Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

“…We found that the proportion of peripheral blood NK cells which expressed the activating receptors NKp30, NKp46, NKG2D, and DNAM-1 was significantly decreased in GC patients compared to healthy donors, and that this decrease was positively associated with tumor progression. At the same time, plasma TGF-β1 concentrations were significantly increased in GC patients and negatively correlated with the proportion of NKp30, NKp46, NKG2D, and DNAM-1 expressing NK cells. …”
Get full text

Regional hyperthermia for soft tissue sarcoma – a survey on current practice, controversies and consensus among 12 European centers by Siyer Roohani, Felix Ehret, Marcus Beck, Danai P. Veltsista, Jacek Nadobny, Sebastian Zschaeck, Sultan Abdel-Rahman, Franziska Eckert, Anne Flörcken, Rolf D. Issels, Stephan Klöck, Robert Krempien, Lars H. Lindner, Markus Notter, Oliver J. Ott, Daniel Pink, Vlatko Potkrajcic, Peter Reichardt, Oliver Riesterer, Mateusz Jacek Spałek, Emanuel Stutz, Rüdiger Wessalowski, Thomas Zilli, Daniel Zips, Pirus Ghadjar, David Kaul

“…Many clinical controversies exist that require a standardized consensus guideline and innovative study ideas. At the same time, our data has shown that existing guidelines and decades of experience with the technique of RHT have mostly standardized procedural aspects.Conclusions The provided results may serve as a basis for future guidelines and inform future clinical trials for RHT in STS patients.…”
Get full text

Assessment of Flood Mitigation Strategies: A Case Study of the Aït Athmane Center in the Errachidia Region by Kadiri Abdelhakim, Essafraoui Badre, Messaoudi Badre, Aït Lahssaine Ismail, Ait Said Brahim, El Ouali Mohamed, Kabiri Lahcen

“…The findings indicate that, for varying return periods, flows range from 60.13 m³/s to 92.69 m³/s, with a concentration-time of 125.55 minutes. The hydraulic study indicates an overflow risk, endangering nearby residents and their crops. …”
Get full text

Visible light photocatalytic degradation of tetracycline using copper ferrite nanoparticles synthesized via Glycine-Assisted combustion method by A. Dinesh, K. Radhakrishnan, V. Renuga, Rajendra P. Patil, Suriyaprakash Rajadesingu, S. Suthakaran, L. Guganathan, Manikandan Ayyar, Madhappan Santhamoorthy, Lalitha Gnanasekaran, Munawar Iqbal

“…The photocatalytic degradation of TC was studied using visible light and the effect of parameters such as the concentration of the catalyst (0.5 g/L to 2.5 g/L), initial TC concentration (10– 50 mg/L) and irradiation time (30–150 min). The degradation efficiency reached a maximum value of 95.8 % for a 150 min irradiation under the optimum condition of the photocatalytic activity was further raised by 25 % by the addition of hydrogen peroxide (H2O2). …”
Get full text

Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses by Mathias K.-M. Herzog, Audrey Peters, Nizar Shayya, Monica Cazzaniga, Kardokh Kaka Bra, Trisha Arora, Manja Barthel, Ersin Gül, Luca Maurer, Patrick Kiefer, Philipp Christen, Katharina Endhardt, Julia A. Vorholt, Gad Frankel, Markus M. Heimesaat, Stefan Bereswill, Cormac G. M. Gahan, Marcus J. Claesson, Xavier Domingo-Almenara, Wolf-Dietrich Hardt

“…Notably, we reveal for the first time that C. jejuni stably colonizes OligoMM12 mice, triggering inflammation. …”
Get full text

Effect of bisphosphonate on bone microstructure, mechanical strength in osteoporotic rats by ovariectomy by Yuzhu Wang, Zhanglin Wu, Chun Li, Chenhao Ma, Jingyang Chen, Mincong Wang, Dawei Gao, Yufeng Wu, Haibin Wang

