Epidemiological profile trends and cost of pediatric sickle cell disease in Brazil from 2008 to 2022 by Luiza Telles, Paulo Henrique Moreira Melo, Luana Baptistele Dornelas, Gabriele Eckerdt Lech, Natália Zaneti Sampaio, Ayla Gerk, Madeleine Carroll, Cristina Pires Camargo

“…Descriptive and inferential analyses, including time series and ARIMA regression, were employed. …”
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Biosynthesized ZnO and MnO nanoparticles from Aegle marmelos peel extract for alkylphenol removal in wastewater by Pouya Karami, Mazeyar Parvinzadeh Gashti, Narges Fereydouni, Alessandro F Martins

“…The alkylphenol removal efficiency was tested under varying conditions such as time, concentration, nanoparticle dose, pH, and temperature. …”
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Thermodynamic properties of iron, aluminum, boron and phosphorus in dilute silicon solutions by molecular interaction volume model by Li S.-Y., Liu K., Yang F., Xi F.-S., Wu J.-J., Ma W.-H., Lei Y., Wang Y.-J., Zhang X.-N.

“…The self-interaction parameters (εi,i) for Si-i system were obtained as εB,B= -2.728-362.031/T, εAl,Al = 2.157-1876.776/T, εFe,Fe= -4.842+14445.926/T and εP,P = -2.543+13767.036/T. At the same time, the interaction parameters among components B, Al, and Fe in dilute ternary Sii- j solutions were also derived as εFe,B=-1.2758-2946.306/T, εAl,B = 0.7467-9765.9298/T and εFe,Al= -1.39677+3319.6803/T. …”
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Lymphocyte Oxidative Stress/Genotoxic Effects Are Related to Serum IgG and IgA Levels in Coke Oven Workers by Meili Gao, Yongfei Li, Aqun Zheng, Xiaochang Xue, Lan Chen, Yu Kong

“…Significant differences were observed in biomarkers, including 1-hydroxypyrene levels, employment time, percentages of alcohol drinkers, MDA, 8-OHdG levels, CTL levels and CTM, MN, CA frequency, and IgG, IgA levels between the control and exposed groups. …”
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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

“…In this study, we employed the NanoString nCounter technology, an advanced multiplexed digital counting method of RNA molecules, to comprehensively characterize differentially expressed transcripts involved in metabolic pathways at distinct time points in osteogenically differentiating ASCs treated with or without the pan-DNMT inhibitor RG108. …”
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Intersigmoid Hernia: A Forgotten Diagnosis—A Systematic Review of the Literature over Anatomical, Diagnostic, Surgical, and Medicolegal Aspects by Stella Chiarini, Paolo Ruscelli, Roberto Cirocchi, Vito D’Andrea, Beatrice Sensi, Alberto Santoro, Alessia Corsi, Federico Zepponi, Piergiorgio Fedeli, Sara Gioia

“…The diameter of the sigmoid recess was greater in patients who underwent resection due to strangulation (mean 3.31 cm, SD 1.53 cm) compared to those who underwent only reduction of the hernia (mean 2.35 cm, SD 0.74 cm). The time from onset to operation was less in patients undergoing resection surgery due to throttling (mean 3.03 days, SD 3.01 days) compared to those who underwent only a reduction of hernia incarceration (mean 8.49 days, SD 6.83 days). …”
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A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei by Mitsuru Nakase, Jeewan Thapa, Vanaabaatar Batbaatar, Ochirbat Khurtsbaatar, Batchuluun Enkhtuul, Jugderkhorloo Unenbat, Baasansuren Lkham, Sachiho Fujita, Ai Koshikawa, Apichai Tuanyok, Vannarat Saechan, Hideaki Higashi, Kyoko Hayashida, Yasuhiko Suzuki, Chie Nakajima, Takashi Kimura

“…This method was used to test for the presence of B. mallei DNA in swabs collected from the nasal cavity and ulcerated skin of 19 B. mallei-infected horses and five uninfected horses and was compared with the real-time PCR method. These two tests showed 87.5% agreement for the positive samples and 100% agreement for the negative samples. …”
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Deep Learning for Identification and Characterization of Ca ii Absorption Lines: A Multitask Convolutional Neural Network Approach by Yang Liu, Jie Li, Linqing Gao, Haotong Zhang, Zhenghua Xu, Yu Wang, Wenbin Lin

“…However, detecting these lines, particularly Ca ii absorption lines, is a time-consuming and laborious process. Existing deep learning methods are prone to false positives and still require extensive manual verification and parameter measurement. …”
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A backwater technology for enhancing pollutants discharge from aquaculture tanks in a Litopenaeus vannamei recirculating aquaculture system: Performance and control models by Jianping Xu, Yishuai Du, Jiawei Zhang, Fudi Chen, Li Zhou, Tianlong Qiu, Jianming Sun

“…Additionally, the relationship between the working time of the IEB device (TIEB) and the backwashing cycle of the Microscreen drum filter (TMDF) was studied, and a relevant model was established. …”
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Recommendations for developing, documenting, and distributing data products derived from NEON data by Jeff W. Atkins, Kelly S. Aho, Xuan Chen, Andrew J. Elmore, Rich Fiorella, Wenqi Luo, Danica Lombardozzi, Claire Lunch, Leah Manak, Luis X. dePablo, Allison N. Myers‐Pigg, Sydne Record, Tong Qiu, Samuel Reed, Benjamin Ruddell, Brandon Strange, Christa L. Torrens, Kelsey Yule, Andrew D. Richardson

