Potential Strategies Applied by <i>Metschnikowia bicuspidata</i> to Survive the Immunity of Its Crustacean Hosts by Ji Zhang, Bingyu Li, Bingnan Zuo, Xiaodong Li

“…In addition, we applied multiple means to evaluate a series of candidate reference genes and found that <i>PMA1</i> in combination with <i>ACT1</i> is the most suitable choice for accurate normalization in quantitative real-time PCR (qRT-PCR) assays. Thus, we used this combination as the reference and performed qRT-PCR verification of several DEGs. …”
Get full text

Serum KL-6 levels reflect the severity of interstitial lung disease caused by immune checkpoint inhibitors by Xiaoping Li, Dan Xue, Qiongying Wei, Xuexue Tan

“…The lack of clear correlations with dosage, duration, or drug efficacy, coupled with nonspecific clinical manifestations, poses challenges in timely diagnosis and effective management. This study examined the association between ICIs-related ILD and serum levels of KL-6 and inflammatory markers in NSCLC patients. …”
Get full text

Quinoid to benzenoid transition-driven glutathione sensing: Dual-emission carbon dots and smartphone-based ratiometric fluorescence analysis by Al-Montaser Bellah H. Ali, Ashraf M. Mahmoud, Yousef A. Bin Jardan, Aya M. Mostafa, James Barker, Mohamed M. El-Wekil

“…This mechanism, utilized for the first time in GSH detection, offers a distinct advantage over previous methods that primarily relied on GSH's complexation capabilities. …”
Get full text

Refining α-synuclein seed amplification assays to distinguish Parkinson’s disease from multiple system atrophy by James A. Wiseman, Clinton P. Turner, Richard L. M. Faull, Glenda M. Halliday, Birger Victor Dieriks

“…Early diagnosis of MSA is problematic, and seed amplification assays (SAAs), such as real-time quaking-induced conversion (RT-QuIC), offer the potential to distinguish these diseases through their underlying α-synuclein (α-Syn) pathology and proteoforms. …”
Get full text

Usefulness of Magnetoinertial Wearable Devices in Neurorehabilitation of Children with Cerebral Palsy by Marco Iosa, Manuela de Sanctis, Aurora Summa, Elena Bergamini, Daniela Morelli, Giuseppe Vannozzi

“…After neurorehabilitation, this last parameter increased more in CPI (35%) than in CPB (6%, p=0.017 for the interaction group per time). The results of the questionnaires showed that therapists agreed with the usability (100% judged it as “easy to use”) and usefulness of the MIMU-based assessment in defining patient-oriented interventions (87%). …”
Get full text

Stress assessment instruments for hospitalized preterm newborns: scoping review by Mónica Costa, Maria Filomena Gaspar, Maria Alice Curado, Ana Brantes

“…The preterm newborn must be observed in a systematic and structured way, before, during and after any intervention, aiming at the correct assessment and interpretation of his behaviour and signs of stress, and at the timely planning of interventions that minimize and prevent stress. …”
Get full text

Cell-free supernatants from plant growth-promoting rhizobacteria Bacillus albus strains control Aspergillus flavus disease in peanut and maize seedlings by Lai Loi Trinh, Kim Ngoc Le, Hoang Anh Le Lam, Hoai Huong Nguyen

“…These were characterized using rapid chemical assays and ultra-high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight/mass spectrometry (UHPLC-ESI-QTOF/MS), combined with bioinformatic tools such as Global Natural Product Social Molecular Networking (GNPS) and Natural Products Atlas (NPAtlas). …”
Get full text

The role of the Kazan school of journalistic education in the training of national journalists by V.Z. Garifullin

“…The first half of the 1990s was a rather difficult but interesting time for the sphere of higher education. We have begun to search for the optimal system of educational process, which would significantly improve the professional training of journalists and meet the new needs that have arisen in the information market of the country in connection with the sharp transformation of the socio-political system. …”
Get full text

