Effect of Rosiglitazone and Insulin Combination Therapy on Inflammation Parameters and Adipocytokine Levels in Patients with Type 1 DM by Metin Guclu, Ozen Oz Gul, Soner Cander, Oguzkaan Unal, Guven Ozkaya, Emre Sarandol, Canan Ersoy

“…A total of 61 adults with type 1 DM were randomly and prospectively assigned in open-label fashion to take insulin and rosiglitazone 4 mg/day (n=30) or insulin alone (n=31) for a period of 18 weeks while undergoing insulin therapy without acute metabolic complications. …”
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Prednisolone pharmacokinetics in dogs with protein‐losing enteropathy by Sara A. Jablonski, Jessica L. Strohmeyer, John P. Buchweitz, Andreas F. Lehner, Daniel K. Langlois

“…Dogs were treated with 1 mg/kg prednisolone PO once daily for approximately 3 weeks. Venous blood samples were collected at set timepoints before and after prednisolone administration on the first (T1) and final (T2) study days. …”
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Effect of high-frequency oscillatory ventilation with intermittent sigh breaths on carbon dioxide levels in neonates by Kulthida Baingam, Anucha Thatrimontrichai, Manapat Praditaukrit, Gunlawadee Maneenil, Supaporn Dissaneevate

“…Results Thirty neonates with a mean gestational age of 33.6±4.1 weeks and median date of intervention of 1.88 days (interquartile range, 0.87–3.79 days) were enrolled. …”
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Breast Implant Illness May Be Rooted in Mast Cell Activation: A Case-Controlled Retrospective Analysis by Èva S. Nagy, BMedSci(Hons), MBBS, PhD, FRACS, Grad Cert (Breast Surgery), Mark Westaway, MBBS, DCH, Grad Dip Allergy, Suzanne Danieletto, BSc, MBBS (Hons), FRCPA, MIAC, Lawrence B. Afrin, MD

“…Mean BII symptom score 2 weeks postexplantation was reduced by 77% (P < 0.0001), and 85% by 9 months. …”
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Healthcare Workers’ SARS-CoV-2 Infections in Four Hospital Outbreaks during Delta Variant Prevalence in Sydney, Australia by Danielle Hutchinson, Mohana Kunasekaran, Haley Stone, Xin Chen, Ashley Quigley, Aye Moa, C. Raina MacIntyre

“…No workplace-acquired HCW infections were reported in these hospitals from critical care wards, where respirators were recommended during the same outbreak weeks. Conclusions. Differences in PPE policy across different wards may leave healthcare staff at risk of SARS-CoV-2 infection. …”
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Vascular Protective Effects of Morinda citrifolia Leaf Extract on Postmenopausal Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Microscopic Level by C. L. G. Chong, Faizah Othman, Farida Hussan

“…Atherosclerosis was induced by producing oestrogen deficiency through ovariectomy and feeding with thermoxidized palm oil (TPO) diet for 12 weeks along with the treatment. The results revealed significantly (P<0.05) lower systolic blood pressure (SBP) in the group treated with MCHD compared to the untreated OVX, whereas the diastolic blood pressure (DBP) was significantly higher in the untreated OVX group compared to the Sham group. …”
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Analysis of retinal sublayers in patients with systemic COVID-19 illness with varying degrees of severity by Mohammad Reza Talebnejad, Mohammad Reza Badie, Hossein Shahriari, M. Hossein Nowroozzadeh

“…Spectralis SD-OCT scans of the macula and optic nerve were obtained from all participants 6 weeks after initial diagnosis. The central subfield thickness of the macula (CSFT), peripapillary retinal nerve fiber layer thickness (pRNFL), and retinal sublayers’ volumes in the total 6-mm ETDRS zone were recorded and analyzed using the ANCOVA test, adjusting for age. …”
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Enhancing stone expulsion: The efficacy of combined medical therapy with tamsulosin and dexamethasone in renal colic patients by Reza Kazemi, Mohammad Shahrashoub, Amir Javid, Narjes Saberi, Pouria Ghasemi, Saina Paymannejad

“…In total, 43 patients had expelled the stone by the end of the 2 weeks, resulting in an overall expulsion rate of 42.5%. …”
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Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

“…In vitro, the cytotoxicity of MCP and its modulatory effect on MTX cytotoxic efficacy were assessed.MethodsFour groups of rats were used: control, MTX (40 mg/kg, single intraperitoneal injection on day 9), MTX + MCP (200 mg/kg/day, orally, for 2 weeks), and MCP alone. MCF7, Nalm6, and JEG3 cell lines were used for the in vitro cytotoxicity assay.ResultsMCP counteracted liver and lung toxicity evidenced by ameliorating the markers of liver and lung functions. …”
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The Effect of an Educational Application on The Quality of Life and Treatment Adherence in Mothers of Children with Congenital Heart Disease Undergoing Cardiac Surgery: A Randomize... by Mohammad Rajabi, Jamalodin Begjani, Reza Negarandeh

