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60621
The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition
Published 2022-09-01“…Conclusions: The levels of OPN in human milk of Chinese mothers showed dynamic changes with the extension of lactation time. The OPN in human milk was related to the mother’s body composition but not related to related humoral factors.…”
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60622
Realizing low voltage-driven bright and stable quantum dot light-emitting diodes through energy landscape flattening
Published 2025-01-01“…Meanwhile, These LEDs show an unprecedented operation lifetime T95 (time for the luminance to decrease to 95%) of 72,968 h at 1,000 cd m-2. …”
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60623
Kidney transplant utilising donors after circulatory death: The first report from the African continent
Published 2024-04-01“…Thirty kidney transplants were performed, with a median (interquartile range) cold ischaemic time of 11.5 (8 - 14) hours. The incidence of DGF was 60.0%, and 30-day morbidity (other than DGF) was 20.0%. …”
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60624
Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction
Published 2025-02-01“…Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung allograft may already have occurred. …”
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60625
Impacts of benchmarking choices on inferred model skill of the Arctic–Boreal terrestrial carbon cycle
Published 2025-01-01“…Our results cover the overall time period of 1979–2019 and show that model scores can vary substantially depending on the data product applied, with higher model scores indicating better model performance against observations. …”
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60626
Abundant geographical divergence of Clostridioides difficile infection in China: a prospective multicenter cross-sectional study
Published 2025-02-01“…The positivity rate of toxigenic C. difficile using real-time fluorescence quantitative PCR test of feces was 10.2% (156/1528), and 125 (8.2%, 125/1528) strains were successfully isolated. …”
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60627
The succession of One Day Surgery with Breast Cancer Home Recovery Program by the National Cancer Institute (ODS BHR NCI) during the COVID-19 pandemic in Thailand
Published 2025-01-01“…In response to the need to hospital stays and minimize waiting time for surgery, particularly during the COVID-19 pandemic, the National Cancer Institute developed the One Day Surgery with Breast cancer Home Recovery program (ODS BHR NCI). …”
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60628
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD
Published 2020-01-01“…Then, from week 9 to week 16, some of these rats with COPD were subjected to real-time concentrated atmospheric PM2.5. Lung function, pathology, inflammatory cytokines, oxidative stress, and mucus and collagen production were measured. …”
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60629
Impact of water transfer on socioeconomic drought in China: A new approach based on production and consumption
Published 2025-03-01“…In 2017, the proportion of imported virtual water in regional consumption water increased significantly, accounting for 75.7 % in Beijing, 58.9 % in Tianjin and 46.1 % in Zhejiang. At the same time, the export regions provide remote support to the import regions by consuming local water. …”
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60630
Low & Anaplastic Grade Glioma Umbrella Study of MOlecular Guided TherapieS (LUMOS-2): study protocol for a phase 2, prospective, multicentre, open-label, multiarm, biomarker-direct...
Published 2025-02-01“…Introduction All grade 2/3 gliomas are incurable and at the time of inevitable relapse, patients have significant unmet needs with few effective treatments. …”
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60631
The Impact of Cementing Techniques on Implant Longevity in Relation to Keel Length in Persona and NexGen Knee Arthroplasty: A Comprehensive Study
Published 2025-02-01“…The modifications applied include better preparation of the bone surfaces and the cancellous bone cavities, pressurizing the cement and interstitial fluid suction at the same time, applying a layer of cement on the surfaces of the tibia and implant, and immobilizing the limb. …”
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60632
Fluctuations of anisotropic flow in Pb+Pb collisions at s NN $$ \sqrt{{\mathrm{s}}_{\mathrm{NN}}} $$ = 5.02 TeV with the ATLAS detector
Published 2020-01-01“…These cumulants provide information on the event-by-event fluctuations of harmonic flow coefficients vn and correlated fluctuations between two harmonics vn and vm. For the first time, a non-zero four-particle cumulant is observed for dipolar flow, v1. …”
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60633
Head-to-head comparison of pre-hospital qSOFA and lactate-qSOFA for predicting sepsis in patients with and without suspected infection. A multicenter prospective cohort study
Published 2020-02-01“…Conclusions An appropriate strategy for reducing the morbidity and mortality from sepsis must necessarily include the prompt identification of this time-dependent pathology by using all the tools at our disposal. …”
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60634
The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues
Published 2019-01-01“…Gene expression of the Reg family and cytokines (IL-6, IL-17, and IL-22) was evaluated by real-time RT-PCR, and Reg IIIβ/γ expression was examined by immunohistochemistry. …”
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60635
Overexpression of miR-124 enhances the therapeutic benefit of TMZ treatment in the orthotopic GBM mice model by inhibition of DNA damage repair
Published 2025-01-01“…In the mechanistic study, we for the first time identified that RAD51, a key functional molecule in DNA damage repair, is a novel and bona fide target of miR-124 in GBM cells. …”
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60636
Rapid identification of high-temperature Daqu Baijiu with the same aroma type by UV-VIS sensor of HBT combined with Zn2+
Published 2025-01-01“…Conclusions: This method not only improves the specificity of spectral detection, and the amount of information extracted from Baijiu samples, but also the detection time is shortened to less than 3 min, and the accurate identification of high-temperature Daqu Baijiu with the same aroma type was realized. …”
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60637
Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome
Published 2025-01-01“…Relative mitochondrial DNA (mtDNA) content and its oxidation level (8-oxoguanine, 8-OxoG) were determined in peripheral blood leukocytes by the SYBR Green method real-time PCR.ResultsOur findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …”
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60638
Identification of immune-associated genes with altered expression in the spleen of mice enriched with probiotic species using RNA-seq profiling
Published 2025-02-01“…On the other hand, 12 toll-like receptor genes underwent additional validation through quantitative real-time polymerase chain reaction (qRT-PCR), affirming the increased alignment between qRT-PCR and RNA-Seq findings. …”
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60639
Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro
Published 2025-01-01“…In the present study, we aimed to investigate the toxicity and underlying mechanisms of indole SCs JWH-018 and JWH-019 in mice (C57BL/6, male, 6–8 weeks old), zebrafish (AB strain, male, 4–5 months old) and modified human embryonic kidney (HEK) 293 T cells, using behavioral, pharmacokinetic, pharmacological approaches, and molecular docking. JWH-018 induced time- and dose-dependent cannabinoid-like effects in mice (administration dosages: 0.02, 0.1, and 0.5 mg/kg, i.p.), and yielded dose-dependent anxiogenic effects and lower aggression behavior in zebrafish (administration dosages: 0.01, 0.05, and 0.25 µg/g, i.p.), unlike JWH-019. …”
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60640
Preferences of people with type 2 diabetes for telemedical lifestyle programmes in Germany: protocol of a discrete choice experiment
Published 2020-09-01“…This study aims to examine the preferences of people with T2DM with respect to telemedical lifestyle programmes, to analyse whether these preferences predict programme success and to explore the changes that may occur during a telemedical lifestyle intervention.Methods and analysis We outline the protocol of the development and assessment of a discrete choice experiment (DCE) to examine patient preferences in a telemedical lifestyle programme with regard to the functions of the online portal, communication, responsibilities, group activities and time requirements. To develop the design of the DCE, we conducted pilot work involving healthcare experts and in particular people with T2DM using cognitive pretesting. …”
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