Spectral and coupling characteristics of somatosensory cortex and centromedian thalamus differentiate between pre- and inter-ictal 5–9 Hz oscillations in a genetic rat model of abs... by Eleni Nikalexi, Vladimir Maksimenko, Thomas Seidenbecher, Thomas Budde, Hans-Christian Pape, Annika Lüttjohann

“…The present study characterizes the profile of 5–9 Hz oscillations in thalamo-cortical circuits during pre- and inter-ictal states.Here we recorded local-field-potentials in S1, CM and the secondary motor cortex of GAERS. Time-frequency analysis was used to assess spectral power and non-linear-association analysis was used to determine coupling strength and directionality between brain areas. …”
Get full text

Arthroscopic-assisted reduction for Developmental Hip Dysplasia (DDH) through the sub-adductor and anterolateral portals; A 24-month follow-up prospective descriptive study by Amr Samir Rashwan, Mahmoud El-Desouky, Hassan Elbarbary, Mahmoud Abd Elhamid Madbouly, Ahmed Khedr

“…Results The mean age of the included patients was 26.9 months. The mean operative time was 54.7 (36–90) minutes. Clinical assessment using the modified Severin classification revealed that 53 hips (77.9%) were grade I and 11 hips (16.2%) were grade II at the end of the follow-up. …”
Get full text

Effectiveness and utilization of a cognitive screening program for primary geriatric care by David P. Salmon, Anna Malkina, Melanie L. Johnson, Christina Gigliotti, Emily A. Little, Douglas Galasko

“…Abstract Background Effective detection of cognitive impairment in the primary care setting is limited by lack of time and specialized expertise to conduct detailed objective cognitive testing and few well-validated cognitive screening instruments that can be administered and evaluated quickly without expert supervision. …”
Get full text

The role of the left primary motor cortex in apraxia by Ksenia Perlova, Claudia C. Schmidt, Gereon R. Fink, Peter H. Weiss

“…Results Patients with and without M1 involvement did not differ in age and time post-stroke but in lesion size. When controlling for lesion size, the total apraxia scores did not differ significantly between groups. …”
Get full text

Trust Management in Social Internet of Things (SIoT): A Survey by Sana Alam, Shehnila Zardari, Shaheena Noor, Shakil Ahmed, Haralambos Mouratidis

“…Two trust-update schemes are discussed: time-driven and event-driven schemes, while most trust management models utilize an event-driven scheme. …”
Get full text

前列腺素E2体外可促进人CD34+ 细胞增殖 by 赖淑萍

“…【方法】 用mini-MACS免疫磁珠分选系统分选人CD34+细胞,并应用流式细胞术鉴定其纯度;将5 × 103/孔的CD34+细胞用不同浓度的dmPGE2及阴性对照无水乙醇干预后,用集落形成实验检测红系爆式集落形成单位(BFU-E)和粒-单核系集落形成单位(CFU-GM)形成情况;将1 × 106 /mL的CD34+细胞用不同浓度的dmPGE2及无水乙醇干预后,分别用流式细胞术检测细胞周期分布?real time-PCR检测survivin-mRNA水平?Western blot检测胞浆内β-catenin和survivin蛋白表达情况?…”
Get full text

Prognostic model and immune-infiltrating cell landscape based on differentially expressed autophagy-related genes in TP53-mutated multiple myeloma by Yan-Hua Zheng, Hong-Yuan Shen, Xiang Chen, Juan Feng, Guang-Xun Gao

“…Cox proportional hazard regression was employed to determine the independent prognostic ARG and construct a risk signature. Time-dependent receiver-operating characteristic (tROC) curve analysis was used to explore the predictive accuracy of the prognostic model. …”
Get full text

At what cycle threshold level are dogs able to detect SARS-CoV-2 in humans? by Víctor M Vidal-Martínez, Juan Manuel Mancilla-Tapia, Lilia C Soler-Jiménez, Iván Velázquez-Abunader, Matilde Jiménez-Coello, Antonio Ortega-Pacheco, David Hernández-Mena

“…Consequently, it is considered that using properly trained animals could offer a viable option to supplement existing diagnostic methods, allowing for rapid diagnosis while optimizing time and economic resources. Moreover, this approach is ecologically sustainable, as it generates less waste compared to the use of rapid tests, while continuing to confirm positive cases.…”
Get full text

Foundations of radar synthesis theory of phantom objects formation in SAR images by Volodymyr Pavlikov, Simeon Zhyla, Pavlo Pozdniakov, Denys Kolesnikov, Hlib Cherepnin, Olexandr Shmatko, Oleksii Odokiienko, Pavlo Malashta, Eduard Tserne

“…The following results were obtained: 1) the structure of the PhR is defined, which includes a receiver, a bank of SAR signal models, a bank of object models to be injected into the PhR signal, and a transmitter; 2) the parameters of the received SAR sensing signal that need to be estimated in the PhR receiver are determined; 3) the geometry of interaction in the “SAR-PhR” system is described, which allowed us to determine an expression for estimating the distance between SAR and PhR, as well as to estimate the distance-related parameters, such as signal delay time and characteristics of sensing signals. Conclusions. …”
Get full text

