Les changements hydromorphologiques de l’estuaire de la Loire et l’évolution du port de Rezé/Ratiatum (Loire-Atlantique) by Rémy Arthuis

“…Many of the geomorphological features present in the Loire Valley, between the Roman port of Nantes/Condevicnum (Loire-Atlantique) on the right bank and that of Rezé/Ratiatum (Loire-Atlantique) on the left bank, appeared gradually between 5700 and 4500 BP, during the final Neolithic period. At that time, the marine influences which were dominating the Loire valley in Nantes, then a veritable ria, retreated after a slowing down of the sea level rise and gave way to a conquering river which incised the arms of Pirmil and the Madeleine. …”
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Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3 by Han Chu, Qi-Fei Deng, Yuan Fang

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).ConclusionsThis is the first time we found the expression of NLRP3 in cryptorchidism. …”
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Numerical Simulation of Multi-point Corona Discharge Characteristics in Thunderstorms by Xu Dewang, Tan Yongbo

“…In order to study characteristics of multi-points corona discharge in thunderstorm environments, a two-dimensional time-varying corona discharge model is used to simulate the process of multi-point corona discharge, and sensitivity tests are conducted. …”
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Integrating wide-swath altimetry data into Level-4 multi-mission maps by M. Ballarotta, C. Ubelmann, V. Bellemin-Laponnaz, F. Le Guillou, G. Meda, C. Anadon, A. Laloue, A. Delepoulle, Y. Faugère, M.-I. Pujol, R. Fablet, G. Dibarboure

“…<p>Real-time observation of ocean surface topography is essential for various oceanographic applications. …”
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Diagnoses of postpartum urinary retention using next-generation non-piezo ultrasound technology: assessing the accuracy and benefits by Ruben Plöger, Charlotte Behning, Adeline Walter, Ulrich Gembruch, Brigitte Strizek, Florian Recker

“…Especially covert postpartum urinary retention has a high number of missed diagnoses due to the lack of symptoms and the time-extensive diagnostics via ultrasound, leading to no treatment and no appropriate follow-up. …”
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Identification of compounds against atherosclerosis induced by ox-LDL based on cell extraction/UPLC–MS/MS from mulberry twigs and their mechanistic analysis by Zhihui Jin, Wei Xiang, Xiaowen Shi, Fenglin Jiang, Yanan Jia, Yuansong Zhang, Lingshu Zeng, Xianzhi Huang, Li Xu

“…Protective effects were assessed by measuring cell viability, malondialdehyde (MDA), and superoxide dismutase (SOD) levels, along with detecting intracellular reactive oxygen species (ROS) using 2, 7-dichlorodihydrofluorescein diacetate (DCFH-DA) and dihydroethidine (DHE) probes. Real-time qPCR and Western blotting were used for mRNA and protein level analysis. …”
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von Willebrand factor polymorphism (rs1063856) as a risk factor for portal vein thrombosis in chronic liver diseases by Isis Samy Bedira, Olfat M. Hendy, Moones Abdelaal, Ashraf A. Basuni, Asma Ebrahim Gaber Koshoo, Alzhraa Alkhatib, Sally S. Mandour

“…The identification of the vWF gene polymorphism (rs1063856) was assessed using real-time PCR. Results When comparing CLD patients with PVT to those without PVT and the healthy control group, there was a substantial rise in the vWF: Ag level. …”
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SNX30 inhibits lung adenocarcinoma cell proliferation and induces cell ferroptosis through regulating SETDB1 by Xinjie Fan, Qichu Zhu, Chengzhuo Du, Jinlai Chen, Yingming Su

“…Methods SNX30 levels in lung adenocarcinoma cell lines (A549 and HCC827) were determined using reverse transcription quantitative real-time PCR (RT-qPCR) or western blotting. Cell proliferation and apoptosis were assessed by CCK8 and flow cytometry, respectively. …”
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Evaluation of developmental competence of Sus scrofa domesticus (L.) oocyte-cumulus complexes after intra- and extraovarian vitrification by T. I. Kuzmina, I. V. Chistyakova

“…Differences were also observed in the level of MA between groups treated by EOV and IOV (89.4±7.5 µA and 149.2±11.3 µA, respectively, p ≤ 0.05). For the first time, pre-implantation embryos were obtained from oocytes treated by IOV.…”
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Application Value of STOP-Bang Questionnaire in Predicting Abnormal Metabolites by Pang Q, Han L, Li J, Xu L, Wang Y

“…Qingyi Pang,1 Li Han,1 Jun Li,2 Lingling Xu,1 Yueheng Wang3 1Department of Endocrinology, Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2Department of Endocrinology, Beijing Hepingli Hospital, Beijing, People’s Republic of China; 3Department of Ear, Nose and Throat, Beijing Hepingli Hospital, Beijing, People’s Republic of ChinaCorrespondence: Lingling Xu; Yueheng Wang, Email llxush@163.com; 8108374@qq.comObjective: To evaluate the application value of STOP-Bang questionnaire (SBQ) in predicting abnormal metabolites.Methods: Totally 121 patients were included into the study and filled the questionnaires, and their clinical data were collected at the same time. These patients were grouped according to the questionnaire scores. …”
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Effective BCDNet-based breast cancer classification model using hybrid deep learning with VGG16-based optimal feature extraction by Meenakshi Devi P., Muna A., Yasser Ali, Sumanth V.

