Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury by Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. MacLean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel

“…Results SCI caused locomotor dysfunction (measured with the Porcine Thoracic Injury Behavior Score) with some recovery over 6 weeks and limited tissue sparing at 6 weeks with no difference between sexes. …”
Get full text

Etanercept Suppresses Arteritis in a Murine Model of Kawasaki Disease: A Comparative Study Involving Different Biological Agents by Ryuji Ohashi, Ryuji Fukazawa, Makoto Watanabe, Hanako Tajima, Noriko Nagi-Miura, Naohito Ohno, Shinichi Tsuchiya, Yuh Fukuda, Shunichi Ogawa, Yasuhiko Itoh

“…CAWS injection induced active inflammation in the aortic root and coronary arteries. At 2 weeks, the vasculitis was reduced only by etanercept, and this effect persisted for the subsequent 2 weeks. …”
Get full text

Efficacy of Abatacept for Arthritis in Patients with an Overlap Syndrome between Rheumatoid Arthritis and Systemic Lupus Erythematosus by Kei Ikeda, Yoshie Sanayama, Sohei Makita, Junichi Hosokawa, Mieko Yamagata, Daiki Nakagomi, Katsuhiko Takabayashi, Hiroshi Nakajima

“…Clinical Disease Activity Index (CDAI) significantly decreased between baseline and 12 weeks () and remained low through 24 weeks. All patients achieved either a good or moderate response according to the EULAR response criteria at 24 weeks. …”
Get full text

Zinc Acetate Hydrate Supplementation versus Polaprezinc Supplementation for Improving Hypozincemia in Hemodialysis Patients: A Randomized Clinical Trial by Etsuko Kumagai, Kazuhiro Furumachi, Akihiro Kurihara, Ken Hosokawa, Keiko Hosohata, Shinji Takai

“…Serum zinc levels of both groups were compared every 4 weeks for 1 year. In both groups, serum zinc levels significantly increased at 4–52 weeks. …”
Get full text

Dietary Supplemental Glutamine Enhances the Percentage of Circulating Endothelial Progenitor Cells in Mice with High-Fat Diet-Induced Obesity Subjected to Hind Limb Ischemia by Chi-Hsuan Ko, Sung-Ling Yeh, Chiu-Li Yeh

“…Mice in the HC and HI groups were fed a high-fat diet which 60% energy provided by fat for 8 weeks. Mice in the HG group were fed the same diet for 4 weeks and then transferred to a high-fat diet with 25% of total protein nitrogen provided as GLN to replace part of the casein for the subsequent 4 weeks. …”
Get full text

Severe Lipoatrophy in a Growth Hormone Deficient Toddler Girl Treated with a Non-Pegylated Long-Acting Growth Hormone by Atilla Büyükgebiz, And Demir

“…Long-acting rhGH (LAGH) preparation offers the advantage of weekly injections, enhancing patient comfort and adherence to treatment. …”
Get full text

Effect of HTST Thermal Treatments on End-Use Quality Characteristics of Goat Milk by B. D. Rohitha Prasantha, K. M. S. Wimalasiri

“…IAP, mesophilic counts were in the range of 980–110 cfu ml−1 (72°C/15–81°C/25 s) and increased from 2236 to 680 cfu ml−1 samples stored at 4 weeks. Results showed that best quality stability of pasteurized goat milk achieved by heat treatments between 72°C/25 s and 75°C/25 s heat treatments up to 3 weeks of storage under 4°C.…”
Get full text

Mathematical Modeling of Public Opinions: Parameter Estimation, Sensitivity Analysis, and Model Uncertainty Using an Agree-Disagree Opinion Model by Sara Bidah, Omar Zakary, Mostafa Rachik, Hanane Ferjouchia

“…In the first poll, we consider only 31 weeks to estimate the parameters of the model, and then, we compare the rest of the data with the outcome of the model over the remaining 21 weeks. …”
Get full text

Akram’s lifestyle: An effective remedy for the management of gastroesophageal reflux disease by Sadia A. Khan, Javeria Z. Khan, Tayyab S. Akhter, Hamama-Tul-Bushra Khaar, Talay Yar, Mohammad A. Randhawa

“…Data obtained before and after two weeks of intervention was analyzed using SPSS version 28.0. …”
Get full text

Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice by Jiayin Zheng, Yue Wang, Song Han, Yanlin Luo, Xiuli Sun, Ning Zhu, Li Zhao, Junfa Li

“…Nevertheless, cPKCβII translocation to the membrane was significantly decreased in the cortex and hippocampus at 8 weeks after STZ injection. The translocation of cPKCγ from the cytosol to the membrane was remarkably decreased in the hippocampus at 2 and 8 weeks and in the cortex and striatum at 8 weeks after STZ injection. …”
Get full text

