3,5,6,7,8,3’,4’- Heptamethoxyflavonoid inhibits TGF-β1-induced epithelial–mesenchymal transition by regulating oxidative stress and autophagy through MEK/ERK/PI3K/AKT/mTOR signalin... by Yiting Wang, Zhiheng Ma, Weiwen Peng, Qinglian Yu, Wenjie Liang, Liu Cao, Zhuqiang Wang

“…Various experiments confirmed that HMF regulated the expression levels of Nrf2, keap-1, HO-1, ROS, MDA, SOD, GSH, and played a role in reducing oxidative stress. At the same time, HMF significantly activated autophagy by increasing expressions of Beclin-1 and LC3B as well as enhancing autophagosome content. …”
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Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea by Zishen Lin, Yue Feng, Jinping Wang, Zhaoyue Men, Xi Ma

“…Results Here, we reveal for the first time that core microbiota derived I3C represses gut epithelium glucuronidation, particularly 3β-glucuronic CDCA production, which reaction is mediated by host UDP glucuronosyltransferase family 1 member A4 (UGT1A4) and necessary of BA disorder induced diarrhea. …”
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The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant by S. A. Frolov, A. M. Kuzminov, V. Yu. Korolik, I. S. Bogormistrov, M. O. Chernozhukova, Sh. T. Minbayev

“…Its lowinvasiveness and minimal tissue traumatization provides decrease in postoperative morbidity rate and decreases patient rehabilitation time. At repeated administration of this method the recurrence rate decreases to 6% at preservation of anal sphincter function. …”
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STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment by Walter J Storkus, Ronald J Fecek, Manoj Chelvanambi, Jennifer L Taylor

“…Treated and control tumors were isolated at various time points to assess transcriptional changes associated with VN and TLS formation via quantitative PCR (qPCR), with corollary immune cell composition changes in isolated tissues determined using flow cytometry and immunofluorescence microscopy. …”
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Nouveaux éléments concernant l’amphithéâtre antique de Saintes (Charente-Maritime) : l’arène aux iiie et ive s. apr. J.-C. by Bastien Gissinger

“…Robin in collaboration with Inrap– at the time this article was written. Perhaps this study will bring further nuances to the data acquired from the partial exploration of the arena of this emblematic Julio-Claudian building.…”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…Assessment of patients with erosive form of GERD at endoscopic control during treatment revealed, that epithelialisation of esophageal erosions in medium age group took significantly longer time, than at young patients. GERD develops on a background of significant atrophic and inflammatory changes of gastric mucosa. …”
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Enhancing Arabic text-to-speech synthesis for emotional expression in visually impaired individuals using the artificial hummingbird and hybrid deep learning model by Mahmoud M. Selim, Mohammed S. Assiri

“…Natural Language Processing (NLP) and machine learning (ML) techniques provide powerful tools for analysing social media text data, helping detect emotional distress and providing timely support. By applying these technologies, AI-driven solutions can assist in understanding and addressing mental health concerns more inclusively. …”
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Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B by Qianqian Ma, Junzhao Ye, Ling Luo, Yanhong Sun, Wei Wang, Shiting Feng, Bing Liao, Bihui Zhong

“…Results A total of 1942 CHB patients were included (10–90% follow-up time 3–60 months), and 104 patients with elevated AFP (5.3%) and 27 patients with HCC development (1.4%) were identified during the follow-up. …”
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Attendance of Patients with ophthalmological problems about Eye Protection from UV/blue Light Radiation from Sun light and Electronic Devices in Sulaimani City by Salah Qadir Mahmood, Muhammad Babakir-Mina, Salar Ibrahim Ali, Abdulrahman M. Ibrahem, Bakhtyar Kamal Talabany

“…Ultraviolet (UV) and blue light are affecting eyes during the daily time and may cause many eye’s problems and diseases. …”
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Detection and subtyping of Blastocystis sp. in human and animal stool samples using high-resolution melting analysis by Ghodratollah Salehi Sangani, Ahmad Hosseini-Safa, Bibi Razieh Hosseini Farash, Pooria Salehi Sangani, Mehdi Zarean, Elham Moghaddas, Saeid Zoghdar Moghadam, Lida Jarahi, Ali Gholizadeh, Fariba Berenji

“…HRM analysis was then employed to identify and differentiate Blastocystis subtypes using specific primers via real-time PCR. Results Six subtypes were identified, with ST7 (30%) being the most prevalent, followed by ST3 (28%), ST2 (16%), ST1 (14%), ST5 (6%), and ST14 (6%). …”
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Vix (Côte-d’Or) et l’émergence des principautés celtiques : l’hypothèse portuaire et le concept de port of trade by Bruno Chaume

