Fully Automated Production of (((<i>S</i>)-1-Carboxy-5-(6-([¹⁸F]fluoro)-2-methoxynicotinamido)pentyl)carbamoyl)-<span style="font-variant: small-caps">l</span>-glutamic... by Philipp Krapf, Thomas Wicher, Boris D. Zlatopolskiy, Johannes Ermert, Bernd Neumaier

“…<b>Results:</b> Overall, the new protocol enabled the production of [¹⁸F]JK-PSMA-7 in activity yields of 39 ± 4% (RCY = 58%) with an overall synthesis time of about 1 h. In a single production run with an initial activity of 36-43 GBq, 13-19 GBq of [¹⁸F]JK-PSMA-7 with a radiochemical purity of >99% was obtained. …”
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Impact of mindfulness-based tri-modal prehabilitation on functional recovery and selected surgical outcomes of patients with colorectal cancer admitted to surgical hospital wards:... by Bawantha Gamage, Manori Nayanakantha Gamage, Nilushika Madushani Perera, Chadani Samararatna Kodikara, Jayamina Udhara Munasinghe Wijeratne, S M D P Seneviratne Alles, Thavendra Kumaran, J M Chandima Jeewandara, Sanath Thushara Chamakara Mahawithanage

“…Outcomes will be measured at four different time intervals for each patient. Secondary outcome measures cover nutritional status, psychological status and selected biomarker status. …”
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Unveiling Low-frequency Eclipses in Spider Millisecond Pulsars Using Wideband GMRT Observations by Sangita Kumari, Bhaswati Bhattacharyya, Devojyoti Kansabanik, Rahul Sharan, Ankita Ghosh, Jayanta Roy

“…Moreover, for the first time, we detected an eclipse at a nonstandard orbital phase (∼0.5) for PSR J1810+1744, with a duration longer than the eclipse observed at superior conjunction. …”
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Effect of ocean acidification on the oxygen consumption of the sea urchins Paracentrotus lividus (Lamarck, 1816) and Arbacia lixula (Linnaeus, 1758) living in CO2 natural gradients by Robert Fernández-Vilert, Robert Fernández-Vilert, Vanessa Arranz, Vanessa Arranz, Marta Martín-Huete, Marta Martín-Huete, José Carlos Hernández, Sara González-Delgado, Sara González-Delgado, Rocío Pérez-Portela, Rocío Pérez-Portela

“…The study is divided into two parts: plasticity response over time, measuring respiration rates of individuals from the Mediterranean Sea exposed to low pH over seven days, and adaptation and plasticity under changing pH, analyzing individuals inhabiting a pH gradient in a natural CO2 vent system located in La Palma Island, Spain. …”
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Evaluation of the Safety of Percutaneous Dilational Tracheostomy Compared with Surgical Tracheostomy in the Intensive Care Unit by Yuta Suzuki, Takeshi Suzuki, Yuko Yamamoto, Ayano Teshigawara, Jun Okuda, Tomohiro Suhara, Tomomi Ueda, Hiromasa Nagata, Takashige Yamada, Hiroshi Morisaki

“…The length of ICU stay, time to tracheostomy from intubation, and the rate of mechanical ventilation and mortality at 28 postoperative days were also examined as secondary outcomes. …”
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Intense Pulsed Light Therapy with Optimal Pulse Technology as an Adjunct Therapy for Moderate to Severe Blepharitis-Associated Keratoconjunctivitis by Fang Ruan, Yunxiao Zang, Ruti Sella, Hongshuang Lu, Shang Li, Ke Yang, Tao Jin, Natalie A. Afshari, Zhiqiang Pan, Ying Jie

“…Efficacy outcome measures included meibum quality, Meibomian gland (MG) secretion function, eyelid margin signs, corneal fluorescein staining (CFS) score, noninvasive keratography breakup time (NIKBUT), ocular surface disease index (OSDI) score, Schirmer I test (SIT), classification of tear film lipid layer (TFLL), and Meibomian gland dropout (MGDR). …”
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Prenatal and neonatal factors for the development of childhood visual impairment in primary and middle school students: a cross-sectional survey in Guangzhou, China by Wen Sun, Lijuan Dai, Dunjin Chen, Lili Du, Bolan Yu, Juanjuan Chen, Jingsi Chen, Nali Deng

