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58401
Interactions of Self-Assembled <i>Bletilla Striata</i> Polysaccharide Nanoparticles with Bovine Serum Albumin and Biodistribution of Its Docetaxel-Loaded Nanoparticles
Published 2019-01-01“…Additionally, the area under the concentration–time curve (AUC<sub>0–∞</sub>) of DTX-loaded BSPs-SA nanoparticles was about 1.42-fold higher compared with Duopafei<sup>®</sup> in tumor-bearing mice. …”
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58402
Fire return intervals and recruitment affect population growth rate of canopy trees in tall open forest in humid savanna
Published 2024-12-01“…Minimum fire return intervals of 2–5 years were generally required for λ ≥1 that would allow populations to persist; these were shorter with stochastic year‐to‐year timing of fires and with higher recruitment rates. …”
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58403
CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence
Published 2025-01-01“…Immunohistochemical (IHC) staining was carried out using a CD34 polyclonal antibody to determine intratumoral MVD, and the relationship of CD34-MVD with the clinicopathological characteristics and survival time of LUAD patients was analyzed.ResultsCD34-MVD was associated with tumor size, lymph node metastasis, tumor recurrence, and patient survival status; patients with tumor size ≤3 cm (P = 0.015), negative for lymph node metastasis (P = 0.049), no tumor recurrence (P = 0.021), and survival (P = 0.042) had higher MVD. …”
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58404
Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients
Published 2025-02-01“…The dynamic impact of sleep quality on cognitive function is positively correlated, and over time, there is an association between the remission speed of depressive or anxiety symptoms and improving the speed of cognitive function in patients with MDD.Keywords: major depressive disorder, sleep disorder, cognitive function, dynamic tracking, correlation, Latent Growth Curve Model…”
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58405
Study on the Fingerprint Spectrum and the Spectrum-Effect Relationship of Analgesic and Anti-Inflammatory Effects of the Aqueous Extract from Dalbergia hancai Benth
Published 2023-01-01“…In this study, the high-performance liquid chromatography (HPLC) method had been employed to establish the fingerprint of 10 batches of aqueous extract of D. hancai originated from different parts of China. At the same time, similarity evaluation, cluster analysis, and principal component analysis (PCA) had also been conducted to evaluate the common peaks. …”
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58406
Experimental Study of the Influence of Moisture Content on the Mechanical Properties and Energy Storage Characteristics of Coal
Published 2021-01-01“…As the moisture content increases, the area of hysteretic loop and elastic energy index WET of each coal sample are reduced, and the impact energy index KE is negatively correlated with the moisture content, whereas dynamic failure time is positively correlated with the moisture content, but this variation trend is gradually mitigated with the continuous increase of moisture content. …”
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58407
The Role of Leadership, Religiousness and Work Environment in Supporting Employee Performance and How Motivation Affects The Relationship
Published 2025-01-01“…Conclusion: This study shows that leadership and religiosity have a substantial impact on employee performance. At the same time, the work environment has a negative effect. motivation can have a positive influence on the relationship, as well as the work environment on employee performance. …”
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58408
Outcomes for Dostarlimab and Real-World Treatments in Post-platinum Patients With Advanced/Recurrent Endometrial Cancer: The GARNET Trial Versus a US Electronic Health Record-Based...