Development and investigation of common wheat lines of winter cultivar Bezostaya 1 with combinations of dominant alleles of VRN-1 loci by E. V. Chumanova, T. T. Efremova, Y. V. Kruchinina, L. A. Pershina

“…The unequal influence of different alleles of VRN-1 loci on the duration of the growing period has also been shown; however, there is little information on the effect of the combination of different alleles on heading time. In developing genotypes having different alleles of dominant VRN genes on the base of the same genetic background, it is necessary to study the genetic effects of VRN genes on the duration of the growing season and the individual developmental phases, as well as on productivity. …”
Get full text

Maternal and Perinatal Outcomes of Pregnancies with Uterine Leiomyomas by Caner Kose, Busra Korpe, Tugba Kinay, Seval Yilmaz Ergani, Rahmi Sinan Karadeniz, Ali Turhan Caglar, Yaprak Engin Ustun

“…It was found that cases with leiomyomas ≥7 cm, compared to those with <4cm, had deliveries at earlier gestational weeks (36w6/7±2d vs. 37w+6/7±2d, p=0.018) and had lower newborn birthweight (2849.44±516.74 g vs. 3237.5±350.6 g, p<0.001), longer operation time (105.92±34.78 min vs. 68.21± 22.31 min, p<0.001) and a higher rate of neonatal intensive care unit requirement (48.1% vs. 13.7%, p<0.001). …”
Get full text

Excerpts from The Freedom Fight: A Novel of Resistance and Freedom. by Pamela J. Olubunmi Smith

“…Thirdly, since its publication in 1970, it has withstood the test of time as the premier example of “ìjìnlẹ̀ Yorùbá.”     …”
Get full text

ارزیابی بیان فاکتور رشد عصبی (Nerve Growth Factor) NGF در مغز نوزاد موش صحرایی به دنبال مواجهه با پرفلئورواکتانویک اسید... by ستار دوغی, زین العابدین شریفی دستجردی, ناظم قاسمی

“…در گروهای دریافت‌کننده‌ی PFOA، این ترکیب بصورت روزانه گاواژ گردید. 20 روز بعد از زایمان، مغز موش‌های نوزاد خارج شده و با استفاده از روش‌های ELISA و Real Time PCR، بیان فاکتورهای رشد عصبی مورد بررسی قرار گرفت.یافته‌ها: نتایج نشان داد که میانگین بیان ژن NGF در گروه‌های دریافت‌کننده‌ی PFOA و بویژه در گروه mg5PFOA/ نسبت به سایر گروه‌ها افزایش معنی‌داری داشت (0/001 ≥ P). …”
Get full text

丙酮酸乙酯抑制脓毒症时HMGB1释放的分子机制

“…激光共聚焦显微镜观察培养细胞内p-p38MAPK?NF-κB和CBP的变化;Real-time PCR检测培养细胞HMGB1的mRNA水平,ELISA检测培养上清HMGB1的蛋白含量?…”
Get full text

Survival Status and Predictors of Mortality among Newborns Admitted with Neonatal Sepsis at Public Hospitals in Ethiopia by Samuel Dessu, Aklilu Habte, Tamirat Melis, Mesfin Gebremedhin

“…The Kaplan-Meier survival curve together with log-rank test was used to estimate the survival time of the neonates. Variables which had p value < 0.05 in multivariable analysis using the cox proportional hazard model were declared as statistically significant predictors of mortality. …”
Get full text

Analiza troškova kvalitete odabranih građevinskih radova by Ksenija Tijanić, Diana Car-Pušić, Zlata Dolaček-Alduk

“…Pored toga, kad se radnoj operaciji pristupa s potrebnom pozornošću, smanjuje se i mogućnost pogreške, potreban dodatni rad, a time i dodatni troškovi za kvalitetu.…”
Get full text

