Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

“…Preliminary findings highlight dynamic fluctuations in blood-based biomarkers in the first week of pmTBI, with ongoing evidence of protein release (NFL) at 4 months. …”
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Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…Qualitative data were thematically analysed.Results All participants completed preworkshop and postworkshop questionnaires, and 6 completed the 6-week follow-up (75% retention). Feasibility findings suggest the intervention is acceptable and relevant to journalists, with participants indicating the workshop increased confidence with reporting on medical research. …”
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Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…The EC and PE groups underwent a Masashi swimming protocol (120 min per session, 6 days/week, for 15 days). Results indicated that the concentrations of leptin (LP) in the EC group were significantly lower than those in the NC group (p<0.05). …”
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The Efficacy of Functional and Traditional Exercise on the Body Composition and Determinants of Physical Fitness of Older Women: A Randomized Crossover Trial by Antônio Gomes de Resende-Neto, José Carlos Aragão-Santos, Bruna Caroline Oliveira-Andrade, Alan Bruno Silva Vasconcelos, Clodoaldo Antônio De Sá, Felipe José Aidar, Josimari Melo DeSantana, Eduardo Lusa Cadore, Marzo Edir Da Silva-Grigoletto

“…This is a randomized clinical trial in which participants performed two 12-week periods of different training methods, separated by eight weeks of washout. …”
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A systematic scoping review of latent class analysis applied to accelerometry-assessed physical activity and sedentary behavior. by Michael Kebede, Annie Green Howard, Yumeng Ren, Blake Anuskiewicz, Chongzhi Di, Melissa A Troester, Kelly R Evenson

“…The accelerometer-based variables in the LCA model included measures by day of the week (38%), weekday vs. weekend (13%), weekly average (13%), dichotomized minutes/day (13%), sex specific z-scores (13%), and hour-by-hour (13%). …”
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HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway by Min Zhao, Yao-Yao Bian, Li-Li Yang, Yan-Qi Chen, Ya-Jie Wang, Yan-Ting Ma, Yu-Qiong Pei, Wen-Lin Li, Li Zeng

“…In this study, the model of Intrapetitoneal adhesion was established by cecum abrasion and treated with HXTF for one week. RAW264.7 cells were given LPS, IFN-γ, IL-4, HXTF-medicated serum, and PPAR-γ agonist/antagonist, respectively. …”
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Adherence to Mediterranean-Like Dietary Pattern in Association with Gastroesophageal Reflux Disease in Adolescents by Azam AhmadiVasmehjani, Sara Beigrezaei, Zahra Nafei, Nasrin Behniafard, Zahra Darabi, Amin Salehi-Abargouei, Majid Aflatoonian

“…GERD symp­toms and the frequency of their occurrence over the last week were assessed using a validated GERD questionnaire. …”
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Effect of metformin on the neuronal morphology of frontal cortex and hippocampal regions in lipopolysaccharide induced neuroinflammation in male Wistar rats by Vandana Blossom, Sheetal D. Ullal, Rajalakshmi Rai, Amit Massand, Chettiar Ganesh Kumar, Teresa Joy, Melisha Michael D souza, B.V. Murlimanju

“…Methods: This is an animal model study, which utilized the twenty-four male Wistar rats of about 6 weeks old. The rats were divided into 4 groups, which included control, experimental and treatment groups. 170 μg/kg of LPS injection was administered intraperitoneally once a week for the first eight weeks and the treatment groups received metformin, which was administered orally (100 mg and 200 mg/kg body weight/day). …”
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Long-Term Dietary Nitrate Supplementation Does Not Prevent Development of the Metabolic Syndrome in Mice Fed a High-Fat Diet by V. B. Matthews, R. Hollingshead, H. Koch, K. D. Croft, N. C. Ward

“…To investigate the effect of long-term dietary nitrate supplementation on development of the metabolic syndrome in mice fed a high-fat diet. Methods. Following 1 week of acclimatisation, male (6–8 weeks) C57BL6 mice were randomly assigned to the following groups (10/group) for 12 weeks: (i) normal chow + NaCl (1 mmol/kg/day), (ii) normal chow + NaNO3 (1 mmol/kg/day), (iii) high-fat diet + NaCl (1 mmol/kg/day), and (iv) high-fat diet + NaNO3 (1 mmol/kg/day). …”
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Transient sex-related changes in the mice hypothalamo–pituitary–adrenal (HPA) axis during the acute phase of the inflammatory process by T. Daneva, E. Spinedi, R. Hadid, M.-C. Jacquier, M. Giacomini, R. C. Gaillard

“…The potential role of endogenous sex hormones in regulating hypothalamo–pituitary–adrenal (HPA) axis function was investigated after a single injection of endotoxin in adult (8 week old) BALB/c mice of both sexes. The effect of LPS on plasma ACTH, corticosterone (B), testosterone and oestradiol (E) levels and on anterior pituitary (AP) ACTH and adrenal B contents at different times after treatment was studied. …”
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Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…<h4>Results</h4>Overall, 181 patients were screened and 75 enrolled with 80% 6-week, 82.7% 3-month and 84% 6-month follow-up rates showing appropriate Reach and retention. …”
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“Inclisiran: Early LDL-C target achievement in a real-life population” by Francesco Briani, Mauro Bagli, Gabriele Venturi, Francesco Bacchion, Antonio Mugnolo

