An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish by Samantha Carrothers, Rafael Trevisan, Nishad Jayasundara, Nicole Pelletier, Emma Weeks, Joel N. Meyer, Richard Di Giulio, Caren Weinhouse

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Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…These mice were fed with a high-fat diet for 9 weeks to induce inflammation. The effects of conditional knockdown of hepatic PCSK9 on inflammation and the underlying mechanisms were investigated by molecular biological techniques. …”
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Comparative Characterization of Trends and Patterns of Physical and Chemical Attributes of Optimal and Traditional Processed Cowpea Leaves by Joshua Ombaka Owade, George Ooko Abong’, Michael Wandayi Okoth, Agnes Wakesho Mwang’ombe

“…With factor analysis determining optimal nutritional quality for cowpea leaves at 8 weeks after emergence, sun drying had the highest loss of beta-carotene and ascorbic acid, 66.7–80.1% and 53.7%–58.3%, respectively (p<0.001), whereas mineral leaching, reduction of antinutrients, and colour changes were more pronounced in dehydration techniques incorporating fermentation as pretreatment. …”
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The Influence of Mode-of-Injury on Psychological Readiness for Return-To-Sport Following Anterior Cruciate Ligament Reconstruction: A Matched-Controlled Study by Jenifer Presley, Lane Bailey, Kevin Maloney, Brian Duncan, Mathew Reid, Christopher Juneau, Walter R Lowe

“…Psychological readiness was examined 16-weeks postoperatively using the ACL-Return to Sport after Injury (ACL-RSI) questionnaire with subgroup analyses for the ‘emotional’, ‘confidence’ and ‘injury-risk’ subscales. …”
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A rare case of Ewing's sarcoma in a 4-year-old child treated by tumor endoprosthetics using 3D printing by Vladimir Stavrev, Luben Stokov, Petko Ganev, Georgi Georgiev

“…Results: The postoperative period was uneventful, with sutures removed on the 12th postoperative day. For 3 weeks, a tutor orthosis was placed. Active physiotherapy was started after removal of the orthosis 21 days after surgery. …”
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Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene by Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu

“…Experimental rats were treated orally with 400 and 800 mg/kg bw TCA daily for four weeks. Antioxidant enzyme activities, plasma glucose concentration, protein concentration, oxidative stress, and inflammation biomarkers were assayed using standard methods. …”
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Models of provider care in long-term care: A rapid scoping review. by Candyce Hamel, Chantelle Garritty, Mona Hersi, Claire Butler, Leila Esmaeilisaraji, Danielle Rice, Sharon Straus, Becky Skidmore, Brian Hutton

“…<h4>Methods</h4>We conducted this review over 10-weeks of English language, peer-reviewed studies published from 2010 onward. …”
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Eales&rsquo; Disease in Inuit: A Short Report and Clinical Update by Forshaw TRJ, Moldow B

“…The right eye was treated in outpatients with sectoral laser photocoagulation. At seven weeks’ follow-up, the visual acuity had improved from 6/12 to 6/6 (right eye) and from 6/36 to 6/7.5 (left eye).Conclusion: The prevalence of tuberculosis in Greenland is very high and it is recommended that clinicians remain alert to the possibility of Eales’ disease, as beneficial visual outcomes are associated with prompt diagnosis and treatment. …”
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Phenolic-Rich Baccaurea angulata Modulates Inflammatory Biomarkers of Atherosclerosis by Muhammad Ibrahim, Maryam Abimbola Mikail, Idris Adewale Ahmed, Radiah Abdul Ghani

“…Group CH was fed 1% cholesterol diet only, group C1 was fed 1% cholesterol diet and 0.5 ml/kg/day B. angulata WF juice, group C2 was fed 1% cholesterol diet and 1.0 ml/kg/day B. angulata WF juice, group C3 was fed 1% cholesterol diet and 1.5 ml/kg/day B. angulata WF juice, group N was fed standard pellet only, group N1 was fed standard pellet and 0.5 ml/kg/day B. angulata WF juice, and group N2 was fed standard pellet and 1.0 ml/kg/day B. angulata WF juice for 12 weeks. Results. The administration of the various juices reduced the concentrations of induced serum inflammatory biomarkers. …”
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Analysis of the Renal Protection and Antioxidative Stress Effects of Panax notoginseng Saponins in Diabetic Nephropathy Mice by Wei Mi, Min Yu, Shuying Yin, Yuhan Ji, Tala Shi, Ning Li

“…A DN mouse model was constructed, and then low, medium, and high doses of PNS were used to intervene the model group mice. Eight weeks after intervention, the 24 h urine protein (UPro) and urinary albumin (UAlb) were quantitatively examined, and the related blood biochemical indices were measured. …”
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E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model by Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Nga T. Le, Carlos T. Huerta, Francesca A. Voza, Hongwei Shao, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Omaida C. Velazquez

