Early results of primary total hip arthroplasty performed in young adults at a regional Saudi-Arabian orthopedics center: a prospective observational study by Walid M. Al-Shaer, Ali H. Al-Yami, Mokhtar Ahmed Al-Sayed, Ali Mohammed Al-Zaidan, Emad Ruddah Al-Sufyani, Ahmed A. Khalifa, Raad M. M. Al-Thaqafi, Abdulmohsen H. Al-Hamyani, Mohammed M. Al-Subaie

“…Two (8%) patients had superficial wound infections at the time of suture removal, which were treated successfully by daily dressing and antibiotics. …”
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Decoding gene expression dynamics in planktonic and biofilm cells of Streptococcus mutans: regulation and role of mutanofactin genes in biofilm formation by Muhammad Afzal, Miguel Carda-Diéguez, Susanne Bloch, Susanne Bloch, Leon G. S. Thies, Alex Mira, Christina Schäffer

“…Specifically, the biosynthetic mutanofactin gene cluster was analyzed via quantitative real-time polymerase chain reaction.ResultsSeveral genes and operons were differentially expressed across the tested growth phases, with 1,095 genes showing differential expression between stationary-phase, planktonic and biofilm cells. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Furthermore, significant correlations were found between the parameters of circadian rhythm analysis, including nighttime activity, time of M10 and L5, and daytime and nighttime activitySD, and patient prognosis. …”
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Going, going, gone: Landscape drying reduces wetland function across the American West by J. Patrick Donnelly, Johnnie N. Moore, John S. Kimball, Kelsey Jencso, Mark Petrie, David E. Naugle

“…To improve our understanding of rapid ecosystem change, we reconstructed monthly wetland surface water hydrology in the western U.S. from 1984 to 2023 using cloud computing and ∼ 150,000 satellite images to measure shifts in the timing and duration of inundations. Monitoring encompassed all freshwater palustrine and littoral systems, including anthropogenic wetlands sustained through human water use (e.g., irrigated agriculture and earthen livestock ponds). …”
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Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology by Jiaying Yang MM, Yuancai Liu MM, He Yao MM, Mengying Sun MM, Yangbo Tong MM, Guanjun Ma MM, Zhuo Chen MD, Xiang Qian MD, Aiqin Zhang MD

“…When the patients developed radiotherapy-induced oral mucositis (at the time of 10F radiotherapy), and after 1 month of Dendrobium treatment (at the end of radiotherapy), the salivary flow rate was measured without stimulation to evaluate the degree of oral mucositis and the clinical efficacy. …”
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Extracellular vesicles from fifth-stage larval Angiostrongylus cantonensis upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocy... by Chien-Ju Cheng, Lian-Chen Wang, Lichieh Julie Chu, Kuang-Yao Chen, Ching-Yun Huang, Kuo-Lun Lan, Kuo-Yang Huang

“…Our results demonstrate for the first time the distinct protein compositions in A. cantonensis L5 and adult worm EVs. …”
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Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

“…Women were primarily from rural or tribal areas (1550/1684 (92.0%)) and lower economic strata (1177/1684 (69.9%)). Time from initial call to hospital arrival was longer for rural/tribal compared with urban patients (66 min (IQR 51–84) vs 56 min (IQR 42–73), respectively, p<0.0001). …”
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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

“…Methods Quantitative real-time PCR (qPCR) was employed to determine the expression levels of AGD1 and METTL13 mRNAs in PCSCs and exosomes. …”
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East Asian Welfare Regimes 東アジア福祉制度 by Joseph Wong, Andrew DeWit, Ito Peng

“…On top of that, the minimal role of leftist parties and their associated supports (such as trade unions) held back the construction of a full-fledged formation of the welfare state. At the same time, a focus on spurring economic development saw social policy subordinated to a larger productivist emphasis on fostering human capital while protecting the prerogatives of capital over labor.The authors draw insights from these lines of analysis, but view the region itself as a place of diversity. …”
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Temu Kembali Citra Tenun Nusa Tenggara Timur menggunakan Esktraksi Fitur yang Robust terhadap Perubahan Skala, Rotasi, dan Pencahayaan by Budiman Baso, Nanik Suciati

“…But MSER's computation time is 1.95 seconds faster than SURF which is 9.94 seconds. …”
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Modeling Lake Titicaca's water balance: the dominant roles of precipitation and evaporation by N. Lima-Quispe, D. Ruelland, A. Rabatel, W. Lavado-Casimiro, T. Condom

“…It was implemented in the Water Evaluation and Planning System (WEAP) platform at a daily time step for the period 1982–2016, considering the following terms of the water balance: upstream inflows, direct precipitation and evaporation over the lake, and downstream outflows. …”
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Pengkontruksian Bidirected Overlap Graph untuk Perakitan Sekuens DNA by Wisnu Ananta Kusuma, Albert Adrianus

