Mapping existing research on flushing peripheral vascular catheters: a scoping review protocol by Liping Liu, Peter J Carr, Orlaith Hernon, Jiaxin Deng, Catriona Duggan, Leo R Quinlan, Zina Alfahl

“…A scoping review is needed to explore and synthesise this evidence systematically and to systematically map the existing research on PVC flushing by assessing the scope, methodologies and outcomes of existing studies.Methods and analysis The review will adhere to the Joanna Briggs Institute (JBI) methodology, using a three-phase search strategy as recommended by JBI and covering the full-time range available in each database. Systematic searches will be conducted across Embase, Web of Science, PubMed, Scopus, and CINAHL; clinical trial registries; and grey literature sources to identify potentially eligible studies published up to May 2024. …”
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Biogeographic Insights Into the Late Miocene Diversification of the Giant Deep‐Ocean Amphipod Eurythenes by Carolina E. González, Johanna N. J. Weston, Reinaldo Rivera, Marcelo Oliva, Rubén Escribano, Osvaldo Ulloa

“…These large‐bodied scavengers play key roles in benthic communities. We constructed a time‐calibrated phylogeny using two mitochondrial DNA genes by analyzing publicly available data on 14 species of Eurythenes across a global depth range from 839 to 8081 m. …”
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Motivations and perceptions for physical activity in women living with metastatic breast cancer: a qualitative interview study by Mark Liu, Sharon Kilbreath, Jasmine Yee, Jane Beith, Justin McNab, Elizabeth Dylke

“…Results Twenty-three women participated; median age was 60 years (IQR: 20) and median time since metastatic diagnosis was 3.3 years (IQR: 3.0). …”
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Interest in digital health tools for miscarriage support: A qualitative assessment of Canadian women facing early pregnancy loss by Breanna Flynn, Anjali Sergeant, Genevieve Tam, Megan Gomes, Roopan Gill

“…Conclusion: Miscarriage is an emotionally difficult experience for women and their loved ones, who often do not receive timely and compassionate care within the healthcare system. …”
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Do meteorological variables impact air quality differently across urbanization gradients? A case study of Kaohsiung, Taiwan, China by Bohan Wu, Shuang Zhao, Yuxiang Liu, Chunyan Zhang

“…Impulse response analysis revealed that temperature had a notable positive and negative correlation effect on AQI over lagged periods, while wind speed showed a negative correlation with AQI in suburban areas, gradually shifting to a positive correlation over time; (3) Variance decomposition indicated that temperature had the largest impact on AQI in urban areas, particularly with cumulative lag effects, while wind speed was the main variables influencing air quality in suburban areas. …”
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Analysis of clinical and pathological prognostic factors of survival in rectal adenocarcinoma treated with preoperative radiochemotherapy by Sarhan Sydney Saad, Nora Forones, Gaspar Lopes Filho, Jaques Waisberg, Elesiario Caetano Júnior, Ricardo Artigiani-Neto, Delcio Matos

“…Results: The mean follow-up time was 62 months. The pathological complete response rate was 18.6%. …”
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The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level by Sara Farahi, Sara Hosseini, Hossein Ghanbarian, Seyed Mahmoud Hashemi, Mohammad Salehi, Samaneh Hosseini

“…The expression level of pluripotent genes (oct4, nanog, sox2, klf4), HDACs (hdac1, hdac2, and hdac3), and immune-related genes (including Qa-1, Qa-2, H2kb, H2kd, H2db, H2db, CIITA, H2-IE-βb, H2-IE-βd) in iPSC and ESC lines were assessed by real-time PCR analysis. The presence of MHC molecules on the surface of pluripotent stem cells was also checked by flow cytometry technique. …”
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Widening access to isotretinoin in primary care: an evaluation of New Zealand national dispensing data for isotretinoin for acne, 2008–2023 by Bruce Arroll, Diarmuid Quinlan, Peter Moodie, Rachel Petronella Roskvist, Jason Arnold

“…This is the first study demonstrating that, given appropriate postgraduate education and support, the isotretinoin risk–benefit profile may be enhanced to safely deliver high-quality, timely, equitable patient access to isotretinoin in primary care.…”
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Deformation Failure and Support Test of Surrounding Rock in Deep Arched Roadway with Straight Wall by Shuqi Pan, Shuaitao Liu, Liming Cao, Jianqiang Guo, Chao Yuan

“…The results showed that after the deep roadway is excavated with preload and high stress, the surrounding rock deformation, failure, and instability of the roadway mainly experience 3 periods: the first period is the period of uniform deformation of the roadway surrounding rock, the second period is the development period of the roadway surrounding rock slab structure, and the third period is the period of instability of the roadway surrounding rock slab structure. Combined with the time period of deformation and failure of the surrounding rock of the roadway, the damage scope of the surrounding rock and the actual situation of the site engineering. …”
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Enhanced Expression of NR2B Subunits of NMDA Receptors in the Inherited Glaucomatous DBA/2J Mouse Retina by Ling-Dan Dong, Jie Chen, Fang Li, Feng Gao, Jihong Wu, Yanying Miao, Zhongfeng Wang