“…After three postoperative weeks, hindlimb muscle was harvested for immunofluorescence analysis. …”
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The Association between Intertwin Difference in First Trimester Crown-Rump Length, Nuchal Translucency, and Birth Weight Discordance in Twin Pregnancies: A Retrospective Cohort Stu... by Zachary Michael Ferraro, Tinghua Zhang, Felipe Moretti, Karen Fung-Kee-Fung

“…Although intertwin CRL and NT discordance measured via ultrasound between 11-14 weeks gestation are related to birth weight discordance, there is uncertainty as to whether twin birth weight differences are related to adverse pregnancy outcomes in this population.…”
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Serum IL-1β, IL-2, and IL-6 in Insulin-Dependent Diabetic Children by Yasar Dogan, Saadet Akarsu, Bilal Ustundag, Erdal Yilmaz, Metin Kaya Gurgoze

“…Children with IDDM were divided into three subgroups: (1) previously diagnosed patients (long standing IDDM) (n:15), (2) newly diagnosed patients with diabetic ketoacidosis (before treatment) (n:12), and (3) newly diagnosed patients with diabetic ketoacidosis (after treatment for two weeks) (n:12). In all stages of diabetes higher levels of IL-1β and TNF-α and lower levels of IL-2 and IL-6 were detected. …”
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Using Real‐Time Power BI Formative Feedback to Improve Nurse Anesthesia Students' Clinical Competence: An Educational Intervention by Ali Khalafi, Sajjad Choopani, Nooshin Sarvi‐Sarmeydani, Elham Maraghi

“…The intervention entailed providing immediate, web‐based feedback on students' performance through a visual dashboard on Microsoft Power BI, along with weekly assessments using the Common Clinical Assessment Tool (CCAT). …”
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Ascertaining the Effectiveness of Coordination Training Interventions in Enhancing Sports Performance: A Systematic Review and Meta-analysis by Ashwani Saini, Bipin Kumar Dubey, Rakesh Vishwakarma

“…The studies included were confined to different coordination interventions, such as balance, rhythm, agility, neuromuscular training, jump ropeladder exercises, spatial orientation, non-sports specific and proprioceptive training, ranging from 6 weeks to an annual macrocycle with participants (sub-junior and junior levels) from different sports. …”
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Exercise-Induced Adaptations to the Mouse Striatal Adenosine System by Ella E. Bauer, Trevor J. Buhr, Carter H. Reed, Peter J. Clark

“…The results suggest that eight weeks of running wheel access spared age-related increases of A1R and A2AR protein concentrations across the dorsal and ventral striatal structures. …”
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Cumulative Incidence of Revision for a Balanced Knee System at a Mean 8-Year Follow-Up: A Retrospective Review of 500 Consecutive Total Knee Arthroplasties by Michael H. Bourne, Tony L. Miller, E. Marc Mariani

“…Follow-up was performed at 6 weeks, 6 months, 1 year, 5 years, and 10 years. 48 patients (9.6%) were considered lost to follow-up. …”
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Immediate and Intermediate-Term Outcomes of Infants With Transposition of Great Arteries Who Underwent Balloon Atrial Septostomy in Sudan by Sulafa K. M. Ali, Amna Elsheikh, Mohammed Abdulrahman Alhassan

“…Post-BAS oxygen saturation increased to 87 (IQR 85–90%) with a median improvement of 40% (p = 0.048), which was more significant in those less than 2 weeks of age. Minor complications occurred in 14 patients, and two patients (2.6%) died. …”
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Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats by Tsuyoshi Chiba, Tatsuki Itoh, Masaki Tabuchi, Toru Nakazawa, Takao Satou

“…In this study, we aimed to clarify the role of inflammation in stroke onset among stroke-prone spontaneously hypertensive rats (SHRSP). At 4 weeks of age (before stroke onset), the plasma level of IL-1β was significantly higher in SHRSP (153.0±49.7 pg/ml) than in Wistar Kyoto rats (WKY) (7.7±3.4 pg/ml, P<0.001 versus SHRSP) or spontaneously hypertensive rats (SHR) (28.0±9.1 pg/ml, P<0.001 versus SHRSP) (n=6 per strain). …”
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Healthcare worker views on antimicrobial resistance in chronic respiratory disease by Sachin Ananth, Adekunle O. Adeoti, Animesh Ray, Peter G. Middleton, Miquel Ekkelenkamp, Stephanie Thee, Anand Shah, the AMR-Lung Clinical Research Collaboration

“…Results 279 responses were received across 60 countries. 54.5% of respondents encountered AMR in chronic respiratory disease weekly. There were differences in perceived high-priority diseases and species with AMR burden between Europe, Asia and Africa. 76.4% of respondents thought that inappropriate antimicrobial prescribing in chronic respiratory disease was common. …”
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