Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma by Hai-Peng Wei, Song Zhan, Qing-An Zhu, Zhen-Juan Chen, Xian Feng, Jun-Yuan Chen, Qi-Lin Zhang, Jingjie Zhao, Lingzhang Meng

“…In order to validate the sRNA-seq data, expression of 15 randomly selected DEMs was measured using the TaqMan probe-based quantitative real-time PCR. Functional analysis of predicted target genes of DEMs in BCCs shows that these miRNAs are primarily involved in various types of cancers, immune response, epithelial growth, and morphogenesis, as well as energy production and metabolism, indicating that BCC development is caused, at least in part, by changes in miRNA regulation for biological and disease processes. …”
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The Relationship of Hematologic Parameters and Lipid Profile with Acute Ischemic Stroke by Sibel Canbaz Kabay, Fatma Akkoyun Arıkan, Dursun Ceylan, Merve Yatmazoğlu Çetin, Niyazi Uysal, Muhammed Alperen Bardakçı, Gönül Akdağ, Mustafa Çetiner, Emine Saygın Uysal

“…Laboratory data, demographic, and clinical characteristics were recorded at the time of admission. Neurological disabilities of the patients 3 months after treatment were evaluated with the modified Rankin Scale (mRS). mRS 0-2 was considered a good prognosis and mRS 3-6 was considered a poor prognosis. …”
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Determining the effect of frailty on survival in advanced ovarian cancer: study protocol for a prospective multicentre national cohort study (FOLERO) by Daniel Hunde, Niklas Ekerstad, Mihaela Asp, Päivi Kannisto, Madelene Wedin, Charlotte Palmqvist, Pernilla Dahm-Kähler, Yvonne Brandberg, Mirna Abraham-Nordling, Kristina Åhlund, Vilhelm Mörlin, Nina Groes-Kofoed, Sahar Salehi

“…The result of the study will have a direct impact on clinical management and patient-selection as the results are expected to have a high external validity. Total study-time is 5 years, with 3 years of accrual. All participating centres started accrual by September 2024. …”
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A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome by Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl

“…Existing methods to measure sterols in blood, particularly plant sterols, are often laborious and time consuming. Partly as a result, clinical access to sterol measurements is limited in many parts of the world. …”
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The role of FAM171A2-GRN-NF-κB pathway in TBBPA induced oxidative stress and inflammatory response in mouse-derived hippocampal neuronal HT22 cells by Yi Wang, Jing Shan, Ling Zhang, Rui Wang, Meng-Yu Wu, Hong-Mei Li, Hai-Ming Xu

“…Therefore, for the first time, our data indicate that TBBPA-induced oxidative stress and inflammatory response is closely related to the FAM171A2-GRN-NF-κB pathway.…”
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Comparing acute versus AIDS ART initiation on HIV-1 integration sites and clonal expansion by Jun Wang, Nan Xiao, Zhengnong Zhu, Haiyan Qiao, Fang Zhao, Lukun Zhang, Jizhou Gou, Mengji Lu, Yun He, Hongzhou Lu, Qian Li

“…Monoclonal UIS accumulation, predominantly in-gene regions, was influenced by ART timing and duration, with early treatment delaying this process. …”
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Gastrointestinal complaints in patients with anorexia nervosa in the timecourse of inpatient treatment by Caroline Riedlinger, Caroline Riedlinger, Nazar Mazurak, Nazar Mazurak, Norbert Schäffeler, Andreas Stengel, Andreas Stengel, Andreas Stengel, Katrin Elisabeth Giel, Katrin Elisabeth Giel, Stephan Zipfel, Stephan Zipfel, Paul Enck, Paul Enck, Isabelle Mack, Isabelle Mack