“…Moreover, expression of Cdk5, p35 and ratio of p-NR2AS1232/NR2A progressively increased with time in both strains, suggestive of activated Cdk5/p35 signaling pathway. …”
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The PainSMART project: Protocol for a research program on effectiveness, mechanisms of effect and patient-practitioner experiences of the PainSMART-strategy as an adjunct to usual... by Richard Thompson, Maria Fors, Ann-Sofi Kammerlind, Pia Tingström, Allan Abbott, Kajsa Johansson

“…<h4>Outcome</h4>The primary outcome is 1) between group mean change over time from baseline to 24 hours post initial physiotherapy consultation and baseline to 3 months regarding self-reported average pain intensity and pain self-efficacy. …”
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Differentiation of Rat Adipose-Derived Stem Cells into Parathyroid-Like Cells by Ping Zhang, Hao Zhang, Wenwu Dong, Zhihong Wang, Yuan Qin, Changhao Wu, Qi Dong

“…SHH and activin A stimulated parathyroid hormone secretion by the adipose-derived stem cells and significantly increased the expression of calcium-sensing receptor (CaSR), parathyroid hormone, and glial cells missing homolog 2 (GCM2) in the cells in a time- and concentration-dependent manner. Conclusion. …”
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The effect of physical cues on platelet storage lesion by Lihan Cheng, Lu Wang, Shichun Wang, Qi Liu, Ronghua Diao, Chunyan Yao

“…The analysis of morphology, metabolism index, and levels of activation markers are used to monitor the quality of stored platelets and definite the role of physical cues in PSL.Result: In this study, centrifugation, leukofiltration and agitation lead to different degrees of platelet activation, with the extension of storage time. At one hour after separation, PSL can be found through structural change, metabolic parameters, and activation markers of platelets. …”
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Understanding personality pathology in a clinical sample of youth: study protocol for the longitudinal research project ‘APOLO’ by Nagila Koster, Igor Lusin, Paul T van der Heijden, Odilia M Laceulle, Marcel A G van Aken

“…Furthermore, results will give directions for early detection and timely interventions. This study has been approved by the ethical review committee of the Utrecht University Faculty for Social and Behavioural Sciences (FETC17-092). …”
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Assessment of long-term changes in subvalvular aortic stenosis in patients following transcatheter aortic valve implantation by Vladlen V. Bazylev, Andrey B. Voevodin, Alexey S. Masyutin

“…RESULTS: The average age of patients was 72.4±5.5 years, more than half of the subjects were women. 60% of patients were diagnosed with coronary artery disease at the time of TAVI. Pre- and postoperative median IVS thicknesses were 17.7±2.2 and 14.4±3.2 mm, respectively. …”
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Effects of high-intensity intermittent cross-training on maximal oxygen uptake by Xin Liu, Katsunori Tsuji, Yuzhong Xu, Motoyuki Iemitsu, Izumi Tabata

“…Significant group ​× ​time interactions were observed for both the running and bicycling V˙O2max (p ​< ​0.001 each). …”
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A Comparison of Resting Scapular Posture and the Davies Closed Kinetic Chain Upper Extremity Stability Test by John D Heick, Jenna Haggerty, Robert C Manske

“…Faulty scapular position has been linked to decreased scapular stability and is thought to be a result of weak or unbalanced timing in the recruitment of scapulothoracic dynamic stabilizing muscles. …”
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Assessment of correlation of fatigue in patients of rheumatoid arthritis using bristol rheumatoid arthritis fatigue multidimensional questionnaire score with disease activity – An... by Harpreet Singh, Kusum Yadav, Ritu Sangwan

“…Conclusion: The results of the present study indicate that fatigue quantum is related to disease activity and should be evaluated at the time of diagnosis. BRAF-MDQ is a simple, yet effective patient reported outcome questionnaire which assessed the fatigue quantum. …”
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WeARTolerance: Evaluating the impact of an arts-based program to reduce mental health-related stigma in young people. by Ana Beato, Leonor Pereira da Costa, Ana Carvalho, Sara Albuquerque, Isabel Santos

“…Participants' age and past psychiatric issues were fixed factors with random intercepts, and mixed effects models were used to analyze the attitudinal outcomes across time. In the second phase of this validation, nine teenagers aged between 12 and 16 participated in two focus groups conducted three months after the program. …”
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Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer by Linsheng Xu, Linsheng Xu, Bingde Hu, Jingli He, Xin Fu, Na Liu

“…Experimental assays, including CCK8 and wound-healing, demonstrated that intratumor microbiome-derived butyrate enhances the proliferation and migration of HCT15 cells in a time- and concentration-dependent manner. Cell survival analysis further indicated that butyrate treatment significantly increased the IC50 value, suggesting heightened drug resistance in HCT15 cells. …”
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