Challenges in managing osteogenesis imperfecta in a resource-limited setting: a case report by Ssekabembe Richard, Natumanya Robert, Vanusa Da Consolação Sambo, Abonga Daniel, Okidi Ronald

“…Case presentation A 3-week-old female neonate of African ethnicity was delivered at term by emergency C-section due to two previous scars. …”
Get full text

Patterns of Cell Activity in the Subthalamic Region Associated with the Neuroprotective Action of Near-Infrared Light Treatment in MPTP-Treated Mice by Victoria E. Shaw, Cassandra Peoples, Sharon Spana, Keyoumars Ashkan, Alim-Louis Benabid, Jonathan Stone, Gary E. Baker, John Mitrofanis

“…BALB/c mice were treated with MPTP (100–250 mg/kg) or saline either over 30 hours followed by either a two-hour or six-day survival period (acute model) or over five weeks followed by a three-week survival period (chronic model). …”
Get full text

Integrative mindfulness-based infant parenting program: theoretical foundations and a novel intervention protocol by Or Burstein, Zipi Teshale Zevin, Ronny Geva, Ronny Geva

“…The study delineates the theoretical foundations of this integrative mindfulness-based approach and openly provides a novel comprehensive protocol of an 8-week group intervention program that operationalizes the proposed framework. …”
Get full text

MoodMover: Development and usability testing of an mHealth physical activity intervention for depression by Yiling Tang, Madelaine Gierc, Henry La, Juehee Kim, Sam Liu, Raymond W Lam, Eli Puterman, Guy Faulkner

“…Objective This paper describes the early stages of the development process of MoodMover, a 9-week app-based intervention designed to promote PA for people with depression, including its usability testing. …”
Get full text

Evaluation of Contralateral Limb Cross Education and High-Frequency Repetitive Transcranial Magnetic Stimulation on Functional Indices of the Affected Upper Limb in Subacute Phase... by Katayoon Rezaei, Amin Kordi Yoosefinejad, Farzaneh Moslemi Haghighi, Mohsen Razeghi

“…Group “A” received physical therapy (PT) for 10 sessions, 3 times per week. Group “B” received PT and HF-rTMS as follows: stimulation of 20 Hz for 5 s, intertrain interval for 50 s, 20 trains, 2000 pulses at 90% resting motor threshold, and conventional PT. …”
Get full text

Mixed vitamin C and zinc diet supplements co-administered with artemether drug improved haematological profile and survival of mice infected with Plasmodium berghei by Felicia N. Ekeh, Nkiru E. Ekechukwu, Chimdinma F. Chukwuma, Ifeanyi Oscar N. Aguzie, Chinenye M. Ohanu, Chike Ebido, Stanley N. Oluah

“…Weight, packed cell volume (PCV), white blood cell count (WBC), red blood cell count (RBC), haemoglobin concentration (HB), and mortality were assayed weekly. The supplement improved PCV, HB, mean cell volume (MCV) and mean cell haemoglobin (MCH). …”
Get full text

Haemophagocytic Lymphohistiocytosis with Leptospirosis: A Rare but Devastating Complication by B. M. Munasinghe, A. G. Arambepola, N. Pathirage, U. P. M. Fernando, N. Subramaniam, S. Nimalan, T. Gajanthan

“…A 74-year-old farmer presented with high-grade, unsettling fever for a week. Muddy water exposure and suggestive symptoms prompted investigation and management in the line of leptospirosis (IV ceftriaxone was instituted, and later, MAT (microscopic agglutination test) became positive). …”
Get full text

Cytokines and Metabolic Patterns in Pediatric Patients with Critical Illness by George Briassoulis, Shekhar Venkataraman, Ann Thompson

“…The initial predominance of the hypometabolic pattern (48.6%) declined within 1 week of acute stress (20%), and the hypermetabolic patterns dominated only after 2 weeks (60%). …”
Get full text

Conductive Education as a Method of Stroke Rehabilitation: A Single Blinded Randomised Controlled Feasibility Study by Judith Bek, Melanie R. Brown, Jagjeet Jutley-Neilson, Nicholas C. C. Russell, Pia A. J. Huber, Catherine M. Sackley

“…Intervention group participants received 10 weekly 1.5-hour sessions of Conductive Education at the National Institute of Conductive Education in Birmingham, UK. …”
Get full text

Development and implementation of EcoDecibel: A low-cost and IoT-based device for noise measurement by Ling-Jyh Chen, Sakshi Saraswat, Fu-Shiang Ching, Chih-Yi Su, Hsin-Lan Huang, Wen-Chi Pan

“…The system was deployed across three environmental sites in Sanzhi District, Taiwan, for one week. Time-series prediction and forecasting models (SARIMA, Prophet, LSTM) were applied to the noise data to predict and forecast noise levels. …”
Get full text

Abrocitinib monotherapy in Investigator’s Global Assessment nonresponders: improvement in signs and symptoms of atopic dermatitis and quality of life by Andrew Blauvelt, Mark Boguniewicz, Patrick M. Brunner, Paula C. Luna, Pinaki Biswas, Marco DiBonaventura, Saleem A. Farooqui, Ricardo Rojo, Michael C. Cameron

