Long-term safety and sustained efficacy of bimekizumab in patients with ankylosing spondylitis (radiographic axial spondyloarthritis): 5-year results from BE AGILE (phase 2b) and i... by Sofia Ramiro, Désirée van der Heijde, Atul Deodhar, Xenofon Baraliakos, Denis Poddubnyy, Lianne S Gensler, Helena Marzo-Ortega, Natasha de Peyrecave, Victoria Navarro-Compán, Tetsuya Tomita, Carmen Fleurinck, Ute Massow, Thomas Vaux

“…Objective Assess long-term safety, tolerability and efficacy of bimekizumab in ankylosing spondylitis (radiographic axial spondyloarthritis (r-axSpA)).Methods Patients with active r-axSpA completing the dose-ranging 48-week randomised controlled trial could enrol in the open-label extension, where patients received bimekizumab 160 mg every 4 weeks. …”
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Repetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study by Foglia SD, Drapeau CC, Ramdeo KR, Adams FC, Soppitt DB, Rehsi RS, Shanthanna H, Nelson AJ

“…The objective of this study was to investigate the feasibility of using rTMS in CRPS patients, to improve pain intensity and quality of life.Patients and Methods: Six participants (5 lower limb, 1 upper limb, 42 ± 9 yr) took part in an open-label rTMS study comprised of a 9-week intervention and 6-month follow-up. Participants took part in a 4-week induction period (5 days per week) followed by a 5-week tapering period whereby the frequency of rTMS sessions per week was reduced. rTMS was delivered at 10 hz for 2000 pulses at 80% of resting motor threshold over the primary motor cortex. …”
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Associations between caregivers’ health behaviours and overweight/obesity among children aged 2–6 years in Beijing, China: a cross-sectional study by Yan Hu, Juan Du, Wenjing Ji, Xueling Li, Aimin Liang, Xiwei Xu

“…Additionally, children whose caregivers consumed sweets 2–3 times/week (OR 1.535, 95% CI 1.133 to 2.081) or ≥4 times/week (OR 1.916, 95% CI 1.258 to 2.918), as well as children whose caregivers consumed fast food ≥4 times/week (OR 2.298, 95% CI 1.349 to 3.914), were more likely to be overweight and obesity than children whose caregivers consumed these foods ≤1 time/week. …”
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Is Telephysiotherapy an Option for Improved Quality of Life in Patients with Osteoarthritis of the Knee? by Adesola C. Odole, Oluwatobi D. Ojo

“…This study investigated effect of a 6-week telephysiotherapy programme on quality of life (QoL) of patients with knee osteoarthritis (OA). …”
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Utilization of Project Kind-Er (Engagement in Reading) to Strengthen the Foundation of Learning in Kindergarten by Ma. Benilda Ricaplanca, Mart Albert De Guzman, Christian Bautista

“…The curriculum initially presents two letters each week and another two in the subsequent weeks, which may challenge five-year-old pupils in comprehending the abstract nature of the alphabet. …”
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Question Wording Matters in Measuring Frequency of Fear of Crime: A Survey Experiment of the Anchoring Effect by Aubrey L. Etopio, Emily R. Berthelot

“…We hypothesized that the year condition would yield lower frequency and higher intensity reports, followed by the month condition, and then the week condition. We did not find differences in intensity between conditions, but we found stark differences in frequencies between the year, month, and week conditions in the hypothesized direction. …”
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Predictive Value of Eosinophilia and Basophilia in the Diagnosis of Bronchopulmonary Dysplasia in Premature Infants by Melek Buyukeren, Hasan Tolga Celik, Sule Yigit, Murat Yurdakok

“…RESULTS: In the study group, there was a statistically significant difference in the severity of eosinophilia and basophilia in the first day, first week, second week, third week, and fourth week compared to the control group (p<0.05). …”
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Death to the Coral Reefs and More Money for Everybody Else

“…It was a bad week for the residents of the world’s rapidly disappearing coral reefs, says Science in its lead story. …”
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Peripartum energy metabolism of prolific ewes and their progeny in response to prepartum feeding and litter size by M. Plante-Dubé, R. Bourassa, P. Luimes, S. Buczinski, F. Castonguay, R. Gervais

“…On average, during week −5 to week −2 of gestation, EHIGH promoted the highest DMI and MEI, resulting in an increase of 0.16 BCS points between the pretreatment week and week −1 prepartum. …”
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Comparing the Institution-based Supervision and Tele-based Supervision for Task-oriented Exercises on Upper Limb Motor Performance and Functional Ability among Stroke Patients: A R... by Neha, Subhasish Chatterjee

