Treatment Interruption and Regimen Change in Firstgeneration versus Second-generation Tyrosine Kinase Inhibitors used as First-line Therapy for Chronic Myeloid Leukemia by Melea A. Ward, Gang Fang, Kristy L. Richards, Christine M. Walko, Stephanie R. Earnshaw, Laura E. Happe, Susan J. Blalock

“…Patients initiating therapy with a 2GTKI had a 48% higher risk of treatment interruption versus patients initiating therapy with a 1GTKI (hazard ratio=1.48, 95% confidence interval 1.08-2.02). The time to treatment interruption was significantly longer in patients initiating therapy with a 1GTKI. …”
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Functional constipation by Yu. O. Shulpekova, A. A. Kurbatova, A. V. Sedova

“…In the section devoted to the bowel diseases the new entity - opioid-induced constipation was defined; besides that diagnostic (mostly - the time-based criteria) of irritable bowel syndrome and functional constipation were modified. …”
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Falling sex ratios and emerging evidence of sex-selective abortion in Nepal: evidence from nationally representative survey data by Mahesh Puri, Melanie Dawn Frost, Peter Richard Andrew Hinde

“…CSRs were looked at over time to assess the impact of legalisation as well as for population sub-groups in order to identify characteristics of women using sex-selection.Results From 2007 to 2010, the CSR for second-order births where the first-born was a girl was found to be 742 girls per 1000 boys (95% CI 599 to 913). …”
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Waterbirds habitat mapping using unmanned aerial vehicle in Belawan Mangrove Ecosystems, North Sumatera, Indonesia by Thoha Achmad Siddik, Fauziyah Laely Nur, Jumilawaty Erni, Marwan Mochammad Akbar

“…The use of Unmanned Aerial Vehicle (UAV) technology can overcome survey constraints for preserving mangrove ecosystems, which have difficult access and take a long time. This study aims to identify waterbirds' habitat in mangrove ecosystems in the Belawan Bird Island area of Medan City using Unmanned Aerial Vehicles (UAV). …”
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Exploring Career Barriers Faced by Female Doctors Due to Gender Bias: A Qualitative Analysis by Anam Zahra, Tayyaba Azhar, Hajra Talat

“…All three authors served as faculty members at FMH College of Medicine & Dentistry, Lahore, during the time this study was conducted. …”
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Coproducing healthcare service improvement for people with common mental health disorders including psychotic experiences: a study protocol of a multiperspective qualitative study by Alexandros Georgiadis, Robbie Duschinsky, Jesus Perez, Peter B Jones, Debra Russo, Clare Knight, Emma Soneson, Mary Dixon-Woods

“…Our sample will include (1) approximately 15 service users who will be receiving therapy or will have completed therapy at the time of recruitment, (2) approximately 15 service users who initiated treatment but withdrew, (3) approximately 15 therapists each with at least 4-month experience in a step-3 IAPT setting and (4) three IAPT managers. …”
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Advanced deep learning techniques for recognition of dental implants by Veena Benakatti, Ramesh P. Nayakar, Mallikarjun Anandhalli, Rohit sukhasare

“…Optimizing this model for a balance between accuracy and efficiency will be necessary for real-time medical imaging applications.…”
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Effects of COVID-19 Emergency Response Levels on Air Quality in the Guangdong-Hong Kong-Macao Greater Bay Area, China by Jie Li, Haotian Yang, Shuping Zha, Nu Yu, Xingang Liu, Ruofei Sun

“…The air quality index and the concentrations of NO2, PM2.5, PM10, and CO in the GBA for 1–19 January 2020 declined 19.4%, 16.7%, 27.5%, 15.8%, and 25.7%, respectively, compared to the same time period in 2016–2019. (2) The reduction in air pollution was strongly associated with the first-level emergency response during this pandemic. …”
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Association between red blood cell distribution width-to-albumin ratio at admission and all-cause mortality in patients with acute pancreatitis based on the MIMIC-III database. by Qingsong Wu, Lianyi Liao, Qingjun Deng

“…Multivariate analysis indicated that potassium levels, total bilirubin, blood urea nitrogen, lactate, partial thromboplastin time, neutrophil and RAR were independently associated with the 28-day mortality. …”
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Impact of invasive and noninvasive pneumococcal diseases on adult populations: risk factors and vaccination status by Hasip Kahraman, Pınar Yıldız, Şenay Yılmaz, Gül Durmaz, Muzaffer Bilgin, Derya Çağlayan

