Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study by Kim Dunleavy, Heidi Liss Radunovich, Jason M Beneciuk, Boyi Hu, Yang Yang, Janeen McCormick Blythe, Kelly K Gurka

“…Questionnaires will be administered at 3-month time points: baseline, pre- and postintervention, and at 3 and 6 months. …”
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Accuracy of noninvasive total haemoglobin measurement for detecting anaemia in infants: a cross-sectional study in a well-child care clinic, Khon Kaen, Thailand by Leelawadee Techasatian, Rattapon Uppala, Suchaorn Saengnipanthkul, Chamaiporn Tawiangnan, Prapassara Sirikarn, Sakuntala Supasai, Phanthila Sitthikarnkha

“…However, few infants attend anaemia screening programmes due to poor cooperation and being time-consuming. This study evaluated the accuracy of noninvasive total haemoglobin (Hb) spot-check monitoring as part of anaemia screening in healthy infants, compared with the conventional laboratory method.Design A cross-sectional study was conducted using a consecutive sampling technique.Setting The study was carried out at the Well-Child Clinic, Khon Kaen University, Thailand.Participants Healthy, full-term infants aged 6–12 months who were scheduled for vaccination. …”
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Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

“…Eight cytochrome P450 genes were analyzed for the expression level using quantitative real time-PCR. The cDNA of mosquitoes was amplified and sequenced for four fragments of vgsc gene. …”
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Meta Analysis on Rehabilitation Effect of Proprioception Training on Ankle Sprainof Athletes by Yuxiao CHEN, Jiaojiao LIU, Changsong Yi, Mengguang CHAI, Qing WANG, Lei JIANG

“…Objective:To explore the effects of proprioception training on the incidence of athletes' ankle sprains, dynamic neuromuscular control, postural stability and joint position perception.Methods:Data were searched from the databases of PubMed, Cochrane Library, EMbase, China National Knowledge Infrastructure(CNKI), Wanfang Database(Wangfang Data), Chinese Journal Full-text Database(VIP), China Biomedical Literature Database(CBMdisc).Athletes were included in the randomized controlled trials(RCTs)who were treated with proprioception training to improve the function of athlete's ankle joint.The retrieval time for each database was from the establishment of the database to December 31, 2019, and the references of related documents were traced.Two researchers independently searchered the literature, extracted data, and evaluated the quality of the literature.RevMan5.3 software was used to analyze the data.According to the systematic review manual provided by the Cochrane Collaboration Network, the continuous variables use mean difference(<italic>MD</italic>)and 95%confidence interval(<italic>CI</italic>)as indicators, and binary variables use risk ratio(RR)and 95%<italic>CI</italic> as indicators.The statistical heterogeneity was judged comprehensively by chi-square test(χ²test)and the Heterogeneity test(<italic>I</italic>²test).If <italic>P</italic>≥0.1 and <italic>I</italic>²≤50%, a fixed effects model would be used.In contrast, if <italic>P</italic>&lt;0.1 or <italic>I</italic>²&gt;50%, a random effects model would be used.Results:A total of 11 RCTs and 1 776 athletes were included.The results of Meta analysis showed that compared with the control group, the incidence of ankle sprains in the experimental group was significantly reduced after proprioceptive training[<italic>RR</italic>=0.61, 95%<italic>CI</italic>(0.41, 0.90), <italic>P</italic>=0.01]; compared with the control group, the posterolateral and posterior medical maximum extension distances of the experimental group increased significantly after proprioception training[<italic>MD</italic>=4.44, 95%<italic>CI</italic>(3.66, 5.23), <italic>P</italic>&lt;0.00 001;<italic>MD</italic>=4.21, 95%<italic>CI</italic>(3.18, 5.24), <italic>P</italic>&lt;0.00 001]and the difference was statistically significant;but there was no significant difference in the improvement effect of the anterior maximum extension distance, and the difference was not statistically significant(<italic>P</italic>&gt;0.05).The postural sway of the affected ankle joint in the experimental group was significantly lower than that in the control group;the athletes in the experimental group had better position perception ability in the ankle joint plantar flexion, dorsiflexion, middle and lateral directions than the control group.Conclusion:Proprioceptive training can effectively reduce the incidence of athletes' ankle sprains, improve dynamic neuromuscular control, improve postural stability, and enhance ankle joint position perception, which is worthy of clinical application.However, the absolute effect is not yet clear, so large samples and high-quality randomized controlled trials are still needed to further verify the efficacy of proprioception training, so as to provide more reliable evidence-based evidence for clinical rehabilitation.…”
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Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord by Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, Lukasz Cheda, Jacek Lenart, Krystyna Domanska-Janik, Anna Sarnowska

