Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation by Katsuya Kobayashi, Toshio Suda, Haruhiko Manabe, Ichiro Miki

“…A marked proliferation of synovial fibroblasts in joints leads to pannus formation in rheumatoid arthritis (RA). Various kinds of cytokines are produced in the pannus. …”
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An optimized lightweight real-time detection network model for IoT embedded devices by Rongjun Chen, Peixian Wang, Binfan Lin, Leijun Wang, Xianxian Zeng, Xianglei Hu, Jun Yuan, Jiawen Li, Jinchang Ren, Huimin Zhao

“…Abstract With the rapid development of Internet of Things (IoT) technology, embedded devices in various computer vision scenarios can realize real-time target detection and recognition tasks, such as intelligent manufacturing, automatic driving, smart home, and so on. …”
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Integrative multi-omics analysis reveals the role of toll-like receptor signaling in pancreatic cancer by Jie Peng, Jiaao Sun, Youfeng Yu, Qihang Yuan, Yong Zhang

“…With the occurrence of pancreatic cancer, the TLR signal of various cell types gradually increased, but with the increase of the malignant degree of ductal epithelial cells, the TLR signal gradually weakened. …”
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Prognostic Factors of Liposarcoma in Head and Neck by Shuo DING, Zhigang HUANG, Jugao FANG, Yang ZHANG, Lizhen HOU, Wei GUO, Gaofei YIN, Qi ZHONG

“…However, an analysis of disease-specific survival rates revealed no significant differences across various factors (all P>0.05). ConclusionThe prognosis of head and neck liposarcoma is better compared to that of liposarcomas in other parts of the body. …”
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Reliability of nociceptive monitors vs. standard practice during general anesthesia: a prospective observational study by Daniel Widarsson Norbeck, Sophie Lindgren, Axel Wolf, Pether Jildenstål

“…Two commercially available nociception monitors, the PMD-200 from Medasense (NOL) and PainSensor from MedStorm (SCA), were used, and their data were collected along with various hemodynamic parameters. The three nociception monitoring techniques were compared during predetermined events. …”
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HAD-YOLO: An Accurate and Effective Weed Detection Model Based on Improved YOLOV5 Network by Long Deng, Zhonghua Miao, Xueguan Zhao, Shuo Yang, Yuanyuan Gao, Changyuan Zhai, Chunjiang Zhao

“…Future efforts will involve collecting more weed data from various agricultural field scenarios to validate and enhance the generalization capabilities of the HAD-YOLO model.…”
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Deficiency in Galectin-3 Promotes Hepatic Injury in CDAA Diet-Induced Nonalcoholic Fatty Liver Disease by Kazuhiro Nomoto, Takeshi Nishida, Yuko Nakanishi, Makoto Fujimoto, Ichiro Takasaki, Yoshiaki Tabuchi, Koichi Tsuneyama

“…It may be caused by alterations in the expression profiles of various hepatic genes including lipopolysaccharide-mediated inflammation.…”
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THE PROBLEM OF WORLD ORDER IN WESTERN IR STUDIES by M. V. Soljanova

“…Discussion of the structure of world order is underway in various countries, both at the state level and in the expert community. …”
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2D physically unclonable functions of the arbiter type by V. N. Yarmolik, A. A. Ivaniuk

“…It seems promising to further develop the ideas of constructing two-dimensional physically unclonable functions of the arbiter type, as well as experimental study of their characteristics, as well as resistance to various types of attacks, including using machine learning.…”
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A novel and efficient digital image steganography technique using least significant bit substitution by Shahid Rahman, Jamal uddin, Hameed Hussain, Sabir Shah, Abdu Salam, Farhan Amin, Isabel de la Torre Díez, Debora Libertad Ramírez Vargas, Julio César Martínez Espinosa

“…We tested a total of 165 different RGB images of various dimensions and sizes of hidden information, using various Quality Assessment Metrics (QAMs); A name of few are; Normalized Cross Correlation (NCC), Image Fidelity (IF), Peak Signal Noise Ratio (PSNR), Root Mean Square Error (RMSE), Quality Index (QI), Correlation Coefficient (CC), Structural Similarity Index (SSIM), Mean Square Error (MSE), Entropy, Contrast, and Homogeneity, Image Histogram (IH). …”
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Effects of refraction and axial length on the development and progression of diabetic retinopathy by M.M. Bikbov, O.I. Orenburkina, A.E. Babushkin, A.A. Fakhretdinova