“…Our findings highlight the critical role of comorbidities and intensive care unit admissions in affecting patient outcomes, stressing the importance of timely interventions and enhanced health strategies to improve vaccination rates and overall outcomes in high-risk populations.…”
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Using the Sleeping Beauty Transposon System for Doxycycline-inducible Gene Expression in RAW264.7 Macrophage Cells to Study Phagocytosis by Parsa Kamali, Gregory Fairn

“…Alternative transient approaches, such as electroporation or transduction with lentiviral vectors, typically cause cell death (electroporation) or can be time-consuming to generate numerous lentivirus when using different genes of interest. …”
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Simulation-based validation of a method to detect changes in SARS-CoV-2 reinfection risk. by Belinda Lombard, Harry Moultrie, Juliet R C Pulliam, Cari van Schalkwyk

“…The model's performance was assessed on simulated data representative of the South African SARS-CoV-2 epidemic, reflecting its timing of waves and outbreak magnitude. Model performance under similar scenarios may be different in settings with smaller epidemics (and therefore smaller numbers of reinfections). …”
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A Novel Ensemble Classifier Selection Method for Software Defect Prediction by Xin Dong, Jie Wang, Yan Liang

“…Furthermore, the DFD method is not only highly performant but also requires a small number of base learners to converge rapidly, thereby reducing the amount of data and computation time required.…”
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High-resolution manometry in clinical practice: analysis of esophageal motor function according to Chicago classification by O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…This relatively new diagnostic method was introduced to clinical application in Russian Federation for the first time in 2011. Vasilenko clinic of internal diseases propedeutics, gastroenterology and hepatology (Sechenov University) accumulated significant experience of high-resolution esophageal manometry of overall 1150 studies. …”
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Effect of a closed-loop medication order executive system on safe medication administration at a tertiary hospital: a quasi-experimental study by Xuwen Yin, Haiyan Song, Jieyu Lu, Jing Yang, Rong Wang, Zheng Lin, Shudi Jiang, Hui Yuan, Xumei Wang, Dongmei Xu, Chunhong Gao, Yuan Zhou, Jiayi Xu, Chen Chen, Chenyu Gu, Qingqing Diao, Fang Li, Zejuan Gu

“…The autoregressive integrated moving average (ARIMA) model in time-series analysis was used to evaluate the level and trend changes in ME rates using SPSS 25.0 before and after system implementation. …”
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The minimal clinically important difference of the Participation Measurement Scale in chronic stroke by Oyéné Kossi, Soraia M. Silva, Francesco Lena, Mendinatou Agbetou, Thierry Adoukonou, Peter Feys, Félix Nindorera

“…Results: Data were collected from 46 people with chronic stroke, of which 22% were female, with median (Percentile 25, Percentile 75) age of 54 (44; 60) years, and time since stroke is 24 (11; 37) months. For all participants, the PM-Scale measures range from –2.98 logits to 5.02 logits. …”
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INCREASING VALUE-BASED COMPANY POTENTIAL: THE GROUNDS OF A FULL-SCALE ASSESSMENT by Romans Dyakons, Vsevolods Karajevs, Rostislavs Kopitovs

“…The objective of methodological foundations is to facilitate the timely identification of potential vulnerabilities that could lead to future losses in sustainability. …”
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Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

“…Organismal behavioral testing is needed to fill the gap, but mammalian studies are too time-consuming and cost-prohibitive for the early stages of drug discovery. …”
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Congenital vitamin D deficiency: presenting with feeding difficulty in early infancy: a case report by Mesfin Wubishet, Tesfa G. Meskel, Kibret Enyew

“…Therefore, clinicians should remain vigilant and maintain a high index of suspicion to ensure timely diagnosis and treatment. It is essential to measure serum calcium and vitamin D levels in both the mother and infant, particularly for newborns of high-risk mothers, such as those who wear conservative religious clothing like a niqab. …”
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Estimating the Economic and Clinical Value of Reducing Antimicrobial Resistance to Three Gram-negative Pathogens in Japan by Tetsuya Matsumoto, Oliver Darlington, Ryan Miller, Jason Gordon, Phil McEwan, Takahisa Ohashi, Amer Taie, Akira Yuasa

“…The model used a 10-year time horizon with a willingness-to-pay threshold of ¥5 000 000 (US $46 827) and discounting was applied at a rate of 2% to costs and benefits. …”
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