Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…Reductions in mean FMD [test group −3.43%; 95% confidence interval—CI [−2.68; 9.54], p = 0.487; control group −6.75%; 95% CI [1.29; 12.22], p = 0.012] and cIMT (test group −0.05 mm; 95% CI [0.01; 0.10], p = 0.014; control group −0.01 mm; 95% CI [−0.03; 0.05], p = 1.000) were observed in both groups from baseline to 6 months, without significant intergroup differences at any time-point. Differences between groups in serum inflammatory markers were detected at baseline and 3 days for interleukin (IL)-18, and at 10 days for IL-8.ConclusionPreliminary results from the present pilot study showed that steps 1 and 2 of periodontal treatment in subjects with periodontitis in stages III–IV and established cardiovascular disease induced improvements in cIMT and periodontal outcomes, although changes in FMD were not observed. …”
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Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019 by Stefanie Böhm, Volker Fingerle, Andreas Beyerlein, Manfred Wildner, Merle M. Böhmer

“…Even though a majority perceived checking for ticks after spending time outdoors, wearing long clothes, wearing closed shoes and tucking pants in socks as effective protection measures against tick bites, a much lower proportion applied those measures frequently (proportions perceived vs. applied: 99.2 % vs. 72.1%; 93.8 % vs. 40.2 %, 88.8 % vs. 51.1 % and 85.4 % vs. 16.8 %, respectively).Identified lack of knowledge or misconception regarding risk factors, availability of protection measures and tick behaviour may hamper application of recommended protection measures. …”
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Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization by Liangliang FAN, Limei REN, Song YANG, Wenjing LI, Yueming ZHAO, Ronghua ZHAO, Daqing ZHAO, Jiawen WANG

“…Methods: The CCK-8 assay was employed to detect the effect of GDNPs on the viability of macrophages (RAW264.7). Real-time quantitative PCR was utilized to detect the transcript levels of IL-6, iNOS, TNF-α, and MCP-1, which were indicators related to the M1 polarization of macrophages stimulated by GDNPs. …”
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Prevalence of AZFс Y chromosome microdeletions and association with spermatogenesis in Russian men from the general population by L. V. Osadchuk, G. V. Vasiliev, M. K. Ivanov, M. A. Prasolova, M. A. Kleshchev, A. V. Osadchuk

“…To identify AZF microdeletions, the presence/ absence of 15 STS markers was analyzed using multiplex real-time polymerase chain reaction. Age, weight, height, and the volume, concentration, total count, proportion of motile and morphologically normal spermatozoa in the ejaculate were recorded for all participants. …”
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Relationship of the gene pool of the Khants with the peoples of Western Siberia, Cis-Urals and the Altai-Sayan Region according to the data on the polymorphism of autosomic locus a... by V. N. Kharkov, N. A. Kolesnikov, L. V. Valikhova, A. A. Zarubin, M. G. Svarovskaya, A. V. Marusin, I. Yu. Khitrinskaya, V. A. Stepanov

“…The specificity of haplotypes, the discovery of various terminal SNPs confirms that the Khanty did not come into contact with other ethnic groups for a long time, except for the Nenets, which included many Khanty clans.…”
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Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets by Yuling Chen, Yan Li, Yuan Xu, Qing Lv, Yuanchun Ye, Jieruo Gu

“…The diagnostic value of the identified key genes was evaluated using ROC curves, logistic regression analysis, and a nomogram. Real-time PCR (RT-PCR) was used to quantified the expression of genes. …”
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Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout by Bourdon, Charlotte, Cachot, Jérôme, Gonzalez, Patrice, Couture, Patrice

