Effects of Whey Protein Concentrate on the Bioaccessibility and Microstructure of 5-Methyltetrahydrocalcium Folate in Simulated Digestive Environment in Vitro by Yusong ZHANG, Weiran CUI, Zhenyue TANG, Hongyu BAI, Meili SHAO

“…At an intestinal pH of 7 and a digestion time of 5 hours, the WPC-5-MTHF group displayed the best bioaccessibility, which was twice as high as that of the 5-MTHF group, at 45.17% and 42.32%, respectively. …”
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Survival and risk factors for metastatic colorectal cancer patients with a history of prior malignancy by Yiwen Qiu, Nida Cao, Dan Meng, Jian Yuan, Yingjie Zhu

“…The objective is to facilitate timely and proactive treatment for patients following the disclosure of results, thereby instilling confidence in the management of mCRC.…”
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Non-invasive imaging with ICOS-targeting monoclonal antibody for preclinical diagnosis of rheumatoid arthritis in a humanized mouse model by Shao Duan, Chao Li, Feng Yan, Yifei Xia, Shuaiming Shao, Weiyu Chen, Zunyu Xiao, Gongping Xu

“…The receiver operating characteristic (ROC) curve created based on NIRF imaging quantification could distinguish the huPBMC-AIA group from the control group at all time points imaged. Conclusion In this study, we first developed an optical imaging probe targeting human ICOS, Cy7-ICOS mAb. …”
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Vitamin K Antagonist Use and Level of Anticoagulation Control Among Patients at a Tertiary Hospital in Northern Tanzania by Sarah K. Gharib MMed, Abid M. Sadiq MMed, Faryal M. Raza MMed, Sophia S. Muhali MMed, Annette A. Marandu MMed, Norman J. Kyala MMed, Eliasa K. Ndale MMed, Venance P. Maro MMed, William P. Howlett PhD, Elifuraha W. Mkwizu MMed, Nyasatu G. Chamba PhD, Furaha S. Lyamuya MMed, Elichilia R. Shao MMed, Kajiru G. Kilonzo MPhil

“…The level of anticoagulation control was determined through the calculation of the time-in-therapeutic range (TiTR) using the Rosendaal and the percent of INR in therapeutic range methods. …”
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Trajectories of self-rated health in an older general population and their determinants: the Lifelines Cohort Study by Barbara C van Munster, Nynke Smidt, Sophia E de Rooij, Marlies Feenstra, Janet L MacNeil Vroomen

“…Being women (OR: 1.4; 95% CI: 1.0 to 1.9), low education (OR: 2.1; 95% CI: 1.5 to 3.0), one (OR: 10.4; 95% CI: 7.4 to 14.7) or multiple chronic diseases (OR: 37.8; 95% CI: 22.4 to 71.8), smoking (OR: 1.8; 95% CI: 1.0 to 3.2), physical inactivity (OR: 3.1; 95% CI: 1.8 to 5.2), alcohol abstinence (OR: 2.2; 95% CI: 1.4 to 3.2) and deviating physiological markers (OR: 1.5; 95% CI: 1.1 to 2.0) increase the odds for a higher probability of poor SRH trajectory membership compared with excellent SRH trajectory membership.Conclusion SRH of community-dwelling older adults is stable over time with the majority (65%) having moderate SRH. …”
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Assessment of genetic polymorphism in sea buckthorn (Hippophae L.) of different environmentally-geographical origin by ISSR-markers by A. Y. Zemtsova, Y. A. Zubarev, A. V. Gunin, M. S. Ivanova

“…Some efforts of foreign scientists in this field are concerned with only big systematic groups like species and subspecies. At the same time genetic researches inside of subspecies mongolica growing in Siberia till recently have not been started. …”
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Fatigue after subarachnoid haemorrhage: a study of patients with good clinical outcome by G. Makarevičius, K. Pilypaitė, G. Terbetas, G. Šustickas, G. Bulotienė

“…This is most evident in those patients who had poorer clinical condition on admission and worsened over time. General and physical fatigue were the most pronounced types of fatigue in our study group. …”
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Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers by Caio Ambrosio Leal-Dutra, Lok Man Yuen, Bruno Augusto Maciel Guedes, Marta Contreras-Serrano, Pedro Elias Marques, Jonathan Zvi Shik

“…While autophagy is a ubiquitous and often highly derived process across the tree of life, our study reveals a new role for autophagy as a mechanism of functional integration between ant farmers and their fungal crop, and potentially as a signifier of higher-level homeostasis between uniquely life-time committed ectosymbionts.…”
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Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice by Chu X, Ge Y, Geng C, Cao P, Wei P, Fu B, Deng Z, Li Y, Zhao G

“…The neuronal damage, microglial activation, inflammatory responses, and functional changes were determined by TUNEL assays, immunohistochemistry, quantitative real-time polymerase chain reaction and behavioral tests. …”
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Initial Development of the Activity Card Sort-Advancing Inclusive Participation from a Homeless Population Perspective by Quinn P. Tyminski, Ronald R. Drummond, Claire F. Heisey, Shelby K. Evans, Audra Hendrix, Lisa A. Jaegers, Carolyn M. Baum

