Health system costs of a breast cancer early diagnosis programme in a rural district of Rwanda: a retrospective, cross-sectional economic analysis by Lydia E Pace, Lawrence N Shulman, Jean Claude Mugunga, Parsa Erfani, Kayleigh Pavitra Bhangdia, Rashidah Nambaziira, Lysa Carolle Niteka, Jean Marie Vianney Dusengimana, John Ruhumuriza, Marie Louise Uwineza, Vestine Rugema, Cyprien Shyirambere, Melany Rabideau

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One-year outcomes of elderly acute cholecystitis patients by index treatment by Núria Lluís, Celia Villodre, Celia Villodre, Lucía Guilabert, Lucía Guilabert, Isabel de Castro, Isabel de Castro, Pedro Zapater, Pedro Zapater, Pedro Zapater, Pedro Zapater, Belén Martínez, Belén Martínez, José R. Aparicio, José R. Aparicio, Fèlix Lluís, Enrique de-Madaria, Enrique de-Madaria, Enrique de-Madaria

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Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

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A new future for dog breeding by Helle Friis Proschowsky, Maja Louise Arendt, Brenda N Bonnett, Camilla S Bruun, Irena Czycholl, Merete Fredholm, Dan O’Neill, James A Serpell, Peter Sandøe

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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

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Protocol for a systematic review and individual participant data meta-analysis for risk factors for lung cancer in individuals with lung nodules identified by low-dose CT screening by Matthew Callister, Harry J de Koning, Robert C Rintoul, Carolyn Horst, Arjun Nair, John K Field, Christine D Berg, Samantha Quaife, Rhian Gabe, Stephen Duffy, Sam Janes, Philip AJ Crosbie, Mark M Hammer, Panos Alexandris, Michael PA Davies

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Connotation, research status, and development directions of clean coal geology in China by Yuegang TANG, Shaoqing WANG, Xiaoshuai WANG, Xin GUO, Yafeng WANG, Liping XUE, Harold H. Schobert

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Cerebral Microhemorrhages in Children With Congenital Heart Disease: Prevalence, Risk Factors, and Association With Neurodevelopmental Outcomes by Kristen N. Andersen, Sicong Yao, Brian R. White, Marin Jacobwitz, Jake Breimann, Jharna Jahnavi, Alexander Schmidt, Wesley B. Baker, Tiffany S. Ko, J. William Gaynor, Arastoo Vossough, Rui Xiao, Daniel J. Licht, Evelyn K. Shih

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Additional Evidence for DDB2 T338M as a Genetic Risk Factor for Ocular Squamous Cell Carcinoma in Horses by Moriel H. Singer-Berk, Kelly E. Knickelbein, Zachary T. Lounsberry, Margo Crausaz, Savanna Vig, Nikhil Joshi, Monica Britton, Matthew L. Settles, Christopher M. Reilly, Ellison Bentley, Catherine Nunnery, Ann Dwyer, Mary E. Lassaline, Rebecca R. Bellone

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Lateral Extra-Articular Tenodesis as an Adjunct to ACL Reconstruction by Madeline M. McGovern MD, Sercan Yalcin MD, Natalie A. Lowenstein MPH, Jillian L. Mazzocca BA, Elizabeth G. Matzkin MD, Giovanna Medina MD, PhD

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Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: a population-based observational study protocol by Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Jeong Eun Min, Micah Piske, Julie Bruneau, U Siebert, P Todd Korthuis, Paxton Bach, B Carolina Guerra-Alejos, Megan Kurz, Laura M Dale, X Joan Hu, Kyle Kampman, Tom Loughin

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A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome by Kathleen Campbell, Jeffrey L. Neul, David N. Lieberman, Elizabeth Berry-Kravis, Tim A. Benke, Cary Fu, Alan Percy, Bernhard Suter, David Morris, Randall L. Carpenter, Eric D. Marsh, Jana von Hehn

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Enhanced Biomechanical Stability in Proximal Humeral Fractures: Finite Element Analysis of a Novel Endosteal Anatomical Support Nail for Improved Fixation in Elderly Patients by Jiawen Chen, Zhonghe Wang, Changda Li, Peiyu He, Zhongxuan Chen, Lijun Sun, Xiaoyan Cao, Na Tian, Xiang Dong, Peifu Tang, Hua Chen