“…The intervention group received the educational app upon discharge and used it for four weeks, while the control group received standard discharge education, which consisted of face-to-face education. …”
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Targeting Toll-like receptor 4 and microbiota dysregulation: a new frontier in nonalcoholic fatty liver disease management by K.B. Kvit

“…Patients with NAFLD underwent a microbiome-targeted therapy consisting of rifaximin, probiotics, and essential phospholipids over 12 weeks. Biochemical, microbiota, and inflammatory markers were assessed before and after treatment. …”
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Mediterranean diet improves liver health but does not protect against azoxymethane-induced colon tumorigenesis compared to Western diet in A/J mice by Weimin Guo, Nicholas Crossland, Jimmy W. Crott

“…Azoxymethane (AOM) was used to initiate colon tumorigenesis and mice were maintained for 19 weeks after the final dose. Result: Unexpectedly high mortality was observed amongst male mice following the second AOM dose. …”
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Normative Reference Values and Validity for the 30-Second Chair-Stand Test in Healthy Young Adults by Donald H. Lein Jr., Mansour Alotaibi, Marzouq Almutairi, Harshvardhan Singh

“…Investigators used the International Physical Activity Questionnaire Leisure Domain (LD-IPAQ) to divide participants into insufficiently or sufficiently active groups based on the weekly metabolic equivalent of task per the Physical Activity Guidelines for Americans…”
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Post-operative Rehabilitation for Scapular Muscle Reattachment: A Case Report by Wendy Burke, W Ben Kibler, Tim L Uhl

“…This case report describes the rehabilitation program that took one-year to recover for each arm with a period of protected motion for 16-weeks and gradual return to function as a manual physical therapist over a period of one-year…”
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A novel graph neural network based approach for influenza-like illness nowcasting: exploring the interplay of temporal, geographical, and functional spatial features by Jiajia Luo, Xuan Wang, Xiaomao Fan, Yuxin He, Xiangjun Du, Yao-Qing Chen, Yang Zhao

“…The model inputs consist of weekly matrices of influenza-like illness (ILI) rates at city level, along with geographical topology and functional topology. …”
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Effects of Muse Cell on a Mouse Model With Acute Encephalopathy by Tatsuya Kawaguchi, Tetsuji Mori, Kaori Adachi, Jun Fujii, Yoshihiro Maegaki, Fumiko Obata

“…Results Injection of Muse cells significantly improved body weight gain 1 day after treatment and the survival ratio for 3 weeks. Conclusion These effects could be a result of the direct and/or indirect upregulation of IL‐10, an anti‐inflammatory cytokine, in the Muse cell–treated brain. …”
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How to evaluate a multi-country implementation-focused network: Reflections from the Quality of Care Network (QCN) evaluation. by Gloria Seruwagi, Mike English, Nehla Djellouli, Yusra Shawar, Kasonde Mwaba, Abdul Kuddus, Agnes Kyamulabi, Kohenour Akter, Catherine Nakidde, Hilda Namakula, Mary Kinney, Tim Colbourn, QCN Evaluation Group

“…A 'reflections' tool was developed to guide the process, which happened within a period of 2-4 weeks across the different countries. All country research teams held focused 'reflection' meetings to discuss questions in the tool before sharing responses with this paper's lead author. …”
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An Atypical Presentation of Childhood Paraganglioma with Seizures: A Case Report and Review of the Literature by Elizabeth Eberechi Oyenusi, Uzoamaka Felicia Nwigbo, Oluwadamilola Moromoke Oladipo, Blessing Ebele Kene-Udemezue, Kasarachi Pauline Akowundu, Khadijah Omobusola Oleolo-Ayodeji, Oluwaseun Adunni Afoke, Funmilayo Oluwatoyin Babatunde, Felix Makinde Alakaloko, Gabriel Kolawole Asiyanbi, Ezekiel Olayiwola Ogunleye, Abiola Olufunmilayo Oduwole, Foluso Ebun Afolabi Lesi

“…A 14-year-old girl was referred to the paediatric neurology unit for recurrent headaches of one-year duration, vomiting of 2 months duration, and an episode of generalized tonic-clonic seizures, 2 weeks prior to presentation. There was an associated history of impaired vision, palpitations, diaphoresis, and easy fatigability. …”
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Case report of neurobrucellosis: a rare complication and neuroimaging findings of a common disease by Yu Zhang, Yu Zhang, Xiao-Yi Zou, Xiao-Yi Zou, Ling Liu

“…All patients were treated with rifampicin (450 mg once daily) and minocycline (100 mg twice daily) for at least 12 weeks, and their clinical symptoms showed significant improvements.ConclusionThis report reviews four cases of neurobrucellosis. …”
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NS5A replication complex inhibitor daclatasvir in the basis of chronic hepatitis C interferon-free therapy by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

“…Prescription of the drug in combination to pegilated interferon and ribavirin for treatment-naive patients made possible to reduce treatment duration from 48 to 24 weeks and to increase frequency of sustained virologic response (SVR) to 87% in 1b genotypeand to 100% — in 4-th genotype. …”
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