Our experience of buffalo improvement in India: last 50 years journey by T. K. Datta

“…There was a phase when the country’s milk production hit an all-time low, a mere 17 million Tonnes (mT) in 1950. …”
Get full text

Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis by E.A. Burylova, L.A. Mamaeva, A.S. Berdnikova, O.K. Fedorova

“…Multidisciplinary diagnostic and treatment approach to suspected sarcoidosis provides timely verified diagnosis and management strategy. …”
Get full text

A prospective, longitudinal, comparative analysis of the World Health Organization / International Committee of the Red Cross Basic Emergency Care Course on emergency medicine know... by Nichole Michaeli, Andrew Beck, Giovanna De Luca, Mary Gitau, Derek Lubetkin, Derick Ochieng, Grace W. Wanjiku, Justin G. Myers

“…Results The follow-up test scores were lower than the immediate post-course test scores, which suggests some knowledge loss over time. Compared to the control group, the BEC participants had higher test scores during the follow-up period although the difference was not significant. …”
Get full text

Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures by Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim

“…CGI methylation levels of 24 tumor suppressor genes were analyzed using methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA), pyrosequencing, and real-time polymerase chain reaction (PCR). Different CGI methylation patterns of CASP8, FHIT, and CHFR genes were identified in between early and late passages in some hESC lines. …”
Get full text

Safety and tolerability of intramuscular sotrovimab administered at different injection sites: results from the Phase 1 COSMIC study by Jennifer Moore, Alicia Aylott, Wen-Hung Chen, Jerzy Daniluk, Ian A. Hawes, Sergio Parra, Prosenjit Sarkar, Yasmin Sanchez-Pearson, Megan Turner, Amanda Peppercorn, Andrew Skingsley

“…Through Day 8, mean Pain-NRS values were < 1 and similar across injection sites; values were highest on Day 1 at 15 minutes post-dosing and decreased over time through Day 8. Injection site reactions were reported by all participants as ‘not at all’ or ‘a little’ bothersome. …”
Get full text

Minimally Invasive Parafascicular Surgery (MIPS) for Spontaneous Intracerebral Hemorrhage Compared to Medical Management: A Case Series Comparison for a Single Institution by Victoria L. Phillips, Anil K. Roy, Jonathan Ratcliff, Gustavo Pradilla

“…Cox proportional hazard models were used to estimate the time to inpatient death. Logistic regression analyses were used to determine treatment effects on secondary outcomes. …”
Get full text

Machine learning of Antarctic firn density by combining radiometer and scatterometer remote-sensing data by W. Li, S. B. M. Veldhuijsen, S. Lhermitte, S. Lhermitte

“…The regressor is first trained on time series of modelled density and satellite observations at randomly sampled pixels and then applied to estimate densities in dry-firn areas across Antarctica. …”
Get full text

A comparative study of analgesic effect between ultrasound-guided posterior vis-a-vis lateral transversus abdominis plane block in patients undergoing total abdominal hysterectomy... by Rajib Sikder, Sankar Roy, Arunava Biswas, Dipasri Bhattacharya

“…Results: VAS score was significantly less in Group P than in Group L (P<0.05). The time of first rescue analgesia requirement was longer in Group P compared to Group L. …”
Get full text

Predictive model of acute kidney injury in critically ill patients with acute pancreatitis: a machine learning approach using the MIMIC-IV database by Shengwei Lin, Wenbin Lu, Ting Wang, Ying Wang, Xueqian Leng, Lidan Chi, Peipei Jin, Jinjun Bian

“…In the test set, the GBM’s performance was consistent, with an area of 0.867 (95% CI, 0.831 to 0.903).Conclusions The GBM model’s precision is crucial, aiding clinicians in identifying high-risk patients and enabling timely interventions to reduce mortality rates in critical care.…”
Get full text

Isolated anti-SS-B (La) antibodies: rare occurrence and lack of diagnostic value by Xavier Mariette, Gaetane Nocturne, Pascale Chretien, Claire Goulvestre, Paul Cioni, Eric Ballot, Dounia Khelifi-Touhami

“…The initial anti-SS-B positivity does not correlate with a specific condition, both at the time of initial identification and after a 26-month follow-up period. …”
Get full text

Association between oral microbiome diversity and all-cause mortality: a longitudinal study of NHANES, 2009–2012 by Bo Lin, Liang Zheng, Wanna Chen, Ju Yu, Zhanqiang Zhang, Weiming Lv

“…Cox proportional hazards regression models were used to estimate the HR and 95% CI for all-cause mortality according to the quartiles of ASV number, adjusted for potential confounders.Results Among the 8224 participants (mean (SD) age: 42.0 (15.1) years; 49.9% male; 37.2% white, 23.8% black, 27.2% Hispanic and 11.8% other race/ethnicity), the median follow-up time was 108 months (IQR, 95–120 months) and 429 (5.2%) deaths were identified. …”
Get full text