“…Derived data products directly benefit the research community and increase the impact of NEON data by broadening the size and diversity of the user base, decreasing the time and effort needed for working with NEON data, providing primary research foci through the development via the derivation process, and helping users address multidisciplinary questions. …”
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Evaluation of Antibiotic Resistance and Biofilm Production among Clinical Strain Isolated from Medical Devices by Veronica Folliero, Gianluigi Franci, Federica Dell’Annunziata, Rosa Giugliano, Francesco Foglia, Rossella Sperlongano, Anna De Filippis, Emiliana Finamore, Massimiliano Galdiero

“…Identification of isolates and antibiotic susceptibility testing were performed using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and Phoenix Becton Dickinson, respectively. …”
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Compost from the food waste for organic production of cabbage, cauliflower, and radish under sub-tropical conditions by Neha Kumari, Anit Sharma, Mamta Devi, Atif Zargar, Sunny Kumar, Umesh Thakur, Ajay Bhatia, Khushboo Badhan, Sunaina Chandel, Arpana Devi, Kriti Sharma, Shweta Kumari, Mussarat Choudhary, Arup Giri

“…The yield increment in percentages of cabbage, cauliflower, and radish was infinite %, 220.08 %, and 278.49 %, respectively. The day in terms of time, compost, and their interaction has a significant effect on the better health of cabbage, cauliflower, and radish, and more yields achieved. …”
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Staging in the treatment of chronic calculous cholecystitis, complicated by choledocholithiasis by Alexander V. Smirnov, Vladimir R. Stankevich, Dmitry V. Sazonov, Artur R. Akhmedianov, Aishe A. Keshvedinova, Nikolay A. Solovyev, Yury V. Ivanov, Robert I. Khabazov

“…AIM: To define the optimal timings of performing the laparoscopic cholecystectomy after an endoscopic lithoextraction in cases of chronic calculous cholecystitis, complicated by choledocholithiasis. …”
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Solar Energetic Particle Events Detected in the Housekeeping Data of the European Space Agency's Spacecraft Flotilla in the Solar System by Beatriz Sánchez‐Cano, Olivier Witasse, Elise W. Knutsen, Dikshita Meggi, Shayla Viet, Mark Lester, Robert F. Wimmer‐Schweingruber, Marco Pinto, Richard Moissl, Johannes Benkhoff, Hermann Opgenoorth, Uli Auster, Jos deBrujine, Peter Collins, Guido DeMarchi, David Fischer, Yoshifumi Futaana, James Godfrey, Daniel Heyner, Mats Holmstrom, Andrew Johnstone, Simon Joyce, Daniel Lakey, Santa Martinez, David Milligan, Elsa Montagnon, Daniel Müller, Stefano A. Livi, Timo Prusti, Jim Raines, Ingo Richter, Daniel Schmid, Peter Schmitz, Håkan Svedhem, Matt G. G. T. Taylor, Elena Tremolizzo, Dimitri Titov, Colin Wilson, Simon Wood, Joe Zender

“…These counters typically have a sudden large increase in a short time in their error counts that generally match the arrival of energetic particles to the spacecraft. …”
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CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy by Ashley J. Schlafstein, Allison E. Withers, Soumon Rudra, Diana Danelia, Jeffrey M. Switchenko, Donna Mister, Saul Harari, Hui Zhang, Waaqo Daddacha, Shahrzad Ehdaivand, Xiaoxian Li, Mylin A. Torres, David S. Yu

“…In a Cox proportional hazards model, using a time-dependent covariate to evaluate the risk of death between groups beyond 3 years, high CDK9 expression was significantly associated with an increase in OS (HR: 0.26, 95% CI: 0.07-0.98, p=0.046). …”
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Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

“…Despite this notable progress, challenges remain, as not all patients respond favorably to ICIs, and resistance to therapy can develop over time. A crucial factor influencing clinical response to immunotherapy is the tumor microenvironment (TME). …”
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Re-analysis of the current status of clinical trial registration in China by Shuwen Li, Shuwen Li, Jianhao Li, Wenjing Zeng, Zhicheng Li, Jietong Zhang, Siying Wang, Nenggui Xu, Zeli Li, Zeli Li

“…NoteExpress software was used for screening, EXCEL for data organization and analysis, the Word Cloud website for constructing word frequency maps, and Origin software for visualization.ResultsAmong the 94 articles included, common analysis items included the number of registered projects, types of research, registration time, types of registration institutions, and regional distribution. …”
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Anti-Inflammatory and Antinociceptive Activities of Bufalin in Rodents by Lili Wen, Yang Huang, Xianbiao Xie, Wan Huang, Junqiang Yin, Wenqian Lin, Qiang Jia, Weian Zeng

“…Bufalin also reduced acetic acid-induced writhing and the licking time in the formalin test and increased hot-plate reaction latencies. …”
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Clarification of factors associated with post-artesunate delayed hemolysis (PADH): Analysis of 327 patients with severe imported Plasmodium falciparum malaria in France by Pierre-Louis Conan, Marc Thellier, Eric Kendjo, Sandrine Houzé, Rémonie Seng, Stéphane Jauréguiberry

“…Results: In the analyzed population (n = 327), 49 PADH events occurred after a median time of14 days (IQR, 13–17) after artesunate initiation. …”
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Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa) by E. Agbodjento, J. R. Klotoé, T. I. Sacramento, T. V. Dougnon, E. Déguenon, J. Agbankpé, K. Fabiyi, P. Assogba, M.-P. Hounkanrin, R. Akotegnon, T. J. Dougnon, J.-M. Atègbo

“…These data suggest that the use in traditional medicine of studied plants at high doses and repeated over a long period of time requires special attention.…”
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