Lotilaner Ophthalmic Solution 0.25% for the Treatment of Demodex Blepharitis: A Pilot Study by Roberto Gonzalez-Salinas, Elizabeth Yeu, Mark Holdbrook, Stephanie N. Baba, Juan Carlos Ceballos, Martha Massaro-Corredor, Claudia Corredor-Ortega, Nallely Ramos-Betancourt, Hugo Quiroz-Mercado

“…Topical lotilaner ophthalmic solution, 0.25% for 4 weeks, showed promising efficacy for the treatment of Demodex blepharitis. …”
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Pomegranate peel powder and extract improved weight control, lipid metabolism and gut microbiota in hamsters fed with standard american diets by Xingzhu Wu, Wallace Yokoyama, Yuqing Tan, Glenn Bartley, Ling Chen, James Pan, Priscila Alves Buongiorno, Jose Berrios, Tara McHugh, Zhongli Pan

“…Hamsters were fed either the HF, or the HF diet supplemented with 2.5 % or 5 % PPE (LE and HE, respectively), or 5 % or 10 % PPP (low-peel (LP) and high-peel (HP), respectively. After 4 weeks of feeding, hamsters gained 16.10- 33.82 g of weight and the feeding efficacy ranged from 0.10 to 0.18. …”
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Effectiveness of small-sided games on change of direction speed in youth soccer players: a systematic review and meta-analysis by Ioan Neag, Ion Mihaila, Leonard Julien Fleancu, Alexandru Acsinte, Corina Daniela Popescu, Maura Stancu, Vladimir Potop, Gabriel Trandafirescu, Ilie Mihai

“…Inclusion criteria: healthy soccer players aged 6–19, SSG training programs of at least 4 weeks, and a control group. Data were assessed using the PEDro scale, and a meta-analysis was conducted using Hedges’s g ES. …”
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Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration by Jan Studnička, Eva Rencová, Milan Bláha, Pavel Rozsíval, Miriam Lánská, Vladimír Bláha, Jan Němčanský, Hana Langrová

“…Each treated patient received a series of 8 sessions of rheohaemapheresis of 1.5 plasma volumes within 10 weeks. We measured the drusenoid pigment epithelium detachment (DPED), best-corrected visual acuity (BCVA), electroretinography (ERG), and rheological parameters. …”
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Can the 3rd Hour Value of 100 g Oral Glucose Tolerance Test Be Ignored in the Diagnosis of Gestational Diabetes Mellitus? by Mehmet Metin Altay, Serdinç Özdoğan, Aytaç Tohma, Sertaç Esin, Okyar Erol, Orhan Gelişen, Melih Akkuş, Sinan Karadeniz

“…STUDY DESIGN: During the first 8 months of 2010, 6909 patients between 24 and 28 weeks’ of gestation were screened with 50 g glucose challenge test and 140 mg/dl or higher plasma glucose levels were further evaluated with 100 g OGTT to diagnose gestational diabetes mellitus (GDM). 1195 patients’ test results were acquired for this retrospective study. …”
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Health-related quality of life in children born preterm at school age: the mediating role of social support and maternal stress by Melissa Liher Martínez-Shaw, Melissa Liher Martínez-Shaw, Kari Anne I. Evensen, Kari Anne I. Evensen, Kari Anne I. Evensen, Sandra Melero, Sandra Melero, Yolanda Sánchez-Sandoval, Yolanda Sánchez-Sandoval

“…Research on health-related quality of life (HRQoL) of school-aged children born preterm (< 37 weeks of gestational age) is scarce and there are few studies examining the relationship with medical and family factors. …”
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Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization by Qi Sun, Xin-Yu Nan, Hui Wang, Shuo Pan, Gang Ji, Ya-Feng Guo, Ya-Heng Zhao, Gao-Cen Li, Shao-Shi Guo, Lu-Feng Lin, Yu-Jie Jin, Xue Li Zhang, Chang-Cheng Liu, Guo-Bin Liu