“…Replacement of the autologous or allogenic source of the bone-by-bone substitute could reduce the number of surgeries and time in the pharmacological coma during the reconstruction of the bone defect. …”
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Application of fourier transform infrared vibrational spectroscopy in identifying early biochemical changes in lipid profiles of individuals undergoing Roux-en-y gastric bypass by Amanda Motta de Bortoli, Márcia Helena Cassago Nascimento, Blanca Elena Guerrero Daboin, Beatriz Bobbio de Brito, Luiza Recla Pessotti, Paulo Roberto Filgueiras, Andressa Bolsoni Lopes, Valerio Garrone Barauna, Fabiano Kenji Haraguchi

“…Notably, serum triglycerides showed a significant correlation with the lipid-specific spectral region (1796–1685 cm− 1) at both time points (p < 0.05). Conclusion FTIR can effectively monitor biochemical changes in RYGB surgery patients. …”
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Effects of Replacing Inorganic Sources of Copper, Manganese, and Zinc with Different Organic Forms on Mineral Status, Immune Biomarkers, and Lameness of Lactating Cows by Manqian Cha, Xingjun Ma, Yunlong Liu, Shengyang Xu, Qiyu Diao, Yan Tu

“…Repeated-measure mixed models were used to evaluate the effects on trace mineral status over time. As the responses with the MHAC and AAC forms were similar, the treatments were also analyzed as organic trace minerals (OTMs, combining the MHAC and AAC groups, <i>n</i> = 40) versus inorganic trace minerals (ITMs, the S group, <i>n</i> = 20). …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca²⁺concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic>&lt;0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic>&lt;0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic>&lt;0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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Engagement féminin en Kabylie et intersection des revendications (1980-2001). Dominations, expériences et négociations identitaires by Margherita Rasulo

“…The processes of definition and negotiation of identity by women’s associations were expressed through a dialectical movement of appropriation and contestation of identity claims and gender identities with reference to social, legal and customary normative frameworks. At the same time, women’s and feminist claims were questioned within Kabyle identity associations. …”
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Thermal and packaging materials for enhancing the longevity and aroma integrity of fragrant rice during storage by Rajesh Chakraborty, Tuhin Suvra Roy, Jun-Ichi Sakagami

“…Retention of aroma for long time is the main bottleneck on the storage program of aromatic rice in Bangladesh. …”
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Risk factors for dengue mortality: a 7-year retrospective cohort in Honduras by Dilcia Sauceda-Acosta, Sandra Paola Paz Almendares, Elsy Cárcamo, Melba Zúniga-Gutiérrez, Briana Beltrán, María Félix Rivera, Marlon Meléndez Rodríguez, Judy Enamorado

“…Early identification of risk factors can help recognize patients who require close and timely clinical monitoring, which could improve outcomes in terms of reducing dengue mortality.…”
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Nisin A-producing Lactococcus cremoris formulations for pre- and post-milking teat disinfection modulate the bovine milk microbiota by Alessandra Gazzola, Camilla Ceccarani, Bianca Castiglioni, Filippo Biscarini, Stefano Morandi, Tiziana Silvetti, Renata Piccinini, Milena Brasca, Paola Cremonesi

“…Milk samples were collected from two selected healthy quarters of each cow at 3 time-points. Microbial communities were investigated by cultural and sequence-based methods, and analyzed through bioinformatic and statistical approaches. …”
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A dual-band microwave sensor for glucose measurements utilizing an enclosed split ring metamaterial-based array by Abhishek Kandwal, Ziheng Ju, Louis W.Y. Liu, Rohit Jasrotia, Choon Kit Chan, Zedong Nie, Ali M. Almuhlafi, Hamsakutty Vettikalladi

“…Overall, the log scale of the glucose concentration has exhibited a positive and linear correlation within the clinical diabetic range with both the resonant frequency shift at 4.5 GHz and the magnitude change at 9.2 GHz, thereby allowing the glucose concentration to be measured at 4.5 GHz and further cross-checked at 9.2 GHz at the same time.…”
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NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma by Chao-Yan Yao, Hang-Tian Tao, Jin-Jin He, Feng-Yi Zhu, Cui-Qing Xie, Yu-Na Cheng, Ji-Qin Li, Zhuang-Zhuang Liu, Chun-Yu Hou, Xue-Li Liu, Yong-Li Fan, Dong Fang, Xin-Rui Lv