“…The manual breast cancer diagnosis utilizes more time and is subjective. Also, the previous CAD models mostly depend on manmade visual details that are complex to generalize across ultrasound images utilizing distinct techniques. …”
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Assessing Electricity Supply Reliability by Detection of Anomalies in Daily Nighttime Light by Miaoying Chen, Yang Hu, Xin Cao, Shijie Li, Luling Liu

“…Finally, the spatial structure information of the angular effect is integrated to monitor the NTL anomalies over the time series. Anomalies with actual power outages were validated at 200 random points in Johannesburg, South Africa. …”
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Efficacy of Photobiomodulation Therapy Utilizing 808 nm and 660 nm Alone and in Combination for Treatment of Paresthesia in Rats by Ehsan Hajesmaelzade, Mohammad Mohammadi, Sina Kakooei, Luca Solimei, Stefano Benedicenti, Nasim Chiniforush

“…The rats were randomly assigned to six groups (<i>n</i> = 6) of (I) no-intervention (control), (II) no-laser, (III) 808 nm laser (250 mW, 4 W/cm², 20 s, 8 J/cm², (IV) 660 nm laser (150 mW, 0.25 W/cm², 32 s, 8 J/cm², (V) 808 nm plus 660 nm laser with the original settings, and (VI) 808 nm plus 660 nm laser with half of the time and energy density. After 16 days, a biopsy sample was taken from the nerve injury site and underwent histological, histometric, and immunohistochemical assessments. …”
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Regulation of MAP2, GFAP, and calcium in the CA3 Region Following Kainic Acid Exposure to  organotypic hippocampal slice culture [version 3; peer review: 2 approved] by Aulanni'am Aulanni'am, Kusworini Handono, Ettie Rukmigarsari, Hidayat Sujuti, Machlusil Husna

“…It is necessary to develop further research regarding regulation of calcium, MAP2, and GFAP at a spatial time after exposure to kainic acid and strategies to reduce damage caused by excitotoxicity.…”
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Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis by Termeh Sarrafan Sadeghi, Seyed AmirHossein Ourang, Fatemeh Sohrabniya, Soroush Sadr, Parnian Shobeiri, Saeed Reza Motamedian

“…Abstract Background Artificial intelligence (AI) methods, including machine learning and deep learning, are increasingly applied in orthodontics for tasks like assessing skeletal maturity. Accurate timing of treatment is crucial, but traditional methods such as cervical vertebral maturation (CVM) staging have limitations due to observer variability and complexity. …”
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Obesity prevalence among healthcare professionals in England: a cross-sectional study using the Health Survey for England by Richard G Kyle, Jane Wills, Catherine Mahoney, Louise Hoyle, Muireann Kelly, Iain M Atherton

“…Objective To estimate obesity prevalence among healthcare professionals in England and compare prevalence with those working outside of the health services.Design Cross-sectional study based on data from 5 years (2008–2012) of the nationally representative Health Survey for England.Setting England.Participants 20 103 adults aged 17–65 years indicating they were economically active at the time of survey classified into four occupational groups: nurses (n=422), other healthcare professionals (n=412), unregistered care workers (n=736) and individuals employed in non-health-related occupations (n=18 533).Outcome measure Prevalence of obesity defined as body mass index ≥30.0 with 95% CIs and weighted to reflect the population.Results Obesity prevalence was high across all occupational groups including: among nurses (25.1%, 95% CI 20.9% to 29.4%); other healthcare professionals (14.4%, 95% CI 11.0% to 17.8%); non-health-related occupations (23.5%, 95% CI 22.9% to 24.1%); and unregistered care workers who had the highest prevalence of obesity (31.9%, 95% CI 28.4% to 35.3%). …”
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Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA by Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

“…Sequential dd-cfDNA analysis showed dynamic changes in 25% of patients, all from the “true” dnDSA group, which tended to align with shifts in cumulative MFI over time.ConclusionThese findings highlight the correlation between cumulative dnDSA MFI and dd-cfDNA levels, particularly in HLA-DQ-directed dnDSA, and suggest graft injury is dynamic in dnDSA-positive patients. …”
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Comparative magnetic resonance imaging-based study of pelvic floor morphology and function before pregnancy and after primigravida vaginal delivery by Xiaonan Lin, Jinming Chen, Haijing Pan, Yaye Xu, Qun Zhong, Xueying Lin, Chengbin Ye

“…Conclusion Vaginal delivery can cause pelvic floor injury that may gradually recover over time. However, the injury does not fully recover to the pre-pregnancy level within 6mPP.…”
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Collection of SARS-CoV-2 Virus from the Air of a Clinic within a University Student Health Care Center and Analyses of the Viral Genomic Sequence by John A. Lednicky, Sripriya N. Shankar, Maha A. Elbadry, Julia C. Gibson, Md. Mahbubul Alam, Caroline J. Stephenson, Arantzazu Eiguren-Fernandez, J. Glenn Morris, Carla N. Mavian, Marco Salemi, James R. Clugston, Chang-Yu Wu

“…Abstract The progression of COVID-19 worldwide can be tracked by identifying mutations within the genomic sequence of SARS-CoV-2 that occur as a function of time. Such efforts currently rely on sequencing the genome of SARS-CoV-2 in patient specimens (direct sequencing) or of virus isolated from patient specimens in cell cultures. …”
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A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440 by Qifeng Wen, JinJin Chen, Jin Li, Ida Putu Wiweka Dharmasiddhi, Maohua Yang, Jianmin Xing, Yilan Liu

“…Using this system, we rapidly engineered P. putida for valencene biosynthesis for the first time, showcasing the system’s potential for expanding biotechnological applications.…”
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