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59881
MicroRNA-28-5p Regulates Liver Cancer Stem Cell Expansion via IGF-1 Pathway
Published 2019-01-01“…However, the role of miRNAs in liver CSCs has not been fully elucidated. Methods. Real-time PCR was used to detect the expression of miR-miR-28-5p in liver cancer stem cells (CSCs). …”
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59882
A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins
Published 2025-02-01“…Based on a high-resolution 2.91 Å CP model that was constructed for the first time, this degradation process is likely driven by hydrophobic interactions between tCuinter-bCDs and CP residues MET1, VAL5, THR55, and THR58, along with hydrogen bonds formed with THR4, VAL5, GLY15, PRO57, and ALA59, thereby promoting degradation of adjacent peptide segments. …”
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59883
Behaviour of post-tensioned benches made of high-content recycled aggregate concrete reinforced with racquet string fibres
Published 2024-12-01“…The use of glow-in-the-dark (GID) features into the benches in Series II enhanced their night-time visibility and visual appeal by up to 8 h. This research contributes towards the development of new applications for RAC with waste badminton racquet fibres, which can offer more sustainable solutions for the construction of urban furniture.…”
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59884
Challenges and adaptations in pancreatic cancer surgery during the COVID-19 pandemic in a high-volume center
Published 2025-01-01“…These findings underscore the importance of timely surgical interventions for cancer patients, even when the healthcare system is disrupted.…”
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59885
Aplicación de una herramienta avanzada de análisis de datos en el entorno de la construcción = Application of advanced data analysis tool in building environment.
Published 2022-12-01“…As a contribution, in this work raw time data series, obtained from a SCADA, are processed for further pattern construction of a building thermal facility. …”
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59886
SECONDARY PROPHYLAXIS OF VENOUS THROMBOEMBOLISM (VTE) WITH LOW DOSE APIXABAN OR RIVAROXABAN: RESULTS FROM A PATIENT POPULATION WITH MORE THAN 2 YEARS OF MEDIAN FOLLOW-UP
Published 2024-02-01“…The median low-dose DOACs administration time was 25.40 months (IQR 13.93-45.90). Twelve (3.7%) VTE recurrences were observed; 21 bleeding events were registered (6.5%), including one episode of MB (0.3%), 8 CRNMB (2.5%) and 12 minor bleeding (3.7%). …”
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59887
Gait characteristics in idiopathic normal pressure hydrocephalus: a review on the effects of CSF tap test and shunt surgery
Published 2024-12-01“…Studies were highly heterogeneous due to lack of standardization of CSFTT or shunt surgery methodology, with varying amounts of CSF removed during the tap test (20–50 ml) and varying time of outcome assessment after shunt surgery. Dynamic equilibrium measurements are generally used to assess preoperative levels of cardinal symptoms and postoperative outcomes in iNPH. …”
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59888
Standardization in the management of gram-negative bloodstream infections after implementation of a clinical care guideline at a large academic, safety-net institution: a quasi-exp...
Published 2025-01-01“…Results: The study included 147 patients pre-intervention and 169 post-intervention. Interrupted time series analysis showed a reduction in the median duration of therapy (–2.3 days, P = .0016), with a sustained decline (slope change –0.2103, P = .005) post-intervention. …”
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59889
Different rs-fMRI Data Processing Methods in the Study of Vascular Cognitive Impairment
Published 2019-02-01“…If it can be detected early and treated in time, it can effectively improve prognosis of patients with VCI.Resting state functional magnetic resonance imaging(rs-fMRI)is a spontaneous neuronal activity in different brain regions at rest in a resting state where the subject is quiet, lying, without movement, closed eyes or blinking, but does not enter sleep and has no systemic thinking activity. …”
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59890
Protocol for a mixed-methods randomised controlled trial evaluating the psychosocial effects of an expressive arts-based intervention on adults with age-related macular degeneratio...
