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  1. 5221

    Clinical and Radiographic Evaluation of Bone Profile Around Dental Implants Placed in the Esthetic Zone by Alssum L, Al-Kattan R, Al-Shibani N, Al Ali H, Aldossari F, Allam E

    Published 2025-02-01
    “…Lamees Alssum,1 Reem Al-Kattan,1 Nouf Al-Shibani,1 Hafsah Al Ali,2 Farah Aldossari,2 Eman Allam3 1Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia; 2College of Dentistry, King Saud University, Riyadh, Saudi Arabia; 3Research and Graduate Studies Department, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab EmiratesCorrespondence: Lamees Alssum, Department of Periodontics and Community Dentistry College of Dentistry King Saud University, Riyadh, Saudi Arabia, Email lalssum@ksu.edu.saObjective: To evaluate the bone profile around dental implants placed in the esthetic zone through periodontal assessment and radiographic analysis using cone-beam computed tomography (CBCT).Methods: We conducted a clinical observational study of 35 subjects who received dental implants placed in the esthetic zone to replace lost anterior teeth. …”
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  2. 5222

    Status of cerebrovascular autoregulation relates to outcome in severe paediatric head injury: STARSHIP, a prospective multicentre validation studyResearch in context by Shruti Agrawal, Claudia Smith, Stefan Y. Bogli, Michal M. Placek, Manuel Cabeleira, Deborah White, Esther Daubney, Adam Young, Erta Beqiri, Riaz Kayani, Diarmuid O'Donnell, Nazima Pathan, Suzanna Watson, Anna Maw, Matthew Ganrett, Hari Krishan Kanthimathianathan, Harish Bangalore, Santosh Sundararajan, Gayathri Subramanian, Dusan Raffaj, Avishay Sarfatti, Simona Lampareillo, Anton Mayer, Oliver Ross, Marek Czosnyka, Peter J. Hutchinson, Peter Smielewski, Carly Tooke, Caroline Payne, Holly Belfield, Amisha Mistry, Collette Spencer, Claire Jennings, Lara Bunni, Laura Anderson, Emily Morgan, Melanie James, Rebecca Beckley, Tahnima Khatun, Hafiza Khatun, Olivia Nugent, Richard Aldridge, Ruth Morgan, Julie Morcombe, Martin Quinton, Catherine Postlethwaite, Jenny Pond, Jessica Cutler, Caitlin Oxford

    Published 2025-03-01
    “…Methods: Studying Trends of AutoRegulation in Severe Head Injury in Paediatrics (STARSHIP) (clinicalTrials.gov identifier-NCT0688462), was a prospective, multicentre, observational, research database study conducted across 10 identified UK Paediatric Intensive Care Units from 01.07.2018 till 31.04.2024. The main objective was to validate and identify optimal thresholds of PRx associated with outcome (as assessed with Glasgow outcome scale extended for Pediatrics at 12 months) in children (<16 years) requiring invasive arterial blood pressure and intracranial pressure monitoring for TBI and establish a comprehensive research database. …”
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  3. 5223

    Distribution of Aeromonas bacterial population in water, sediment and Nile tilapia in fish culture pond, Guder, Ethiopia by Bekele Lema, Natarajan Pavanasam, Kassaye Balkew, Zufan Bedewi

    Published 2020-07-01
    “…The level of bacterial population in water, sediment and fish tissue were done by following standard methods and expressed as colony-forming units (CFU) in water per milliliter (CFU ml-1), sediment and fish tissues(CFU g-1).The results revealed more bacterial population in sediment (3.43 x106 to 5.54 x 106 CFU g-1) than in water (1.45x106 to 4.0x106 CFU ml-1) and  fish tissues (1.06 ± 1.10x104 to 1.74 ± 10.8x104 CFU g-1in gill filaments; 1.62 ± 11.2x104 to 2.82 ± 13.0x104 CFU g−1 in intestine from; and 0.82 ± 5.9x104 to 1.60 ± 12.1.6x104 CFU g-1; in kidney from 0.48 ± 5.0 to 0.77 ± 4.1x104 CFU g-1. in skin). …”
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  4. 5224