“…The expression of genes involved in the antioxidant response (sod1, sod2, gpx), detoxification (cyp1a, mt1x, mt2x), Cu transport (ctr1, ctr2, slc11a2), energy metabolism (AcoAc, cox, 12S) and cell cycle regulation (bax) strongly decreased at Day 8 in the gills and at Day 16 in the liver of CuPT-exposed fish in comparison to controls at the same time point. This study clearly showed that the toxicity of Cu in the form of CuPT was much higher than that of ionic Cu from CuSO4and provides new information on the compound that will be useful to develop regulations concerning its use and release in the aquatic environment. …”
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Enhancing sustainable solid waste management through separate source collection by O. Arabiyat, J.T. Al-Bakri, F. Kölsch, S. Al-Omari, H. Aladwan

“…An overall assessment was carried out for the economic benefit of separate source collection.FINDINGS: Analyses of waste generation in the study area showed that the average quantity of municipal waste was 0.89 kilogram per capita per day, and there is a trend that shows an increase in municipal solid waste quantities with respect to time. A significant amount of municipal solid waste (60 percent) has an organic composition, while recyclable waste constitutes about 12.5 percent of the total municipal solid waste. …”
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Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke by XIE Qiurong, LIN Wanqi, ZHANG Qi, SHENG Bo, ZHANG Yanxin, HUANG Jia

“…Automated assessment of upper extremity motor function based on machine learning algorithms with markerless sensing techniques has focused on the Fugl-Meyer assessment of upper extremity (FMA-UE), Brunnstrom stages, and Wolf motor function test (WMFT) scales and has been proved with high-scoring accuracy and time efficiency. In addition, virtual reality (VR) training designed for neurorehabilitation can effectively promote recovery of upper limb function after stroke. …”
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Exploring under-five child malnutrition in Bangladesh: Analysis using the Extended Composite Index of Anthropometric Failure (ECIEF) by Farzana Akhter Bornee, Mohammad Rocky Khan Chowdhury, Badrun Naher Siddique, Baki Billah, Farjana Akter, Md Nazmul Karim

“…Continuous monitoring of the ECIAF over time would facilitate tracking changes in the prevalence of different forms of malnutrition, helping to plan interventions and assess the effectiveness of interventions aimed at addressing both undernutrition and overweight. …”
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Tailored BEST Exercise Protocol in Heart Failure Rehabilitation by Kevin Triangto, Basuni Radi, Bambang Budi Siswanto, Tresia Fransiska Ulianna Tambunan, Teuku Heriansyah, Alida Rosita Harahap, Aria Kekalih, Ade Meidian Ambari, Bambang Dwiputra, Dwita Rian Desandri, Hajime Katsukawa, Anwar Santoso

“…Poor responders also improved in chest expansion, sit-to-stand time, and postural balance, with minor 6MWT gains (407.33±72.50 meters). …”
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Un service de table en bronze et argent soigneusement rangé dans une cave à Reims/Durocortorum by Michaël Brunet, Fabienne Médard, Magalie Cavé, Stéphane Sindonino

“…The degree of alteration of the remains does not allow us to state with certainty the wealth of the domus to which this cellar belonged, but the proximity of three hypocausts, which were abandoned at the same time, suggests that it was associated with a comfortable Roman dwelling. …”
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To construct and validate a risk score model of angiogenesis-related genes to predict the prognosis of hepatocellular carcinoma by Duangui Gao, Yuan Lu, Tianpeng Jiang, Qinghong Duan, Zhi Huang

“…Finally, in the three pairs of HCC tissues and tissue adjacent to carcinoma by real-time fluorescent quantitative PCR (qRT_PCR) and western blotting (WB) to evaluate angiogenesis-related genes (ATP2A3 AEBP1 PNMA1, PLAT) expression level in HCC, and AEBP1 was knocked out in HCCLM3 cells, which is to study AEBP1 biological function in HCC. …”
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The Superiority of Removable Contact Splints in the Healing of Diabetic Foot during Postoperative Care by Vladimíra Fejfarová, Jaroslav Pavlů, Robert Bém, Veronika Wosková, Michal Dubský, Andrea Němcová, Alexandra Jirkovská, Bedřich Sixta, Karol Sutoris, Filip Thieme, David G. Armstrong, Eliška Vrátná, Jitka Hazdrová, Věra Lánská