“…Both groups will perform task-oriented exercises for 30 minutes, three days a week for eight weeks. There will be a 30-second break before switching tasks. …”
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Monitoring Sleep and Nightly Recovery with Wrist-Worn Wearables: Links to Training Load and Performance Adaptations by Olli-Pekka Nuuttila, Daniela Schäfer Olstad, Kaisu Martinmäki, Arja Uusitalo, Heikki Kyröläinen

“…A total of 24 participants (10 females) performed a 3-week baseline training period (BL), a 2-week overload period (OL), and a 1-week recovery period (REC), which were followed by test days (T1–T3). …”
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Impact of health education on knowledge retention among caregivers of hypertensive patients: A prospective cross-sectional study in rural Malawi. by Chikondi Maluwa, Sitalire Kapira, Hataichanok Chuljerm, Wason Parklak, Kanokwan Kulprachakarn

“…Attitude improved from 16.76 (93.1%) at baseline to 17.74 (98.6%) at the six-week mark. Similarly, the mean practice score rose from 25.24 (78.9%) at baseline to 27.42 (85.7%) at week six. …”
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Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues by Shih-Yi Kao, Jia-Fwu Shyu, Hwai-Shi Wang, Chi-Hung Lin, Cheng-Hsi Su, Tien-Hua Chen, Zen-Chung Weng, Pei-Jiun Tsai

“…BM-IPCs reduced blood glucose levels at first week but gradually increased since week 3. In resected pancreas-IPCs group, blood glucose levels were significantly reduced till two weeks after transplantation and gradually increased since week 4. …”
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Astronomical Units to Merge as UK Cows Face Bloody Purge

“…Nature leads this week with a story about a proposal to fuse space-based astronomy funded by NASA with ground-based astronomy funded by the National Space Foundation (NSF). …”
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I’ll Show You Mine, If You Show Me Yours

“…The human genome dominated science news last week. Both Science and Nature lead this week with articles about the simultaneous publication of the human genome sequence by the private company Celera Genomics and the publicly funded Human Genome Project (HGP).…”
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Glucose Metabolism of Human Prostate Cancer Mouse Xenografts by Hossein Jadvar, Xiankui Li, Antranik Shahinian, Ryan Park, Michel Tohme, Jacek Pinski, Peter S. Conti

“…Glucose metabolism was higher in the PC-3 tumor than in the CWR-22 tumor at both the 3-week (by 18%) and the 5-week (by 9.6%) micro-PET imaging sessions. …”
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Analyzing the Effect of Dancesport on Reducing Menopausal Symptoms and Increasing Quality of Life by Noortje Anita Kumaat, Soni Sulistyarto, Ratna Candra Dewi, Heri Wahyudi, Caturia Sasti Sulistyana, Nugroho Susanto, Ozgur Eken, Septyaningrum Putri Purwoto

“…The program involved a 12-week dance course, meeting twice a week for 60 minutes per session, including cha-cha, salsa, rumba, hip-hop, and waltz dances. …”
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Efektifitas Terapi Senam Stroke Terhadap Perbaikan Kemampuan Fungsional Pasien Paska Stroke by Neri Basmara, Reni Prima Gusty, Ema Julita

“…This study aimed to determine the difference in effectiveness of exercise therapy twice a week and three times a week in improving the functional abilities of stroke patients. …”
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Three Prospective Case Studies Examining Mifepristone’s Efficacy in Patients with Treatment-Resistant PTSD by Agnes van Minnen, Lizelotte Vos, Pierre M. Bet, Ad de Jongh, Felix Linsen, Hein J. F. van Marle, Onno C. Meijer, Willem M. Otte, Marije Russcher, Christiaan H. Vinkers

“…Three patients with PTSD who were resistant to standard psychological and pharmacological treatments were prescribed mifepristone (600–1,200 mg/day) for 1 week. A baseline-controlled single-case design was used, involving a 2-week baseline phase (no intervention), a 1-week intervention phase (mifepristone), and a 2-week postintervention phase. …”
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Walking for transport and all-cause mortality: a prospective cohort study of Australian community-dwelling older adults by Rory Wolfe, Neville Owen, Ben Beck, Yang Chen, David W Dunstan, Alice Owen, Robyn L Woods, Danijela Gasevic, Joanne Ryan, Shivangi Shah, Carlene Britt

“…Cox proportional-hazards models (HR and 95% CI) assessed the association between transport-related walking and all-cause mortality.Results Of participants, 44.1% reported walking every day, 31.5% more than once a week, 21.7% rarely or once a week and 2.7% never engaged in transport-related walking. …”
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