    An Insurance Value Modeling Approach That Captures the Wider Value of a Novel Antimicrobial to Health Systems, Patients, and the Population by Mei S. Chan, Richard Holloway, Robert King, Rosie Polya, Rebecca Sloan, Jack C. Kowalik, Tom Ashfield, Luke S.P. Moore, Thomas Porter, Jonathan Pearson-Stuttard

    Published 2023-07-01
    “…**Methods:** A novel mixed-methods approach was used to model insurance value in the United Kingdom: (1) literature review and multidisciplinary expert workshops to identify risk events for 4 relevant scenarios: ward closures, unavoidable shortage of conventional antimicrobials, viral respiratory pandemics, and catastrophic antimicrobial resistance (AMR); (2) parameterizing mitigable costs and frequencies of risk events across perspectives and scenarios; (3) estimating insurance value through a Monte Carlo simulation model for extreme events and a dynamic disease transmission model. …”
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  5. 5225

    Estimation of Health State Utility Values in Fabry Disease Using Vignette Development and Valuation by Derralynn Hughes, Andrew Lenny, Koonal Shah, Louise Longworth, Giovanna Devercelli, Olulade Ayodele

    Published 2023-04-01
    “…Each vignette was valued in an online survey by members of the United Kingdom (UK) general population using the composite time trade-off (TTO) method, which aims to determine the time the respondent would trade to live in full health compared with each impaired health state. …”
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  6. 5226

    A conceptual framework for the instructional design of a Moodle-based e-learning course for mainstreaming informal master’s education outcomes into ESP teaching in a formal non-lin... by Larisa M. Galchuk

    Published 2024-12-01
    “…This involves further development of the master’s systemic competencies and their deliberate transfer from formal to informal educational contexts while working with the learning resources of the lecture and project clusters within the thematic units of the online course. Their multifunctional assignments are crafted to effectively guide students towards productive, independent learning in informal settings, whether through direct, indirect, or subtle cues embedded within the task instructions. …”
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  7. 5227

    Cost Effectiveness of Insulin Glargine versus Neutral Protamin Hagedorn Insulin in the Treatment of Type 2 Diabetes Patients in Turkey by Ilhan Satman, Hayley Bennett, Candeger Yilmaz, Sazi Imamoglu, Goksun Ayvaz, Abdurrahman Comlekci, Demet Ozkaya, Toros Sahin

    Published 2013-08-01
    “…Improvements in glycaemic control have been incorporated using data from The Health Improvement Network (THIN) database in the United Kingdom, combined with meta-regression results describing the relationship between hypoglycaemia and glycaemic control. …”
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  8. 5228

    Costs of Potential Medication Wastage Due to Switching Treatment Among People With Multiple Sclerosis by Darin T. Okuda, Achal Patel, Robert Schuldt, Ibraheem Abioye, Nicole G. Bonine

    Published 2024-10-01
    “…**Objectives:** To estimate the cost associated with potential medication wastage (PMW) in a subcohort of PwMS receiving oral or self-injectable US Food and Drug Administration–approved DMTs who switched DMTs in a calendar year in the United States. **Methods:** This retrospective cohort study included adults with MS and used PharMetrics® Plus claims data from 2017 to 2021. …”
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  9. 5229

    MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS by Chunlai Yin, Xue Yan, Jinyi Ren, Cheng Zhang, Jiaqing Liu, Zilong Wang, Jing Liu, Weiping Li, Xia Li

    Published 2025-02-01
    “…The proliferation, apoptosis, differentiation and support for hematopoiesis of these cells were analyzed using CCK-8 assay, FC and induction medium and CFU (colony forming units) assay, respectively. Expression levels of metabolic molecules were used as indicators to screen MSCs with different metabolic pathways and were detected by RT-PCR and Western blotting. …”
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  10. 5230

    Factors Influencing the Uptake of Adolescents’ Sexual and Reproductive Health Services in Rubanda District, South Western Uganda. by Tayebwa, Amon

    Published 2023
    “…Conclusions and recommendations: The uptake of SRHS in the study was low and was attributed to age, sex, and residence; and there were suggestions that it could be improved by making the health facilities comfortable for adolescents, particularly by providing separate units and time for the consultations. The study recommends strengthening access to youth-friendly reproductive health services by according the adolescents the privacy they need.…”
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