Increasing Contraception Documentation in an Academic Rheumatology Clinic: A Quality Improvement Approach by Caroline H. Siegel, Deanna Jannat‐Khah, Avi L. Mikhaylov, Patrick Fritz, Erika L. Abramson, Lisa R. Sammaritano, Nancy Pan

“…Objective This quality improvement initiative aimed to increase the rate of provider screening and documentation of contraception use for reproductive‐aged women seen in an academic rheumatology fellows’ clinic to >50% by 24 weeks, with sustained improvement at one year. Methods With a multidisciplinary team, we devised and implemented six interventional cycles over 24 weeks informed by key stakeholder survey responses. …”
Get full text

Subseasonal Prediction of Heat‐Related Mortality in Switzerland by Maria Pyrina, Ana M. Vicedo‐Cabrera, Dominik Büeler, Sidharth Sivaraj, Christoph Spirig, Daniela I. V. Domeisen

“…Heat‐related mortality peaks occurring for a few days can be accurately predicted up to 2 weeks ahead, while longer periods of heat‐related mortality lasting a few weeks can be anticipated 3 to even 4 weeks ahead. …”
Get full text

TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

“…RDEs were 1600 mg every 2 weeks or 2400 mg every 3 weeks for M6223 monotherapy and 1600+1200 mg every 2 weeks for M6223+BA.Conclusions M6223±BA had a manageable safety profile, with RDEs defined for both monotherapy and combination therapy. …”
Get full text

Trimethoprim Use prior to Pregnancy and the Risk of Congenital Malformation: A Register-Based Nationwide Cohort Study by Jon Trærup Andersen, Morten Petersen, Espen Jimenez-Solem, Jeppe Nørgaard Rasmussen, Nadia Lyhne Andersen, Shoaib Afzal, Kasper Broedbaek, Brian Rafn Hjelvang, Lars Køber, Christian Torp-Pedersen, Henrik Enghusen Poulsen

“…The aim of the study was to investigate whether the use of the antifolate antibiotic trimethoprim during the 12 weeks before conception was associated with congenital malformations. …”
Get full text

A Case of Pregnancy Complicated by the Development of a Tubo-Ovarian Abscess Following an Aspiration of Endometrioma During Oocyte Pick up by Recep Emre Okyay, Ali Cenk Özay, Özlen Emekçi, Ali Rıza Taylan Bodur, Ömer Erbil Doğan

“… A 28 year old nulligravid woman applied to our department at 26 weeks’ gestation with a severe abdominal pain. She had a medical history of an endometrioma aspiration during IVF cycle. …”
Get full text

Fluorescein Angiographic Findings of Peripheral Retinal Vasculature after Intravitreal Conbercept versus Ranibizumab for Retinopathy of Prematurity by Enzhong Jin, Hong Yin, Yufei Gui, Juan Chen, Jian Zhang, Jianhong Liang, Xiao-xin Li, Mingwei Zhao

“…For the IVR group, they were 28.83 ± 2.34 weeks, 1255.0 ± 356.9 g, and 39.42 ± 2.77 weeks, respectively (P=0.817, 0.522, and 0.075). …”
Get full text

Experience in the Management of Patients with Chronic Vascular Ulcers of the Lower Limbs Using Negatively Charged Polystyrene Microspheres by María Teresa Cacua Sánchez

“…The median time of lesion onset was 28 weeks, with a maximum of 2080 and a minimum of 8 weeks. …”
Get full text

Levilactobacillus brevis CD2 as a multifaceted probiotic to preserve oral health: results of a double-blind, randomized, placebo-controlled trial in healthy adults by Serena Altamura, Francesca Lombardi, Francesca Rosaria Augello, Antonella Barone, Mario Giannoni, Benedetta Cinque, Davide Pietropaoli

“…Clinical and salivary parameters were assessed at baseline, after four weeks of intervention, and two weeks post-intervention. …”
Get full text

Reproductive and genotoxic effects of dinotefuran in male Sprague Dawley rats by A. G. Abdelkader, W. H. Mohamed, M. Abou-Ellail, K. A. Amein

“…To achieve these objectives, forty male 10–12 weeks old Sprague Dawley rats were randomly divided into four equal groups; the first group was used as a control group; the other three groups were exposed to 40, 61, and 122 mg/kg body weight DIN by oral gavage for 8 weeks. …”

A Randomized Case-Series Study Comparing the Stability of Implant with Two Different Surfaces Placed in Fresh Extraction Sockets and Immediately Loaded by Leonardo Vanden Bogaerde, Lars Sennerby

“…The test implants were significantly more stable than the control ones after 12 weeks. Conclusions. The results from the present study indicated that the hydrophilic and rougher test implant was more resistant to immediate loading and showed a significantly higher stability than the smoother control implant after 12 weeks.…”
Get full text