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63141
Development and Evaluation of an Immunochromatographic Strip and a Magnetic Chemiluminescence Immunoassay for Detection of <i>Porcine Circovirus Type 2</i> Antigen
Published 2025-01-01“…On the premise of ensuring sensitivity, the most important feature of the immunochromatographic strip is that this method can save time when testing; results can be obtained within 5 to 10 min. …”
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63142
Meta-analysis of Therapeutic Effect in Depression Treatment of Repetitive Transcranial Magnetic Stimulation Combined Paroxetine
Published 2019-04-01“…Objective:To evaluate the therapeutic effect of repetitive transcranial magnetic stimulation(TMS)combined with paroxetine in the treatment of depression, provide reference for the clinical treatment and related research of depression.Methods:We electronically searched databases, including CNKI Chinese Journal Full-text Database, Wanfang Database, VIP Database, PubMed, the Cochrane Library and EMbase, to collect randomized controlled trials(RCTs)about depression treated by repetitive TMS combined with paroxetine. The time limitation was from the establishment of each database to 31st August 2017.Two reviewers independently screened literature, extracted data and assessed the risk of bias of the included studies. …”
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63143
Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro
Published 2025-02-01“…Enzyme-linked immunosorbent assays (ELISA) were used to assess the levels of pro-inflammatory cytokines, Fe2+, and associated oxidative stress indicators in the serum and cell supernatant. Real-time polymerase chain reaction (PCR), Western blot (WB), and immunofluorescence were used to find the expressions of related mRNAs and proteins in the lung tissue or A549 cells. …”
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63144
Deciphering the role of flutamide, fluorouracil, and furomollugin based ionic liquids in potent anticancer agents: Quantum chemical, medicinal, molecular docking and MD simulation...
Published 2025-01-01“…Molecular dynamics (MD) simulation reinforced the docking results by utilizing root mean square deviation (RMSD) values of [FT1]+ varies from 0.147387 to 0.539310 Å and [FM2]+ lies between 0.138098 Å and 0.583763 Å and root means square fluctuation (RMSF) values for [FT1]+ was 0.069428–0.298235Å and [FM2]+ 0.070097–0.364413Å provides insight into stability and the time-dependent atomic deviations. In addition, Ramachandran plots indicate that >90 % of residues occupy the favored regions supporting the protein structure stability. …”
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63145
Determination of a normal orogenic palaeo-geothermal gradient with clay mineral and organic matter indices: a review
Published 2024-09-01“…The observed correlation enables to determine gradual changes in metamorphic factors such as pressure, temperature and time causing sensitive shifts of the gradient slope in the range of normal gradients. …”
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63146
Efficacy, safety and cost-effectiveness of obinutuzumab in patients with follicular lymphoma: a rapid review
Published 2025-01-01“…The studies on obinutuzumab for FL were searched in full text with obinutuzumab, systematic review, meta-analysis, economics, cost, and health technology assessment as keywords, with a search time frame from the date of database creation to 29 November 2024. …”
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63147
Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study
Published 2025-01-01“…Multivariable regression explored the associations between quartiles of macronutrients (protein; carbohydrate; and total fat, including saturated, monounsaturated, and polyunsaturated fats), dietary components (sodium, potassium, dietary fiber, and sodium-to-potassium ratio), and sleep variables (total sleep time [TST], sleep latency [SL], and percentage of wakefulness after sleep onset [%WASO]). …”
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63148
Levels and related factors of occupational stress among nurses: hospital-based evidence from China, 2023
Published 2025-01-01“…In addition, workload and time pressure were rated highest among the sub-scales of the NJSS. …”
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63149
Severe soft tissue injuries in multiple trauma patients—a challenge we can meet? A matched-pair analysis from the TraumaRegister DGU®
Published 2025-02-01“…Concomitant soft tissue injuries represent a particular challenge, as they can lead to complications at any time of trauma care, hold a high risk of infection and often require multiple surgical interventions and interdisciplinary collaboration.MethodsThis retrospective, multicentric study used the TraumaRegister DGU® to examine the effect of open fractures and severe soft tissue injuries on outcome of multiple trauma patients. …”
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63150
The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae
Published 2025-01-01“…ObjectiveTo develop a machine learning-based prediction model to assist clinicians in accurately determining whether the detection of Klebsiella pneumoniae (KP) in sputum samples indicates an infection, facilitating timely diagnosis and treatment.Research methodsA retrospective analysis was conducted on 8,318 patients with KP cultures admitted to a tertiary hospital in Northeast China from January 2019 to December 2023. …”
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63151
The effects of altitude training on hormonal response in professional cyclists
Published 2025-01-01“…The increase in both testosterone and IGF-1 during the time course of the altitude sojourn suggests an anabolic stimulus linked to training adaptations. …”
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63152
Synthetic CB1 Cannabinoids Promote Tunneling Nanotube Communication, Cellular Migration, and Epithelial–Mesenchymal Transition in Pancreatic PANC-1 and Colorectal SW-620 Cancer Cel...
