Metformin Ameliorates Podocyte Damage by Restoring Renal Tissue Podocalyxin Expression in Type 2 Diabetic Rats by Limin Zhai, Junfei Gu, Di Yang, Wei Wang, Shandong Ye

“…Type 2 diabetic Sprague-Dawley (SD) rats in which diabetes was induced by high-fat diet/streptozotocin (HFD-STZ) were treated with different doses of metformin (150, 300, and 500 mg/kg per day, resp.) for 8 weeks. Various biochemical parameters, kidney histopathology, and renal tissue PCX expression levels were examined. …”
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Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions by Sebnem Calkavur, Senem Alkan Ozdemir, Ruya Colak, Ezgi Yangin Ergon, Ferit Kulali, Tulin Gokmen Yildirim

“…STUDY DESIGN: This is a prospective, an observational study which includes preterm infants of 32 weeks of gestation and/or ≤1500 grams who were referred to Izmir Dr. …”
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Orbital Tumors Excision without Bony Marginotomy under Local and General Anesthesia by Robert A. Goldberg, Daniel B. Rootman, Nariman Nassiri, David B. Samimi, Joseph M. Shadpour

“…The median (range) age and follow-up duration were 48.5 (31–87) years old and 24.5 (4–375) weeks, respectively. Visual acuity and ocular motility showed improvement or no significant change in all but one patient at the latest followup. …”
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Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in... by Claudia Stefanutti, Fabio Mazza, Michael Steiner, Gerald F. Watts, Joel De Nève, Daniela Pasqualetti, Juergen Paal

“…A statistically significantly greater treatment-effect correlation was observed in patients undergoing weekly treatments, compared with those undergoing treatment every 15 days. …”
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Toxicological Assessment of Pseudospondias microcarpa (A. Rich.) Engl. Hydroethanolic Leaf Extract in Rats: Haematological, Biochemical, and Histopathological Studies by Donatus Wewura Adongo, Priscilla Kolibea Mante, Kennedy Kwami Edem Kukuia, Charles Kwaku Benneh, Robert Peter Biney, Eric Boakye-Gyasi, Nicholas Akinwale Titiloye, Eric Woode

“…Male Sprague-Dawley rats (120–150 g) were treated orally with the extract (30, 100, 300, 1000, and 3000 mg kg−1) or distilled water (10 ml kg−1) for 2 weeks and observed daily for general appearance and signs of toxicity. …”
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PET Study in a Patient with Spinocerebellar Degeneration before and after Long-Term Administration of Thyrotropin Releasing Hormone by H. Tanji, H. Nagasawa, T. Hayashi, H. Onodera, T. Fujiwara, M. Itoh, T. Ido, Y. Itoyama

“…A 56-year-old female, who had suffered from progressive ataxia for 2 years, was treated by intravenous administration of 2 mg TRH for 3 weeks, and CMRG1c of the brain was measured before and after treatment. …”
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Metastatic Extrapulmonary Small Cell Carcinoma to the Cerebellopontine Angle: A Case Report and Review of the Literature by Debebe Theodros, C. Rory Goodwin, Genevieve M. Crane, Jason Liauw, Lawrence Kleinberg, Michael Lim

“…Preoperative MRI eight weeks later demonstrated marked enlargement to 35 mm. …”
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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re... by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

“…She received five courses of 100 mg every 4 weeks with monitoring by magnetic resonance imaging (MRI) and viral load in the cerebrospinal fluid, showing clinical improvement, resolution of neurological symptoms, and reduced viral load. …”
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Methotrexate for the Treatment of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation by Amr Nassar, Ghada Elgohary, Tusneem Elhassan, Zubeir Nurgat, Said Y. Mohamed, Mahmoud Aljurf

“…Despite several limitations in data collection and analysis, weekly administration of methotrexate at a median dose of 7.5 mg/m2 seems to be safe with minimal toxicities in the context of both aGVHD and cGVHD treatments. …”
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Biochemical and antioxidant responses of common carp (Cyprinus carpio) exposed to sublethal concentrations of the antiepileptic and analgesic drug gabapentin by J Blahova, P Mikula, P Marsalek, Z Svobodova

“…The present study aimed to evaluate the biochemical and antioxidant responses of common carp after exposure to the antiepileptic and analgesic drug gabapentin at concentrations of 0.1, 1, 10, and 100 μg/l for 4 weeks. The exposure to the highest two concentrations resulted in significant changes in plasma indices such as glucose (only group 100 μg/l), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), lipase, creatine kinase (CK), amylase as well as butyrylcholinesterase (BChE). …”
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Er-Xian Decoction Stimulates Osteoblastic Differentiation of Bone Mesenchymal Stem Cells in Ovariectomized Mice and Its Gene Profile Analysis by Shufen Liu, Jianhua Huang, Jing Wang, Yongjian Zhao, Sheng Lu, Yongjun Wang, Qin Bian

“…In addition, the expression of 26991 genes of bMSCs ex vivo at 2 weeks after EXD-treatment or of bMSCs in vitro after exposure to conditioned serum from EXD-treated rats was measured and analyzed using NimbleGen Gene Expression Profiling and Cluster and pathway analysis. …”
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Surgical Reimplantation for the Correction of Vesicoureteral Reflux following Failed Endoscopic Injection by Boris Chertin, Ksenia Prosolovich, Sagiv Aharon, Ofer Nativ, Sarel Halachmi