“…Blood samples were collected before the inclisiran administration and at week and one month afterward with the aim toevaluate achievement of LDL-C targets at these time intervals (primary endpoint) and reduction in LDL-C levels (secondary endpoint). …”
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The Effect of Blood Flow Restriction Therapy on Shoulder Function Following Shoulder Stabilization Surgery: A Case Series by John H. McGinniss, John S. Mason, Jamie B. Morris, Will Pitt, Erin M. Miller, Michael S. Crowell

“… # Hypothesis/Purpose To observe changes in shoulder strength, self-reported function, upper extremity performance, and range of motion (ROM) in military cadets recovering from shoulder stabilization surgery who completed a standard rehabilitation program with six weeks of BFR training. # Study Design Prospective case series # Methods Military cadets who underwent shoulder stabilization surgery completed six weeks of upper extremity BFR training, beginning post-op week six. …”
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Addressing unmet mental health needs of older adults in Turbo, Colombia: a multi-component psychosocial intervention feasibility study by Clarissa Giebel, Erika Montoya, Gabriel Saldarriaga, Thais Caprioli, Mark Gabbay, Danicza Martinez, Jessica Rua, Maria Isabel Zuluaga

“…The co-produced intervention ran for three months in 2023, with two sessions provided per week in a community centre (26 sessions in total). …”
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Endoscopy-assisted anterior cervical discectomy and fusion with internal fixation vs conventional surgery in the treatment of cervical disc herniation by Haicun Zhang, Yanbo Lin, Canglu Wu, Fangling Cheng, Danqing Bao, Yuyan Chen

“…Following operation, there were significant differences between the 2 groups with respect to RIS at 1 week and 6 months postsurgery and hemoglobin levels on postoperative day 2. …”
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Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery by Pinghui Wei, George PM Cheng, Jiamei Zhang, Alex LK Ng, Tommy CY Chan, Vishal Jhanji, Yan Wang

“…CV was measured with Scheimpflug-based corneal topography at preoperatively and at day 1, week 1, and months 1 and 3 postoperatively. CV measured within 5 mm diameter was defined as central region volume (CV5) and between 5 mm and 10 mm diameter was defined as peripheral region volume (CV5-10). …”
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Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function. by Bo Ning Wang, Xin Zhuo Zhang, Jin Yi Wu, Zhao Yu Zhang, Pei Kun Cong, Wen Wen Zheng, Shao Rong Long, Ruo Dan Liu, Jing Cui, Zhong Quan Wang

“…The levels of Th1/Th2 cytokines (IFN-γ/IL-4) secreted from spleen, mesenteric lymph nodes and Peyer's patches were distinctly increased at 6 weeks following vaccination (P < 0.05). At one week after challenge, the numbers of goblet cells and expression level of Muc2, Muc5ac and pro-inflammatory cytokines (TNF-α and IL-1β) in gut tissues of vaccinated mice were obviously decreased, while expression of anti-inflammatory cytokines (IL-4 and IL-10) was evidently increased, compared to the infected PBS group. …”
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The Response of the Pulp-Dentine Complex, PDL, and Bone to Three Calcium Silicate-Based Cements: A Histological Study in an Animal Rat Model by Ranjdar Mahmood Talabani, Balkees Taha Garib, Reza Masaeli

“…Results. In the first week, BD produced more inflammatory response in the pulpal (score 3) than other materials (score 2). …”
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Effect of an Electronic Pill Bottle on Hydroxychloroquine Adherence in Pediatric Lupus: Results of a Novel Direct‐to‐Family Pilot Trial by Rachel L. Randell, Laura E. Schanberg, Claire Beard, Thomas Phillips, Christoph P. Hornik, Michael Cohen‐Wolkowiez, Stephen J. Balevic, with the CARRA Registry investigators

“…All participants received a pill bottle with a sensor in the cap to record openings and provide automated reminders, which were activated after a two‐week run‐in. The primary outcome was a change in adherence measured using the pill bottle over six months. …”
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A Chlorin e6 derivative-mediated photodynamic therapy versus doxycycline for moderate-to-severe rosacea: A prospective, randomized, controlled study by Yun Wu, Qing Fan, Xiaojing Liu, Yajing Cao, Jin Yang, Yu Yan, Hui Tao, Fuhe Zhang, Linglin Zhang, Peiru Wang, Xiuli Wang

“…Methods: In this prospective, randomised, evaluator-blind controlled study, patients with moderate-to-severe rosacea were assigned to receive up to six STBF-PDT sessions or 100 mg of doxycycline daily for eight weeks, followed by a 24-week follow-up. Results: A total of 76 patients were enrolled (38 assigned to STBF-PDT and 38 to oral doxycycline) with 69 (36 in the STBF-PDT group and 33 in the doxycycline group) completing the study. …”
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