“…In addition to treatment time, the strongest predictors were ED pathology at admission for the development of abdominal pain, constipation, reflux, and total GI symptoms; stress for the development of constipation and total GI symptoms; and depression for constipation.ConclusionsInforming patients with AN about the course of GI symptoms and their improvement during weight rehabilitation may help support compliance during treatment.…”
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Neuron-inspired CsPbBr3/PDMS nanospheres for multi-dimensional sensing and interactive displays by Junhu Cai, Xiang Zhang, Yu Chen, Wenzong Lai, Yun Ye, Sheng Xu, Qun Yan, Tailiang Guo, Jiajun Luo, Enguo Chen

“…The regular pressure-sensitive property, discovered for the first time, is attributed to the regular morphology of the nanosphere, the inherent low rigidity of the PDMS shell, and the uniform distribution of the CsPbBr3 core material in combination. …”
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Impact of antibiotic prophylaxis on gut microbiota in colorectal surgery: insights from an Eastern European stewardship study by Irina Cezara Văcărean-Trandafir, Roxana-Maria Amărandi, Iuliu Cristian Ivanov, Loredana Mihaiela Dragoș, Mihaela Mențel, Ştefan Iacob, Ştefan Iacob, Ana-Maria Muşină, Ana-Maria Muşină, Elena-Roxana Bărgăoanu, Cristian Ene Roată, Cristian Ene Roată, Ștefan Morărașu, Ștefan Morărașu, Valeri Țuțuianu, Marcel Ciobanu, Mihail-Gabriel Dimofte, Mihail-Gabriel Dimofte

“…We analyzed fecal samples collected from patients before and 7 days post-antibiotic treatment, focusing on the V3–V4 region of the 16S rRNA gene.ResultsOur findings indicate that inconsistent antibiotic prophylaxis policies—varying in type, dosage, or therapy duration—significantly impacted the gut microbiota and led to more frequent dysbiosis compared to stricter prophylactic antibiotic practices (single dose, single product, limited time).DiscussionWe emphasize the need for standardized antibiotic prophylaxis protocols to minimize dysbiosis and its associated risks, promoting more effective antimicrobial use, particularly in low- and middle-income countries (LMICs).…”
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Activity of sorghum aphid and its natural enemies in the context of agroecological and weather conditions by Tomasz E. Koralewski, Tomasz E. Koralewski, Michael J. Brewer, Leonel L. Deleon, Norman C. Elliott, Kristopher Giles, Adrianna Szczepaniec, Ashleigh M. Faris, Ashleigh M. Faris

“…We built multiple regression models using data from the years 2017–2019 for metrics such as maximum number of insects per leaf, response time of natural enemies to pest presence, and speed of increase in insect abundance. …”
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Rapid literature mapping on the recent use of machine learning for wildlife imagery by Nakagawa, Shinichi, Lagisz, Malgorzata, Francis, Roxane, Tam, Jessica, Li, Xun, Elphinstone, Andrew, Jordan, Neil R., O'Brien, Justine K., Pitcher, Benjamin J., Van Sluys, Monique, Sowmya, Arcot, Kingsford, Richard T.

“…They dramatically speed up the time to detect, count, and classify animals and their behaviours. …”
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Spectrum and Location of Ongoing Extreme Particle Acceleration in Cassiopeia A by Jooyun Woo, Kaya Mori, Charles J. Hailey, Elizabeth Spira-Savett, Aya Bamba, Brian W. Grefenstette, Thomas B. Humensky, Reshmi Mukherjee, Samar Safi-Harb, Tea Temim, Naomi Tsuji

“…The Cas A observations and spectral modeling represent the first time radio, X-ray, gamma-ray, and CR spectra have been self-consistently tied to a specific acceleration mechanism—mNLDSA—in a young SNR.…”
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Integrative analysis of anoikis-related prognostic signature to evaluate the immune landscape and predict therapeutic response in stomach adenocarcinoma by Ziyi Zhou, Lanlan Yang, Yuan Fang, Rongzhong Xu, Xi Wang, Yuli Wang, Zhihong Fang

