Multicentre, 26-week, open-label phase 2 trial of the JAK inhibitor filgotinib in Behçet’s disease, idiopathic inflammatory myopathies and IgG4-related disease: DRIMID study protocol by Sander W Tas, Joost Raaphorst, Paco M J Welsing, Jacob M van Laar, Rogier M Thurlings, Robbert J Goekoop, César Magro Checa, Jan A M van Laar, Bettina C Geertsema-Hoeve, Nicolle H Rekers, Erik Present

“…The Drug Rediscovery in IMIDs (DRIMID) consortium aims to conduct a prospective pilot basket trial to investigate the effects of filgotinib, a JAK1 preferential inhibitor approved for ulcerative colitis and rheumatoid arthritis, on disease activity, quality of life and safety in patients with refractory BD, IIM and IgG4-RD.Methods and analysis In this investigator-initiated, multicentre, open-label phase 2 study, up to 60 patients with rare IMIDs will be enrolled for a 26-week treatment period with filgotinib 200 mg once daily. …”
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Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial (The QUANTUM Trip Trial) by Claus Thorn Ekstrøm, Patrick MacDonald Fisher, Gitte Moos Knudsen, Dea Siggaard Stenbæk, Anders Fink-Jensen, Mathias Ebbesen Jensen, Tobias Søgaard Juul

“…Outcome assessments will be carried out 1, 4, 8 and 12 weeks postdosing. The primary outcome is reduction in the percentage of heavy drinking days from baseline to follow-up at 12 weeks. …”
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Perinatal mortality and other severe adverse outcomes following planned birth at 39 weeks versus expectant management in low-risk women: a population based cohort studyResearch in context by Kylie Crawford, Waldemar A. Carlo, Anthony Odibo, Aris Papageorghiou, William Tarnow-Mordi, Sailesh Kumar

“…Summary: Background: Planned birth by induction of labour in low-risk, nulliparous women at 39+0–39+6 weeks gestation is associated with fewer caesarean sections, adverse maternal and neonatal outcomes and perinatal deaths compared with expectant management. …”
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Development of Antimicrobial Biopolymer Film Incorporated with a Mixture of Sodium Lactate and Diacetate and Studying its Efficacy Against Listeria monocytogenes and Microbiological Spoilage in Deli Meat Over 12 Weeks of Storage by Katherine Sierra, Luis Guzman, Vianca Tashiguano, Micah T. Black, Payten Leeds, Jakob Doster, Laura J. Garner, Sungeun Cho, Yucheng Peng, Amit Morey

“…Research was conducted to (1) develop and evaluate mechanical properties of plastic-alternative films with chicken skin gelatin and antimicrobials (a mixture of sodium lactate and sodium diacetate (LD)); and (2) evaluate the efficacy of the antimicrobial films against Listeria monocytogenes and microbiological spoilage of fully cooked, beef bologna. Through the 12-week storage, the LD biopolymer film initially exhibited bacteriostatic effects, followed by bactericidal (decrease of ∼2 log CFU/g), and again bacteriostatic effect on the pathogen during weeks 0–4, 5–6, and 7–12, respectively. …”
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Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaçao: Observational Cohort Study by Maaike C Swets, Steven R Kerr, Brian MacKenna, Louis Fisher, Merel van Wijnen, Diederik Brandwagt, Paul W Schenk, Pieter Fraaij, Leonardus G Visser, Sebastian Bacon, Amir Mehrkar, Alistair Nichol, Patrick Twomey, Philippa C Matthews, Malcolm G Semple, Geert H Groeneveld, Ben Goldacre, Iain Jones, J Kenneth Baillie

“…The rate of elevated AST or ALT test for 3-week- to 5-year-olds was compared between a period of interest in which cases of hepatitis were reported (December 1, 2021, to August 31, 2022) and a prepandemic baseline period (January 1, 2012, to December 31, 2019). …”
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CONTEXT MATHEMATICAL PROBLEMS IN THE FORMATION OF CORE COMPETENCES OF ENGINEERING STUDENTS by Olga V. Yanuschik, Victor А. Dalinger

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Feasibility and therapeutic efficacy of a two-week low-level laser acupuncture therapy for shoulder and neck pain in office workers: Protocol for a pilot, single-blind, double-armed, randomised controlled trial. by Carol Chunfeng Wang, Lisa Whitehead, Travis Cruickshank, Johnny Lo, Jianhong Cecilia Xia, Jun Wen

“…Each of the two study groups will contain 35 participants: the intervention group will receive LLLA from a licensed acupuncturist at the researchers' university clinic (10-20 min/session, 3 sessions/week) for two weeks; the control group will receive usual care without painkillers. …”
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Zinc Chloride Smoke Inhalation Induced Severe Acute Respiratory Distress Syndrome: First Survival in the United States with Extended Duration (Five Weeks) Therapy with High Dose Corticosteroids in Combination with Lung Protective Ventilation by Hafiz Mahboob, Robert Richeson III, Robert McCain

“…We report the first survival of smoke induced severe ARDS in the United States (US) with prolonged use of high dose steroids (five weeks) and lung protective ventilation alone. Previously reported surviving patients in China and Taiwan required extracorporeal membrane oxygenation (ECMO) and other invasive modalities. …”
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Re‐evaluation of citric acid esters of mono‐ and diglycerides of fatty acids (E 472c) as a food additive in foods for infants below 16 weeks of age and follow‐up of its re‐evaluation by EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Sabina Passamonti, Detlef Wölfle, Birgit Dusemund, Dominique Turck, Stefania Barmaz, Alexandra Tard, Ana Maria Rincon