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Effect of glucagon-like peptide-1 receptor agonists on vascular risk factors among adults with type 2 diabetes and established atherosclerotic cardiovascular disease by Aaron King, Xi Tan, Neil Dhopeshwarkar, Rhonda Bohn, Katherine Dea, Charles E. Leonard, Adam de Havenon

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Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…Gna Ahn,1,2,* Hyo-Won Yoon,1,* Ju Hwan Jeong,3,4,* Yang-Hoon Kim,1,* Woo-Ri Shin,1,5,6 Min-Suk Song,3 Ji-Young Ahn1 1Department of Microbiology, Chungbuk National University, Cheongju, Republic of Korea; 2Center for Ecology and Environmental Toxicology, Chungbuk National University, Cheongju, Republic of Korea; 3Department of Microbiology, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea; 4Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea; 5Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA; 6Department of Animal Bioscience & Integrated Biotechnology, Gyeongsang National University, Jinju, Republic of Korea*These authors contributed equally to this workCorrespondence: Ji-Young Ahn; Min-Suk Song, Tel +82-43-261-2301 ; +82-43-261-3778, Email jyahn@chungbuk.ac.kr; songminsuk@chungbuk.ac.krPurpose: Outer membrane vesicles (OMVs) derived from Gram-negative bacteria naturally serve as a heterologous nano-engineering platform, functioning as effective multi-use nanovesicles for diagnostics, vaccines, and treatments against pathogens. …”
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Osilodrostat treatment in patients with Cushing’s disease of Asian or non-Asian origin: a pooled analysis of two Phase III randomized trials (LINC 3 and LINC 4) by Akira Shimatsu, Beverly MK Biller, Maria Fleseriu, Rosario Pivonello, Eun Jig Lee, Rattana Leelawattana, Jung Hee Kim, Rama Walia, Yerong Yu, Zhihong Liao, Andrea Piacentini, Alberto M Pedroncelli, Peter J Snyder

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A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer by Veronica Rendo, Michael Schubert, Nicholas Khuu, Maria F. Suarez Peredo Rodriguez, Declan Whyte, Xiao Ling, Anouk van den Brink, Kaimeng Huang, Michelle Swift, Yizhou He, Johanna Zerbib, Ross Smith, Jonne Raaijmakers, Pratiti Bandopadhayay, Lillian M. Guenther, Justin H. Hwang, Amanda Iniguez, Susan Moody, Ji-Heui Seo, Elizabeth H. Stover, Levi Garraway, William C. Hahn, Kimberly Stegmaier, René H. Medema, Dipanjan Chowdhury, Maria Colomé-Tatché, Uri Ben-David, Rameen Beroukhim, Floris Foijer

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100 essential questions for the future of agriculture by Yuming Hu, Taolan Zhao, Yafang Guo, Meng Wang, Kerstin Brachhold, Chengcai Chu, Andrew Hanson, Sachin Kumar, Rongcheng Lin, Wenjin Long, Ming Luo, Jian Feng Ma, Yansong Miao, Shaoping Nie, Yu Sheng, Weiming Shi, James Whelan, Qingyu Wu, Ziping Wu, Wei Xie, Yinong Yang, Chao Zhao, Lei Lei, Yong‐Guan Zhu, Qifa Zhang

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Ascertainment and Verification of End-Stage Renal Disease and End-Stage Liver Disease in the North American AIDS Cohort Collaboration on Research and Design by Mari M. Kitahata, Daniel R. Drozd, Heidi M. Crane, Stephen E. Van Rompaey, Keri N. Althoff, Stephen J. Gange, Marina B. Klein, Gregory M. Lucas, Alison G. Abraham, Vincent Lo Re, Justin McReynolds, William B. Lober, Adell Mendes, Sharada P. Modur, Yuezhou Jing, Elizabeth J. Morton, Margaret A. Griffith, Aimee M. Freeman, Richard D. Moore

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Path analysis of factors influencing length of stay and hospitalisation expenses for oral cancer patients in tertiary hospitals in southeastern China: a cross-sectional study by Jing Wang, Chen Chen, Xiaoying Hu, Yi Fan, Yaping Wang, Yu Qiu, Qiujiao Yang, Mingming Xu, Yanfeng Weng, Yanni Li, Lisong Lin, Fa Chen, Baochang He, Fengqiong Liu

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