“…Western blotting, immunofluorescence, real time PCR, and immunohistochemical staining were used to investigate the underlying mechanisms by which NUAK1 regulates PD-L1 expression in hepatocellular carcinoma. …”
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Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

“…Within each location, cows were randomly assigned to one of four treatments: (1 and 2) cows were estrus synchronized using the 7-day CO-Synch + CIDR protocol (7D) wherein they received an injection of one of two GnRH compounds [gonadorelin hydrochloride (GH) or gonadorelin diacetate tetrahydrate (GDT)] and a controlled internal drug release (CIDR) device on day 0, an injection of prostaglandin F2α (PG) at CIDR removal on day 7, and a second injection of their respective GnRH compound at fixed-time artificial insemination (TAI) on day 10 (7D-GH and 7D-GHT); (3 and 4) cows were treated with the 7&amp;7 Synch (7&amp;7) protocol, wherein they were treated the same as treatments 1 and 2 but received their CIDR inserts on day -7 in conjunction with an injection of PG (7&amp;7-GH and 7&amp;7-GDT). …”
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The Impact of Health Promotion Using Leaflet Media on Mothers&rsquo; Knowledge of the Early Stimulation of Toddlers&rsquo; Development and Growth by Shalahuddin I, Salsabila S, Rukmasari EA, Rosidin U, Eriyani T, Pebrianti S, Maulana I

“…The findings using the non-parametric in Wilcoxon Test, the significant values for respondents, particularly mothers with children ages 1– 1.5 a long time, 1.5– 2 years, and 2– 3 years, are 0.002, 0.000, and 0.000, respectively.Conclusion: In summary, before and after health education using leaflet media can increase mothers’ knowledge about stimulation of toddler growth and development in Gunung Tua the village, Subang Regency.Keywords: growth and development, leaflet, knowledge, stimulation, toddler…”
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Psychological peculiarities of professional development in late adulthood by E. F. Zeer, E. E. Symanyuk, A. A. Ryabukhina, G. I. Borisov

“…Scientific novelty. For the first time in developmental psychology, the relationship between motivation and quality of life at a later age is discussed; the most significant factors of professional development are analysed. …”
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A long-term drought reconstruction based on oxygen isotope tree ring data for central and eastern parts of Europe (Romania) by V. Nagavciuc, V. Nagavciuc, G. Helle, M. Rădoane, C.-C. Roibu, M.-G. Cotos, M. Ionita, M. Ionita

“…A <span class="inline-formula"><i>δ</i>¹⁸</span>O site chronology spanning 1803–2020 was compiled from seven individual time series. <span class="inline-formula"><i>δ</i>¹⁸</span>O values exhibited a significant negative correlation with moisture-related variables (cloud cover, relative humidity, and precipitation) and a positive correlation with temperature and sunshine duration. …”
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Immunosuppression and Outcomes in Patients with Cutaneous Squamous Cell Carcinoma of the Head and Neck by Doriana Iancu, Ana Fulga, Doina Vesa, Iuliu Fulga, Dana Tutunaru, Andrei Zenovia, Alin Ionut Piraianu, Elena Stamate, Corina Sterian, Florentin Dimofte, Mihail Alexandru Badea, Alin Laurentiu Tatu

“…</b> In this cohort of 68 subjects with cSCC, patients with immunosuppression had significantly lower overall survival, as well as lower three- and five-year survival rates compared with those without immunosuppression, even after adjustment for age, sex, stage, and previous surgical treatment. The median survival time for immunosuppressed individuals ranged from 11 to 21 months, varying based on their particular characteristics, and most critically, on the presence of other malignancies, while that of immunocompetent patients ranged from 18 to 51 months. …”
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Comparative Analysis of Multiple Hydrological Models in Assessing Climate Change Impacts on the Mille Watershed, Awash Basin, Ethiopia by Asmare Belay Nigussie, Mihiretie Ayana, Dessalegn Worku Ayalew, Gerawork Feleke, Asnake Enawgaw Amognehegn, Anteneh Yayeh Adamu, Andualem Endalew, Tewodrose Desale Meselaw, Shankar Karuppannan

“…Precipitation and temperature scenarios data were obtained using the CMhyd Tool and then bias-corrected using various methods based on the base time period (1985–2014). The projected annual rainfall is expected to increase by 8.91-18.68% and 8.09-18.65%, while the average temperature is projected to increase by 1.08–3.04°C and 1.59–4.05°C in the 2050s (2041–2070) and 2080s (2071–2100), respectively. …”
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