“…Outcomes measuring skin clearance, itch, and quality of life were evaluated.Results Both nonresponders (n = 548) and responders (n = 260) treated with abrocitinib had rapid and clinically meaningful improvement in skin clearance, itch, and quality of life compared with placebo.Conclusion Patients with moderate-to-severe atopic dermatitis treated with abrocitinib who did not achieve an Investigator’s Global Assessment 0/1 response at week 12 still experienced rapid, clinically meaningful improvements across several other validated measures of efficacy and quality of life.ClinicalTrials.gov NCT02780167, NCT03349060, NCT03575871…”
Get full text

Human Keratinocyte Growth and Differentiation on Acellular Porcine Dermal Matrix in relation to Wound Healing Potential by Robert Zajicek, Vaclav Mandys, Ondrej Mestak, Jan Sevcik, Radana Königova, Eva Matouskova

“…After lifting the cultures to the air-liquid interface, the keratinocytes were stratified and differentiated within one week, forming an epidermis with basal, spinous, granular, and stratum corneum layers. …”
Get full text

Dietary Pyridoxine Requirements of Coho Salmon (Oncorhynchus kisutch) Post-Smolts by Hairui Yu, Xinyue Zhang, Ziyi Yuan, Leyong Yu, Youzhi Zhao, Lingyao Li

“…A 10-week feeding trial was conducted to investigate the dietary pyridoxine requirements of coho salmon (Oncorhynchus kisutch) post-smolts with an initial mean body weight of 180.22 ± 0.41 g. …”
Get full text

Rotigotine Objectively Improves Sleep in Parkinson’s Disease: An Open-Label Pilot Study with Actigraphic Recording by Giovanna Calandra-Buonaura, Pietro Guaraldi, Andrea Doria, Stefano Zanigni, Stefania Nassetti, Valentina Favoni, Sabina Cevoli, Federica Provini, Pietro Cortelli

“…This open-label pilot study aimed to objectively assess, by means of actigraphic recording, effect of rotigotine on sleep in PD patients with self-reported sleep complaints. 15 PD patients underwent one-week actigraphic recording before (T0) and during (T1) rotigotine treatment, which was titrated to the dose subjectively improving motor symptoms (4–8 mg/24 h). …”
Get full text

The relationship between career calling and presenteeism: the role of workaholism and self-compassion by Zhaobiao Zong, Feifei Sun, Haichao Sun, Shaoqing Su, Baojian Wei

“…By drawing on work as calling theory and self-compassion literature, we investigate the mediating role of workaholism and the moderating effect of self-compassion in the relationship between career calling and presenteeism.Methods A time-lagged cross-sectional questionnaire was administered in three waves, with two-week intervals between each wave. A total of 218 valid responses were collected from nurses working in three hospitals located in northern China. …”
Get full text

Patient Attitudes toward Gestational Weight Gain and Exercise during Pregnancy by M. L. Lott, M. L. Power, E. G. Reed, J. Schulkin, A. D. Mackeen

“…Women decreased the number of days per week they exercised (40.6% with 3 or more days prepregnancy versus 30.7% during pregnancy, P=0.002). …”
Get full text

Influence of Dapagliflozin on Glycemic Variations in Patients with Newly Diagnosed Type 2 Diabetes Mellitus by Feng-fei Li, Gu Gao, Qian Li, Hong-hong Zhu, Xiao-fei Su, Jin-dan Wu, Lei Ye, Jian-hua Ma

“…Primary outcome was the changes of mean amplitude glycemic excursion (MAGE) within groups. Results. After 24-week dapagliflozin therapy, our data showed the significant improvement of MAGE with dapagliflozin therapy (P=0.010). …”
Get full text

Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats by Lukáš Alán, Tomáš Olejár, Monika Cahová, Jaroslav Zelenka, Zuzana Berková, Magdalena Smětáková, František Saudek, Radoslav Matěj, Petr Ježek

“…Aiming to compare delta cell physiology/pathology of GK to Wistar rats, we found that delta cell number increased over time as did somatostatin mRNA and delta cells distribution in PI is different in GK rats. Subtle changes in 6-week-old GK rats were found. With maturation and aging of GK rats, disturbed cytoarchitecture occurred with irregular beta cells accompanied by delta cell hyperplasia and loss of pancreatic polypeptide (PPY) positivity. …”
Get full text

Comparison of two plates and screw osteosynthesis configurations in a rat model of critical sized femoral defects to reduce implant related failures by Marc Saab, Anne-Sophie Drucbert, Nicolas Blanchemain, Feng Chai

“…Radiographic evaluations, macroscopic and histologic assessments of the induced membranes were conducted at 1 week and 4 weeks. No implant failure occurred in Group 1 whereas in Group 2, 4/9 (44.4%) implant failures occurred during the follow-up (p = 0.03). …”
Get full text

The Effect of Music on the Happiness of Turkman Elderly in Day Care Centers by Zahra Sabzi, Razieh Saffar, Fatemeh Mehravar, Hamideh Mancheri

“…The intervention consisted of 12 group music therapy sessions, each lasting 45-50 minutes, three times a week, involving the playing of happy Turkman music. …”
Get full text