“…Female mice at the age of 12 weeks were intraperitoneally injected with different concentrations of PD (20 and 40 mg/kg). …”
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Yiqi Fumai Lyophilized injection protects cardiac contractility in a rat model of heart failure with reduced ejection fraction by modulating SERCA2 by Yongwei Nie, Lu Chen, Yanxin Zhang, Yuqing Yao, Zizhuo Xue, Na Guo, Meixiu Wan, Zhi Li, Chunhua Liu, Dekun Li, Aichun Ju

“…YQFM was administered via intravenous injection for two weeks. Cardiac contractility was evaluated using echocardiography. …”
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Impact of dietary Spirulina on performance, antioxidant status, carcass traits and pathological alteration in broilers exposed to ochratoxin A stress by Ayman S. Salah, Mahmoud S. El-Tarabany, Marwa Mostafa, Rania Samir Zaki, Mahmoud M. Azzam, Omnia I. El Euony, Mahmoud Alagawany, Antonia Lestingi, Ahmed A. Elolimy, Mahmoud Madkour, Ahmed Fotouh

“…The duration of this study was six weeks, during which the experimental groups were organized as follows: G1 consumed a basal diet (control), G2 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet, G3 consumed a basal diet treated with Spirulina platensis at a level of 1 g/kg of diet, G4 consumed a basal diet treated with OTA at a level of 1 mg/kg of diet and Spirulina platensis at a level of 1 g/kg diet.Results and discussionThe results illustrated that OTA-contaminated feed resulted in a significant elevation in total cholesterol, triglyceride, low- and very low density lipoprotein, and malondialdehyde, along with a significant reduction in antioxidant status and immunological response. …”
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Beneficial Effect of Fenofibrate in Combination with Silymarin on Parameters of Hereditary Hypertriglyceridemia-Induced Disorders in an Animal Model of Metabolic Syndrome by Jan Soukop, Ludmila Kazdová, Martina Hüttl, Hana Malínská, Irena Marková, Olena Oliyarnyk, Denisa Miklánková, Soňa Gurská, Zuzana Rácová, Martin Poruba, Rostislav Večeřa

“…<b>Results:</b> Fenofibrate treatment (100 mg/kg BW/day for four weeks) significantly decreased serum levels of triglyceride, (−77%) and free fatty acids (−29%), the hepatic accumulation of triglycerides, and the expression of genes encoding transcription factors involved in lipid metabolism (Srebf2, Nr1h4. …”
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Expression of lipid metabolism- related genes, body composition and inflammation: Effects of sodium butyrate supplementation in subjects with obesity by Parichehr Amiri, Seyed Ahmad Hosseini, Maryam Saghafi-Asl, Amin Akbari-Naserkiadeh, Seyedeh Asal Jenani Zavieh, Sara Arefhosseini, Samira Asghari, Neda Roshanravan

“…Fifty obese subjects were randomly allocated into either NaBu (600 mg/day) or placebo (carboxymethyl cellulose 600 mg/day) group along with hypocaloric diet for 8 weeks. At the end of the trial, the mRNA expression levels of adiponectin receptor-1, adiponectin receptor-2 and uncoupling protein-3, significantly increased in NaBu group to almost two-fold higher levels, compared with placebo group (p = 0.030, p = 0.030 and p = 0.010, respectively). …”
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A case of central diabetes insipidus after COVID-19 as a probable diagnosis of lymphocytic infundibulo-neurohypophysitis with positive anti-rabphilin-3A antibodies with review of l... by Yuka Natsuki, Yuki Nagata, Toshiki Nagasaki, Mari Morimoto, Norikazu Toi, Masafumi Kurajoh, Tomoaki Morioka, Tetsuo Shoji, Yasuo Imanishi, Naoko Iwata, Haruki Fujisawa, Atsushi Suzuki, Yoshihisa Sugimura, Masanori Emoto

“…We report a 49-year-old healthy woman who developed rapid onset of polydipsia and polyuria three weeks after COVID-19. Laboratory tests indicated low urine osmolarity and increased serum osmolarity, and antidiuretic hormone (ADH) was undetectable. …”
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