“…The following factors were significantly associated with an increased risk of VIUC: female gender, high birth weight, formula feeding, not having siblings, higher level of parents’ education, parental myopia, much homework time and little outdoor activity. Delivery mode was not associated with the risk of VIUC.Conclusions This study validates known major prenatal/genetic, perinatal and postnatal factors for childhood VIUC. …”
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Incremental Peritoneal Dialysis Favourably Compares with Hemodialysis as a Bridge to Renal Transplantation by Alessandro Domenici, Maria Cristina Comunian, Loredana Fazzari, Francesca Sivo, Angela Dinnella, Barbara Della Grotta, Giorgio Punzo, Paolo Menè

“…Age, gender, BMI, underlying nephropathy, residual renal function (RRF) loss rate before dialysis and RRF at RRT start, comorbidity, RRT schedules and adequacy measures, dialysis-related morbidity, Tx waiting time, RRF at Tx, incidence of delayed graft function (DGF), in-hospital stay for Tx, serum creatinine at discharge and one year later were collected and compared between patients on incremental PD or HD before Tx. …”
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A comparative bio-mechanical performance assessment of additively manufactured bone scaffolds using different beta Ti alloys and Gyroid based cellular structure by Mudassar Rehman, Yanen Wang, Kashif Ishfaq, Ray Tahir Mushtaq, Aqib Mashood Khan, Mohammed Alkahtani, Aamer Nazir, Maimoona Afzal

“…These processing conditions included laser power (200 W), scanning speed (1000 mm/s), hatch distance (0.065 mm), layer thickness (40 μm), and exposure time (50 μs). It was found that Ti-12Ta-23Nb-24Zr exhibited the highest compressive strength (864 MPa), near bone elastic modulus (45.2GPa), higher bone regrowth rate (111.6%), minimum process induced porosity (3.681%), and reduced surface roughness (0.462 μm), making it ideal for Orthopedic implants. …”
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Barriers and enablers to recruiting participants within paediatric perioperative and anaesthetic settings: lessons learned from a trial of melatonin versus midazolam in the premedi... by Marie C. Hyslop, Diana E. Papaioannou, Robert Bolt, Matthew J. Wilson, Michael Bradburn, Janet Clarkson, Esther Herbert, Nicholas Ireland, Jennifer Kettle, Amanda Loban, Amy C. Norrington, Christopher Vernazza, Christopher Deery

“…Results: Issues encountered included time sensitivity within pressured environments; feasibility of paediatric assent; research pharmacy availability; variation in anaesthetist equipoise; multifactorial decision-making issues in premedication selection; and the Associate Principal Investigator scheme being unable to support trials within anaesthetic trainee rotations. …”
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A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats by Pleydell, David R.J., Ndong Bass, Innocent, Mba Djondzo, Flaubert Auguste, Meta Djomsi, Dowbiss, Kouanfack, Charles, Peeters, Martine, Cappelle, Julien

“…The current results provide important insights for the design of future field studies aiming to detect Ebola viruses from sylvatic hosts, and can contribute to risk assessments concerning the timing of zoonotic outbreaks.…”
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An Integrated Electricity–Gas–Heat Energy System Based on the Synergy of Long- and Short-Term Energy Storage by Min Zhang, Jinhao Wang, Huiqiang Zhi, Jun Zhao, Xiao Chang, Shifeng Zhang, Xiangyu Guo, Tengxin Wang

“…The example shows that the configuration of the electrical–thermal hybrid energy storage system proposed in this paper leads to a significant improvement in the economy, with an increase in annual profit of CNY 3.78 million, or 22.96%. At the same time, environmental protection is significantly enhanced, and total annual carbon emissions are reduced by 7.4 tons, with a reduction of 19.23%.…”
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Instrumentation Removal following Minimally Invasive Posterior Percutaneous Pedicle Screw-Rod Stabilization (PercStab) of Thoracolumbar Fractures Is Not Always Required by Neil Manson, Dana El-Mughayyar, Erin Bigney, Eden Richardson, Edward Abraham

