Allele-specific PCR with fluorescently labeled probes: criteria for selecting primers for genotyping by V. A. Devyatkin, A. A. Shklyar, A. Zh. Fursova, Yu. V. Rumyantseva, O. S. Kozhevnikova

“…The method consists of real-time PCR with a pair of primers and two oligonucleotide probes that are complementary to a sequence near a given locus in such a way that one probe is complementary to the wild-type allele, and the other to a mutant one. …”
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HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007) by Raj Kalkeri, Junzhong Peng, Chunsheng Huang, Zhaohui Cai, Roger G. Ptak, Mark J. Suto

“…To determine the stage of HBV life cycle inhibited by SRI-32007, time of addition experiment was conducted in HepG2-NTCP cell-based HBV infectious assay. …”
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Investigating the Expression of c-Myc and BIRC5 in TRAIL and PBOX-15 treated Metastatic Prostate Cancer Cells by Corinne Kai Leng Chew, Hannah O'Toole, Daniela M Zisterer, Seema M. Nathwani, Jade K. Pollock

“…Results c-Myc and BIRC5 expression was detected in the LNCaP cell line following a 24-hour treatment time with each treatment. TRAIL increased expression of c-Myc and BIRC5. …”
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Comparing the efficacy of live vs. video instructional demonstrations in dental education: a systematic review and meta-analysis by Rawan N. AlKahtani, Banna M. Alnufaiy, Refal S. Albaijan, Sarah M. Alnafaiy, Farah M. Elfakhri, Suha M. Aljudaibi

“…Of these, 8 studies were included in the meta-analysis.Students’ feedback reveals distinct preferences, with video demonstrations being commended for repeatability and clarity, while live demonstrations were valued for real-time interaction and guidance. Meta-analysis revealed that video-based learning significantly enhanced educational outcomes across various measures, including knowledge acquisition and practical skills over live demonstrations. …”
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Phosphate binder in dialysis: a cross-sectional study of patients' adherence and pill burden by Brunelle Bruna Scavello Coelho Ferezin, Luiza Karla Ramos Pereira de Araújo, Carolina Marquez Lima, Hugo Abensur, Benedito Jorge Pereira, Maria Aparecida Dalboni, Rosa Maria Affonso Moyses, Rosilene Motta Elias

“…Results: Patients (N = 137) were young, mostly women, and on dialysis for a median time of 53 months. Sevelamer and calcium carbonate were prescribed as P binders to 70.8% and 10.2% of patients, respectively, with no difference across dialysis modalities (p = 0.839). …”
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The association between recent stressful life events and brain structure: a UK Biobank longitudinal MRI study by Cheryl R.Z. See, Annabel X. Tan, Lucia R. Valmaggia, Matthew J. Kempton

“…Results Individuals who had experienced recent SLEs exhibited a slower rate of hippocampal decrease over time compared to individuals who did not report any SLEs. …”
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Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer by Sangavi Eswaran, Samatha Bhat, Dinesh Upadhya, Roshan Mascarenhas, Shama Prasada Kabekkodu

“…DOC2B-SiHa and vector-SiHa EVs were co-incubated separately with recipient cell and subjected to various cellular and biochemical experiments. For the first time, we demonstrated that DOC2B localizes to EVs, and its transfer to EV may require intracellular calcium. …”
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Economic evaluation of tranexamic acid for the treatment of acute gastrointestinal bleeding: a cost-effectiveness analysis using data from the HALT-IT randomised controlled trial by Ian Roberts, Vipul Jairath, Alec Miners, Jack Williams, Haleema Shakur-Still, Nuha Bazeer

“…Objective To perform an economic evaluation of tranexamic acid (TXA) versus no-TXA, in addition to current clinical practice, for acute gastrointestinal bleeding, using the results of the HALT-IT trial (NCT01658124), a large randomised controlled trial which included 11 937 patients.Design A cost-effectiveness modelling analysis, performed over a lifetime time horizon.Setting The analysis was performed from a UK health service perspective.Participants The model includes adults with acute gastrointestinal bleeding.Outcomes measures The model reports costs in Great British pounds in 2021 and outcomes as life years (LYs) and quality-adjusted life years (QALYs). …”
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The impact of firm-level innovation on labor productivity and employment in selected African countries by Zerayehu Sime, Getaw Tadesse

“…The effect is initially diminishing for unskilled workers and non-production workers, but it gradually increases over time. In general, the finding challenges the assumption that innovation uniformly improves productivity, instead revealing a more complex dynamic where job creation comes at the cost of lower productivity in certain labor segments.…”
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Data Augmentation and Machine Learning algorithms for multi-class imbalanced morphometrics data of stingless bees by Daisy Salifu, Lorna Chepkemoi, Eric Ali Ibrahim, Kiatoko Nkoba, Henri E.Z. Tonnang