“…This paper addresses studies on various aspects of DR in patients with myopia. It was demonstrated that DR arises, develops, and progresses in different ways under various axial lengths (AL). …”
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Lens disorders in degenerative myopia. Treatment options by M.H. Rabadanova, Zh.G. Oganezova, E.V. Kremkova, M.M. Yakh'yaeva

“…In addition to senile cataracts, its earlier development due to various risk factors (for example, degenerative myopia characterized by lens opacity even in low myopia) is also an issue. …”
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Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials by Weijie Fu, Maolin Zhao, Sheng Ding, Mei Xin, Ke Yang, Li Jiang, Fan Wu, Xiaochen Wu, Jian Wang, Jie Chen, Feng Gao, Siyi He

“…The present study intends to comprehensively compare the efficacy and safety of various anticoagulants in VTE.MethodsMedline, Embase, and Cochrane Library from their inception up to August 2023 were searched to compare the efficacy and safety of various anticoagulants in VTE. …”
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Agent-based modeling: Insights into consumer behavior, urban dynamics, grid management, and market interactions by Sambeet Mishra, Thiago Lima Silva, Lars Hellemo, Stefan Jaehnert, Lars Even Egner, Sobah Abbas Petersen, Tim Signer, Florian Zimmermann, Chiara Bordin

“…As the transition unfolds, new and diverse actors of various sizes will emerge in different segments. Thereby, the future energy system could shift its attention to the actors’ behavior than finding an optimum based on the physical system. …”
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A review on modified ZnO for the effective degradation of methylene blue and rhodamine B by Ommy Madina Abdul Halim, Nur Hafikah Mustapha, Siti Najiha Mohd Fudzi, Rahil Azhar, Nur Izzati Nabilah Zanal, Nurul Fatihah Nazua, Abu Hassan Nordin, Mohammad Saifulddin Mohd Azami, Mohd Azlan Mohd Ishak, Wan Izhan Nawawi Wan Ismail, Zuliahani Ahmad

“…This study focuses on the photodegradation of two pollutants, Methylene Blue (MB) and Rhodamine B (RhB) utilizing various dopants on zinc oxide (ZnO) as the photocatalyst. …”
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Queue Formation and Obstacle Avoidance Navigation Strategy for Multi-Robot Systems Based on Deep Reinforcement Learning by Tianyi Gao, Zhanlan Li, Zhixin Xiong, Ling Wen, Kai Tian, Kewei Cai

“…In contemporary society, the widespread application of robotics across various domains emphasizes the critical role of robotic systems in performing tasks that are too dangerous or complex for humans. …”
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Case study of natural convection topology optimization based on finite volume method by Honglei Liu, Shuzhe Guo, Ce Liu, Fei Du, Baotong Li, Jun Hong

“…This study applies natural convection topology optimization to various engineering cases, including 2D, 3D, inclined, and inverted heat sink with various boundary conditions. …”
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Unveiling the new chapter in nanobody engineering: advances in traditional construction and AI-driven optimization by Jiwei Liu, Lei Wu, Anqi Xie, Weici Liu, Zhao He, Yuan Wan, Wenjun Mao

“…Different library types, including immune, naïve, and synthetic/semi-synthetic libraries, offer diverse options for various applications, while display platforms like phage display, cell surface display, and non-surface display provide efficient screening of target Nbs. …”
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Safety and efficacy of omaveloxolone v/s placebo for the treatment of Friedreich's ataxia in patients aged more than 16 years: a systematic review by Ankita Umrao, Monika Pahuja, Nabendu Sekhar Chatterjee

“…Omaveloxolone (Omav) is an Nrf2 activator and has been reported to have antioxidative potential in various disease conditions. The present review was conducted to determine the use of Omav, the only FDA-approved treatment for FA. …”
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An Intelligent Crow Search Optimization and Bi-GRU for Forest Fire Detection System Using Internet of Things by Syed Abdul Moeed, Bellam Surendra Babu, M. Sreevani, B. V. Devendra Rao, R. Raja Kumar and Gouse Baig Mohammed

“…Several researchers have contributed different techniques to predict forest fires at various remote locations, highlighting the importance of innovative approaches in this field. …”
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