“…All patients were followed with an ultrasound 6 weeks following surgery and every 6 months thereafter for an average of 22 months. …”
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Quality Preservation and Shelf-Life Extension of Prickly Pear (<i>Opuntia ficus-indica</i> L. <i>Mill</i>) Using Edible Coatings by Carolina Rodrigues, Cariny Polesca, Isabela Bicalho, Victor Gomes Lauriano Souza, Isabel Coelhoso, Ana Luísa Fernando

“…In this work, the effects of alginate, starch, chitosan, and pectin as coatings on the physicochemical, bioactive, microbiological, and textural properties of two prickly pear varieties (orange and red), kept under refrigeration (5 ± 2 °C) were evaluated for 6 weeks. Coatings proved to be helpful in the maintenance of the fruits’ color and textural properties, especially when pectin was applied. …”
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Liver Dysfunction Associated with Intravenous Methylprednisolone Pulse Therapy in Patients with Graves’ Orbitopathy by Hiroyuki Eguchi, Junichi Tani, Saori Hirao, Munehisa Tsuruta, Ichiro Tokubuchi, Kentaro Yamada, Masataka Kasaoka, Yasuo Teshima, Tatsuyuki Kakuma, Yuji Hiromatsu

“…It suggests that, in patients with GO, evaluation of preexisting risk factors—including viral hepatitis—and careful weekly monitoring of liver function during IVMP therapy and monthly thereafter for 12 months are warranted.…”
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Lifestyle Intervention Involving Calorie Restriction with or without Aerobic Exercise Training Improves Liver Fat in Adults with Visceral Adiposity by Eiichi Yoshimura, Hideaki Kumahara, Takuro Tobina, Takuro Matsuda, Makoto Ayabe, Akira Kiyonaga, Keizo Anzai, Yasuki Higaki, Hiroaki Tanaka

“…The CR + Ex group had a targeted exercise time of 300 min/wk or more at lactate threshold intensity for 12 weeks. Results. Reductions in body weight (CR, -5.3 ± 0.8 kg; CR + Ex, -5.1 ± 0.7 kg), fat mass (CR, -4.9± 0.9 kg; CR + Ex, -4.4 ± 0.6 kg), and visceral fat (CR, -24 ± 5 cm2; CR + Ex, -37 ± 5 cm2) were not statistically different between groups. …”
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Simvastatin Does Not Affect Vitamin D Status, but Low Vitamin D Levels Are Associated with Dyslipidemia: Results from a Randomised, Controlled Trial by Lars Rejnmark, Peter Vestergaard, Lene Heickendorff, Leif Mosekilde

“…We randomised 82 healthy postmenopausal women to one year of treatment with either simvastatin 40 mg/d or placebo and performed measurement at baseline and after 26 and 52 weeks of treatment. The study was completed by 77 subjects. …”
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Determining the Efficacy of Providing Ice Compression for Fitness Enhancement After Speed Endurance Exercise on Reducing Heart Rate, IL-6, and Fatigue Index in Football Athletes by Muhammad Kharis Fajar, Agus Hariyanto, Endang Sri Wahjuni, Dwi Cahyo Kartiko, Gigih Siantoro, Yanyong Phanpheng, I Dewa Made Aryananda Wijaya Kusuma, Bayu Agung Pramono, Afif Rusdiawan, Adi Pranoto

“…A total of 34 male students from the Football Coaching Department at the State University of Surabaya (Indonesia), aged 18-20 years, with a normal BMI, at least 10 years of football training experience, and no injuries in the past 6 months, were selected as research subjects and were given ICEFIT treatment for 4 weeks. Data collection was conducted by measuring heart rate, IL-6 levels, and fatigue index at both the pre- and post-intervention stages. …”
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Exercise as a mean to reverse the detrimental effect of high-fat diet on bone’s fracture characteristics by Ilias Doulamis, Despina N. Perrea, Panagiotis E. Chatzistergos, Athanasios S. Mitousoudis, Stavros K. Kourkoulis

“…Body mass and relevant biochemical parameters were measured for the duration of the experimental protocol (37 weeks). Mechanical strength of both femurs of each animal was assessed in-vitro based on three point bending tests. …”
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Continuous Exercise but Not High Intensity Interval Training Improves Fat Distribution in Overweight Adults by Shelley E. Keating, Elizabeth A. Machan, Helen T. O'Connor, James A. Gerofi, Amanda Sainsbury, Ian D. Caterson, Nathan A. Johnson

“…Work capacity and body composition (dual-energy X-ray absorptiometry) were measured before and after 12 weeks of intervention in 38 previously inactive overweight adults. …”
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Thyroidectomy for Painful Thyroiditis Resistant to Steroid Treatment: Three New Cases with Review of the Literature by Enrico Mazza, Francesco Quaglino, Adolfo Suriani, Nicola Palestini, Cristina Gottero, Renzo Leli, Stefano Taraglio

“…In more severe forms prednisone doses up to 40 mg daily for 2-3 weeks are recommended. Recurrences occur rarely and restoration of steroid treatment cures the disease. …”
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