“…Random forest recursive feature elimination technique was used to assess variable importance, guiding future studies on key morphometric measurements to save time and cost while maintaining high classification performance. …”
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Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau by WANG Zhenliang, CHEN Manyu, ZHAO Jianlin, YUAN Ke, YANG Jie, ZHANG Chen

“…[Results] (1) A total of 107 landslides from 2017 to 2021 were identified, including the specific location and accelerated deformation time of landslides. (2) With the increase of rainfall days in the early period, the correlations between cumulative rainfall and landslide shape variables showed a trend of first increasing and then decreasing. …”
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Temporal associations between microclimate, adult Aedes mosquito indices, and dengue cases at the residence level in Malaysia: Implications for targeted interventions. by Nur Athen Mohd Hardy Abdullah, Nazri Che Dom, Biswajeet Pradhan, Siti Aekball Salleh, Rahmat Dapari

“…<h4>Aims</h4>This study aims to contribute to the existing knowledge by investigating the association and time lags (TLs) between daily microclimate (DM), mosquito indices (MIs), and dengue cases at the residence level.…”
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Phytoalexin deficient 4 is associated with the lesion mimic trait in watermelon clalm mutant (Citrullus lanatus) by Jiale Shi, Congji Yang, Yuanyuan Qin, Qingqing Liu, Shengqi Hua, Defeng Wu, Wei Dong

“…According to quantitative real-time PCR analysis, the expression level of ClCG04G001930 was significantly higher in the clalm mutant than in normal watermelon. …”
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Impacts of surface wear of attachments on maxillary canine distalization with clear aligners: a three-dimensional finite element study by Qiuying Li, Bowen Xu, Dongyu Fang, Kai Yang

“…Once optimized root control attachments have been in place for more than 4 months and maxillary canine distalization is still required, orthodontists should closely monitor the wear of these attachments. If necessary, timely restoration or rebonding of the attachments is recommended.…”
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Metabolics-Based Study on the Therapeutic Mechanism Behind the Effect of Shenhuang Plaster Applied to the Shenque Acupoint on Gastrointestinal Motility in POI Mice by Yanan Shi, Chenglei Wu, Ting Liu, Rongyun Wang, Bin Ding, Qiuhua Sun

“…In this study, it was found, for the first time, that applying SHP to the Shenque acupoint could effectively regulate the serum metabolites of phenylalanine, carnitine, and glutamate, and improve postoperative intestinal motile disturbance through association with the intestinal flora.…”
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Predictive Utility of the HALP and Modified HALP Score for the Assessment of Operative Complications in Patients Undergoing Laparoscopic Cholecystectomy for Acute Cholecystitis by Yasemin Keskin, Hakan Sevinç, Selçuk Mevlüt Hazinedaroğlu, Şevket Barış Morkavuk, Şiyar Ersöz

“…<b>Background and Objectives</b>: The aim of the present study was to calculate HALP and modified HALP scores for patients diagnosed with acute cholecystitis (AC) and to determine the predictive utility of these scores for surgical timing and morbidity in patients who underwent surgery for AC. …”
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Hop to It! The Relationship Between Hop Tests and The Anterior Cruciate Ligament – Return to Sport Index After Anterior Cruciate Ligament Reconstruction in NCAA Division 1 Collegia... by Michael Zarro, Madelyn Dickman, Timothy Hulett, Robert Rowland, Derrick Larkins, Jeffrey Taylor, Christa Nelson

“… # Hypothesis/Purpose The purpose of this study was to examine the relationship between ACL-RSI scores and limb symmetry index (LSI) for the single hop for distance (SHD), triple hop for distance (THD), crossover hop for distance (CHD), timed 6-meter hop (T6H), and single leg vertical hop (SLVH) in a cohort of National Collegiate Athletic Association (NCAA) Division 1 collegiate athletes after ACLR. …”
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Status of zoonotic disease research in refugees, asylum seekers and internally displaced people, globally: A scoping review of forty clinically important zoonotic pathogens. by Regina Oakley, Nadja Hedrich, Alexandra Walker, Habtamu Merha Dinkita, Rea Tschopp, Charles Abongomera, Daniel H Paris

“…Migration pathways of displaced populations increased over time towards a more complex web, involving migration in dual directions. …”
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Ultrasonic characteristics of inserted central catheter related fibroblastic sleeve by Zhifei Ben, Jue Wang, Jinyong Zhan, Kaiying Xu

“…Understanding these ultrasonic characteristics can provide a reliable basis for their early diagnosis and timely treatment.…”
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Sorption behavior of pomegranate polyphenols on surfactant-modified clays in aqueous solution by Houda Saad, Thouraya Turki, Mondher Srasra, Ezzeddine Srasra

“…We investigate here, for the first time, the adsorption of pomegranate peels polyphenols on organophilic clays. …”
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