“…., the number of healed patients, healing time, and duration of antibiotic (ATB) therapy) and secondary outcomes (e.g., number of reamputations and number and duration of rehospitalizations) with regard to the operation regions across all study groups. …”
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Genotyping of potato samples from the GenAgro ICG SB RAS collection using DNA markers of genes conferring resistance to phytopathogens by I. V. Totsky, I. V. Rozanova, A. D. Safonova, A. S. Batov, Yu. A. Gureeva, E. K. Khlestkina, A. V. Kochetov

“…Conducting a permanent phenotypic evaluation is associated with difficulties, for example, it is not always possible to work with pathogens, and phenotypic evaluation is very costly and time consuming. However, the use of DNA markers linked to resistance genes can significantly speed up and reduce the cost of the breeding process. …”
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The hydraulic performance and clogging characteristics of a subsurface drip irrigation system operating for five years in the North China plain by Li Zaiyu, Mo Yan, Gao Hao, Gong Shihong, Zhang Yanqun, Li Guangyong, Wu Feng

“…Owing to the well-designed pressure regulation and air exhaust system used in this SDI research, along with higher soil moisture in the crop root zone, the negative linear relationship between Dra and mc was most significant (p < 0.01). Based on time projection, this SDI system could operate normally for 8–11 years (Dra, Cu ≥ 80 %). …”
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A multidimensional assessment of adverse events associated with paliperidone palmitate: a real-world pharmacovigilance study using the FAERS and JADER databases by Siyu Lou, Zhiwei Cui, Yingyong Ou, Junyou Chen, Linmei Zhou, Ruizhen Zhao, Chengyu Zhu, Li Wang, Zhu Wu, Fan Zou

“…Noteworthy, unexpected signals not listed in the drug label were also identified, such as psychosexual disorders, prolactin-producing pituitary tumors, suicide attempt, and sudden death. The median onset time for all ADEs was 40 days. Furthermore, gender-based difference in risk signals was detected. …”
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New Approach to Improving the Prognosis of Ischemic Stroke by Regulating SCFAs with Acupuncture-Rehabilitation Therapy Based on Gut-Brain Axis by TANG Qiang, LIU Chong, CHAI Fanglei, ZHANG Jinpeng, LI Hongyu, ZHU Luwen

“…Inflammation plays an important role in the progression of stroke.The inflammatory response of ischemic stroke is a dynamic process,which occurs within a short time after ischemia and then affects the central nervous system. …”
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Pengembangan Automated Image Analysis untuk Menentukan Jumlah Bakteri Tahan Asam (BTA) pada Kasus Tubercolosis by Safri Adam, Puji Astuti, Puspa Amalia, Fadli Sukandiarsyah

“…However, in practice, manual calculations with a limited field of view on a microscope require a fairly long processing time. During the covid19 pandemic, the efficiency of daily diagnostic work including BTA examinations must be increased due to the limited ATLM personnel in the field who are also working to deal with Covid19. …”
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Association between lifestyle risk factors and mortality in the Mexico City prospective study by Paloma Ferrero-Hernández, Gary O’Donovan, Fanny Petermann-Rocha, Diego G. D. Christofaro, Carlos Cristi-Montero, Adilson Marques, Marcelo de Maio Nascimento, Claudio Farías-Valenzuela, Leandro F. M. Rezende, Gerson Ferrari

“…The magnitude of the associations increased as the exclusion of follow-up time increased after 2, 5, 10 and 15 years. There was a positive association between the number of lifestyle risk factors and all-cause and cause-specific mortality, showing the highest rate of respiratory, renal or hepatobiliary and all-cause mortality among participants with 4–5 lifestyle risk factors. …”
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