“…Conclusion In a short time, the effects of BP intervention and osteoporosis on cortical bone were not obvious. …”
Get full text

Palliative care practice of a patient with envolizumab-induced exfoliative dermatitis complicated with schizophrenia (1例免疫治疗致剥脱性皮炎合并精神分裂症患者的安宁疗护实践)... by ZHANG Lufen (张芦芬), MENG Weifen (孟卫芬), LIU Wei (刘伟), YUE Jingyan (岳静燕)

“…The palliative care practice mainly included controlling the symptoms of exfoliative-induced dermatitis to improve comfort, finding psychological problems and mental disorders and then giving timely intervention, improving the strength of social support, paying attention to patients' spiritual needs and providing spiritual comfort, etc. …”
Get full text

Striking a balance between aesthetics and safety: a comparative study on the maternal and neonatal outcomes of mini-incision cesarean section by ChunLan Yuan, ShiMei He, WenQian Jian, MeiRong He, HuiFang Huang, JianChun Huang, MeiPing He, KaiSun Zhao

“…The study evaluated several variables, including the time from incision to fetal delivery (I-D), surgery duration, intraoperative blood loss, duration of postoperative antibiotic administration, post-operative hospitalization duration, incidence of wound infection, neonatal adverse outcomes, and blood routine parameters. …”
Get full text

Evaluation of Active Intraoperative Nerve Monitoring in Severe Developmental Dysplasia of the Hip Patients Undergoing Total Hip Arthroplasty by Alireza Manafi Rasi, MD, Sina Afzal, Dr., MD, Mojtaba Baroutkoub, MD, Hasan Shakiba, MD, Pooya Kalani, MD, Mehdi Tavassoli, MD, Reza Zarei, MD

“…This method allows for real-time assessment of nerve function throughout the surgical procedure, demonstrating its potential to minimize postoperative complications.…”
Get full text

Optimizing corrosion resistance of the Mg–4Zn-0.5Y-0.5Nd alloy by regulation of secondary phase and grain structure by C.C. Zhao, W.T. Ouyang, M. Wen, C. Yang, D.K. Xu, Y.F. Zheng, T.F. Xi, L.Y. Sheng

“…The Mg–Zn–Y-Nd alloys with different states all experience passivation, pitting corrosion, galvanic corrosion, localized corrosion, and extensive corrosion stages, but the duration time of different stages of different alloys differs obviously, which is mainly determined by the secondary phase morphology. …”
Get full text

The CuePed Trial: How Does Environmental Complexity Impact Cue Effectiveness? A Comparison of Tonic and Phasic Visual Cueing in Simple and Complex Environments in a Parkinson’s Dis... by Rodney Marsh, Michael H. Cole, Nadeeka N. W. Dissanayaka, Tiffany R. Au, Sandra Clewett, John D. O’Sullivan, Peter A. Silburn

“…In contrast, there was a nonsignificant trend toward improvement in FoG frequency, duration, and course time when the device was switched from off to tonic and to phasic modes for the obstacle course. …”
Get full text

Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1β, and Tumor Necrosis Factor-α via a NF-κB-Dependent Mechanism in HaCaT Keratinocytes by Bing-rong Zhou, Jia-an Zhang, Qian Zhang, Felicia Permatasari, Yang Xu, Di Wu, Zhi-qiang Yin, Dan Luo

“…These data demonstrate for the first time that palmitic acid can stimulate IL-6, TNF-α, IL-1β productions in HaCaT keratinocytes and cell proliferation, thereby potentially contributing to acne inflammation and pilosebaceous duct hyperkeratinization.…”
Get full text

A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression by Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

“…Studies in vitro demonstrated that si-Fe-HPP exhibited excellent biocompatibility, anti-inflammatory effects and prolonged stable retention time in knee joint. Intra-articular injection of si-Fe-HPP significantly attenuated cartilage degradation in mice with destabilization of the medial meniscus (DMM)-induced OA. …”
Get full text