“…Participants experiencing homelessness (phase 1: N=13, phase 2: N=10) were required to be seeking services at the homeless shelter, while nonhomeless participants (phase 2: N=30) worked full-time, resided with a significant other, and had personal transportation. …”
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Physical, Microbial, and Chemical Quality of Hot-Air-Dried Persimmon (Diospyros kaki) Chips during Storage by Rebecca R. Milczarek, Ana M. Vilches, Carl W. Olsen, Andrew P. Breksa, Bruce E. Mackey, Maria T. Brandl

“…For both preparations, the contents of ascorbic acid and carotenoids experienced time-dependent decreases. Plastic zip-top bags and Met-PET bags with desiccant packets performed equally well as packaging for most of the quality metrics tracked during this study. …”
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Effect of Traditional Chinese Medicine on Inflammatory Mediators in Pediatric Asthma by Hui Du, Yonghong Wang, Yumin Shi, Jian Yu, Wen Sun, Yiqun Zhang

“…There were 35 patients in TCM group and 34 patients in SM group providing venous blood. Real-time PCR was used to determine the mRNA expression levels of interleukin- (IL-) 10, IL-17, matrix metalloproteinase-9 (MMP-9), and transforming growth factor β1 (TGF-β1) in peripheral blood mononuclear cells before and after treatment. …”
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The impact of teaching approach on horse and rider biomechanics during riding lessons by Anna Byström, Agneta Egenvall, Marie Eisersiö, Maria Terese Engell, Sigrid Lykken, Susanne Lundesjö Kvart

“…S2 and N2 focused relatively more on the walk, asking the riders to count each walk stride or focus on the rhythm. With S2, the timing between up-down movements of the withers and croup in walk was closest to the ideal 25 % (16–17 % vs. 8–14 % for the others, p < 0.05). …”
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Budesonide in treatment of alcohol-induced severe hepatitis: results of randomized trial by I. I. Komkova, M. V. Mayevskaya, V. T. Ivashkin

“…Hepatorenal syndrome was significantly more frequent in the second group (р=0,033).Conclusions. Short-time survival in budesonide and prednisolone group does not differ significantly. …”
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Application of a novel sliding ⁃ traction head holder in craniovertebral junction abnormalities surgery by WU Kun, ZHANG Fan, FAN Tao

“…All patients underwent posterior facet distraction and fusion (PFDF) under traction of the novel sliding‐traction head holder. The operation time, intraoperative blood loss, and postoperative complications were recorded. …”
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Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain by Gui-Lin Jin, Sai-Di He, Shao-Mei Lin, Li-Mian Hong, Wan-Qing Chen, Ying Xu, Jian Yang, Su-Ping Li, Chang-Xi Yu

“…Western blot analysis and quantitative real-time polymerase chain reaction (qPCR) were used to examine the modulator effect of koumine on microglial M1 polarization. …”
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A qualitative study to understand the facilitators of and barriers to retention in care to the national PMTCT Option B+ programme in Uganda. by Charity Kyomugisha-Nuwagaba, Rachel King, Rose Baryamutuma, Simon Muhumuza, Linda N Kisakye, William Bazeyo, Evelyn Akello

“…Barriers included self-stigma and fear of disclosure, mental health challenges, community perceptions, poor health provider attitudes and structural challenges, lack of transportation and food, long waiting time at health facilities and client mobility. Both the clients retained and not retained in care discussed mental illness, feeling sick and competing priorities as barriers. …”
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Ketosis Onset Type 2 Diabetes Had Better Islet β-Cell Function and More Serious Insulin Resistance by Hongyun Lu, Fang Hu, Yingjuan Zeng, Lingling Zou, Shunkui Luo, Ying Sun, Hong Liu, Liao Sun

“…Diabetic ketosis had been identified as a characteristic of type 1 diabetes mellitus (T1DM), but now emerging evidence has identified that they were diagnosed as T2DM after long time follow up. This case control study was aimed at comparing the clinical characteristic, β-cell function, and insulin resistance of ketosis and nonketotic onset T2DM and providing evidence for treatment selection. 140 cases of newly diagnosed T2DM patients were divided into ketosis (62 cases) and nonketotic onset group (78 cases). …”
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Macrophage phenotype after human refluxate exposure, esophageal dysmotility and their correlation with gastroesophageal reflux disease by A. V. Paraskevova, A. S. Trukhmanov, O. A. Storonova, S. V. Lyamina, S. V. Kalish, S. S. Pirogov, A. B. Ponomarev, D. E. Rumyantseva, I. Yu. Malyshev, I. V. Maev, V. T. Ivashkin

“…The analysis of reflux characteristics showed that the total reflux time with pH &lt; 4 for BE patients was longer than that for NERD and EE patients. …”
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Detection of Masses in Mammogram Images Based on the Enhanced RetinaNet Network With INbreast Dataset by Wang M, Liu R, Luttrell IV J, Zhang C, Xie J

“…However, this process usually depends on the experience of radiologists and is always very time consuming.Patients and Methods: We propose to introduce deep learning technology into the process for the facilitation of computer-aided diagnosis (CAD), and address the challenges of class imbalance, enhance the detection of small masses and multiple targets, and reduce false positives and negatives in mammogram analysis. …”
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