Neuronal BDNF Signaling Is Necessary for the Effects of Treadmill Exercise on Synaptic Stripping of Axotomized Motoneurons by Joey Krakowiak, Caiyue Liu, Chandana Papudesu, P. Jillian Ward, Jennifer C. Wilhelm, Arthur W. English

“…No further reduction in coverage was found if nerves were cut in knockout mice. Two weeks of moderate daily treadmill exercise following nerve injury in these BDNF knockout mice did not affect synaptic inputs onto motoneurons. …”
Get full text

Vascularization of Nanohydroxyapatite/Collagen/Poly(L-lactic acid) Composites by Implanting Intramuscularly In Vivo by Hai Wang, Xiao Chang, Guixing Qiu, Fuzhai Cui, Xisheng Weng, Baozhong Zhang, Xiaojie Lian, Zhihong Wu

“…Composites were implanted intramuscularly in the groins of rabbits for 2, 6, or 10 weeks (n=5×3). After removing, the macroscopic results showed that there were lots of rich blood supply tissues embracing the composites, and the volumes of tissue were increasing as time goes on. …”
Get full text

Anti-hyperglycemic effects of dihydromyricetin in streptozotocin-induced diabetic rats by Maojun Yao, Hui Teng, Qiyan Lv, Huifang Gao, Tengming Guo, Yiwen Lin, Sihai Gao, Meihu Ma, Lei Chen

“…Fasting blood glucose and body weight were measured at weekly interval. Oral glucose tolerance tests were performed on days 42. …”
Get full text

Assessing the Outcomes of Digital Soil Science Curricula for Agricultural Undergraduates in the Global South by Rico Heidy, de la Puente Mario, de Oro Carlos, Navarro Daniela, Lambis Juan, Londoño Guillermo

“…Employing a meticulous investigative blueprint across three Colombian university campuses situated in pastoral communities, the assessment involved 89 volunteers separated into experimental and control groups over 14 weeks analyzing soil nutrient administration. Scholastic aptitude, student absorption, and viewpoint appraisals were conducted before and after the module. …”
Get full text

Safety and efficacy of oral cancer vaccine B440 in patients with PD-1/PD-L1 inhibitor-resistant advanced urothelial cancer: a study protocol for a phase 1 multicenter, open-label,... by Junya Furukawa, Yasumasa Kakei, Sae Murakami, Hiroshi Kita, Hideto Ueki, Takuto Hara, Jun Teishima, Nobuyuki Hinata, Hideaki Miyake, Masato Fujisawa, Toshiro Shirakawa

“…The patients will be treated orally with B440 once daily for 5 days followed by 2 days for four consecutive courses (4 weeks, 20 treatments). The low-dose group will receive 800 mg (4 capsules) per dose and the high-dose group will receive 1,600 mg (8 capsules) per dose. …”
Get full text

Line-Field Confocal Optical Coherence Tomography of Plaque Psoriasis Under IL-17 Inhibitor Therapy: Artificial Intelligence-Supported Analysis by Hanna B. Wirsching, Oliver J. Mayer, Sophia Schlingmann, Janis R. Thamm, Stefan Schiele, Anna Rubeck, Wera Heinz, Julia Welzel, Sandra Schuh

“…LC-OCT and clinical assessment with a local psoriasis and severity index of the study plaque and a control area were performed before the initiation of therapy as well as after 4 and 12 weeks of treatment. A manual and AI-supported measurement of the thickness of epidermis, stratum corneum, and undulation of the dermo-epidermal junction was carried out. …”
Get full text

Intraoperative Local Administration of Platelet-Rich Plasma (PRP) during Neurolysis Surgery for the Treatment of Digital Nerve Crush Injury by Akira Ikumi, Yuki Hara, Eriko Okano, Sho Kohyama, Norihito Arai, Yu Taniguchi, Hisashi Sugaya, Tomokazu Yoshioka, Akihiro Kanamori, Masashi Yamazaki

“…In the current case report, intraoperative local administration of PRP was performed during neurolysis surgery for a healthy 28-year-old woman with digital nerve crush injury. Five weeks postinjury, surgery was performed due to severe uncontrollable neuropathic pain and no sensory nerve action potential derivation of the index finger. …”
Get full text

Transition from hypothyroidism to Graves’ disease, development of thyroid eye disease, progression to optic neuropathy after inpatient pulse therapy, and long-term administration o... by Koichiro Mizuochi, Yuji Hiromatsu, Yui Nakamura, Aya Sonezaki, Ayaka Adachi, Tamotsu Kato, Nobuhiko Wada, Tomohiro Kurose, Shiho Watanabe

“…Each time, the patient received weekly pulse therapy with no adverse reactions until her ophthalmopathy was relieved. …”
Get full text

Acute graft-versus-host disease: a case report by JIANG Yuyang, TANG Lulu, CHEN Haiju, LV Chunying, XIONG Hongdi, WU Yi

“…A 54-year-old male presented with a fever for two weeks and generalized pruritic erythemas for three days. …”
Get full text

Giant Intrahepatic Subcapsular Haematoma: A Rare Complication following Laparoscopic Cholecystectomy—A Case Report and Literature Review by Eltaib Saad, Lauren O’Connell, Anne M. Browne, W. Khan, R. Waldron, K. Barry, Iqbal Z. Khan