Screen Guided Training Does Not Capture Goal-Oriented Behaviors: Learning Myoelectric Control Mappings From Scratch Using Context Informed Incremental Learning by Evan Campbell, Ethan Eddy, Xavier Isabel, Scott Bateman, Benoit Gosselin, Ulysse Cote-Allard, Erik Scheme

“…These findings demonstrate that CIIL can surpass traditional SGT methods in online performance and emphasize the value of real-time user-in-the-loop data for developing adaptable and intuitive myoelectric interfaces, with implications for prosthetics, rehabilitation, and telerobotics.…”
Get full text

Glutathione reductase plays a role in the metabolism of methylmercury degradation in Rhodotorula mucilaginosa by Yi Guo, Wenlong Deng, Qigui Mo, You Yu, Zhenwang Zhang, Mingjie Wei, Ruiling Tang, Surui Lu, Yanting Su

“…Its minimal inhibitory concentration and minimum lethal concentration reached 3 and 6 mg/L, respectively. At the same time, Rm4 can also degrade methylmercury. Unlike the traditional microbial methylmercury degradation pathways, R. mucilaginosa’s genome does not encode the organomercury lyase gene MerB. …”
Get full text

Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen by Aryeh Solomon, Noa Bossel Ben-Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai G Netea, Roi Avraham

“…The temporal dynamics of TI were further elucidated, revealing both early and delayed myeloid subsets with time-dependent, cell-type-specific STAT1 signatures. …”
Get full text

The Society of Orthodox Parishes of Petrograd and its Province (1920–1922): the Experience of Sobornost under Persecution by Goltsov, Nikita V.

“…The author also focuses on the peculiarities of the Society’s legal status and its actual position within the contexts of life within the church and under Soviet legislation in the early 1920s. Here, for the first time, the question of the organization’s relationship with the Petrograd Diocesan Council is posed, and analysis leads us to conclude that there was a conflict between the agencies of diocesan administration and the social movement within the church, which was clearly manifest in the late 1910s and early 1920s. …”
Get full text

Liquid-based cytological diagnosis of pancreatic neuroendocrine tumors using hyperspectral imaging and deep learning by Taojing Ran, Wei Huang, Xianzheng Qin, Xingran Xie, Yingjiao Deng, Yundi Pan, Yao Zhang, Ling Zhang, Lili Gao, Minmin Zhang, Dong Wang, Yan Wang, Qingli Li, Chunhua Zhou, Duowu Zou

“…For cell classification, the CNN system identified hyperspectral images containing PanNETs and benign cells with areas under the curve (AUCs) of 0.9981 and 0.9815 in datasets from two different time points, respectively, showing superior performance compared to the conventional RGB group, with corresponding AUCs of 0.9716 and 0.9550. …”
Get full text

Association Between Maternal Physical Activity From Pre-pregnancy to Child-rearing and Their Children’s Physical Activity in Early Childhood Among Japanese by Aya Yamada, Haruki Momma, Nozomi Tatsuta, Kunihiko Nakai, Takahiro Arima, Chiharu Ota, Nobuo Yaegashi, Ryoichi Nagatomi

“…Cumulative physical activity level in mothers was computed based on the categories (low, moderate, and high) of physical activity from five time points (pre-pregnancy, during pregnancy, 1.5, 3.5, and 5.5 years postpartum). …”
Get full text

Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications by Farhang Hameed Awlqadr, Ammar B. Altemimi, Qausar Hamed AlKaisy, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Tablo Azad H.Slih, Rawaa H. Tlay, Tarek Gamal Mohamed Abd El-Maksoud, Franscesco Cacciola

“…Smart packaging systems equipped with nanomaterials provide real-time contamination alerts and extend shelf life by enhancing barrier and antimicrobial properties. …”
Get full text