Published 2024-12-01“…Participants will respond to a battery of measurements regarding their psychosocial condition at four time points: baseline (T0), 2 months after baseline (postintervention, T1), 5 months after baseline (T2) and 8 months after baseline (T3). …”
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59891
Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury
Published 2025-01-01“…P-Esbp demonstrated an extended half-life time in the bloodstream, and the polymer accumulated significantly in the liver, lungs, and kidneys within 4 h post injection. …”
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59892
Vascularized fibular grafting following tumor resection demonstrates acceptable long-term outcomes in Denmark: a national retrospective cohort study
Published 2025-01-01“…Results: The primary rate of graft union was 63%, and after secondary procedures the overall rate of graft union was 67%, with a median time to union of 13 months (IQR 9–17). The reoperation rate was 74%, while the limb salvage rate was 93%. …”
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59893
ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data
Published 2024-11-01“…The key process of the metastatic cascade is the epithelial-mesenchymal transition (EMT), which consists in the transformation of epithelial cells into mesenchymal, capable for migration. At the same time, epithelial markers (E-cadherin) are replaced by mesenchymal ones (N-cadherin, vimentin, fibronectin). …”
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59894
Comparative analysis of phytonutrients of Moringa oleifera leaves from South Africa and Nigeria, and their antimicrobial and antioxidant potentials by UPLC-ESI-QToF-MS and OPLS-DA...
Published 2025-01-01“…This study aimed to conduct a comparative analysis of the phytonutrients (nutrients protectors) or supplements, antioxidant, and antimicrobial potentials of M. oleifera leaves from Nigeria and South Africa to benchmark quality control protocols for commercial beverages such as Moringa porridge.MethodsStandard techniques, including high-performance liquid chromatography-photodiode array and ultra-high-performance liquid chromatography electrospray ionization quadruple time-of-flight mass spectrometry (UPLC-ESI-QToF-MS) and chemometrics orthogonal partial least square discriminant analysis (OPLS-DA) were employed for phytoconstituents fingerprinting. …”
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59895
Exclusive Breastfeeding and Associated Factors among Mothers with Twins in the Tamale Metropolis
Published 2020-01-01“…Biomedical (e.g. perceived onset of lactation, confidence of producing enough milk, parity, delivery place, delivery type, time of breastfeeding initiation) and bio cultural factors (e.g. family cooperation for current infant feeding, breastfeeding counselling) were also obtained. …”
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59896
Differences in central dopamine, but not serotonin, activity and welfare associated with age but not with preening cup use in commercial grow-out Pekin duck barns
Published 2025-01-01“…For DA turnover, there are differences in CM (p < 0.05) and DI (p < 0.001) over time, but no differences between PC and CON. The left hemisphere measured TPH1, TPH2, and TH. …”
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59897
Incidence of diabetic retinopathy and predictors among adult patients with diabetes in central and southern Ethiopia: a multicentre retrospective cohort study
Published 2025-01-01“…The Cox regression model was used to determine the median time to develop DR and identify predictors of DR. …”
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59898
In Vitro Evaluation of Leakage at Implant-Abutment Connection of Three Implant Systems Having the Same Prosthetic Interface Using Rhodamine B
Published 2014-01-01“…For each group, spectrophotometric analysis was performed to detect leakage with a fluorescence spectrophotometer at 1 h (T0) and 48 h (T1) of incubation time at room temperature. Results. Astra Tech had the highest inner volume (6.8 μL), compared to Dentium (4 μL) and Euroteknika (2.9 μL). …”
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59899
Comparison of combined suprascapular and axillary nerve pulsed radiofrequency and nerve block for the treatment of primary frozen shoulder: a prospective cohort study
Published 2025-12-01“…SPADI total scores were lower at 3 and 6 months after the procedure (p = 0.021 and 0.001). At different time after the procedure, most of the parameters of PROM improved more in group P than those in group B (flexion at 3 and 6 months, p = 0.042 and <0.001; abduction at 3 and 6 monthse, p = 0.001 and 0.001; extension at 3 and 6 months, p = 0.038 and 0.007, internal rotation at 6 months, p = 0.015; external rotation at 1, 3, and 6 months, p = 0.002, 0.002, and 0.001, respectively).Conclusions In patients with primary FS who completed both manipulation under anesthesia and intra-articular injections, PRF with SSN and AN appears to provide better pain relief, better PROM recovery, and more shoulder function improvement than nerve block treatment.…”
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59900
Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients
Published 2024-01-01“…Overall, SARS-CoV-2 infection elicits different levels of antibody response according to disease severity that declines over time and can be monitored using our homemade serological assays.…”
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