Cell Wall Protein 2 as a Vaccine Candidate Protects Mice Against <i>Clostridioides difficile</i> Infection by Shaohui Wang, Joshua Heuler, Jessica Bullock, Junling Qin, Soumyadeep Chakraborty, Agbendeh Lubem Nathaniel, Shifeng Wang, Xingmin Sun

“…Conclusions: Our report demonstrates for the first time the potential of Cwp2_A as an effective vaccine candidate against CDI in mice.…”
Get full text

The trajectory of changes in cognitive frailty and factors influencing it in elderly patients with cerebral infarction by Shengnan Xu, Qin Liang, Li Zhang, Shihua Liu

“…[Objective] The trajectory of cognitive frailty in elderly patients with cerebral infarction was analyzed, and the influencing factors were discussed. [ Methods] A total of 100 elderly patients with cerebral infarction hospitalized in Suzhou Hospital of Anhui Medical University from January to September in 2023 were selected for the study.Clinical data were collected on the patients, and cognitive frailty was assessed using the Frailty Screening Scale and the Montreal Cognitive Assessment Questionnaire (MoCA) at the time of admission and 1, 3, 6 months after treatment.Failty score ≥3 scores and MoCA <26 scores were defined as cognitive fraily.Potential categories of cognitive frailty change trajectories were identified by latent category growth modeling, and multifactorial logistic regression analyzed the factors influencing patients' cognitive frailty change trajectories. [ Results] The trajectory of cognitive frailty change in elderly patients with cerebral infarction identified by model fitting can be categorized into a group with a persistently low level of frailty (30 cases), a group with a slow rise in frailty (52 cases), and a group with a persistently high level of frailty (18 cases).Multifactorial logistic regression analysis showed that older age, poor sleep quality, and the number of comorbid chronic diseases > 4 were all risk factors for the development of persistent low levels of cognitive frailty into a slow rise in cognitive decline in elderly patients with cerebral infarction (P<0.05), Higher body mass index and high self-care ability were both protective factors for the development of persistent low levels of cognitive decline into a slow rise in cognitive decline in elderly patients with cerebral infarction (P<0.05).Older age, poor sleep quality and the number of comorbid chronic diseases >4 were risk factors for the progression of persistent low levels of cognitive decline to persistent high levels of cognitive decline in elderly patients with cerebral infarction (P < 0.05), and higher self-care ability were protective factors for the progression of persistent low levels of cognitive decline to persistent high levels of cognitive decline in elderly patients with cerebral infarction (P < 0.05). …”
Get full text

A comparative study on the efficacy of over-the-counter wax solvents versus distilled water for managing ear cerumen by Syed. Mohd. Ahmad, Rajesh Kumar Suman, Simran Kaur Pal, Ayush Agrawal

“…Furthermore, five subjects in group A developed otitis externa, compared with three in group B. The average time required for ear suctioning to visualize the tympanic membrane was 9.24 ± 2.50 min in group A and 9.68 ± 2.18 min in group B. …”
Get full text

Allograft tolerance after adult living donor liver transplantation: a case-control study by Mohamed S. Habl, Moataz Maher Emara, Reham A. Zayed, Ahmed M. Sultan, Ahmed Elsabagh, Ahmed Marwan Elsaid, Ehab E. Abdel-khalek, Mohamed M. El-Saadany, Mohamed Abdel Wahab, Ahmed Shehta

“…Age was significantly higher in Group 1. The median time for tolerance among the study recipients was 60 months (36–168). …”
Get full text

Wetland elevation change following beneficial use of dredged material nourishment by Brian D. Harris, Aleksandra Ostojic, Lenore P. Tedesco, Keith VanDerSys, Susan Bailey, Justin L. Shawler, Navid H. Jafari, Monica Chasten

“…Multispectral surveys were performed to document the revegetation of the nourished island over time.ResultsThe placement of dredged material smothered the vegetation, but the site experienced significant revegetation (low of 22% cover in August 2021 to 52% in September 2023) after three full growing cycles. …”
Get full text