Published 2025-01-01“…Here, we investigated the in vitro effects of the synthetic CB1 cannabinoids AM-404, arvanil, and olvanil on human pancreatic PANC-1 and colorectal SW-620 cancer cell lines to understand further cellular behaviors and the potential risks of their use in cancer therapy. For the first time, the synthetic CB1 cannabinoids AM-404, arvanil, and olvanil significantly altered cancer cells in forming missile-like shapes to induce tunneling nanotube (TNT) communications in PANC-1 cells. …”
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63153
Effectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis
Published 2025-01-01“…However, VR training did not yield significant differences in gait speed, balance, or functional tests (Ten Sit-to-Stand Test, Five Sit-to-Stand Test, Sixty Sit-to-Stand Test, Timed Up and Go Test, and fatigue) compared with control groups. …”
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63154
Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naï...
Published 2024-12-01“…IgG and IgG subclass antibody responses to Na-GST-1 were measured by qualified indirect ELISAs at pre- and post-vaccination time points.<h4>Results</h4>Na-GST-1/Alhydrogel administered with or without CpG 10104 was well-tolerated. …”
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63155
MRI delta radiomics during chemoradiotherapy for prognostication in locally advanced cervical cancer
Published 2025-01-01“…Prognostic performance of the radiomic signatures, 2018 International Federation of Gynecology and Obstetrics (FIGO) stage (I–IV), and baseline MRI-derived maximum tumor diameter (Tumormax: ≤2 cm; >2 and ≤ 4 cm; >4 cm) was evaluated by area under time-dependent receiver operating characteristics (tdROC) curves (AUC) in cohortT and cohortV (AUCT/AUCV). …”
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63156
Preliminary clinical performance of a Cas13a-based lateral flow assay for detecting Neisseria gonorrhoeae in urine specimens
Published 2025-01-01“…Including the second forward primer reduced incubation time to 60 minutes. Using point-of-care DNA extraction, our Cas13a-based lateral flow N. gonorrhoeae assay demonstrated promising performance among clinical urine specimens.IMPORTANCEUsing a CRISPR-based assay we previously developed for Neisseria gonorrhoeae detection, we developed new techniques to facilitate point-of-care use. …”
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63157
Circumscribed choroidal hemangioma: clinical course and treatment
Published 2020-06-01“…Clinical presentations and OCT findings and their changes over time were assessed in 41 patients aged 31–83 years (mean age 51.0±2.22 years). …”
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63158
Testing an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study
Published 2025-01-01“…Electronic PROs (ePROs) offer a promising alternative by enabling real-time symptom tracking, which can facilitate early identification of issues, support shared decision-making, and improve outcomes for patients with TBI. …”
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63159
A Proposed mHealth Intervention to Address Patient Barriers to Colposcopy Attendance: Qualitative Interview Study of Clinic Staff and Patient Perspectives
Published 2025-01-01“…Participants were asked about colposcopy attendance barriers and perspectives on a proposed text message intervention to provide tailored education and support in the time between abnormal cervical screening and colposcopy. …”
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63160
Assessment of maternal healthcare services among the women of reproductive age in the rural municipality of Nepal: a cross-sectional study
Published 2025-02-01“…Similarly, women who were 18 years or above at the time of marriage were more likely to attend at least one PNC (AOR=3.2, CI=1.5–6.5) than women who were under 18. …”
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