Published 2023-09-01“…**Objectives:** The objective of this study was to compare overall survival (OS) and describe time to treatment discontinuation (TTD) for dostarlimab (GARNET Cohort A1 safety population) with an equivalent real-world external control arm receiving non-anti-programmed death (PD)-1/PD-ligand (L)1/2 treatments (constructed using data from a nationwide electronic health record–derived de-identified database and applied GARNET eligibility criteria). …”
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58409
Pepper as a phytogenic additive in finishing lambs diets
Published 2025-02-01“…However, there was an effect (P < 0.05) of time on the pH and N-NH3 value of the rumen. The inclusion of pepper in the diet of confined lambs negatively alters dry matter and NDF intake without impairing nutrient digestibility, nitrogen utilization, and other ruminal parameters.…”
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58410
Modelling climate change and aridity for climate impact studies in semi-arid regions: The case of Giba basin, northern Ethiopia
Published 2025-01-01“…Historical data (1961–2019) from seven meteorological stations and global grided data were used for future climate projections (2020–2100) under the three emission scenarios (RCPs 2.6, 4.5, and 8.5) for the three-time horizons (2040s, 2060s, and 2080s). Analysis of results showed that rainfall and temperature projection on a monthly and/or seasonal basis has more significance than on an annual basis for impact studies particularly, in areas where irrigation practices are common like in the Giba basin. …”
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58411
Biochemical analysis of miR-217 and miR-532 in patients with fibromyalgia
Published 2025-02-01“…The miR-217 and miR-532 serum expressions were detected using quantitative real-time PCR (qRT-PCR). According to our data, the fold changes of miR-217 and miR-532 in fibromyalgia patients were significantly lower than in controls, for miR-217 (median = 0.1359, IQR: 0.038–0.287, P < 0.001) and miR-532 [median = 0.2199, IQR: (0.114–0.421), P < 0.001]. …”
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58412
Risk factors for long-term severe tricuspid regurgitation following mitral valve replacement: a retrospective study
Published 2025-01-01“…Results Logistic regression analysis indicated that serum creatinine levels (OR = 1.023, P = 0.026), atrial fibrillation (OR = 2.780, P = 0.040), and a history of permanent pacemaker implantation (OR = 3.029, P = 0.039) were significantly associated with the development of severe TR over time. In contrast, concurrent intraoperative tricuspid valvuloplasty was associated with a reduced risk of TR (OR = 0.315, P = 0.002). …”
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58413
Using Machine Learning to Predict Progression in the Gastric Precancerous Process in a Population from a Developing Country Who Underwent a Gastroscopy for Dyspeptic Symptoms
Published 2019-01-01“…Morbidity and mortality from gastric cancer may be decreased by identification of those that are at high risk for progression in the gastric precancerous process so that they can be monitored over time for early detection and implementation of preventive strategies. …”
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58414
Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases
Published 2025-01-01“…Ki-67 staining, a scratch experiment, real-time PCR, and Western blotting were used to explore the effect of the Th17 cell supernatant on keloid fibroblasts.ResultsOur findings revealed the intricate cellular landscape of immune cells in fibrotic skin diseases. …”
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58415
Why we need a representative organization of academic PRM in Europe, and why we need it now
Published 2025-01-01“…By leveraging successful models like the Association of Academic Physiatrists in the United States, Europe can develop a robust and credible voice for academic PRM. This initiative is timely and necessary to capitalize on the current momentum and ensure the future of academic PRM in Europe. …”
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58416
Green Analytical Method for Simultaneous Determination of Glucosamine and Calcium in Dietary Supplements by Capillary Electrophoresis with Capacitively Coupled Contactless Conducti...
Published 2023-01-01“…The CE analysis was performed in fused silica capillaries (50 μm inner diameter, 40 cm total length, 30 cm effective length), and the analytical time was around 5 min. After optimization, the CE conditions for selective determination of glucosamine and Ca2+ were obtained, including a 10 mM tris (hydroxymethyl) aminomethane/acetic acid (Tris/Ace) buffer of pH 5.0 as the background electrolyte; separation voltage of 20 kV; and hydrodynamic injection (siphoning) at 25 cm height for 30 s. …”
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58417
Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics
Published 2025-02-01“…Additionally, enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, real-time quantitative polymerase chain reaction (qPCR), and Western blot were employed to detect the changes in the expression of intestinal inflammatory factors, tight junction proteins, bile acid metabolism-related genes and proteins. …”
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58418
The Impact on Emergency Department Utilization and Patient Flows after Integrating with a General Practitioner Cooperative: An Observational Study
Published 2013-01-01“…Segmented regression analysis was used to analyze after-hours changes over time. Results. 59.182 patients attended the ED before the start of the ECAP and 51.513 patients after, a decrease of 13%. …”
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58419
Information manipulation on TikTok and its relation to American users' beliefs about China
Published 2025-01-01“…Study III involved a survey administered to 1,214 Americans that assessed their time spent on social media platforms and their perceptions of China. …”
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58420
Customer Loyalty Based on Service Quality, Banking Image, and Fairness Mediating Role of Customer Satisfaction
Published 2024-09-01“…Conclusion: This study shows that service quality and banking image have a substantial impact on customer loyalty. At the same time, the concept of fairness has a substantial impact on customer loyalty. …”
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