“…Regarding the safety of the use of E 472c in food for infants below 16 weeks of age, the Panel concluded that there is no safety concern from its use at the reported use levels and at the maximum permitted levels in food for infants below 16 weeks of age (FCs 13.1.1 and 13.1.5.1).…”
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Prevalence and risk factors of postpartum depression, general depressive symptoms, anxiety and stress (PODSAS) among mothers during their 4-week postnatal follow-up in five public health clinics in Perak: A study protocol for a cross-sectional study by Boon How Chew, Subashini Ambigapathy, Saidatul Akmar Mohammad Redzuan, Priyasini Suntharalingam, Thenmoli Palaniyappan, Venotha Ganasan, Puteri Normalina Megat Abu Bakar, Paream Kaur, Lili Zuryani Marmuji, V Paranthaman

“…Participants will be mothers aged 18 years and above at 4 weeks postdelivery who are able to understand the English and Malay languages. …”
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Fifty-Two-Week Results of Clinical and Imaging Assessments of a Patient with Rheumatoid Arthritis Complicated by Systemic Sclerosis with Interstitial Pneumonia and Type 1 Diabetes despite Multiple Disease-Modifying Antirheumatic Drug Therapy That Was Successfully Treated with Baricitinib: A Novel Case Report by Yuya Fujita, Masao Nawata, Atsushi Nagayasu, Kazuki Someya, Kazuyoshi Saito, Yoshiya Tanaka

“…We report that baricitinib was effective for systemic sclerosis and type 1 diabetes, as well as for rheumatoid arthritis, for up to 52 weeks.…”
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Beeswax Alcohol (BWA, Raydel^®) Improved Blood Oxidative Variables and Ameliorated Severe Damage of Zebrafish Kidneys, Testes, and Ovaries Impaired by 24-Week Consumption of a High-Cholesterol and High-Galactose Diet: A Comparative Analysis with Coenzyme Q₁₀ by Kyung-Hyun Cho, Ashutosh Bahuguna, Ji-Eun Kim, Yunki Lee, Sang Hyuk Lee, Cheolmin Jeon, Cheol-Hee Kim

“…Methods: Adult zebrafish were fed various HC+Gal diets enriched with either BWA or CoQ₁₀. After 24 weeks of dietary intervention, blood and organs were harvested for subsequent biochemical and histological evaluations. …”
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Türk Kütüphanecilik Tarihi ve Önemli Kütüphanelerimiz by Hakan Anameriç

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Impact of atrial fibrillation on productivity in working-age patients: an analysis of Swiss-AF prospective cohort study data by Helena Aebersold, Fabienne Foster-Witassek, Sina Amberg, Miquel Serra-Burriel, Giorgio Moschovitis, Raffaele Zannoni, Stefanie Aeschbacher, Giulio Conte, Jürg H. Beer, Eva Blozik, Leo H. Bonati, David Conen, Stefan Felder, Moa L. Haller, Philipp Krisai, Michael Kühne, Rebecca E. Paladini, Tobias Reichlin, Nicolas Rodondi, Christian Sticherling, Thomas Szucs, Yuki Tomonaga, Stefan Osswald, Matthias Schwenkglenks

“…Swiss Medical Weekly…”
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Prevalence and incidence of sarcopenia in Swiss postmenopausal women: findings from the OsteoLaus Cohort by Colin Vendrami, Elena Gonzalez Rodriguez, Guillaume Gatineau, Peter Vollenweider, Pedro Marques-Vidal, Olivier Lamy, Didier Hans, Enisa Shevroja

“…Swiss Medical Weekly…”
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Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature by Ramona Meier-Lienhard, Cosima Suter, Thomas Pabst, Felicitas Hitz, Jakob R. Passweg, Olivier Spertini, Nathan Cantoni, Daniel Betticher, Lucas Simeon, Michael Medinger, Stefanie Hayoz, Adrian Schmidt

“…Swiss Medical Weekly…”
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Reimbursement policies of Swiss health insurances for the surgical treatment of symptomatic breast hypertrophy: a retrospective cohort study by Astrid Navarra, Daniel Schmauss, Reto Wettstein, Yves Harder

“…Swiss Medical Weekly…”
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Channa striata (Ikan Gabus) Extract and the Acceleration of Tuberculosis Treatment: A True Experimental Study by Isa Ma’rufi, Khaidar Ali, Ign Arya Sedemen, P. Purwanto, Abu Khoiri

“…The result is the proportion of respondent classified in negative category in intervention group within week 0, week 1, week 2, week 3, and week 4 being 10.7%, 35.9%, 56.3%, 70.9%, and 90.3%, respectively. …”
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Spatial and Temporal Monitoring of North African Turtle Doves Streptopelia turtur arenicola (Hartert, EJO, 1894): First Migrants Arrive Early and Select Nesting Trees next to Forag... by Mohamed Mounir, Ismail Mansouri, Wafae Squalli, Soumaya Hammada, Mohamed Dakki

“…The first nests occurred in the second week of April, followed by the first eggs in the third week of April and the first chicks in the first week of May. …”
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