“…Even though Pauli’s theory has its weak points, it incites us to discuss the concept of port of trade, as defined by Polanyi, and to question Luc Baray’s application of this notion to the Celtic princely seats of the Late Hallstatt period, a time when the princely system was at its apogee. …”
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Sacral neuromodulation outcomes in the management of lower urinary tract symptoms in multiple sclerosis patients by Tyler Trump, Po-Ming Chow, Vivian Hua, Omer Anis, Mazen Mansour, Howard B. Goldman

“…Sustained treatment efficacy was recorded at time of last follow-up encounter based on the global response assessment (GRA) with <50% indicating decreased efficacy and >50% indicating sustained efficacy. …”
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Maternal and neonatal outcomes of Group B Streptococcus colonization: a retrospective study by Guixiu Jin, Lanhua Liu, Xiaolong Wang, Junling Fei, Zhenling Zhu, Ziyan Jiang, Min Liu

“…Pregnant women between 35 and 37 weeks of gestation had GBS screening using real-time polymerase chain reaction (RT-PCR). The clinical characteristics and outcomes of mothers and newborns were collected. …”
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Utilizing Hip Abduction Strength to Body-Weight Ratios in Return to Sport Decision-Making After ACL Reconstruction by Steven Higbie, Jacquelyn Kleihege, Brian Duncan, Walter R. Lowe, Lane Bailey

“…Clinical outcomes were assessed at the time of release to activity and included self-reported outcomes and a functional testing battery. …”
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Inter-individual Variability in Psychological Outcomes of Supervised Exercise in Adults with Type 2 Diabetes / Variabilidad interindividual en los efectos psicológicos del ejercici... by Marco Guicciardi, Romina Lecis, Davide Massidda, Lucina Corgiolu, Adelina Porru, Matteo Pusceddu, Francesca Spanu

“…Self-efficacy and perceived stress are related to barriers to exercise in T2DM, therefore the aim of this longitudinal study is to investigate variations across time and individual differences in both variables as effects of a supervised exercise training (6 months) in a small sample of persons diagnosed with T2DM. …”
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Tangeretin offers neuroprotection against colchicine-induced memory impairment in Wistar rats by modulating the antioxidant milieu, inflammatory mediators and oxidative stress in t... by Olalekan Bukunmi Ogunro, Mojisola Esther Karigidi, Gideon Ampoma Gyebi, Areej Turkistani, Ahmad H. Almehmadi

“…Conclusions These findings suggest that chronic administration of tangeretin at 50, 100, and 200 mg/kg, p.o. once daily, was protective in mitigating colchicine-induced cognitive impairment and associated oxidative stress. At the same time, donepezil hydrochloride did not demonstrate similar effects.…”
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Analysis of the predictive value of the prostate-specific antigen-to-neutrophil ratio for the diagnosis of prostate cancer by Yuxuan Chen, Haisheng Yan, Yaoqin Xu, Kexin Chen, Runqin Yang, Jiali Yang, Ruian Zhu, Rui Lin, Jiang Wang, Jie Liu, Pingsheng Gao, Lei Pang, Lexin Wang

“…Methods Patients were grouped in three different divisions of PSA 4–10 ng/ml, 10–20 ng/ml, > 20 ng/ml, We grouped the patients and compared the test data such as age, PSA, PSA-density (PSAD), and prostate-specific antigen-to-neutrophil ratio (PNR) between the two groups of patients who had puncture results of prostate cancer and non-prostate cancer at the same time using Log regression test to verify the diagnostic value of PNR. …”
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The Landbound Chicken and the Deliberate Chameleon yet have their Uses: Yorùbá Art History, Language, and Interpretation. by Kathy Curnow

“…Even when an artist and his patron live in the same community at the same time, their interpretations of a commissioned work may not be identical, so when one moves out to the analyses of art historians, Yorùbá or not, one cannot necessarily assume a third party will understand the work just as its maker and user did. …”
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DIGITAL TOOLS FOR MATCHING QUALIFICATIONS TO THE LEVELS OF THE NATIONAL QUALIFICATIONS FRAMEWORK by Volodymyr Kovtunets, Sergiy Londar, Serhii Melnyk, Oles Kovtunets

“…The novelty of the article is that for the first time in national and international practice, it proposes an alternative/supplementary algorithmic method for determining the level of certain full and/or partial professional qualifications by the National Qualifications Framework, thus creating prerequisites for further automation of the activities of professional standards developers. …”
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Rekayasa E-Aquaculture untuk Pemantauan Tambak Udang secara Realtime dengan Model Multipoint Node by Muhamad Komarudin, Hery Dian Septama, Titin Yulianti, Muhamad Aby Wicaksono

“…The farmer usually, monitor the shrimp pond manually that requires much greater time, effort and cost. The process can be automated with the Internet of Things (IoT) developed in this research. …”
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