“…A follow-up ultrasound scan after eight weeks confirmed complete resolution of the haematoma. …”
Get full text

Concurrent Intracranial and Spinal Subdural Hematoma in a Teenage Athlete: A Case Report of This Rare Entity by Daniel S. Treister, Sara E. Kingston, Gabriel Zada, Manu Singh, Jesse G. A. Jones, Jena N. Mills, Alexander Lerner, Orest B. Boyko, Meng Law, Anandh Rajamohan, Mark S. Shiroishi

“…Over the next several weeks, there was gradual symptom improvement and the patient returned to his baseline clinical status. …”
Get full text

The influence of range of motion on the functional and structural capacity of the triceps brachii—an experimental study with electromyography by Luís M. Ferreira, Luís Ferreira, Joana Ribeiro, Luís Branquinho, Rafael Peixoto, Luciano Bernardes Leite, Pedro Forte

“…The following variables were collected pre- and post-intervention: triceps brachii circumference, one repetition maximum, and electromyography during dynamic exercise. Over eight weeks, subjects performed this exercise, performing 3 sets of 12 repetitions for each arm, with days of rest in between. …”
Get full text

Clinical and Capillaroscopic Modifications of the Psoriatic Plaque during Therapy: Observations with Oral Acitretin by Giuseppe Stinco, Cinzia Buligan, Enzo Errichetti, Francesca Valent, Pasquale Patrone

“…In the present work we evaluated the effects of acitretin (0.8 mg/kg/day) on videocapillaroscopic alterations and the clinical response in 11 patients affected by plaque psoriasis at the baseline (T0) and after 4 (T1), 8 (T2), and 12 (T3) weeks. A clinical improvement during the treatment with a complete clinical healing of the plaque in 7 of the 11 patients was observed. …”
Get full text

Understanding Delayed T-Cell Priming, Lung Recruitment, and Airway Luminal T-Cell Responses in Host Defense against Pulmonary Tuberculosis by Christopher R. Shaler, Carly Horvath, Rocky Lai, Zhou Xing

“…Central to M.tb effective immune avoidance is its ability to modulate the early innate inflammatory response and prevent the establishment of adaptive T-cell immunity for nearly three weeks. When compared with other intracellular bacterial lung pathogens, such as Legionella pneumophila, or even closely related mycobacterial species such as M. smegmatis, this delay is astonishing. …”
Get full text

Anatomy of electric vehicle fast charging: Peak shaving through a battery energy storage—A case study from Oslo by Antti Rautiainen, Kalle Rauma, Lena Rohde, Antti Supponen, Fabian Raulf, Christian Rehtanz, Pertti Järventausta

“…The analysis shows variations and trends in the daily and weekly charging behaviour depending on the degree of utilization of the charging station. …”
Get full text

Endoscopic Dilation of Refractory Postlaryngectomy Strictures: A Case Series and Literature Review by Patrick L. Stoner, Amy L. Fullerton, Alyssa M. Freeman, Neil N. Chheda, David S. Estores

“…The average interval in between dilations was six weeks. Technical success was achieved in 6/7 patients, and clinical success was achieved in 2/7 patients. 6/7 patients had advancements in Diet/GT scores. …”
Get full text

Dietary Cocoa Powder Improves Hyperlipidemia and Reduces Atherosclerosis in apoE Deficient Mice through the Inhibition of Hepatic Endoplasmic Reticulum Stress by Hua Guan, Yan Lin, Liang Bai, Yingfeng An, Jianan Shang, Zhao Wang, Sihai Zhao, Jianglin Fan, Enqi Liu

“…We fed apoE knockout mice a Western diet supplemented with either 0.2% (low group) or 2% (high group) cocoa powder for 12 weeks. The groups fed dietary cocoa powder showed a significant reduction in both plasma cholesterol levels and aortic atherosclerosis compared to the control group. …”
Get full text

A Double-Blind, Randomized Clinical Trial of Niacinamide 4% versus Hydroquinone 4% in the Treatment of Melasma by Josefina Navarrete-Solís, Juan Pablo Castanedo-Cázares, Bertha Torres-µlvarez, Cuauhtemoc Oros-Ovalle, Cornelia Fuentes-Ahumada, Francisco Javier González, Juan David Martínez-Ramírez, Benjamin Moncada

“…Twenty-seven melasma patients were randomized to receive for eight weeks 4% niacinamide cream on one side of the face, and 4% HQ cream on the other. …”
Get full text

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice by Yang Long, Dan Jia, Libin Wei, Yumei Yang, Haoming Tian, Tao Chen

“…The serum GGT activity was significantly increased after 7 days of pLIVE-GGT1 vector delivery and lasted for about 3 weeks. GGT overexpression reduced the levels of GSSG and GSH in the liver and serum and had no effects on total antioxidative capacity in the liver, kidney, and skeletal muscle except for the pancreas. …”
Get full text

Nasal Adenocarcinoma in a Horse with Metastasis to Lung, Liver, and Bone and Review of Metastasis in Nine Horses with Sinonasal Tumors by Ashley Hanna, Susanne M. Stieger-Vanegas, Jerry R. Heidel, Melissa Esser, John Schlipf, Jacob Mecham

“…This case was an eleven-year-old quarter horse which was evaluated due to a history of a right forelimb lameness of three weeks duration. Two and a half months later he presented again, this time for unilateral epistaxis and persistent right forelimb lameness. …”
Get full text