“…To reduce the execution time suffix and prefix was converted into the single value so that the detection of overlap could be done by comparing the values. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…However, these techniques have either been time-consuming or have required separate calculation processes after collecting each parameter. …”
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Evaluating Whether Nonimmersion Virtual Reality Simulation Training Improves Nursing Competency in Isolation Wards: Randomized Controlled Trial by Dandan Zhang, MuLi Fu, Jianzhong Zhang, Yuxuan Li, Li Chen, Yong-Jun Chen, Zhefeng Zhong, Yin-Ping Zhang

“…Although NIVR simulation training does not significantly surpass traditional methods in imparting theoretical knowledge, it does reduce task completion time for specific activities. Its capacity for safe, repetitive practice and realistic scenario simulation makes NIVR a valuable tool in medical education. …”
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Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway by Zhou A, Feng HY, Fan CN, Wang J, Yuan ZY, Xu GH, Li CF, Huang WF, Yi LT

“…Our research aims to elucidate the potential antidepressant mechanisms of asiaticoside, a bioactive compound known for its neuroprotective and immunomodulatory properties.Methods: The antidepressant-like properties of asiaticoside in a model of chronic restraint stress (CRS)-induced depression in mice, with a particular focus on its interaction with ferroptosis-related pathways.Results: The behavioral results revealed that asiaticoside significantly ameliorated CRS-induced depressive symptoms, as evidenced by increased sucrose preference and reduced immobility time. At the molecular level, asiaticoside enhanced the expression of brain-derived neurotrophic factor (BDNF), phosphorylated tropomyosin receptor kinase B (pTrkB), phosphorylated nuclear factor erythroid 2-related factor 2 (pNrf2), glutathione peroxidase 4 (GPX4), and solute carrier family 7 member 11 (SLC7A11), indicating its neuroprotective and antioxidative effects. …”
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Characteristics and outcomes of out-of-hospital cardiac arrest among students under school supervision in Japan: a descriptive epidemiological study (2008–2021) by Kosuke Kiyohara, Mamoru Ayusawa, Masahiko Nitta, Takeichiro Sudo, Taku Iwami, Ken Nakata, Yuri Kitamura, Tetsuhisa Kitamura

“…Non-cardiac and traumatic cases were less likely to be witnessed at the time of arrest (46.2% and 42.0%, respectively) than cardiac cases (82.6%; p < 0.001). …”
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PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response by Tian L, Wang Z, Lei T, Feng L, Li Y, Wang K, Zhang Y, Zhang C, Liu J, Xing H, Ren W

“…A full-thickness burn wound injury model in 12 SD rats was established, and the therapeutic effect of PLL-g-HPA hydrogel combined with hUC-MSCs was detected by healing time/Histology/inflammation factor expression level.Results: The findings from SEM, FTIR, and HFF analyses demonstrated the successful synthesis of PLL-g-HPA hydrogels. …”
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Poutníci a jejich peníze na cestě do Říma. Zamyšlení nad edicí Il Libro del pellegrino (Siena, 1382–1446) by Roman Zaoral

“…The entries in the pilgrim book of Siena document that Florentine florins, Venetian ducats and Hungarian florins belonged to the most frequent gold specie in Italy that time, Prague and Flemish groschens occurred most often among silver coins. …”
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Remimazolam for the prevention of emergence agitation in adults following nasal surgery under general anesthesia: a prospective randomized clinical controlled trial by Yanfei Lu, Qiaomin Xu, Hong Dai, Jimin Wu, Mengting Ai, Haiyan Lan, Xiaoli Dong, Gongchen Duan

“…The secondary outcomes included the incidence of severe EA, anesthesia, surgery characteristics, adverse events, mean arterial pressure, and heart rate (at different time points). Results A total of 86 adult patients completed the study. …”
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Longitudinal impact of preregistration interprofessional education on the attitudes and skills of health professionals during their early careers: a non-randomised trial with 4-yea... by Ben Darlow, Jennifer Roberts, Patrick McHugh, Melanie Brown, Eileen McKinlay, Peter Gallagher, Lesley Gray, Gordon Purdie, Christine Wilson, Sue Pullon, Louise Beckingsale, Kaye Cheetham, Ruth Crawford, Sue Floyd, Janice Handley, Jackie Herkt, Lisa Kuperus, Alison Meldrum, Margot Skinner, Rose Schwass, Julie Weaver, James Windle, Lyndie Foster-Page

“…Mixed-model analysis of covariance, adjusting for baseline characteristics, compared scores between groups at each time point. Template analysis identified themes in free-text data.Results Mean ATHCTS scores for TIPE participants were 1.4 (95% CI 0.6 to 2.3) points higher than non-TIPE participants (p=0.002); scores were 1.9 (95% CI 0.8 to 3.0) points higher at graduation and 1.1 (95% CI −0.1 to 2.4) points higher 3 years postgraduation. …”
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