“…Nomograms were created based on risk characteristics in combination with clinical variants and the performance of the model was validated with time-dependent AUC, calibration curves, and decision curve analysis (DCA). …”
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Transcriptomics Analysis of Maize (<i>Zea mays</i> L.) in Response to the Infection by <i>Setosphaeria turcica</i> by Hui Jia, Pan Li, Bu Tao, Yuwei Liu, Zhihang Liu, Mengfang Zhu, He Zhou, Maocun Wang, Jingao Dong, Shouqin Gu, Xiaodong Gong

“…In this study, we employed transcriptomics technology to comprehensively analyze alterations in RNA expression profiles within maize leaves at critical time points (hours post-infestation, 24 hpi, and 72 hpi) during <i>S. turcica</i> infection. …”
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Bone Mineral Status in Children and Adolescents with Klinefelter Syndrome by Stefano Stagi, Mariarosaria Di Tommaso, Cristina Manoni, Perla Scalini, Francesco Chiarelli, Alberto Verrotti, Elisabetta Lapi, Sabrina Giglio, Laura Dosa, Maurizio de Martino

“…We also calculated the z-scores of the phalangeal amplitude-dependent speed of sound (AD-SoS) and the bone transmission time (BTT). Results. KS children and adolescents showed significantly reduced AD-SoS (p<0.005) and BTT (p<0.0005) z-scores compared to the controls. …”
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The Ukrainian war and the pandemic: the impact on public health and the need for new health digital tools and the next level of intelligence by M. Geanta, B. Cucos, A. Boata, A.C. Nuta, F.M. Nuta, V.V. Semenov

“…Complex adaptive system models, new tools, and the next level of health and digital intelligence are needed to provide timely and valuable insights. Combining lessons learned from the COVID-19 pandemic, the threat of war, and the need for continuous outbreaks surveillance, new public health and digital intelligence tools must be designed and implemented at regional, European, and global levels.…”
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Classifying Sunn Pest Damaged and Healthy Wheat Grains Across Different Species with YOLOV8 and Vision Transformers by Melike Çolak, Özgü Özkan, Ali Berkol, Nergis Pervan Akman, Murat Ardıç, Okan Sezer, Nazife Gözde Ayter Arpacıoğlu, Zekiye Budak Başçiftçi, Murat Olgun

“…This challenge can be tackled cost-effectively with emerging technology. Over time, the number of researchers focusing on this problem by using various machine learning algorithms and image processing techniques has increased. …”
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Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing by Abd Kakhar Umar, Patanachai K. Limpikirati, Bachtiar Rivai, Ilham Ardiansah, Sriwidodo Sriwidodo, Jittima Amie Luckanagul

“…Strategies like hypoxic conditioning, dual responsiveness, and pulse laser activation enhance controlled release, targeted delivery, and real-time diagnostic techniques like ultrasound imaging and X-ray computed tomography (X-ray CT). …”
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Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations by Guillem López de Egea, Aida González-Díaz, Randall J Olsen, Gérard Guédon, Dàmaris Berbel, Immaculada Grau, Jordi Càmara, Lucía Saiz-Escobedo, Sara Calvo-Silveria, Irene Cadenas-Jiménez, José María Marimón, Emilia Cercenado, Antonio Casabella, Sara Martí, M. Ángeles Domínguez, Nathalie Leblond-Bourget, James M Musser, Carmen Ardanuy

“…Macrolides, lincosamides, and tetracyclines exhibited the highest resistance rates (>27%) and changed over time, linked to multiple MGEs. The mouse model highlighted the virulence of the CC20-stG62647 lineage, but these results were discordant with clinical data. …”
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Massive subcutaneous filariosis by Filaria martis in beech marten (Martes foina) in Italy by Giovanni Sgroi, Ranju Ravindran Santhakumar Manoj, Ettore Napoli, Nicola D'Alessio, Maria Gabriella Lucibelli, Claudio de Martinis, Esterina De Carlo, Peyman Khademi, Alireza Sazmand, Vincenzo Veneziano

“…This study reported for the first time F. martis subcutaneous filariosis in southwestern Italy, previously outlined only in northern and southeastern areas, indicating the circulation of this poorly investigated filarioid. …”
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