“…Operative outcomes of interest were operative room (OR) time, blood loss, and length of hospital stay. Follow-up variables of interest included patient satisfaction, Numeric Rating Scales for Back and Leg (NRS-B/L) pain, Oswestry Disability Index (ODI), and return to work. …”
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Improving Autonomous Vehicle Cognitive Robustness in Extreme Weather With Deep Learning and Thermal Camera Fusion by Mehmood Nawaz, Sheheryar Khan, Muhammad Daud, Muhammad Asim, Ghazanfar Ali Anwar, Ali Raza Shahid, Ho Pui Aaron HO, Tom Chan, Daniel Pak Kong, Wu Yuan

“…The object detection framework uses the modified version of the YoloV8 model, which exhibits high accuracy in real-time detection. In the YoloV8 model, we adjusted the network architecture to incorporate additional convolutional layers and altered the loss function to enhance detection accuracy in foggy and rainy conditions. …”
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Development of the relationship between visual selective attention and auditory change detection by Yuanjun Kong, Xuye Yuan, Yiqing Hu, Bingkun Li, Dongwei Li, Jialiang Guo, Meirong Sun, Yan Song

“…However, the evolution of these processes and their relationship over time remains unclear. In this study, we recorded electroencephalography signals from 118 participants (42 adults and 76 typically developing children) during separate visual localization and auditory-embedded fixation tasks. …”
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Targeting accuracy of neuronavigation: a comparative evaluation of an innovative wearable AR platform vs. traditional EM navigation by Marina Carbone, Marina Carbone, Nicola Montemurro, Nicola Montemurro, Nadia Cattari, Nadia Cattari, Martina Autelitano, Martina Autelitano, Fabrizio Cutolo, Fabrizio Cutolo, Vincenzo Ferrari, Vincenzo Ferrari, Emanuele Cigna, Emanuele Cigna, Sara Condino, Sara Condino

“…This ergonomic approach can facilitate a more intuitive understanding of spatial relationships and guidance cues, potentially reducing cognitive load and enhancing the accuracy of surgical gestures by aligning critical information with the actual anatomy in real-time. This study evaluates the benefits of a novel AR platform, VOSTARS, by comparing its targeting accuracy to that of the gold-standard electromagnetic (EM) navigation system, Medtronic StealthStation® S7®. …”
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Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics by Mikhail T. Silk, Nina Mikkilineni, Tarik C. Silk, Emily C. Zabor, Irina Ostrovnaya, Ari A. Hakimi, James J. Hsieh, Etay Ziv, Natasha Rekhtman, Stephen B. Solomon, Jeremy C. Durack

“…., formalin fixation and paraffin embedding (FFPE)) has been previously reported, little is known about the potential yield for molecular analysis at the time of biopsy sample acquisition. Objectives. Our objective was to improve the understanding of DNA and RNA yields from commonly used core needle biopsy techniques prior to sample processing. …”
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Phycospheric Bacteria Alleviate the Stress of Erythromycin on <i>Auxenochlorella pyrenoidosa</i> by Regulating Nitrogen Metabolism by Jiping Li, Ying Wang, Yuan Fang, Xingsheng Lyu, Zixin Zhu, Chenyang Wu, Zijie Xu, Wei Li, Naisen Liu, Chenggong Du, Yan Wang

“…We found that 0.1, 1.0, and 10 mg/L ERY inhibited the growth and chlorophyll of microalgae, but the microalgae gradually showed enhanced growth abilities over the course of 21 days. As the exposure time progressed, the nitrate reductase activities of the microalgae gradually increased, but remained significantly lower than that of the control group at 21 d. …”
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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…Significant predictors of migration included younger age, timing of marriage, and residency training status. …”
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PFOA, PFOS and PFHxS toxicokinetic considerations for the development of an in vivo approach for assessing PFAS relative bioavailability in soil by Albert L. Juhasz, Farzana Kastury, Ruby Jones, Mahima Seeborun, Tanya Caceres, Carina Herde, Michelle Cavallaro, Sarah Dilmetz, Joshua Hutchings, Yevgeniya Grebneva, Chris Desire, Peter Hoffmann

“…Following single dose administration (gavage) of ∼ 0.2–2000 µg kg−1 BW of PFOA, PFOS or PFHxS, differences in PFAS blood, organ and excreta concentrations were observed over 120 h although linear dose responses were determined for area under the blood plasma time curves (AUC; PFOA, PFHxS), liver accumulation (LA: PFOS) and urinary excretion (UE; PFOA, PFHxS). …”
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